Aconitum sajanense

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Common products:
Alkaloid extracts from the aerial parts and roots of Aconitum sajanense are employed as reference standards in analytical chemistry and toxicology research. Phytochemical investigations have identified the C₁₉‑diterpenoid alkaloids aconitine, mesaconitine, and hypaconitine, and these compounds are supplied to laboratories for calibration of chromatographic and mass‑spectrometric methods and for neurotoxicity assays.

Properties relevant to use:
The principal alkaloids in A. sajanense are C₁₉‑diterpenoid alkaloids containing a tertiary amine and multiple ester functionalities, which confer high lipophilicity (log P > 2) and potent neurotoxic activity. These physicochemical characteristics make the extracts suitable as stable reference materials for quantitative analyses and for mechanistic studies of ion‑channel modulation.

Standards and regulation:
In the Russian Federation, A. sajanense is listed as a poisonous species under Federal Law No. 324‑FZ on the safety of agricultural products, and its collection from wild habitats is subject to permits issued by regional environmental authorities. The species is included in the Red Book of the Republic of Buryatia and the Russian Federation as a species of conservation concern; however, it is not presently listed under the Convention on International Trade in Endangered Species (CITES).

Sustainability and sourcing:
A. sajanense is endemic to high‑altitude alpine meadows of the Sayan Mountains, where its populations are small and fragmented. Because of its restricted distribution, wild harvesting is tightly regulated, and conservation programs promote ex situ propagation in botanical gardens and research institutions to supply the limited quantities of alkaloid extracts needed for scientific work while protecting natural populations. The conservation status is recorded as “Vulnerable” in national Red List assessments.

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