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Internal ID UUID64404bffb4dbd226073599
Scientific name Primula macrophylla
Authority D.Don
First published in Prodr. Fl. Nepal. : 80 (1825)

Description Top

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Synonyms Top

Scientific name Authority First published in
Primula pulverea Fed. Fl. URSS 18: 727 (1952)
Primula aitchisonii Pax Pflanzenr. , IV, 237: 105 (1905)
Primula laeschkeana A.Kern. ex Kolb. Alpenpfl. : 263 (1890)
Primula jaeschkeana Kern. Nov. Pl. Sp. Dec. 2: 1 (1870)
Aleuritia macrophylla (D.Don) Soják Cas. Nár. Mus., Odd. Prír. 148: 205 (1979 publ. 1980)
Aleuritia pulverea (Fed.) Soják Cas. Nár. Mus., Odd. Prír. 148: 206 (1979 publ. 1980)
Primula purpurea Royle Ill. Bot. Himal. Mts. : 311, t. 77, f. 2 (1836)
Primula nivalis var. macrophylla (D.Don) Pax Monog. 103
Primula stuartii var. purpurea (Royle) Watt
Primula stuartii var. moorcroftiana (Wall. ex Klatt) Watt J. Linn. Soc., Bot. 20: 12, pl. 10 1882
Primula nivalis var. moorcroftiana (Wall. ex Klatt) Pax
Primula meeboldii Pax Repert. Spec. Nov. Regni Veg. 2: 116 (1906)

Common names Top

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Language Common/alternative name
Icelandic hoflykill
Chinese 大叶报春

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Name Authority First published in
Primula macrophylla var. moorcroftiana (Wall. ex Klatt) W.W.Sm. & H.R.Fletcher Trans. Roy. Soc. Edinburgh 60: 590. 1942 (1942)

Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Sow seeds at 20°C, expecting germination within 3 months without further temperature treatment.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • China
      • Tibet
      • Xinjiang
    • Middle Asia
      • Tadzhikistan
    • Western Asia
      • Afghanistan
  • Asia-tropical
    • Indian Subcontinent
      • East Himalaya
      • Nepal
      • Pakistan
      • West Himalaya

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0001105514
Tropicos 26400598
KEW urn:lsid:ipni.org:names:702231-1
The Plant List tro-26400598
Open Tree Of Life 31049
Observations.org 133007
NCBI Taxonomy 487793
IPNI 702231-1
iNaturalist 706645
GBIF 7290591
Elurikkus 642027
USDA GRIN 419878

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
The local medicinal plant knowledge in Kashmir Western Himalaya: a way to foster ecological transition via community-centred health seeking strategies Manzoor M, Ahmad M, Zafar M, Gillani SW, Shaheen H, Pieroni A, Al-Ghamdi AA, Elshikh MS, Saqib S, Makhkamov T, Khaydarov K J Ethnobiol Ethnomed 30-Nov-2023
PMCID:PMC10688143
doi:10.1186/s13002-023-00631-2
PMID:38037066
Edible wild plant species used by different linguistic groups of Kohistan Upper Khyber Pakhtunkhwa (KP), Pakistan Amin M, Aziz MA, Pieroni A, Nazir A, Al-Ghamdi AA, Kangal A, Ahmad K, Abbasi AM J Ethnobiol Ethnomed 13-Feb-2023
PMCID:PMC9923922
doi:10.1186/s13002-023-00577-5
PMID:36782205
Ethnobotanical and antibacterial study of Primula plants traditionally used in the indigenous communities of Western Himalaya, Pakistan Khan S, Shaheen H, Mehmood A, Nasar S, Khan T Saudi J Biol Sci 25-Jan-2022
PMCID:PMC9280169
doi:10.1016/j.sjbs.2022.01.048
PMID:35844385
The response of culturally important plants to experimental warming and clipping in Pakistan Himalayas Karimi S, Nawaz MA, Naseem S, Akrem A, Ali H, Dangles O, Ali Z PLoS One 06-May-2021
PMCID:PMC8101745
doi:10.1371/journal.pone.0237893
PMID:33956795
In Search of High-Yielding and Single-Compound-Yielding Plants: New Sources of Pharmaceutically Important Saponins from the Primulaceae Family Włodarczyk M, Pasikowski P, Osiewała K, Frankiewicz A, Dryś A, Gleńsk M Biomolecules 29-Feb-2020
PMCID:PMC7175136
doi:10.3390/biom10030376
PMID:32121337
Regional trade of medicinal plants has facilitated the retention of traditional knowledge: case study in Gilgit-Baltistan Pakistan Salim MA, Ranjitkar S, Hart R, Khan T, Ali S, Kiran C, Parveen A, Batool Z, Bano S, Xu J J Ethnobiol Ethnomed 28-Jan-2019
PMCID:PMC6348662
doi:10.1186/s13002-018-0281-0
PMID:30691476
Primula vulgaris extract induces cell cycle arrest and apoptosis in human cervix cancer cells Demir S, Turan I, Aliyazicioglu R, Yaman SO, Aliyazicioglu Y J Pharm Anal 28-Jun-2018
PMCID:PMC6190528
doi:10.1016/j.jpha.2018.05.003
PMID:30345144
Comparative ethnobotany of the Wakhi agropastoralist and the Kyrgyz nomads of Afghanistan Soelberg J, Jäger AK J Ethnobiol Ethnomed 06-Jan-2016
PMCID:PMC4702329
doi:10.1186/s13002-015-0063-x
PMID:26739280
Uses of Local Plant Biodiversity among the Tribal Communities of Pangi Valley of District Chamba in Cold Desert Himalaya, India Rana PK, Kumar P, Singhal VK, Rana JC ScientificWorldJournal 17-Feb-2014
PMCID:PMC3947750
doi:10.1155/2014/753289
PMID:24696658
Antibacterial and COX-1 Inhibitory Effect of Medicinal Plants from the Pamir Mountains, Afghanistan Jeppesen AS, Soelberg J, Jäger AK Plants (Basel) 24-Oct-2012
PMCID:PMC4844265
doi:10.3390/plants1020074
PMID:27137641
Phytoecological evaluation with detail floristic appraisal of the vegetation arround Malam Jabba, Swat, Pakistan Rashid A, Swati MF, Sher H, Al-Yemeni MN Asian Pac J Trop Biomed 01-Dec-2011
PMCID:PMC3614209
doi:10.1016/S2221-1691(11)60101-9
PMID:23569814
Isolation of 3,3'-Dihydroxychalcone from Primula macrophylla Viqar Uddin Ahmad, Mohammad Ghani Shah, Mushtaq Noorwala, Faryal Vali Mohammad American Chemical Society (ACS) 17-Mar-2005
doi:10.1021/NP50085A018
Macrophylloside, a flavone glucoside from Primula macrophylla Viqar Uddin Ahmad, Mohammad Ghani Shah, Faryal Vali Mohammad, Nargis Ismail, Mushtaq Noorwala Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(91)83509-J
Macrophyllicinin, a saponin from Primula macrophylla. Ahmad VU, Shah MG J Nat Prod 01-Sep-1993
doi:10.1021/NP50099A018
PMID:8254351
Macrophyllicin, a saponin from Primula macrophylla. Ahmad VU, Shah MG, Mohammad FV, Baqai FT Phytochemistry 01-Apr-1993
doi:10.1016/0031-9422(93)85176-R
PMID:7763557

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Triterpene glycosides / Triterpene saponins
(2S,3S,4S,5R,6R)-6-[[(3S,4aS,5R,6aR,6bS,8R,8aS,12aR,14aR,14bR)-5,8-dihydroxy-8a-(hydroxymethyl)-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-5-[(2S,3R,4S,5R,6R)-3-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydroxyoxane-2-carboxylic acid 162995186 Click to see CC1C(C(C(C(O1)OC2C(C(C(OC2OC3C(C(C(OC3OC4C(C(C(OC4OC5CCC6(C7CC=C8C9CC(CCC9(C(CC8(C7(CC(C6C5(C)C)O)C)C)O)CO)(C)C)C)C(=O)O)O)O)CO)O)O)CO)O)O)O)O)O 1121.30 unknown https://doi.org/10.1016/0031-9422(93)85176-R
6-[[5,8-Dihydroxy-8a-(hydroxymethyl)-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-5-[3-[4,5-dihydroxy-6-(hydroxymethyl)-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydroxyoxane-2-carboxylic acid 162995185 Click to see CC1C(C(C(C(O1)OC2C(C(C(OC2OC3C(C(C(OC3OC4C(C(C(OC4OC5CCC6(C7CC=C8C9CC(CCC9(C(CC8(C7(CC(C6C5(C)C)O)C)C)O)CO)(C)C)C)C(=O)O)O)O)CO)O)O)CO)O)O)O)O)O 1121.30 unknown https://doi.org/10.1016/0031-9422(93)85176-R
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
Macrophyllicin 44150651 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2OC3C(C(C(C(O3)CO)O)O)O)OC4C(C(C(C(O4)CO)O)O)O)C(=O)OC5CCC6(C7CC=C8C9CC(CCC9(C(CC8(C7(CC(C6C5(C)C)O)C)C)O)CO)(C)C)C)O)O)O)O 1121.30 unknown https://doi.org/10.1016/0031-9422(93)85176-R
Macrophyllicinin 44151714 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2OC3C(C(C(C(O3)CO)O)O)O)OC4C(C(C(C(O4)CO)O)O)O)C(=O)OC5CCC6(C7CC=C8C9CC(CCC9(C(CC8(C7(CC(C6C5(C)C)O)C)C)O)COC(=O)C)(C)C)C)O)O)O)O 1163.30 unknown https://doi.org/10.1021/NP50099A018
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
17-(5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 86821 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown https://doi.org/10.1021/NP50085A018
24-Ethylcholest-5-en-3beta-ol 22012 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown https://doi.org/10.1021/NP50085A018
beta-Sitosterol 3-O-beta-D-galactopyranoside 296119 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C 576.80 unknown https://doi.org/10.1016/0031-9422(91)83509-J
Sitogluside 5742590 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C 576.80 unknown https://doi.org/10.1016/0031-9422(91)83509-J
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / O-glycosyl compounds
methyl (1R,4S,9S,11S)-4-hydroxy-9-[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,10-dioxatricyclo[5.3.1.04,8]undec-5-ene-11-carboxylate 101118343 Click to see COC(=O)C1C2C=CC3(C2C(OC1OC3)OC4C(C(C(C(O4)CO)O)O)O)O 404.40 unknown https://doi.org/10.1016/0031-9422(91)83509-J
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides
2-(2-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 15118758 Click to see C1=CC=C(C(=C1)C2=CC(=O)C3=C(O2)C=C(C=C3)OC4C(C(C(C(O4)CO)O)O)O)O 416.40 unknown https://doi.org/10.1016/0031-9422(91)83509-J
2-(2-hydroxyphenyl)-7-[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 163084755 Click to see C1=CC=C(C(=C1)C2=CC(=O)C3=C(O2)C=C(C=C3)OC4C(C(C(C(O4)CO)O)O)O)O 416.40 unknown https://doi.org/10.1016/0031-9422(91)83509-J
2-(2-Hydroxyphenyl)-7-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 74977401 Click to see C1=CC=C(C(=C1)C2=CC(=O)C3=C(O2)C=C(C=C3)OC4C(C(C(C(O4)CO)O)O)O)O 416.40 unknown https://doi.org/10.1016/0031-9422(91)83509-J
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 3-O-methylated flavonoids
3'-Methoxyflavone 619834 Click to see COC1=CC=CC(=C1)C2=CC(=O)C3=CC=CC=C3O2 252.26 unknown https://doi.org/10.1021/NP50085A018
> Phenylpropanoids and polyketides / Linear 1,3-diarylpropanoids / Chalcones and dihydrochalcones / Retrochalcones
3,3'-Dihydroxychalcone 9448219 Click to see C1=CC(=CC(=C1)O)C=CC(=O)C2=CC(=CC=C2)O 240.25 unknown https://doi.org/10.1021/NP50085A018

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