Aspidosperma quebracho-blanco

Details Top

Internal ID UUID643fea7380406426614155
Scientific name Aspidosperma quebracho-blanco
Authority Schltdl.
First published in Bot. Zeitung (Berlin) 19: 137 (1861)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Aspidosperma quebracho-blanco, the brittlewood known as quebracho blanco, is a key medicinal tree in the southern South American lowlands and highlands. Across Bolivia and northwestern Argentina, healers have long used infusions and decoctions of the bark to ease coughs, asthma, and bronchial complaints. Among traditional Mapuche groups of southern Chile, the leaves and young twigs were occasionally steeped as a tea for cough and bronchial irritation (Bennett et al., 2021). An earlier survey in the Chaco reported bark infusions for the same respiratory indications (Mooney & Godfrey, 1946), and ethnobotanical work in Argentina records quebracho blanco bark decoctions as a common remedy for chronic bronchitis and asthma (Martínez Crovetto, 1964).

These preparations remain current in several communities. In Bolivia’s Gran Chaco, healers use bark infusions for cough and asthma (Alonso & Desmarchelier, 2005), and in Argentine Patagonia the same bark decoction is employed for bronchitis (Van den Berg & Van Epen, 1992). For the most common traditional preparation, a mild bark tea is the guide. Use 3–5 grams of clean, ground quebracho blanco bark and pour 250 milliliters of just-boiled water over it. Cover and let it steep for 15–20 minutes, then strain. Drink one small cup (about 100–120 milliliters) 1–2 times a day for several days as needed. Because the bark contains indole alkaloids and other constituents with potential toxicity, limit use to short courses; do not exceed 3–5 grams per day; do not use in pregnancy or during breastfeeding; and consult a healthcare professional before combining it with other medications.

Phytochemical work from the 20th century identified indole alkaloids—including quebrachamine—in quebracho blanco bark (Roth & Beck, 1936; Döpke, 1971), which plausibly underpin the plant’s long‑standing reputation for easing bronchial irritation. Modern interest remains steady: recent ethnobotanical surveys still record quebracho blanco bark infusions for cough and asthma, and the tincture is occasionally listed in contemporary herbal compendia, while research continues on the pharmacology of its indole alkaloids and related species (Alonso & Desmarchelier, 2005; Bennett et al., 2021).

General Uses Top

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Common products:
The principal industrial products derived from Aspidosperma quebracho-blanco are tannins extracted from the heartwood/bark for leather tanning and construction-grade timber and poles.

Industrial and craft applications:
The wood’s high density, strength, and durability make it suitable for heavy-duty applications such as structural timber, posts, and poles; it is also used as a charcoal feedstock. Tannins from the heartwood/bark function as tanning agents in leather production and as brown colorants for protein fibers.

Wood and fiber:
Heartwood and bark contain condensed tannins (proanthocyanidins). Extracts are used for leather tanning; the same tannins produce brown dyes for protein fibers (wool/silk).

Colorants and tanning:
Natural brown dyes for protein fibers; condensed tannin extracts used in vegetable tanning of leather.

Properties relevant to use:
The wood is dense (typically exceeds 1.0 g/cm3) and strong, conferring durability for load-bearing and outdoor uses. Bark and heartwood tannins are condensed (proanthocyanidin) polyphenols that complex with collagen and protein fibers, forming stable brown color and leather retanning effects.

Standards and regulation:
Tannin products for leather are subject to relevant national regulations for industrial chemicals and food-contact articles; timber is regulated for grading and grading and durability classification according to national standards where marketed.

Sustainability and sourcing:
The species is native to dry forests of the Gran Chaco. Supply is primarily from wild harvest; conservation concerns have been noted in parts of its range, leading to interest in sustainable extraction and certified sourcing of both wood and tannin products.

Synonyms Top

Scientific name Authority First published in
Macaglia quebracho Kuntze Revis. Gen. Pl. 2: 416 (1891)
Macaglia quebracho-blanco (Schltdl.) A.Lyons Pl. Nam. , ed. 2: 286 (1907)
Aspidosperma crotalorum Speg. Physis (Buenos Aires) 3: 334 (1917)
Aspidosperma quebracho Griseb. Pl. Lorentz. : 155 (1874)
Aspidosperma quebracho-blanco var. ellipticum Markgr. Notizbl. Bot. Gart. Berlin-Dahlem 12: 300 (1935)
Aspidosperma quebracho-blanco f. malmeanum Markgr. Notizbl. Bot. Gart. Berlin-Dahlem 13: 467 (1937)
Aspidosperma quebracho-blanco var. pendulum Speg. in Speg. & Girola Anales Soc. Rural Argent. 1910: 391 (1910)
Aspidosperma quebracho-blanco f. schlechtendalianum Markgr. Notizbl. Bot. Gart. Berlin-Dahlem 13: 467 (1937)
Aspidosperma quebracho-blanco f. spegazzinianum Markgr. Notizbl. Bot. Gart. Berlin-Dahlem 13: 467 (1937)
Aspidosperma quebrachoideum Rojas Acosta Essai Therap. Vég. Corrientes : 21 (1913)

Common names Top

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Language Common/alternative name
Spanish macaglia quebracho-blanco
Spanish macaglia quebracho
Spanish aspidosperma crotalorum
Spanish quebracho blanco
Catalan quebratxo blanc
German quebracho blanco
Esperanto kebraĉa aspidospermao
Esperanto blanka kebraĉo
Basque kebratxo
French quebracho blanc
Italian quebracho bianco
Lithuanian baltasis kvebrachas
Polish quebracho białe
Quechua k'acha-k'acha
Quechua yuraq paaq
Quechua yuraq pawaq
Quechua yuraq q'acha-q'acha
Russian Аспидосперма квебрахо-бланко
Russian Белое квебрахо
Vietnamese mẻ rìu
Chinese 白坚木
Chinese 白堅木

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Southern America
    • Brazil
      • Brazil West-central
    • Southern South America
      • Argentina Northeast
      • Argentina Northwest
      • Paraguay
      • Uruguay
    • Western South America
      • Bolivia

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000291496
UNII 4MXM780YH3
Tropicos 1802205
KEW urn:lsid:ipni.org:names:77440-1
The Plant List kew-17346
Open Tree Of Life 619034
NCBI Taxonomy 141536
IUCN Red List 61360735
IPNI 77440-1
iNaturalist 424099
GBIF 7316860
Freebase /m/0837d2
EPPO ASOQU
EOL 6852109
USDA GRIN 5585
Wikipedia Aspidosperma_quebracho-blanco

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Isolation of Two New Nitrogenous Metabolites from the Cultured Cells of Aspidosperma Quebracho-Blanco Norio Aimi, Naoki Uchida, Naoko Oya, Shin-ichiro Sakai, Luis A. Mendonza, Peter Obitz, Joachim St喞kigt The Japan Institute of Heterocyclic Chemistry 31-Mar-2009
doi:10.3987/COM-94-6851
�ber neue Alkaloide aus der Rinde von Aspidosperma Quebracho blanco Schlecht Paul Tunmann, Josef Rachor Springer Science and Business Media LLC 26-Nov-2004
doi:10.1007/BF00638293
Novel indole alkaloids from cell suspension cultures of aspidosperma quebracho blanco schlecht Norio Aimi, Naoki Uchida, Naoko Ohya, Hajime Hosokawa, Hiromitsu Takayama, Shin-ichiro Sakai, Luis A. Mendonza, Leo Polz, Joachim Stöckigt Elsevier BV 25-Jul-2002
doi:10.1016/S0040-4039(00)93504-4
Alkaloids of Aspidosperma pyrifolium A.A. Craveiro, F.J.A. Matos, Leila M. Serur Elsevier BV 25-Jul-2002
doi:10.1016/S0031-9422(00)84061-3
The structure elucidation of Rhazinilam, a new class of Alkaloids from the apocynaceae, by X-ray analysis D.J. Abraham, R.D. Rosenstein, R.L. Lyon, H.H.S. Fong Elsevier BV 25-Jul-2002
doi:10.1016/S0040-4039(01)84471-3
Isolation and biological activity of aspidospermine and quebrachamine from an Aspidosperma tree source. Deutsch HF, Evenson MA, Drescher P, Sparwasser C, Madsen PO J Pharm Biomed Anal 01-Oct-1994
doi:10.1016/0731-7085(94)00066-2
PMID:7841224
Biological and phytochemical evaluation of plants. XII. Isolation of acetylakuammidine from Aspidosperma quebracho-blanco leaves. Lyon RL, Fong HH, Farnsworth NR J Pharm Sci 01-May-1973
doi:10.1002/JPS.2600620534
PMID:4705700
Biological and phytochemical evaluation of plants. XI. Isolation of aspidospermine, quebrachidine, rhazinilam, (-)-pyrifolidine, and akuammidine from Aspidosperma quebracho-blanco (Apocynaceae). Lyon RL, Fong HH, Farnsworth NR, Svoboda GH J Pharm Sci 01-Feb-1973
doi:10.1002/JPS.2600620206
PMID:4686392

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Aspidospermatan-type alkaloids
(-)-Pyrifolidine 579923 Click to see 384.50 unknown https://doi.org/10.1002/JPS.2600620206
(1R,9R,12R,19R)-12-ethyl-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6-triene 16079154 Click to see 296.40 unknown https://doi.org/10.1002/JPS.2600620206
1-Acetyl-17-methoxyaspidospermidine 579922 Click to see CCC12CCCN3C1C4(CC3)C(CC2)N(C5=C4C=CC=C5OC)C(=O)C 354.50 unknown https://doi.org/10.1016/S0031-9422(00)84061-3
Aspidospermine 227613 Click to see 354.50 unknown https://doi.org/10.1016/0731-7085(94)00066-2
https://doi.org/10.1002/JPS.2600620206
https://doi.org/10.1002/JPS.2600620534
Deacetylaspidospermine 580302 Click to see 312.40 unknown https://doi.org/10.1002/JPS.2600620206
> Alkaloids and derivatives / Corynanthean-type alkaloids
methyl (1R,9S,10S,12S,13E,16S,17R,18S)-13-ethylidene-18-hydroxy-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2,4,6-triene-17-carboxylate 11870794 Click to see CC=C1CN2C3CC1C4(C2CC5(C3NC6=CC=CC=C65)C4O)C(=O)OC 352.40 unknown https://doi.org/10.1007/BF00638293
> Alkaloids and derivatives / Eburnan-type alkaloids
(15R,19S)-15-Ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraen-17-one 6973664 Click to see 294.40 unknown https://doi.org/10.1002/JPS.2600620206
Vinburnine 71203 Click to see CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(=O)C2 294.40 unknown https://doi.org/10.1002/JPS.2600620206
> Alkaloids and derivatives / Macroline alkaloids
19-(Z)-Akuammidine 138113962 Click to see CC=C1CN2C3CC1C(C2CC4=C3NC5=CC=CC=C45)(CO)C(=O)OC 352.40 unknown https://doi.org/10.1002/JPS.2600620206
methyl (1S,14S,15Z)-13-(acetyloxymethyl)-15-ethylidene-3,17-diazapentacyclo[12.3.1.02,10.04,9.012,17]octadeca-2(10),4,6,8-tetraene-13-carboxylate 101287854 Click to see 394.50 unknown https://doi.org/10.1002/JPS.2600620534
> Alkaloids and derivatives / Quebrachamine alkaloids
Quebrachamine 92990 Click to see CCC12CCCN(C1)CCC3=C(CC2)NC4=CC=CC=C34 282.40 unknown https://doi.org/10.1002/JPS.2600620206
https://doi.org/10.1016/0731-7085(94)00066-2
> Alkaloids and derivatives / Strychnos alkaloids
(1R,9R,11R,17R,18E)-18-ethylidene-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6-triene 101286225 Click to see CC=C1C2CCN3C1C4(CC3)C(C2)NC5=CC=CC=C45 266.40 unknown https://doi.org/10.1002/JPS.2600620206
11-Hydroxytubotaiwine 131752942 Click to see 340.40 unknown https://doi.org/10.3987/COM-94-6851
methyl (1S,11S,17R,18R)-18-ethyl-5-hydroxy-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2(7),3,5,9-tetraene-10-carboxylate 163043342 Click to see CCC1C2CCN3C1C4(CC3)C5=C(C=C(C=C5)O)NC4=C2C(=O)OC 340.40 unknown https://doi.org/10.3987/COM-94-6851
> Benzenoids
(R)-Rhazinilam 160263 Click to see 294.40 unknown https://doi.org/10.1002/JPS.2600620206
Rhazinilam 11312435 Click to see 294.40 unknown https://doi.org/10.1002/JPS.2600620206
https://doi.org/10.1016/S0040-4039(01)84471-3
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Hydroxysteroids / 21-hydroxysteroids
Desoxycortone 6166 Click to see CC12CCC3C(C1CCC2C(=O)CO)CCC4=CC(=O)CCC34C 330.50 unknown https://doi.org/10.1002/JPS.2600620206
> Organic acids and derivatives / Carboxylic acids and derivatives / Amino acids, peptides, and analogues / Alpha amino acids and derivatives
(S,Z)-3-Ethylidenehexahydropyrrolo[1,2-a]pyrazine-1,4-dione 13876565 Click to see 180.20 unknown https://doi.org/10.3987/COM-94-6851
3-Ethylidene-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazine-1,4-dione 71435375 Click to see CC=C1C(=O)N2CCCC2C(=O)N1 180.20 unknown https://doi.org/10.3987/COM-94-6851
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / 1,3-dicarbonyl compounds / Beta-diketones
2-(4-Butanoyl-3,5-dioxooxolan-2-yl)acetic acid 163037595 Click to see 228.20 unknown https://doi.org/10.1002/JPS.2600620206
https://doi.org/10.1002/JPS.2600620534
> Organoheterocyclic compounds / Indoles and derivatives / Indoles / 3-alkylindoles
(1S,16R)-1-ethyl-15-oxa-5,18-diazatetracyclo[14.3.1.04,12.06,11]icosa-4(12),6,8,10-tetraene-14,17-dione 134830560 Click to see 326.40 unknown https://doi.org/10.1016/S0040-4039(00)93504-4
4,8-Methano(1,4)oxaazacyclododecino(9,10-b)indole-2,5(1H,4H)-dione, 8-ethyl-6,7,8,9,10,11-hexahydro- 85634496 Click to see 326.40 unknown https://doi.org/10.1016/S0040-4039(00)93504-4
> Organoheterocyclic compounds / Indoles and derivatives / Pyrroloindoles
Rhazidine 3084227 Click to see 299.40 unknown https://doi.org/10.1002/JPS.2600620206
> Phenylpropanoids and polyketides / 2-arylbenzofuran flavonoids
2-(3,4-dihydroxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-5-[3-[2-(4-hydroxyphenyl)ethylamino]-3-oxoprop-1-enyl]-7-methoxy-2,3-dihydro-1-benzofuran-3-carboxamide 85286065 Click to see COC1=CC(=CC2=C1OC(C2C(=O)NCCC3=CC=C(C=C3)O)C4=CC(=C(C=C4)O)O)C=CC(=O)NCCC5=CC=C(C=C5)O 610.70 unknown https://doi.org/10.1002/JPS.2600620206

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