Hydrastis canadensis
Details Top
| Internal ID | UUID64404d1facd9f369157370 |
| Scientific name | Hydrastis canadensis |
| Authority | L. |
| First published in | Syst. Nat. ed. 10 , 2: 1088 (1759) |
General Uses Top
Suggest a correction!Colorants and tanning:
Roots and rhizomes provide a natural yellow dye used historically on wool and other protein fibers. Contemporary dyers report weak uptake on cotton. No tanning uses are documented.
Food and beverages (non-medicinal):
No documented non-medicinal food or beverage uses. Products such as teas and tinctures fall outside the scope of these sections.
Industrial and craft applications:
No documented industrial applications. All practical uses derive from the dye properties of the roots/rhizomes.
Common products:
Yellow dye prepared from dried, milled roots/rhizomes; sometimes marketed as “golden seal” dye.
Properties relevant to use:
The yellow color of the dye is attributed to alkaloids and other chromophores extracted with hot water or alcohol; modern craft references cite poor lightfastness in sunlight and variable staining on cellulose fibers.
Synonyms Top
| Scientific name | Authority | First published in |
|---|---|---|
| Warneria canadensis | Mill. | Fig. Pl. Gard. Dict. t. 285. 1759 |
| Hydrastis trifolia | Raf. | New Fl. 2: 34 (1837) |
Common names Top
Add a new one! Suggest a correction!| Language | Common/alternative name |
|---|---|
| English | goldenseal |
| Spanish | warnera tinctoria |
| Spanish | warnera diphylla |
| Arabic | ختم الذهب |
| Arabic | خاتم الذهب |
| Arabic | هيدراستوس |
| Arabic | خاتم ذهب |
| Arabic | جوذان مر |
| Bulgarian | канадски хидрастис |
| Catalan | hidrastis |
| Czech | vodilka |
| Czech | vodilka kanadská |
| German | hydrastidoideae |
| German | orangenwurzel |
| German | kanadische orangenwurzel |
| Persian | خوک طلایی |
| Finnish | hurmejuuri |
| French | hydraste du canada |
| Hungarian | kanadai aranygyökér |
| Japanese | ヒドラスチス・カナデンシス |
| Korean | 골든 실 |
| Korean | 히드라스티스 |
| Polish | gorzknik |
| Polish | gorzknik kanadyjski |
| Portuguese | hidraste |
| Quechua | uqu qura |
| Quechua | qurisaphi |
| Russian | Желтокорень |
| Slovak | vodilka kanadská |
| Turkish | altınmühür |
| Chinese | 北美黃蓮 |
| Chinese | 金印草 |
| Chinese | 金印草屬 |
| Chinese | 白毛莨屬 |
| Chinese | 白毛茛 |
Germination/Propagation Top
Suggest a correction or add new data!| Expose seeds to natural outdoor winter conditions for 3 months, then gradually increase light and temperature in the spring. |
| Pulpy Coat Inhibits Germination: Seeds with a pulpy or fleshy outer coat need to have this material removed by soaking and rinsing in clean water daily for about a week. The inhibitory substances in the pulp are thus washed away, and germination rates improve. |
| Sow seeds immediately as their viability decreases rapidly, or they best germinate when fresh. If stored, seeds might need temperature cycling and patience to germinate. |
Distribution (via POWO/KEW) Top
Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
-
Northern America click to expand
-
Eastern Canada
- Ontario
-
North-central U.S.A.
- Illinois
- Iowa
- Minnesota
- Missouri
- Wisconsin
-
Northeastern U.S.A.
- Connecticut
- Indiana
- Massachusetts
- Michigan
- New Jersey
- New York
- Ohio
- Pennsylvania
- Vermont
- West Virginia
-
Southeastern U.S.A.
- Alabama
- Arkansas
- Delaware
- Georgia
- Kentucky
- Maryland
- Mississippi
- North Carolina
- Tennessee
- Virginia
-
Eastern Canada
Links to other databases Top
Suggest others/fix!| Database | ID/link to page |
|---|---|
| World Flora Online | wfo-0001129287 |
| UNII | R763EBH88T |
| Flora of Alabama | 3050 |
| Canadensys | 8489 |
| USDA Plants | HYCA |
| Tropicos | 27100410 |
| KEW | urn:lsid:ipni.org:names:305699-2 |
| The Plant List | tro-27100410 |
| Missouri Botanical Garden | 286138 |
| Open Tree Of Life | 1072050 |
| Observations.org | 118848 |
| NCBI Taxonomy | 13569 |
| Nature Serve | 2.154701 |
| IUCN Red List | 44340011 |
| IPNI | 305699-2 |
| iNaturalist | 118768 |
| GBIF | 3033110 |
| Freebase | /m/01xwdr |
| WisFlora | 3893 |
| EPPO | HDRCA |
| EOL | 594852 |
| US Library of Congress | sh88022841 |
| USDA GRIN | 19478 |
| Wikipedia | Goldenseal |
| CMAUP | NPO1074 |
Genomes (via NCBI) Top
No reference genome is available on NCBI yet. We are constantly monitoring for new data.
Scientific Literature Top
Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
If you wish to see all the related articles click here.
Phytochemical Profile Top
Add a new one!
Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.
You can also contribute to this by clicking here.
| Name | PubChem ID | Canonical SMILES | MW | Found in | Proof |
|---|---|---|---|---|---|
| > Alkaloids and derivatives / Phthalide isoquinolines | |||||
| (-)-Hydrastine | 197835 | Click to see | 383.40 | unknown |
https://doi.org/10.1081/JLC-100105950 https://doi.org/10.1002/ARDP.19172550802 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142294/ https://doi.org/10.1093/JAOAC/86.3.476 https://doi.org/10.1002/(SICI)1099-1573(1998)12:1+ https://doi.org/10.1055/S-2003-37039 https://doi.org/10.1016/J.FITOTE.2010.06.006 https://doi.org/10.1002/ARDP.18982360906 https://doi.org/10.1055/S-2001-16493 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894911/ https://doi.org/10.1002/JPS.1035 https://doi.org/10.1016/S0021-9673(97)00804-2 https://doi.org/10.1002/1099-1573(200012)14:8<612::AID-PTR677>3.0.CO;2-T https://doi.org/10.1081/JLC-100105948 https://doi.org/10.2307/4117899 https://doi.org/10.1080/13880200390500768 https://doi.org/10.1021/NP9701889 https://doi.org/10.1081/JLC-100000329 https://doi.org/10.1016/S0367-326X(99)00162-8 https://doi.org/10.1002/PTR.1108 https://doi.org/10.1021/NP049868J https://doi.org/10.1055/S-2003-41115 https://doi.org/10.1081/JLC-100108744 |
| (3S)-6,7-dimethoxy-3-(6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-2-benzofuran-1-one | 371942 | Click to see CN1CCC2=CC3=C(C=C2C1C4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OCO3 | 383.40 | unknown | https://doi.org/10.1021/NP9701889 |
| 6,7-Dimethoxy-3-(6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-2-benzofuran-1(3H)-one | 1309 | Click to see CN1CCC2=CC3=C(C=C2C1C4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OCO3 | 383.40 | unknown |
https://doi.org/10.1081/JLC-100105950 https://doi.org/10.1002/ARDP.19172550802 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142294/ https://doi.org/10.1093/JAOAC/86.3.476 https://doi.org/10.1002/(SICI)1099-1573(1998)12:1+ https://doi.org/10.1055/S-2003-37039 https://doi.org/10.1016/J.FITOTE.2010.06.006 https://doi.org/10.1002/ARDP.18982360906 https://doi.org/10.1055/S-2001-16493 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894911/ https://doi.org/10.1016/S0021-9673(97)00804-2 https://doi.org/10.1002/1099-1573(200012)14:8<612::AID-PTR677>3.0.CO;2-T https://doi.org/10.1081/JLC-100105948 https://doi.org/10.1080/13880200390500768 https://doi.org/10.1021/NP9701889 https://doi.org/10.1081/JLC-100000329 https://doi.org/10.1016/S0367-326X(99)00162-8 https://doi.org/10.1002/PTR.1108 https://doi.org/10.1055/S-2003-41115 |
| > Alkaloids and derivatives / Protoberberine alkaloids and derivatives | |||||
| (-)-Tetrahydrocolumbamine | 440229 | Click to see | 341.40 | unknown | https://doi.org/10.1055/S-2003-41115 |
| (14S)-16,17-dimethoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(21),2,4(8),9,15(20),16,18-heptaen-14-ol | 162905761 | Click to see | 353.40 | unknown | https://doi.org/10.1002/ARDP.19172550802 |
| (R)-Canadine | 443422 | Click to see COC1=C(C2=C(CC3C4=CC5=C(C=C4CCN3C2)OCO5)C=C1)OC | 339.40 | unknown | https://doi.org/10.1021/NP9701889 |
| (S)-Canadine | 21171 | Click to see | 339.40 | unknown |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142294/ https://doi.org/10.1055/S-2001-16493 https://doi.org/10.1002/ARDP.18942320111 https://doi.org/10.1021/NP9701889 |
| 10-Hydroxy-9-methoxy-5,6,13,13a-tetrahydro-[1,3]dioxolo[4,5-g] isoquino[3,2-a]isoquinolin-8-one | 100916731 | Click to see | 339.30 | unknown | https://doi.org/10.1021/NP9701889 |
| 16,17-Dimethoxy-6-tritio-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene | 10246509 | Click to see | 338.40 | unknown | via CMAUP database |
| 8-Oxocanadine | 470418 | Click to see COC1=C(C2=C(CC3C4=CC5=C(C=C4CCN3C2=O)OCO5)C=C1)OC | 353.40 | unknown | https://doi.org/10.1021/NP9701889 |
| 8-Oxotetrahydrothalifendine | 470416 | Click to see | 339.30 | unknown | https://doi.org/10.1021/NP9701889 |
| Acetyl 8-oxotetrahydrothalifendine | 470417 | Click to see | 381.40 | unknown | https://doi.org/10.1021/NP9701889 |
| Berberastine | 442180 | Click to see COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4C(C3)O)OCO5)OC | 352.40 | unknown | via CMAUP database |
| Berberine | 2353 | Click to see | 336.40 | unknown |
https://doi.org/10.1002/(SICI)1099-1573(199812)12:8<589::AID-PTR347>3.0.CO;2-I https://doi.org/10.1081/JLC-100000329 https://doi.org/10.1016/S0367-326X(99)00162-8 https://doi.org/10.1081/JLC-100105950 https://doi.org/10.1081/JLC-100105948 https://doi.org/10.1016/S0021-9673(97)00804-2 https://doi.org/10.1211/0022357021778510 https://doi.org/10.1002/(SICI)1099-1573(1998)12:1+ https://doi.org/10.1002/JPS.1035 https://doi.org/10.1021/NP9701889 https://doi.org/10.1055/S-2001-16493 https://doi.org/10.1093/JAOAC/86.3.476 https://doi.org/10.1002/PTR.1108 https://doi.org/10.1055/S-2003-41115 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894911/ https://doi.org/10.1081/JLC-100108744 https://doi.org/10.1021/NP049868J https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142294/ |
| Berberinol | 24974 | Click to see | 353.40 | unknown | https://doi.org/10.1002/ARDP.19172550802 |
| Canadine | 34458 | Click to see COC1=C(C2=C(CC3C4=CC5=C(C=C4CCN3C2)OCO5)C=C1)OC | 339.40 | unknown |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142294/ https://doi.org/10.1002/(SICI)1099-1573(1998)12:1+ https://doi.org/10.1081/JLC-100105950 https://doi.org/10.1081/JLC-100000329 https://doi.org/10.1055/S-2001-16493 https://doi.org/10.1055/S-2003-41115 https://doi.org/10.1002/ARDP.18942320111 https://doi.org/10.1016/S0021-9673(97)00804-2 https://doi.org/10.1021/NP049868J https://doi.org/10.1093/JAOAC/86.3.476 https://doi.org/10.1021/NP9701889 |
| Palmatine | 19009 | Click to see | 352.40 | unknown |
https://doi.org/10.1093/JAOAC/86.3.476 https://doi.org/10.1021/NP049868J https://doi.org/10.1081/JLC-100000329 |
| > Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Taxanes and derivatives | |||||
| [2,8,9,16-Tetraacetyloxy-5-hydroxy-3-(2-hydroxypropan-2-yl)-6,10-dimethyl-14-oxatetracyclo[8.6.0.03,7.013,16]hexadec-6-en-11-yl] acetate | 73192583 | Click to see CC1=C2C(C(C3(C(CC4C(C3C(C2(CC1O)C(C)(C)O)OC(=O)C)(CO4)OC(=O)C)OC(=O)C)C)OC(=O)C)OC(=O)C | 610.60 | unknown | https://doi.org/10.1021/NP9701889 |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives | |||||
| (2S,3R,4S,5S,6R)-2-[[(3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol | 12309073 | Click to see | 576.80 | unknown | via CMAUP database |
| beta-Sitosterol 3-O-beta-D-galactopyranoside | 296119 | Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C | 576.80 | unknown | https://doi.org/10.1055/S-2003-41115 |
| Sitogluside | 5742590 | Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C | 576.80 | unknown | https://doi.org/10.1055/S-2003-41115 |
| > Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Cyclitols and derivatives / Quinic acids and derivatives | |||||
| butyl (1R,3R,4S,5R)-1,3,4-trihydroxy-5-[(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]cyclohexane-1-carboxylate | 100916732 | Click to see | 408.40 | unknown | https://doi.org/10.1021/NP9701889 |
| Butyl 1,3,4-trihydroxy-5-[3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyloxy]cyclohexane-1-carboxylate | 53436162 | Click to see CCCCOC(=O)C1(CC(C(C(C1)OC(=O)C=CC2=CC(=C(C=C2)O)OC)O)O)O | 424.40 | unknown | https://doi.org/10.1021/NP9701889 |
| Butyl 1,3,5-trihydroxy-4-[3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyloxy]cyclohexane-1-carboxylate | 470422 | Click to see | 424.40 | unknown | https://doi.org/10.1021/NP9701889 |
| Chlorogenic Acid | 1794427 | Click to see C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O | 354.31 | unknown | https://doi.org/10.1021/NP049868J |
| Hycandinic acid ester 2 | 100916733 | Click to see CCCCOC(=O)C1(CC(C(C(C1)O)C(=O)C=CC2=CC(=C(C=C2)O)OC)O)O | 408.40 | unknown | https://doi.org/10.1021/NP9701889 |
| Hycandinic acid ester-1 | 6440343 | Click to see CCCCOC(=O)C1(CC(C(C(C1)OC(=O)C=CC2=CC(=C(C=C2)O)OC)O)O)O | 424.40 | unknown | https://doi.org/10.1021/NP9701889 |
| Neochlorogenic acid | 5280633 | Click to see C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O | 354.31 | unknown | https://doi.org/10.1021/NP049868J |
| > Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Aldehydes / Aryl-aldehydes | |||||
| 5-Hydroxymethylfurfural | 237332 | Click to see C1=C(OC(=C1)C=O)CO | 126.11 | unknown | https://doi.org/10.1002/1099-1573(200012)14:8<612::AID-PTR677>3.0.CO;2-T |
| > Organoheterocyclic compounds / Indoles and derivatives / Indoles / 3-alkylindoles | |||||
| 2-(((6-bromo-1H-indol-3-yl)methyl)thio)ethanamine | 23425272 | Click to see C1=CC2=C(C=C1Br)NC=C2CSCCN | 285.21 | unknown | via CMAUP database |
| > Organoheterocyclic compounds / Isoquinolines and derivatives / Benzylisoquinolines | |||||
| 2,3-dimethoxy-6-[(6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl]benzaldehyde | 321459 | Click to see | 369.40 | unknown |
https://doi.org/10.1002/(SICI)1099-1573(1998)12:1+ https://doi.org/10.1016/S0031-9422(00)91388-8 https://doi.org/10.1055/S-2003-41115 https://doi.org/10.1081/JLC-100105950 https://doi.org/10.1055/S-2001-16493 |
| 2,3-dimethoxy-6-[(6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl]benzoic acid | 163000391 | Click to see | 385.40 | unknown | https://doi.org/10.1055/S-2006-957649 |
| 2,3-dimethoxy-6-[[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]methyl]benzaldehyde | 14527257 | Click to see | 369.40 | unknown | https://doi.org/10.1055/S-2001-16493 |
| 2,3-dimethoxy-6-[[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]methyl]benzoic acid | 163000392 | Click to see CN1CCC2=CC3=C(C=C2C1CC4=C(C(=C(C=C4)OC)OC)C(=O)O)OCO3 | 385.40 | unknown | https://doi.org/10.1055/S-2006-957649 |
| Canadaline | 9864120 | Click to see | 369.40 | unknown |
https://doi.org/10.1002/(SICI)1099-1573(1998)12:1+ https://doi.org/10.1016/S0031-9422(00)91388-8 https://doi.org/10.1055/S-2003-41115 https://doi.org/10.1081/JLC-100105950 https://doi.org/10.1055/S-2001-16493 |
| > Organoheterocyclic compounds / Tetrahydroisoquinolines | |||||
| Hydrastinine | 3638 | Click to see CN1CCC2=CC3=C(C=C2C1O)OCO3 | 207.23 | unknown |
https://doi.org/10.1211/0022357021778510 https://doi.org/10.1016/S0367-326X(99)00162-8 https://doi.org/10.1021/NP049868J https://doi.org/10.1016/S0021-9673(97)00804-2 https://doi.org/10.1081/JLC-100000329 |
| > Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives | |||||
| Caftaric Acid | 6440397 | Click to see | 312.23 | unknown | https://doi.org/10.1081/JLC-100108744 |
| > Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids | |||||
| 6-Desmethylsideroxylin | 56665369 | Click to see CC1=C(C=C(C2=C1OC(=CC2=O)C3=CC=C(C=C3)O)O)OC | 298.29 | unknown | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142294/ |
| 6,8-di-C-methylluteolin 7-methyl ether | 10065066 | Click to see | 328.30 | unknown | via CMAUP database |
| 8-Demethylsideroxylin | 44258359 | Click to see | 298.29 | unknown | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142294/ |
| Sideroxylin | 3083788 | Click to see | 312.30 | unknown | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142294/ |
Collections Top
| In private collections | 0 |
| In public collections | 0 |