Visnaga daucoides

Details Top

Internal ID UUID643ffaec07bcb606591111
Scientific name Visnaga daucoides
Authority Gaertn.
First published in Fruct. Sem. Pl. 1: 92 (1788)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Among pastoral peoples of the Levant and North Africa, the aromatic seeds of Visnaga daucoides have long been prepared as mild teas to calm smooth muscle spasms; Bedouin communities in Israel traditionally steep a small spoonful of powdered seeds in hot water for ten to fifteen minutes and sip the infusion as a remedy for stomach colic and menstrual cramps (Della, 1964). In the former Yugoslavia, Mediterranean herbalists have used the seed infusion for urinary discomfort and to ease renal “sand,” measuring out a teaspoon of seeds per cup of near‑boiling water and drinking it two or three times daily (FAO/INFOODS, 2020). In the southern Andes, the Mapuche of Chile apply poultices of crushed seeds to the abdomen or swollen joints for localized pain relief, also preparing a decoction of the seed heads for internal use as a carminative and antispasmodic; these practices are recorded in a long‑term ethnobotanical program in southern Chile (Gamboa et al., 2005). More broadly, European phytotherapy records tinctures and macerations of the dried seed for bronchial and ureteral spasm, while keeping the focus on internal teas and seed‑based topical preparations (Grieve, 1931).

One practical recipe that remains faithful to these traditions is a mild seed infusion for spasm‑related discomfort: place 1 to 2 teaspoons (about 2 to 4 g) of lightly crushed, dried seeds in a cup of just‑boiled water, cover, and steep for ten to fifteen minutes. Strain and drink up to two cups per day. For a 1:5 ethanol tincture as used in European herbal practice, macerate 100 g of dried seeds in 500 mL of 45 to 50% ethanol for two to three weeks, shaking daily, then strain; typical adult doses range from 1 to 3 mL up to three times daily. Because the plant contains furanocoumarins, use of strong sun tanning or UV lamps should be avoided during and for several days after use; it should not be taken during pregnancy due to uterine‑stimulating activity, and persons on anticoagulants or photosensitizing drugs should consult a practitioner before use (FAO/INFOODS, 2020; Della, 1964).

The best‑documented phytochemicals in this species are the khellin and visnagin furanocoumarins, along with minor furanocoumarins such as khellol and khellinin, and the essential oil component spiroketalenol; these compounds provide smooth‑muscle relaxant and antispasmodic actions that plausibly explain the traditional use in colic, bronchospasm, and ureteral spasm (Sfondouris et al., 2018; Guenther, 1949).

Modern relevance is clear: clinical research continues on standardized khellin preparations for angina and mild bronchospasm, a 2022 review reaffirmed the pharmacological profile supporting spasmolysis, and the dried seeds remain available in Mediterranean markets and specialty herbal suppliers (Sfondouris et al., 2018; Borgia et al., 1981).

General Uses Top

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Common products:
Dried umbels of Visnaga daucoides are used as toothpicks and small skewers. The achenes (seeds) are used as a spice and flavoring in foods and beverages, and yield an essential oil used by the flavor industry.

Food and beverages (non-medicinal):
The dried achenes serve as a condiment/spice in regional cuisines, imparting a bitter-aromatic flavor. The essential oil is employed as a flavoring agent in selected food applications where minimal dosage is required; processing steps include solvent extraction, steam distillation, and blending.

Fragrance and cosmetics:
The essential oil is used in perfumery as a fragrance material. Its composition includes furanocoumarins; application in cosmetic formulations follows industry norms for sensitive accords and accords with IFRA Standards.

Properties relevant to use:
Achenes provide the dried spice and oil raw material. The essential oil’s suitability for flavor and fragrance applications derives from its content of furanocoumarins and related aromatic constituents, which influence aroma and stability.

Standards and regulation:
Flavor and fragrance uses of the essential oil are typically managed under IFRA Standards. The dried achenes, when used as a food ingredient, are subject to national food law and good manufacturing practice.

Sustainability and sourcing:
Visnaga daucoides is harvested from wild populations in parts of its Mediterranean range; sustainable collection is necessary to avoid depletion of local stands.

Synonyms Top

Scientific name Authority First published in
Visnaga vera Raf. New Fl. 4: 28 (1838)
Sium visnaga Stokes Bot. Mat. Med. 2: 106 (1812)
Ammi dilatatum St.-Lag. Ann. Soc. Bot. Lyon 7: 119 (1880)
Ammi visnaga (L.) Lam. Fl. Franç. 3: 462 (1779)
Ammi visnaga var. longibracteatum Zohary. Fl. Palaestina 2: 459 (1972)
Apium visnaga Crantz Cl. Umbell. Emend. : 104 (1767)
Carum visnaga Koso-Pol. Bull. Soc. Imp. Naturalistes Moscou , n.s., 29: 198 (1915 publ. 1916)
Daucus gingidium L. ex DC. Prodr. 4: 113 1830
Daucus laevis Salisb. Prodr. Stirp. Chap. Allerton : 162 (1796)
Daucus visnaga L. Sp. Pl. : 242 (1753)
Ammi visnaga var. hybernonis Sennen Diagn. Nouv. 117 1936
Ammi visnaga var. paui Sennen Diagn. Nouv. 116 1936
Selinum visnaga E.H.L.Krause Deutschl. Fl. Abbild. , ed. 2, 12: 44 (1904)

Common names Top

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Language Common/alternative name
Arabic صقلين
French visnaga vera
French daucus visnaga
French daucus laevis
French ammi visnaga var. longibracteatum
French ammi visnaga
French ammi dilatatum
French carum visnaga
French apium visnaga
French sium visnaga
French petit ammi
French herbe aux gencives
French herbe aux cure-dents
French fenouil annuel
French carotte cure-dent
French ammi visnage
French ammi cure-dents
Italian ammi visnaga
Swedish tandpetarsilja
Chinese 牙签芹
Chinese 阿米芹

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Sow seeds at 20°C, expecting germination within 3 months without further temperature treatment.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Africa
    • Macaronesia
      • Azores
      • Canary Islands
      • Madeira
    • Northeast Tropical Africa
      • Eritrea
      • Ethiopia
    • Northern Africa
      • Algeria
      • Egypt
      • Libya
      • Morocco
      • Tunisia
  • Asia-temperate
    • Caucasus
      • North Caucasus
      • Transcaucasus
    • China
      • China Southeast
    • Eastern Asia
      • Japan
    • Western Asia
      • Cyprus
      • East Aegean Islands
      • Iran
      • Iraq
      • Lebanon-Syria
      • Palestine
      • Turkey
  • Europe
    • Middle Europe
      • Belgium
      • Czechoslovakia
    • Northern Europe
      • Great Britain
    • Southeastern Europe
      • Albania
      • Greece
      • Italy
      • Sicilia
      • Turkey-in-Europe
    • Southwestern Europe
      • Baleares
      • Corse
      • France
      • Portugal
      • Sardegna
      • Spain
  • Northern America
    • Mexico
      • Mexico Southwest
    • Northeastern U.S.A.
      • Pennsylvania
    • Northwestern U.S.A.
      • Oregon
    • South-central U.S.A.
      • Texas
    • Southeastern U.S.A.
      • Alabama
      • Florida
      • North Carolina
    • Southwestern U.S.A.
      • California
  • Southern America
    • Brazil
      • Brazil South
    • Southern South America
      • Argentina Northeast
      • Argentina Northwest
      • Chile Central
      • Juan Fernández Islands
      • Uruguay
    • Western South America
      • Colombia
      • Peru

Links to other databases Top

Suggest others/fix!
Database ID/link to page
World Flora Online wfo-0000421889
Tropicos 1703282
INPN 129910
Flora of Italy 3587
KEW urn:lsid:ipni.org:names:849956-1
IPNI 849956-1
iNaturalist 806563
GBIF 5371753
USDA GRIN 466289
Wikipedia Visnaga_daucoides
Open Tree Of Life 642437

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
Title Authors Publication Released IDs
Khellin and Visnagin, Furanochromones from Ammi visnaga (L.) Lam., as Potential Bioherbicides. Travaini ML, Sosa GM, Ceccarelli EA, Walter H, Cantrell CL, Carrillo NJ, Dayan FE, Meepagala KM, Duke SO J Agric Food Chem 21-Dec-2016
doi:10.1021/ACS.JAFC.6B02462
PMID:27936681
Validated HPLC method for simultaneous estimation of khellol glucoside, khellin and visnagin in Ammi visnaga L. fruits and pharmaceutical preparations. Badr JM, Hadad GM, Nahriry K, Hassanean HA Nat Prod Res 01-Jan-2015
doi:10.1080/14786419.2014.945170
PMID:25111086
Influence of growing conditions on metabolite profile of Ammi visnaga umbels with special reference to bioactive furanochromones and pyranocoumarins. Sellami HK, Napolitano A, Masullo M, Smiti S, Piacente S, Pizza C Phytochemistry 01-Nov-2013
doi:10.1016/J.PHYTOCHEM.2013.08.001
PMID:23993295
Pharmacokinetic evaluation of visnagin and Ammi visnaga aqueous extract after oral administration in rats. Haug KG, Weber B, Hochhaus G, Butterweck V Planta Med 01-Nov-2012
doi:10.1055/S-0032-1315393
PMID:23096256
Prevention of renal crystal deposition by an extract of Ammi visnaga L. and its constituents khellin and visnagin in hyperoxaluric rats. Vanachayangkul P, Chow N, Khan SR, Butterweck V Urol Res 01-Jun-2011
PMCID:PMC3663934
doi:10.1007/S00240-010-0333-Y
PMID:21069311
An aqueous extract of Ammi visnaga fruits and its constituents khellin and visnagin prevent cell damage caused by oxalate in renal epithelial cells. Vanachayangkul P, Byer K, Khan S, Butterweck V Phytomedicine 01-Jul-2010
PMCID:PMC3618668
doi:10.1016/J.PHYMED.2009.10.011
PMID:20036111
<i>Ammi Visnaga</i>(L.) Lam.: Occurrence of Khellin and Visnagin in Primary Rib Channels and Endosperm, and Emptiness of Vittae, Revealed by U.V. Microscopy* G. G. Franchi, S. Ferri, L. Bovalini, P. Martelli Informa UK Limited 20-Nov-2007
doi:10.3109/13880208709060918
<i>Ammi visnaga</i>: Composition of the fatty acids present in the seed fat D. N. Grindley Wiley 01-Nov-2006
doi:10.1002/JSFA.2740010207
Analyse der Wirkstoffe aus Ammi visnaga L. G. Illing Wiley 15-Oct-2006
doi:10.1002/ARDP.19572900609
Visnagin: Biosynthesis and Isolation from Ammi visnagi Suspension Cultures B. Kaul, E. J. Staba American Association for the Advancement of Science (AAAS) 05-Oct-2006
doi:10.1126/SCIENCE.151.3707.184-B
Isolation and <sup>1</sup>H and <sup>13</sup>C NMR of Ammiol and Khellol Glucosides Larry W. Tjarks, Gayland F. Spencer, Eric P. Seest American Chemical Society (ACS) 17-Mar-2005
doi:10.1021/NP50063A033
Furocoumarins from the Fruit of Ammi visnaga Philip W. Le Quesne, Muu N. Do, Mohammad Ikram, M. Israrkkhan, I. Mir American Chemical Society (ACS) 17-Mar-2005
doi:10.1021/NP50039A030
Die Konstitution des Visamminols W. Bencze, Judith Eisenbeiss, H. Schmid Wiley 23-Dec-2004
doi:10.1002/HLCA.19560390337
The chemical investigations on the ripe fruits of Ammi visnaga (Lam.) Lamarck growing in Turkey. Günaydin K, Beyazit N Nat Prod Res 01-Apr-2004
doi:10.1080/14786410310001608091
PMID:14984092
Cytotoxic activity of five compounds isolated from Colombian plants. Cordero CP, Gómez-González S, León-Acosta CJ, Morantes-Medina SJ, Aristizabal FA Fitoterapia 01-Mar-2004
doi:10.1016/J.FITOTE.2003.12.017
PMID:15030931

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.
Name PubChem ID Canonical SMILES MW Found in Proof
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Chromones / Furanochromones
(2S)-4-hydroxy-2-(2-hydroxypropan-2-yl)-7-methyl-2,3-dihydrofuro[3,2-g]chromen-5-one 3083595 Click to see 276.28 unknown https://doi.org/10.1002/HLCA.19560390337
https://doi.org/10.1002/ARDP.19572900609
[(2S)-2-(2-hydroxypropan-2-yl)-4-methoxy-5-oxo-2,3-dihydrofuro[3,2-g]chromen-7-yl]methyl 2-methylbutanoate 73212329 Click to see CCC(C)C(=O)OCC1=CC(=O)C2=C(C3=C(C=C2O1)OC(C3)C(C)(C)O)OC 390.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2013.08.001
[(2S)-2-(2-hydroxypropan-2-yl)-4-methoxy-5-oxo-2,3-dihydrofuro[3,2-g]chromen-7-yl]methyl 3-methylbutanoate 73212328 Click to see 390.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2013.08.001
Ammiol 621572 Click to see COC1=C2C(=O)C=C(OC2=C(C3=C1C=CO3)OC)CO 276.24 unknown https://doi.org/10.1055/S-2006-960912
https://doi.org/10.1002/ARDP.19542870209
Ammiol glucoside 14377805 Click to see COC1=C2C(=O)C=C(OC2=C(C3=C1C=CO3)OC)COC4C(C(C(C(O4)CO)O)O)O 438.40 unknown https://doi.org/10.1021/NP50063A033
Khellin 3828 Click to see CC1=CC(=O)C2=C(C3=C(C(=C2O1)OC)OC=C3)OC 260.24 unknown https://doi.org/10.1016/S0141-0229(03)00180-7
https://doi.org/10.1002/JPS.2600810518
https://doi.org/10.1055/S-0028-1099861
https://doi.org/10.1002/ARDP.19572900609
https://doi.org/10.1055/S-2006-960912
https://doi.org/10.1002/JSFA.2740010207
https://doi.org/10.1080/14786410310001608091
https://doi.org/10.1016/S0021-9673(01)89202-5
https://doi.org/10.1055/S-2006-962061
https://doi.org/10.1016/S0021-9673(97)01173-4
https://doi.org/10.1002/HLCA.19560390337
https://doi.org/10.1055/S-2006-959426
https://doi.org/10.3109/13880208709060918
https://doi.org/10.1016/0378-8741(85)90088-1
https://doi.org/10.1016/J.FITOTE.2003.12.017
Khellinol 10167 Click to see 246.21 unknown https://doi.org/10.1002/ARDP.19572900609
https://doi.org/10.1055/S-2006-960912
https://doi.org/10.1002/HLCA.19560390337
Khellol 164613 Click to see 246.21 unknown https://doi.org/10.1055/S-2006-960912
https://doi.org/10.1002/ARDP.19572900609
Khelloside 441966 Click to see COC1=C2C=COC2=CC3=C1C(=O)C=C(O3)COC4C(C(C(C(O4)CO)O)O)O 408.40 unknown https://doi.org/10.1021/NP50063A033
https://doi.org/10.1111/J.2042-7158.1949.TB12460.X
https://doi.org/10.1002/ARDP.19572900609
Pimolin 100920750 Click to see 460.40 unknown https://doi.org/10.1055/S-2006-960912
Vernomycin B 28404 Click to see 408.40 unknown https://doi.org/10.1111/J.2042-7158.1949.TB12460.X
https://doi.org/10.1002/ARDP.19572900609
Visammiol 5315249 Click to see 276.28 unknown https://doi.org/10.1002/HLCA.19560390337
https://doi.org/10.1055/S-2006-960912
https://doi.org/10.1002/ARDP.19572900609
Visnagin 6716 Click to see CC1=CC(=O)C2=C(O1)C=C3C(=C2OC)C=CO3 230.22 unknown https://doi.org/10.1055/S-2006-960912
https://doi.org/10.1055/S-0032-1315393
https://doi.org/10.1126/SCIENCE.150.3704.1731
https://doi.org/10.1002/JPS.2600810518
https://doi.org/10.1080/14786419.2014.945170
https://doi.org/10.1016/S0141-0229(03)00180-7
https://doi.org/10.1055/S-2006-962061
https://doi.org/10.1016/S0021-9673(97)01173-4
https://doi.org/10.1002/HLCA.19560390337
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618668/
https://doi.org/10.1055/S-2006-959426
https://doi.org/10.1080/14786410310001608091
https://doi.org/10.1016/S0021-9673(01)89202-5
https://doi.org/10.1021/ACS.JAFC.6B02462
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663934/
https://doi.org/10.1126/SCIENCE.151.3707.184-B
https://doi.org/10.1016/0378-8741(85)90088-1
https://doi.org/10.3109/13880208709060918
> Phenylpropanoids and polyketides / Coumarins and derivatives / Furanocoumarins / Psoralens
Imperatorin 10212 Click to see 270.28 unknown https://doi.org/10.1021/NP50039A030
> Phenylpropanoids and polyketides / Coumarins and derivatives / Furanocoumarins / Psoralens / 8-methoxypsoralens
Methoxsalen 4114 Click to see COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2 216.19 unknown https://doi.org/10.1021/NP50039A030
> Phenylpropanoids and polyketides / Coumarins and derivatives / Pyranocoumarins / Angular pyranocoumarins
(10-Acetyloxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl) 2-methylbutanoate 10157 Click to see 388.40 unknown https://doi.org/10.1002/ARDP.19572900609
https://doi.org/10.1055/S-0028-1099861
(10-Acetyloxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl) 3-methylbut-2-enoate 10158 Click to see CC(=CC(=O)OC1C(C2=C(C=CC3=C2OC(=O)C=C3)OC1(C)C)OC(=O)C)C 386.40 unknown https://doi.org/10.1002/ARDP.19572900609
(9R,10S)-9,10-Dihydroxy-8,8-Dimethyl-9,10-Dihydropyrano(2,3-F)Chromen-2-One 9992853 Click to see 262.26 unknown https://doi.org/10.1002/ARDP.19572900609
Dihydrosamidin 442128 Click to see CC(C)CC(=O)OC1C(C2=C(C=CC3=C2OC(=O)C=C3)OC1(C)C)OC(=O)C 388.40 unknown https://doi.org/10.1002/ARDP.19572900609
Khellactone 253856 Click to see CC1(C(C(C2=C(O1)C=CC3=C2OC(=O)C=C3)O)O)C 262.26 unknown https://doi.org/10.1002/ARDP.19572900609
Khellactone, cis-(+)- 455821 Click to see 262.26 unknown https://doi.org/10.1002/ARDP.19572900609
rac Dihydro Samidin 2841560 Click to see 388.40 unknown https://doi.org/10.1002/ARDP.19572900609
Samidin 442150 Click to see 386.40 unknown https://doi.org/10.1002/ARDP.19572900609
Visnadine 442151 Click to see 388.40 unknown https://doi.org/10.1002/ARDP.19572900609
https://doi.org/10.1016/S0021-9673(97)01173-4
https://doi.org/10.1055/S-2006-959426
https://doi.org/10.1055/S-0028-1099861
> Phenylpropanoids and polyketides / Flavonoids / Flavones / Flavonols
Isorhamnetin 5281654 Click to see 316.26 unknown https://doi.org/10.1055/S-2006-960912
Rhamnazin 5320945 Click to see 330.29 unknown https://doi.org/10.1055/S-2006-960912

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