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Details Top

Internal ID UUID643fe144bde53638624621
Scientific name Leuconotis griffithii
Authority Hook.f.
First published in Fl. Brit. India 3: 628 (1882)

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Synonyms Top

Scientific name Authority First published in
Leuconotis elastica Becc. Nelle Forest. Borneo : 358 (1902)
Leuconotis griffithii var. sumatrana Markgr. Blumea 19: 156 (1971)
Leuconotis maingayi Dyer ex Hook.f. Fl. Brit. India 3: 628 (1882)
Leuconotis subavenis Boerl. Bull. Inst. Bot. Buitenzorg 5: 9 (1900)
Leuconotis subavenis var. elastica (Becc.) Markgr. Blumea 19: 156 (1971)

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Varieties (abbr. var.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-tropical
    • Indo-China
      • Thailand
    • Malesia
      • Borneo
      • Malaya
      • Sumatera

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000227294
Tropicos 1804499
KEW urn:lsid:ipni.org:names:79773-1
The Plant List kew-112013
Open Tree Of Life 5745884
IPNI 79773-1
iNaturalist 425696
GBIF 7316616

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
Title Authors Publication Released IDs
Rhazinilam-Leuconolam-Leuconoxine Alkaloids from Leuconotis griffithii. Gan CY, Low YY, Thomas NF, Kam TS J Nat Prod 24-May-2013
doi:10.1021/NP400214Y
PMID:23647487
Leucomidines A–C, novel alkaloids from Leuconotis griffithii Midori Motegi, Alfarius Eko Nugroho, Yusuke Hirasawa, Takashi Arai, A.Hamid A. Hadi, Hiroshi Morita Elsevier BV 03-Jan-2012
doi:10.1016/J.TETLET.2011.12.116
Leucoridines A-D, cytotoxic Strychnos-Strychnos bisindole alkaloids from Leuconotis. Gan CY, Etoh T, Hayashi M, Komiyama K, Kam TS J Nat Prod 25-Jun-2010
doi:10.1021/NP1001187
PMID:20515042
Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii. Hirasawa Y, Shoji T, Arai T, Nugroho AE, Deguchi J, Hosoya T, Uchiyama N, Goda Y, Awang K, Hadi AH, Shiro M, Morita H Bioorg Med Chem Lett 15-Mar-2010
doi:10.1016/J.BMCL.2010.01.051
PMID:20153644
Bisleucocurine A, a novel bisindole alkaloid from Leuconotis griffithii Alfarius E. Nugroho, Yusuke Hirasawa, Takahiro Hosoya, Khalijah Awang, A. Hamid A. Hadi, Hiroshi Morita Elsevier BV 25-Feb-2010
doi:10.1016/J.TETLET.2010.02.126
Leuconicines A-G and (-)-eburnamaline, biologically active strychnan and eburnan alkaloids from Leuconotis. Gan CY, Low YY, Etoh T, Hayashi M, Komiyama K, Kam TS J Nat Prod 01-Dec-2009
doi:10.1021/NP900576B
PMID:20035556
Alkaloids of leuconotis griffithii and L. Eugenifolia (Apocynaceae) S.H. Goh, A.Razak Mohd Ali, W.H. Wong Elsevier BV 25-Jul-2002
doi:10.1016/S0040-4020(01)85802-6

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.
Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Aspidofractine alkaloids
Methyl (9R,18R,21S)-2,12-diazahexacyclo[14.2.2.19,12.01,9.03,8.016,21]henicosa-3,5,7-triene-18-carboxylate 21123851 Click to see COC(=O)C1CC23CCCN4C2C5(C1(CC3)NC6=CC=CC=C65)CC4 338.40 unknown https://doi.org/10.1016/S0040-4020(01)85802-6
> Alkaloids and derivatives / Eburnan-type alkaloids
(-)-Eburnamaline 44613905 Click to see CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2O)O 312.40 unknown https://doi.org/10.1021/NP900576B
(+)-Isoeburnamine 118701077 Click to see CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)O 296.40 unknown https://doi.org/10.1016/S0040-4020(01)85802-6
https://doi.org/10.1021/NP900576B
(15R,17R,19R)-15-ethyl-17-methoxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraene 13894860 Click to see CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)OC 310.40 unknown https://doi.org/10.1016/S0040-4020(01)85802-6
(15R,17S,19R)-15-ethyl-17-methoxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraene 13894861 Click to see CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)OC 310.40 unknown https://doi.org/10.1016/S0040-4020(01)85802-6
10-Ethenyl-13-ethyl-7-(15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraen-17-yl)-1,3-diazatetracyclo[11.3.1.02,11.04,9]heptadeca-2,4,6,8,10-pentaen-6-ol 162926560 Click to see CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)C6=C(C=C7C(=C6)C(=C8CC9(CCCN(C9)C8=N7)CC)C=C)O 572.80 unknown https://doi.org/10.1021/NP900576B
12-Ethyl-6-(15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraen-17-yl)-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6-trien-3-ol 75219785 Click to see CCC12CCCN3C1C4(CC3)C(CC2)NC5=C(C=CC(=C45)O)C6CC7(CCCN8C7C9=C(CC8)C1=CC=CC=C1N69)CC 576.80 unknown https://doi.org/10.1016/J.BMCL.2010.01.051
15-Ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraene-16,17-diol 75082689 Click to see CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2O)O 312.40 unknown https://doi.org/10.1021/NP900576B
1H-Indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine, 13a-ethyl-2,3,5,6,13a,13b-hexahydro- 610470 Click to see CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C=C2 278.40 unknown https://doi.org/10.1021/NP900576B
https://doi.org/10.1016/J.BMCL.2010.01.051
bisleuconothine A 46881778 Click to see CCC12CCCN3C1C4(CC3)C(CC2)NC5=C(C=CC(=C45)O)C6CC7(CCCN8C7C9=C(CC8)C1=CC=CC=C1N69)CC 576.80 unknown https://doi.org/10.1016/J.BMCL.2010.01.051
CID 163190001 163190001 Click to see CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)O.CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)O 592.80 unknown https://doi.org/10.1021/NP900576B
Eburnamenin-14-ol, 14,15-dihydro-, (14alpha)- 442066 Click to see CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)O 296.40 unknown https://doi.org/10.1016/S0040-4020(01)85802-6
https://doi.org/10.1021/NP900576B
Eburnamenin-14-ol, 14,15-dihydro-, (14beta)- 619344 Click to see CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)O 296.40 unknown https://doi.org/10.1021/NP900576B
Eburnamenin-14(15H)-one 92112 Click to see CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(=O)C2 294.40 unknown https://doi.org/10.1021/NP900576B
Eburnamenine 6857502 Click to see CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C=C2 278.40 unknown https://doi.org/10.1016/J.BMCL.2010.01.051
https://doi.org/10.1021/NP900576B
Eburnamine 101699 Click to see CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)O 296.40 unknown https://doi.org/10.1021/NP900576B
Eburnamonine 3195 Click to see CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(=O)C2 294.40 unknown https://doi.org/10.1021/NP900576B
Leucophyllidine 135908479 Click to see CCC12CCCN3C1C4=C(CC3)C5=CC=CC=C5N4C(C2)C6=C(C=C7C(=C6)C(=C8CC9(CCCN(C9)C8=N7)CC)C=C)O 572.80 unknown https://doi.org/10.1021/NP900576B
> Alkaloids and derivatives / Rhazinilam alkaloids
(12R,19R)-12-ethyl-19-hydroxy-8,16-diazatetracyclo[10.6.1.02,7.016,19]nonadeca-1(18),2,4,6-tetraene-9,17-dione 14442601 Click to see CCC12CCCN3C1(C(=CC3=O)C4=CC=CC=C4NC(=O)CC2)O 326.40 unknown https://doi.org/10.1016/S0040-4020(01)85802-6
(12R,19R)-12-ethyl-8,16-diazatetracyclo[10.6.1.02,7.016,19]nonadeca-1(18),2,4,6-tetraen-9-one 14442607 Click to see CCC12CCCN3C1C(=CC3)C4=CC=CC=C4NC(=O)CC2 296.40 unknown https://doi.org/10.1016/S0040-4020(01)85802-6
(12R,19S)-12-ethyl-19-methoxy-8,16-diazatetracyclo[10.6.1.02,7.016,19]nonadeca-1(18),2,4,6-tetraene-9,17-dione 14442609 Click to see CCC12CCCN3C1(C(=CC3=O)C4=CC=CC=C4NC(=O)CC2)OC 340.40 unknown https://doi.org/10.1016/S0040-4020(01)85802-6
(8R,15R)-15-ethyl-8-hydroxy-1,11-diazapentacyclo[9.7.1.02,7.08,19.015,19]nonadeca-2,4,6-trien-18-one 71712372 Click to see CCC12CCCN3C14C(CC3)(C5=CC=CC=C5N4C(=O)CC2)O 312.40 unknown https://doi.org/10.1021/NP400214Y
(8R,15R)-15-ethyl-8-hydroxy-1,11-diazapentacyclo[9.7.1.02,7.08,19.015,19]nonadeca-2,4,6-triene-10,18-dione 71714599 Click to see CCC12CCCN3C14C(CC3=O)(C5=CC=CC=C5N4C(=O)CC2)O 326.40 unknown https://doi.org/10.1021/NP400214Y
(8S,15R)-15-ethyl-1,11-diazapentacyclo[9.7.1.02,7.08,19.015,19]nonadeca-2,4,6-trien-18-one 72715580 Click to see CCC12CCCN3C14C(CC3)C5=CC=CC=C5N4C(=O)CC2 296.40 unknown https://doi.org/10.1021/NP400214Y
12-Ethyl-19-methoxy-8,16-diazatetracyclo[10.6.1.02,7.016,19]nonadeca-1(18),2,4,6-tetraene-9,17-dione 14442608 Click to see CCC12CCCN3C1(C(=CC3=O)C4=CC=CC=C4NC(=O)CC2)OC 340.40 unknown https://doi.org/10.1016/S0040-4020(01)85802-6
12-Ethyl-8,16-diazatetracyclo[10.6.1.02,7.016,19]nonadeca-1(18),2,4,6-tetraen-9-one 14442606 Click to see CCC12CCCN3C1C(=CC3)C4=CC=CC=C4NC(=O)CC2 296.40 unknown https://doi.org/10.1016/S0040-4020(01)85802-6
Leuconolam 14442600 Click to see CCC12CCCN3C1(C(=CC3=O)C4=CC=CC=C4NC(=O)CC2)O 326.40 unknown https://doi.org/10.1016/S0040-4020(01)85802-6
Leuconolam sesquihydrate 125060 Click to see CCC12CCCN3C1(C(=CC3=O)C4=CC=CC=C4NC(=O)CC2)O 326.40 unknown https://doi.org/10.1016/S0040-4020(01)85802-6
> Alkaloids and derivatives / Strychnos alkaloids
(1R,7S,15R,19S,21S,22S,25S,27R,28S,33S,36S)-28,36-diethyl-26-methylidene-8,18,24,30-tetrazaundecacyclo[25.5.2.218,21.12,24.01,25.07,15.07,22.09,14.015,19.030,33.06,35]heptatriaconta-2(35),3,5,9,11,13-hexaene 163073328 Click to see CCC1CN2CCC34C2CC1C5C3(C6=CC=CC7=C6N(C5)C8C79CCN1C9CC(C8=C)C(C1)CC)NC1=CC=CC=C41 558.80 unknown https://doi.org/10.1016/J.TETLET.2010.02.126
(1S,9S,11S,12S,17S)-12-ethyl-10-methylidene-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6-triene 22213550 Click to see CCC1CN2CCC34C2CC1C(=C)C3NC5=CC=CC=C45 280.40 unknown https://doi.org/10.1016/J.TETLET.2010.02.126
12-Ethyl-6-[(12-ethyl-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6,8-tetraen-10-yl)methyl]-10-methylidene-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2,4,6-triene 75220816 Click to see CCC1CN2CCC34C2CC1C(C3=NC5=CC=CC=C45)CC6=C7C(=CC=C6)C89CCN1C8CC(C(C1)CC)C(=C)C9N7 558.80 unknown https://doi.org/10.1021/NP1001187
28,36-Diethyl-26-methylidene-8,18,24,30-tetrazaundecacyclo[25.5.2.218,21.12,24.01,25.07,15.07,22.09,14.015,19.030,33.06,35]heptatriaconta-2(35),3,5,9,11,13-hexaene 75181675 Click to see CCC1CN2CCC34C2CC1C5C3(C6=CC=CC7=C6N(C5)C8C79CCN1C9CC(C8=C)C(C1)CC)NC1=CC=CC=C41 558.80 unknown https://doi.org/10.1016/J.TETLET.2010.02.126
Akuammicine 10314057 Click to see CC=C1CN2CCC34C2CC1C(=C3NC5=CC=CC=C45)C(=O)OC 322.40 unknown https://doi.org/10.1021/NP900576B
Cur-16-en 544503 Click to see CCC1CN2CCC34C2CC1C(=C)C3NC5=CC=CC=C45 280.40 unknown https://doi.org/10.1016/J.TETLET.2010.02.126
leucoridine D 46898053 Click to see CCC1CN2CCC34C2CC1C(C3=NC5=CC=CC=C45)CC6=C7C(=CC=C6)C89CCN1C8CC(C(C1)CC)C(=C)C9N7 558.80 unknown https://doi.org/10.1021/NP1001187
> Benzenoids
(R)-Rhazinilam 160263 Click to see CCC12CCCN3C1=C(C=C3)C4=CC=CC=C4NC(=O)CC2 294.40 unknown https://doi.org/10.1016/S0040-4020(01)85802-6
Rhazinilam 11312435 Click to see CCC12CCCN3C1=C(C=C3)C4=CC=CC=C4NC(=O)CC2 294.40 unknown https://doi.org/10.1016/S0040-4020(01)85802-6
> Organoheterocyclic compounds / Indoles and derivatives / Carbazoles
(1S,13R)-13-ethyl-20-oxa-9,17-diazapentacyclo[11.7.0.01,17.02,10.03,8]icosa-2(10),3,5,7-tetraene-18,19-dione 101563136 Click to see CCC12CCCN3C1(C4=C(CC2)NC5=CC=CC=C54)OC(=O)C3=O 324.40 unknown https://doi.org/10.1016/J.TETLET.2011.12.116
14-Ethyl-9-oxo-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,10,12(21)-pentaene-10-carboxamide 75058224 Click to see CCC1CN2CCC34C2CC1C5=C3N(C6=CC=CC=C46)C(=O)C(=C5)C(=O)N 361.40 unknown https://doi.org/10.1021/NP900576B
14-Ethyl-9-oxo-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,10,12(21),14-hexaene-10-carboxamide 75082649 Click to see CCC1=CN2CCC34C2CC1C5=C3N(C6=CC=CC=C46)C(=O)C(=C5)C(=O)N 359.40 unknown https://doi.org/10.1021/NP900576B
14-Ethyl-9-oxo-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,10,12(21),14-hexaene-10-carboxylic acid 75082686 Click to see CCC1=CN2CCC34C2CC1C5=C3N(C6=CC=CC=C46)C(=O)C(=C5)C(=O)O 360.40 unknown https://doi.org/10.1021/NP900576B
leuconicine A 44626771 Click to see CCC1CN2CCC34C2CC1C5=C3N(C6=CC=CC=C46)C(=O)C(=C5)C(=O)N 361.40 unknown https://doi.org/10.1021/NP900576B
leuconicine B 46881102 Click to see CCC1CN2CCC34C2CC1C5=C3N(C6=CC=CC=C46)C(=O)C(=C5)C(=O)OC 376.40 unknown https://doi.org/10.1021/NP900576B
leuconicine C 46237100 Click to see CCC1=CN2CCC34C2CC1C5=C3N(C6=CC=CC=C46)C(=O)C(=C5)C(=O)N 359.40 unknown https://doi.org/10.1021/NP900576B
leuconicine E 46881261 Click to see CCC1=CN2CCC34C2CC1C5=C3N(C6=CC=CC=C46)C(=O)C(=C5)C(=O)O 360.40 unknown https://doi.org/10.1021/NP900576B
Melodinine B 44626772 Click to see CCC1=CN2CCC34C2CC1C5=C3N(C6=CC=CC=C46)C(=O)C(=C5)C(=O)OC 374.40 unknown https://doi.org/10.1021/NP900576B
Methyl 14-ethyl-9-oxo-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,10,12(21)-pentaene-10-carboxylate 14442605 Click to see CCC1CN2CCC34C2CC1C5=C3N(C6=CC=CC=C46)C(=O)C(=C5)C(=O)OC 376.40 unknown https://doi.org/10.1021/NP900576B
Methyl 14-ethyl-9-oxo-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2,4,6,10,12(21),14-hexaene-10-carboxylate 75058225 Click to see CCC1=CN2CCC34C2CC1C5=C3N(C6=CC=CC=C46)C(=O)C(=C5)C(=O)OC 374.40 unknown https://doi.org/10.1021/NP900576B
> Organoheterocyclic compounds / Indoles and derivatives / Pyrroloindoles
methyl 3-[(11R,11aS)-11-ethyl-6-oxo-8,9,10,11a-tetrahydro-5H-indolizino[2,1-b]indol-11-yl]propanoate 101563137 Click to see CCC1(CCCN2C1C3=C(C2=O)NC4=CC=CC=C43)CCC(=O)OC 340.40 unknown https://doi.org/10.1016/J.TETLET.2011.12.116
> Organoheterocyclic compounds / Pyridopyrimidines
methyl 3-[(6R)-6-ethyl-11-oxo-8,9-dihydro-7H-pyrido[2,1-b]quinazolin-6-yl]propanoate 101563138 Click to see CCC1(CCCN2C1=NC3=CC=CC=C3C2=O)CCC(=O)OC 314.40 unknown https://doi.org/10.1016/J.TETLET.2011.12.116
> Organoheterocyclic compounds / Pyrrolizines
Nor-rhazinicine 71714596 Click to see CCC12CCC(=O)NC3=CC=CC=C3C4=C1N(C=C4)C(=O)C2 294.30 unknown https://doi.org/10.1021/NP400214Y

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