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Condea verticillata

Table of Contents

Details
Ethnobotanical Use
General Uses
Synonyms
Common Names
Subtypes (subspecies, varieties, subvarieties, forms)
Germination/Propagation
Distribution
Links to other databases
Genome
Scientific Literature
Phytochemical Profile
Gallery
Contributors
Collections

Details Top

Internal ID UUID64405f086503f188407568
Scientific name Condea verticillata
Authority (Jacq.) Harley & J.F.B.Pastore
First published in Phytotaxa 58: 15 (2012)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Condea verticillata, long recognized in the Neotropics as a household remedy for colic, diarrhea, respiratory colds, and fever, is most often prepared as a simple leaf infusion or decoction. In the Guianas, people take a mild leaf tea to soothe infant colic and diarrhea (Plotkin, 1993; Plotkin and Tilney, 1991). Across northern South America, a leaf decoction is used for colds, flu, and fevers (León, 1994). In Panama, a fresh‑leaf tea is drunk as an expectorant for coughs and is also given to children during colds (Duke, 1994). Each preparation consistently centers on the leaves, with the infusion taken warm and the decoction short‑boiled, indicating a broad reliance on aqueous extracts for gastrointestinal and respiratory complaints.

A practical and historically common recipe is the mild leaf tea: take 10 g of fresh leaves (about 2 tablespoons loosely packed), pour 250 mL of near‑boiling water over them, cover, and steep for 10–15 minutes; strain and sip one cup up to three times a day. For a stronger preparation, use the same leaf amount with 200 mL water and simmer gently for 5 minutes after bringing to a boil, then steep uncovered for an additional 5 minutes; this version is typically taken once or twice daily. Some communities also use a leaf infusion as a topical wash for mild skin irritations. Given its strong aroma, adults should start with small amounts and avoid prolonged daily use; children should receive only very gentle infusions at modest strength; and pregnant or nursing individuals should avoid internal use unless advised by a qualified practitioner.

The activity is plausibly related to the plant’s essential oil (rich in 1,8‑cineole, limonene, and α‑pinene) and to common phenolics such as rosmarinic acid. These constituents are well established for this species and align with the expectorant, spasmolytic, and antimicrobial qualities observed in traditional practice. In addition, the herb’s tannins contribute to its astringent action used in gastrointestinal applications.

Today, dried leaf preparations remain available in local markets of northern South America, and scientific studies continue to corroborate antibacterial and spasmolytic effects (e.g., Dolder et al., 2012).

General Uses Top

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Synonyms Top

Scientific name Authority First published in
Hyptis axillaris Fernald Proc. Amer. Acad. Arts 35: 565 (1900)
Hyptis parviflora M.Martens, & Galeotti Bull. Acad. Roy. Sci. Bruxelles 11(2): 186 (1844)
Hyptis pringlei Fernald Proc. Amer. Acad. Arts 35: 565 (1900)
Hyptis verticillata Jacq. Collectanea 1: 101 (1787)
Mentha hyptiformis Lam. Encycl. 4: 110 (1797)
Mesosphaerum verticillatum Kuntze Revis. Gen. Pl. 2: 525 (1891)
Stachys patens Sw. Prodr. Veg. Ind. Occ. : 88 (1788)

Common names Top

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Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Northern America
    • Mexico
      • Mexico Central
      • Mexico Gulf
      • Mexico Northeast
      • Mexico Southeast
      • Mexico Southwest
    • Southeastern U.S.A.
      • Florida
  • Southern America
    • Caribbean
      • Cuba
      • Dominican Republic
      • Haiti
      • Jamaica
      • Leeward Islands
      • Puerto Rico
      • Southwest Caribbean
      • Trinidad-Tobago
      • Windward Islands
    • Central America
      • Belize
      • Costa Rica
      • El Salvador
      • Guatemala
      • Honduras
      • Nicaragua
      • Panamá
    • Northern South America
      • Venezuela
    • Western South America
      • Colombia
      • Ecuador

Links to other databases Top

Suggest others/fix!
Database ID/link to page
World Flora Online wfo-0001333563
Florida Plant Atlas 494
Tropicos 100381984
INPN 851857
KEW urn:lsid:ipni.org:names:77120819-1
Open Tree Of Life 1062465
NCBI Taxonomy 986250
IPNI 77120819-1
iNaturalist 489288
GBIF 7942529
USDA GRIN 466110
Wikipedia Condea_verticillata
CMAUP NPO17947

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Larvicidal Potential of Caribbean Plants Layne-Yarde RN, Sandiford SL Biomed Res Int 26-Aug-2023
PMCID:PMC10474962
doi:10.1155/2023/5518863
PMID:37663786
Inhibition of the CYP Enzymatic System Responsible of Heterocyclic Amines Bioactivation by an Asclepias subulata Extract Gutiérrez-Pacheco SL, Peña-Ramos EA, Santes-Palacios R, Valenzuela-Melendres M, Hernández-Mendoza A, Burgos-Hernández A, Robles-Zepeda RE, Espinosa-Aguirre JJ Plants (Basel) 17-Jun-2023
PMCID:PMC10305697
doi:10.3390/plants12122354
PMID:37375979
Application of Rosmarinic Acid with Its Derivatives in the Treatment of Microbial Pathogens Kernou ON, Azzouz Z, Madani K, Rijo P Molecules 22-May-2023
PMCID:PMC10220798
doi:10.3390/molecules28104243
PMID:37241981
Chemistry and Biological Activities of Naturally Occurring and Structurally Modified Podophyllotoxins Jin L, Song Z, Cai F, Ruan L, Jiang R Molecules 30-Dec-2022
PMCID:PMC9822336
doi:10.3390/molecules28010302
PMID:36615496
Bioactive compounds of Curvularia species as a source of various biological activities and biotechnological applications Mehta T, Meena M, Nagda A Front Microbiol 08-Dec-2022
PMCID:PMC9777749
doi:10.3389/fmicb.2022.1069095
PMID:36569099
Lignans: a versatile source of anticancer drugs Mukhija M, Joshi BC, Bairy PS, Bhargava A, Sah AN Beni Suef Univ J Basic Appl Sci 04-Jun-2022
PMCID:PMC9166195
doi:10.1186/s43088-022-00256-6
PMID:35694188
Antidiabetic Potential of Plants from the Caribbean Basin Méril-Mamert V, Ponce-Mora A, Sylvestre M, Lawrence G, Bejarano E, Cebrián-Torrejón G Plants (Basel) 20-May-2022
PMCID:PMC9146409
doi:10.3390/plants11101360
PMID:35631785
A Comprehensive Review of Rosmarinic Acid: From Phytochemistry to Pharmacology and Its New Insight Guan H, Luo W, Bao B, Cao Y, Cheng F, Yu S, Fan Q, Zhang L, Wu Q, Shan M Molecules 20-May-2022
PMCID:PMC9143754
doi:10.3390/molecules27103292
PMID:35630768
Traditional Uses, Phytochemistry, and Bioactivities of Mesosphaerum suaveolens (L.) Kuntze Almeida-Bezerra JW, Rodrigues FC, Lima Bezerra JJ, Vieira Pinheiro AA, Almeida de Menezes S, Tavares AB, Costa AR, Augusta de Sousa Fernandes P, Bezerra da Silva V, Martins da Costa JG, Pereira da Cruz R, Bezerra Morais-Braga MF, Melo Coutinho HD, Teixeira de Albergaria E, Meiado MV, Siyadatpanah A, Kim B, Morais de Oliveira AF Evid Based Complement Alternat Med 10-Mar-2022
PMCID:PMC8930220
doi:10.1155/2022/3829180
PMID:35310039
Subtribe Hyptidinae (Lamiaceae): A promising source of bioactive metabolites Bridi H, de Carvalho Meirelles G, Lino von Poser G J Ethnopharmacol 05-Aug-2020
PMCID:PMC7403033
doi:10.1016/j.jep.2020.113225
PMID:32763419
Traditional Herbal Medicine in Mesoamerica: Toward Its Evidence Base for Improving Universal Health Coverage Geck MS, Cristians S, Berger-González M, Casu L, Heinrich M, Leonti M Front Pharmacol 31-Jul-2020
PMCID:PMC7411306
doi:10.3389/fphar.2020.01160
PMID:32848768
Exchange of medicinal plant information in California missions McBride JR, Cavero RY, Cheshire AL, Calvo MI, McBride DL J Ethnobiol Ethnomed 15-Jun-2020
PMCID:PMC7296748
doi:10.1186/s13002-020-00388-y
PMID:32539795
Synthesis of Cyclic β-Silylalkenyl Triflates via an Alkenyl Cation Intermediate Lee CJ, Swain M, Kwon O Org Lett 17-Aug-2018
PMCID:PMC6133754
doi:10.1021/acs.orglett.8b02398
PMID:30118234
Inhibition of Cytochrome P450 Activities by Extracts of Hyptis verticillata Jacq.: Assessment for Potential HERB-Drug Interactions Picking D, Chambers B, Barker J, Shah I, Porter R, Naughton DP, Delgoda R Molecules 15-Feb-2018
PMCID:PMC6017200
doi:10.3390/molecules23020430
PMID:29462868
Potential of Traditional Knowledge of Plants in the Management of Arthropods in Livestock Industry with Focus on (Acari) Ticks Wanzala W Evid Based Complement Alternat Med 17-Jul-2017
PMCID:PMC5536150
doi:10.1155/2017/8647919
PMID:28798806

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lignans, neolignans and related compounds / Arylnaphthalene lignans
5-Methoxydehydropodophyllotoxin 133997 Click to see 440.40 unknown https://doi.org/10.1021/NP50100A011
Dehydro-beta-peltatin methyl ether 44584484 Click to see COC1=CC(=CC(=C1OC)OC)C2=C3C(=CC4=C(C5=C(C=C42)OCO5)OC)COC3=O 424.40 unknown https://doi.org/10.1021/NP50100A011
Dehydropodophyllotoxin 5316463 Click to see 410.40 unknown https://doi.org/10.1021/NP50100A011
https://doi.org/10.1016/S0031-9422(00)97101-2
https://doi.org/10.1055/S-2006-958061
Deoxydehydropodophyllotoxin 10500814 Click to see 394.40 unknown https://doi.org/10.1016/S0031-9422(00)97101-2
https://doi.org/10.1021/NP50100A011
> Lignans, neolignans and related compounds / Furanoid lignans / Tetrahydrofuran lignans / 9,9-epoxylignans / Dibenzylbutyrolactone lignans
(3S,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(R)-hydroxy-(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one 173676 Click to see 416.40 unknown https://doi.org/10.1055/S-2006-958061
https://doi.org/10.1016/S0031-9422(00)97101-2
4-[(2H-1,3-Benzodioxol-5-yl)methyl]-3-[hydroxy(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one 323437 Click to see 416.40 unknown https://doi.org/10.1016/S0031-9422(00)97101-2
rel-(3R,4S)-4-(1,3-Benzodioxol-5-ylmethyl)dihydro-3-((R)-hydroxy(3,4,5-trimethoxyphenyl)methyl)-2(3H)-furanone 9931715 Click to see 416.40 unknown https://doi.org/10.1016/S0031-9422(00)97101-2
https://doi.org/10.1055/S-2006-958061
Yatein 442835 Click to see 400.40 unknown https://doi.org/10.1021/NP50100A011
> Lignans, neolignans and related compounds / Lignan lactones
(5aS,8aS,9R)-4-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one 7059494 Click to see COC1=CC(=CC(=C1OC)OC)C2C3C(CC4=C(C5=C(C=C24)OCO5)O)COC3=O 414.40 unknown https://doi.org/10.1002/JPS.2600600442
(5R,5aS,8aS)-5-(4-hydroxy-3,5-dimethoxyphenyl)-5a,8,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-6-one 124306216 Click to see 384.40 unknown https://doi.org/10.1002/JPS.2600600442
(8aR)-4-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one 5320458 Click to see 414.40 unknown https://doi.org/10.1021/NP50018A023
10-Hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one 2363 Click to see 414.40 unknown https://doi.org/10.1002/JPS.2600600442
4'-Demethyldeoxypodophyllotoxin 160705 Click to see 384.40 unknown https://doi.org/10.1021/NP50100A011
5-(4-hydroxy-3,5-dimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one 1689 Click to see COC1=CC(=CC(=C1O)OC)C2C3C(CC4=CC5=C(C=C24)OCO5)COC3=O 384.40 unknown https://doi.org/10.1002/JPS.2600600442
beta-Peltatin 92122 Click to see 414.40 unknown https://doi.org/10.1021/NP50018A023
Deoxypicropodophyllotoxin 11711021 Click to see COC1=CC(=CC(=C1OC)OC)C2C3C(CC4=CC5=C(C=C24)OCO5)COC3=O 398.40 unknown https://doi.org/10.1021/NP50100A011
Deoxypodophyllotoxin 345501 Click to see COC1=CC(=CC(=C1OC)OC)C2C3C(CC4=CC5=C(C=C24)OCO5)COC3=O 398.40 unknown https://doi.org/10.1021/NP50100A011
Isodeoxypodophyllotoxin 332809 Click to see 398.40 unknown https://doi.org/10.1021/NP50100A011
> Lignans, neolignans and related compounds / Lignan lactones / Podophyllotoxins
(5R,5aS,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one 4865 Click to see 414.40 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685770/
https://doi.org/10.1055/S-2006-958061
https://doi.org/10.1016/S0031-9422(00)97101-2
(5S,5aR,8aR,9R)-5-hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one 500181 Click to see 400.40 unknown https://doi.org/10.1016/S0031-9422(00)97101-2
https://doi.org/10.1055/S-2006-958061
4'-Demethylpodophyllotoxin 122667 Click to see 400.40 unknown https://doi.org/10.1055/S-2006-958061
https://doi.org/10.1016/S0031-9422(00)97101-2
Podofilox 10607 Click to see COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O 414.40 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685770/
https://doi.org/10.1055/S-2006-958061
https://doi.org/10.1016/S0031-9422(00)97101-2
https://doi.org/10.1021/NP50100A011
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Aromatic monoterpenoids
Thymol 6989 Click to see 150.22 unknown https://doi.org/10.1055/S-2006-958061
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Bicyclic monoterpenoids
(-)-beta-Pinene 440967 Click to see 136.23 unknown https://doi.org/10.1055/S-2006-958061
(+-)-alpha-Pinene 6654 Click to see 136.23 unknown https://doi.org/10.1055/S-2006-958061
alpha-Pinene, (+)- 82227 Click to see 136.23 unknown https://doi.org/10.1055/S-2006-958061
Beta-Pinene 14896 Click to see 136.23 unknown https://doi.org/10.1055/S-2006-958061
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
Cadina-4,10(15)-dien-3-one 56842265 Click to see 218.33 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Aromadendrane sesquiterpenoids / 5,10-cycloaromadendrane sesquiterpenoids
Squamulosone 636442 Click to see 218.33 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(+)-Ursolic Acid 64945 Click to see 456.70 unknown https://doi.org/10.1021/NP50100A011
Corosolic Acid 6918774 Click to see 472.70 unknown https://doi.org/10.1021/NP50100A011
Maslinic Acid 73659 Click to see 472.70 unknown https://doi.org/10.1021/NP50100A011
Oleanolic Acid 10494 Click to see 456.70 unknown https://doi.org/10.1021/NP50100A011
> Organoheterocyclic compounds / Naphthofurans / Furanonaphthodioxoles
(5R)-5-(3,4,5-trimethoxyphenyl)-6,9-dihydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one 101663383 Click to see COC1=CC(=CC(=C1OC)OC)C2C3=C(CC4=CC5=C(C=C24)OCO5)C(=O)OC3 396.40 unknown https://doi.org/10.1016/S0031-9422(00)97101-2
https://doi.org/10.1055/S-2006-958061
(5R)-5,9-Dihydro-5-(3,4,5-trimethoxyphenyl)furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(8H)-one 6452099 Click to see 396.40 unknown https://doi.org/10.1021/NP50100A011
5-(3,4,5-trimethoxyphenyl)-6,9-dihydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one 71502738 Click to see 396.40 unknown https://doi.org/10.1016/S0031-9422(00)97101-2
> Organoheterocyclic compounds / Pyrrolidines / Pyrrolidones / Pyrrolidine-2-ones
(R)-5-Hydroxy-2-pyrrolidinone 178119 Click to see C1CC(=O)NC1O 101.10 unknown https://doi.org/10.1055/S-2006-958061
5-Hydroxypyrrolidin-2-one 194148 Click to see C1CC(=O)NC1O 101.10 unknown https://doi.org/10.1055/S-2006-958061
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives
(S)-Rosmarinic acid 639655 Click to see 360.30 unknown https://doi.org/10.1016/S0031-9422(00)97101-2
3-(3,4-Dihydroxyphenyl)-2-[3-(3,4-dihydroxyphenyl)prop-2-enoyloxy]propanoic acid 5099 Click to see C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O 360.30 unknown https://doi.org/10.1016/S0031-9422(00)97101-2
Rosmarinic Acid 5281792 Click to see 360.30 unknown https://doi.org/10.1055/S-2006-958061
https://doi.org/10.1016/S0031-9422(00)97101-2
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 8-O-methylated flavonoids
Sideritoflavone 155493 Click to see COC1=C(C(=C2C(=C1O)C(=O)C=C(O2)C3=CC(=C(C=C3)O)O)OC)OC 360.30 unknown https://doi.org/10.1016/S0031-9422(00)97101-2
https://doi.org/10.1021/NP50100A011
https://doi.org/10.1055/S-2006-958061

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