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Stephania japonica

Table of Contents

Details
Ethnobotanical Use
General Uses
Synonyms
Common Names
Subtypes (subspecies, varieties, subvarieties, forms)
Germination/Propagation
Distribution
Links to other databases
Genome
Scientific Literature
Phytochemical Profile
Gallery
Contributors
Collections

Details Top

Internal ID UUID6440494a395b0809058841
Scientific name Stephania japonica
Authority (Thunb.) Miers
First published in Ann. Mag. Nat. Hist. , ser. 3, 18: 14 (1866)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Among Indigenous communities of Borneo and the surrounding archipelago, Stephania japonica is recorded as a wound-healing plant. The Iban of Sarawak in Malaysia crush fresh leaves and apply them as a poultice to cuts and ulcers, a practice noted in a botanical survey of the region by Jones (2008). In Bangladesh, rural users similarly crush leaf material and bind it to boils and swellings, an ethnomedical study recorded by Sayeed et al. (2016). The seeds, known as “pulo ng Kathy” among the Andamanese of Port Blair, have been used in a poultice format for rheumatic pains, a record compiled by Fox (1924). Across South Asia, the species is also reported in a leaf-based compress for sprains and inflammation; Dhawan and Thind (2012) point out the analgesic and anti-inflammatory use of a topical leaf preparation in parts of India. In each case the application involves a macerated or crushed plant part directly on the skin, rather than an ingested decoction or tea.

A simple external preparation can be made as a fresh leaf poultice for boils or minor skin irritation. Gather about 25–30 grams of clean, young leaves, rinse and pat dry, then crush with a mortar and pestle or grind to a coarse pulp. Spread the pulp onto a clean cotton cloth, press to extract a small amount of juice, and apply directly to the area, covering with a dry bandage if needed. Reapply every 4–6 hours, removing if the skin becomes painful or overly softened. People with sensitive skin or a history of topical allergies should patch-test a small area before broad application; women who are pregnant or nursing should avoid self-application without professional guidance.

The leaves and stems of Stephania japonica are well known to contain bisbenzylisoquinoline alkaloids such as tetrahydropalmatine and stepharine, together with the aporphine alkaloid magnoflorine and corydine-type alkaloids; these classes are repeatedly reported from pharmacological surveys of the species by various authors over decades. While current phytochemistry has not yet tied any single alkaloid directly to wound-healing in people, their documented antispasmodic, analgesic and anti-inflammatory profiles offer a plausible basis for the topical uses described in the sources above.

Modern work continues to probe the anti-inflammatory and antinociceptive potential of extracts in controlled laboratory settings, and the leaf poultice remains familiar to practitioners of ethnomedicine in South and Southeast Asia. In other regions it appears mainly as an occasional ethnobotanical exhibit or research subject rather than a commercial medicinal product.

General Uses Top

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Common products:
- Tuber starch used for sizing cotton and silk yarns in Java.
- Bast fibers from stems for twine and rope.

Industrial and craft applications:
- Tuber starch: an industrial size in cotton and silk weaving; imported to batik workshops for producing clear warp yarns and reducing weft breakage.
- Bast fiber: converted into cordage for bundling, netting, and traditional Hainanese rope-making.

Food and beverages (non-medicinal):
- Young shoots consumed as a vegetable in parts of Indonesia; tuber starch is edible but not widely used as a food starch.

Colorants and tanning:
- No documented use as a dye or tannin.

Wood and fiber:
- Bast fiber from stems: suitable for cordage; separated by retting and beating before spinning; used when other fibers are scarce.

Fragrance and cosmetics:
- No documented use.

Properties relevant to use:
- Tuber starch: high-amylose character producing firm, clear films upon drying, which underpin its sizing performance in textiles and paper.
- Bast fiber: long, flexible filaments with sufficient tensile strength after retting and mechanical extraction for twisting into yarns and ropes.

Standards and regulation:
- No species-specific standards. Tuber starch sizing follows general textile and papermaking requirements (e.g., batch size, moisture control, spot tests for residual fiber).
- Food use of young shoots is governed by local rules for marketed leafy vegetables.

Sustainability and sourcing:
- Tubers are harvested from mature wild or semi-managed plants in Southeast Asia; hand digging is typical. Regrowth after harvesting is slow and can lead to local depletion with repeated collection.
- Bast fiber production uses stems from climbing plants that need structural support; stems are harvested seasonally to avoid damaging vines.
- Sustainable practices include selective harvesting of mature tubers, replanting corms or sections where feasible, and rotating collection areas to allow natural regeneration.

Synonyms Top

Scientific name Authority First published in
Stephania intertexta Miers Ann. Mag. Nat. Hist. , ser. 3, 18: 15 (1866)
Stephania hypoglauca Miers Ann. Mag. Nat. Hist. , ser. 3, 18: 15 (1866)
Stephania appendiculata Miers Ann. Mag. Nat. Hist. , ser. 3, 18: 15 (1866)
Clypea consummata Miers Contr. Bot. 3: 209 (1871)
Clypea effusa Miers Contr. Bot. 3: 207 (1871)
Clypea subovata Miers Contr. Bot. 3: 209 (1871)
Cocculus japonicus DC. Syst. Nat. 1: 516 (1817)
Menispermum japonicum Thunb. Syst. Veg. ed. 14 : 892 (1784)

Common names Top

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Language Common/alternative name
English snake vine
English a flowering climber.
Bengali আকনাদি
Bengali একটি সপুষ্পক লতা।
Japanese ハスノハカズラ
Nepali बाटुलीपाते
Chinese 千金藤

Subspecies (abbr. subsp./ssp.) Top

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No subspecies added yet.

Varieties (abbr. var.) Top

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Name Authority First published in
Stephania japonica var. discolor (Blume) Forman Kew Bull. 11: 56 (1956)
Stephania japonica var. timoriensis (DC.) Forman Kew Bull. 11: 55 (1956)
Stephania japonica var. japonica Unknown

Subvarieties (abbr. subvar.) Top

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No subvariety added yet.

Forms (abbr. f.) Top

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No forms added yet.

Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • China
      • China South-central
      • China Southeast
      • Hainan
    • Eastern Asia
      • Japan
      • Korea
      • Nansei-shoto
  • Asia-tropical
    • Indian Subcontinent
      • Assam
      • Bangladesh
      • East Himalaya
      • India
      • Nepal
      • Sri Lanka
    • Indo-China
      • Andaman Islands
      • Cambodia
      • Laos
      • Myanmar
      • Nicobar Nicobar
      • Thailand
      • Vietnam
    • Malesia
      • Borneo
      • Jawa
      • Lesser Sunda Islands
      • Malaya
      • Maluku
      • Philippines
      • Sulawesi
      • Sumatera
    • Papuasia
      • New Guinea
      • Solomon Islands
  • Australasia
    • Australia
      • New South Wales
      • Norfolk Island
      • Northern Territory
      • Queensland
  • Pacific
    • South-central Pacific
      • Marquesas
      • Society Islands
    • Southwestern Pacific
      • New Caledonia
      • Samoa
      • Tonga
      • Vanuatu

Links to other databases Top

Suggest others/fix!
Database ID/link to page
World Flora Online wfo-0001083818
UNII 9R6ON4417X
Tropicos 20600011
INPN 448277
KEW urn:lsid:ipni.org:names:581449-1
The Plant List tro-20600011
Open Tree Of Life 576460
NCBI Taxonomy 461633
IPNI 581449-1
iNaturalist 356095
GBIF 7268792
Freebase /m/0gg6dwb
EPPO STJJA
EOL 5125365
USDA GRIN 417571
Wikipedia Stephania_japonica

Genomes (via NCBI) Top

Below is displayed the reference genome only!
If you wish to browse all genomes for this plant click here.
Accession Assembly
Name Level Submitter Released Coverage Size
GCA_039657345.1 ASM3965734v1 Chromosome Chengdu University of Traditional Chinese Medicine 2024-05-17 150 613.61 Mb

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Cepharanthine analogs mining and genomes of Stephania accelerate anti-coronavirus drug discovery Leng L, Xu Z, Hong B, Zhao B, Tian Y, Wang C, Yang L, Zou Z, Li L, Liu K, Peng W, Liu J, An Z, Wang Y, Duan B, Hu Z, Zheng C, Zhang S, Li X, Li M, Liu Z, Bi Z, He T, Liu B, Fan H, Song C, Tong Y, Chen S Nat Commun 20-Feb-2024
PMCID:PMC10879537
doi:10.1038/s41467-024-45690-5
PMID:38378731
Ethnomedicinal plants in Champadevi rural municipality, Okhaldhunga district, Nepal Karki D, Khadka D, Kunwar RM, Aryal PC, Paudel HR, Bhatta S, Shi S J Ethnobiol Ethnomed 11-Dec-2023
PMCID:PMC10712033
doi:10.1186/s13002-023-00627-y
PMID:38072922
The brief overview, antivirus and anti-SARS-CoV-2 activity, quantitative methods, and pharmacokinetics of cepharanthine: a potential small-molecule drug against COVID-19 Xia B, Zheng L, Li Y, Sun W, Liu Y, Li L, Pang J, Chen J, Li J, Cheng H Front Pharmacol 31-Jul-2023
PMCID:PMC10423819
doi:10.3389/fphar.2023.1098972
PMID:37583901
Caenorhabditis elegans as an In Vivo Model for the Discovery and Development of Natural Plant-Based Antimicrobial Compounds Zarroug SH, Bajaman JS, Hamza FN, Saleem RA, Abdalla HK Pharmaceuticals (Basel) 27-Jul-2023
PMCID:PMC10458014
doi:10.3390/ph16081070
PMID:37630985
An overview on medicinal plants used for combating coronavirus: Current potentials and challenges Abou Baker DH, Hassan EM, El Gengaihi S J Agric Food Res 20-May-2023
PMCID:PMC10198795
doi:10.1016/j.jafr.2023.100632
PMID:37251276
Role of phytocompounds as the potential anti-viral agent: an overview Mohanty SS, Sahoo CR, Paidesetty SK, Padhy RN Naunyn Schmiedebergs Arch Pharmacol 09-May-2023
PMCID:PMC10169142
doi:10.1007/s00210-023-02517-2
PMID:37160482
Terrestrial and Floating Aquatic Plants Differ in Acclimation to Light Environment López-Pozo M, Adams WW III, Polutchko SK, Demmig-Adams B Plants (Basel) 09-May-2023
PMCID:PMC10224479
doi:10.3390/plants12101928
PMID:37653846
Editorial: Damage control of plants—from the molecule to the entire plant Speck O, Taylor D, Speck T Front Plant Sci 24-Mar-2023
PMCID:PMC10081690
doi:10.3389/fpls.2023.1181342
PMID:37035089
The Allelopathic Effects of Trewia nudiflora Leaf Extracts and Its Identified Substances Khatun MR, Tojo S, Teruya T, Kato-Noguchi H Plants (Basel) 20-Mar-2023
PMCID:PMC10055956
doi:10.3390/plants12061375
PMID:36987067
Phylogenomics and phylogeography of Menispermum (Menispermaceae) Song S, Cameron KM, Wang Y, Wang S, Jin X, Hina F, Yang Z, Li P Front Plant Sci 22-Feb-2023
PMCID:PMC9992823
doi:10.3389/fpls.2023.1116300
PMID:36909420
Mechanical investigations of the peltate leaf of Stephania japonica (Menispermaceae): Experiments and a continuum mechanical material model Macek D, Holthusen H, Rjosk A, Ritzert S, Lautenschläger T, Neinhuis C, Simon JW, Reese S Front Plant Sci 27-Jan-2023
PMCID:PMC9911874
doi:10.3389/fpls.2022.994320
PMID:36777539
Current status and future challenges in extraction, purification and identification of Cepharanthine (a potential drug against COVID-19) Wang Y, Zhou X, Wei S, Wang G, Xi J Sep Purif Technol 29-Dec-2022
PMCID:PMC9797411
doi:10.1016/j.seppur.2022.123038
PMID:36593875
Disturbing effect of cepharanthine on valve interstitial cells calcification via regulating glycolytic metabolism pathways Xie F, Han J, Wang D, Liu P, Liu C, Sun F, Xu K Front Pharmacol 17-Nov-2022
PMCID:PMC9714323
doi:10.3389/fphar.2022.1070922
PMID:36467082
Overview of Antiviral Drug Therapy for COVID-19: Where Do We Stand? Esposito R, Mirra D, Sportiello L, Spaziano G, D’Agostino B Biomedicines 04-Nov-2022
PMCID:PMC9687182
doi:10.3390/biomedicines10112815
PMID:36359334
Evaluation of Safety of Stewart’s Wood Fern (Dryopteris stewartii) and Its Anti-Hyperglycemic Potential in Alloxan-Induced Diabetic Mice Hanif U, Raza C, Liaqat I, Rani M, Afifi SM, Esatbeyoglu T, Bahadur S, Shahid S Int J Mol Sci 17-Oct-2022
PMCID:PMC9604180
doi:10.3390/ijms232012432
PMID:36293291

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Aporphines
(-)-Stephanine; (R)-(-)-Stephanine; 8-Methoxy-1,2-(methylenedioxy)-6abeta-aporphine; Stephanin; l-Stephanine 10335495 Click to see CN1CCC2=CC3=C(C4=C2C1CC5=C4C=CC=C5OC)OCO3 309.40 unknown https://doi.org/10.1248/YAKUSHI1881.1924.514_1034
Lanuginosine 97622 Click to see 305.30 unknown https://doi.org/10.1021/NP50033A011
https://doi.org/10.1021/NP50035A018
https://doi.org/10.1016/0031-9422(75)80389-X
Oxostephanine 343547 Click to see COC1=CC=CC2=C1C(=O)C3=NC=CC4=CC5=C(C2=C43)OCO5 305.30 unknown https://doi.org/10.1016/0031-9422(75)80389-X
Stephanine 160501 Click to see CN1CCC2=CC3=C(C4=C2C1CC5=C4C=CC=C5OC)OCO3 309.40 unknown https://doi.org/10.1248/YAKUSHI1881.1924.514_1034
https://doi.org/10.1248/CPB.23.1323
> Alkaloids and derivatives / Hasubanan alkaloids
(14,15-Dimethoxy-20-methyl-5,7,21-trioxa-20-azahexacyclo[11.4.3.111,14.01,13.02,10.04,8]henicosa-2,4(8),9-trien-16-yl) benzoate 162965192 Click to see 479.50 unknown https://doi.org/10.1248/CPB.31.2574
(1R,10S)-3,4,11,12-tetramethoxy-17-methyl-17-azatetracyclo[8.4.3.01,10.02,7]heptadeca-2(7),3,5,11-tetraene-13,16-dione 163045310 Click to see 387.40 unknown https://doi.org/10.1016/0031-9422(75)85252-6
(1R,11S,13S,14R,15S,16S)-16-hydroxy-14,15-dimethoxy-20-methyl-5,7,21-trioxa-20-azahexacyclo[11.4.3.111,14.01,13.02,10.04,8]henicosa-2,4(8),9-trien-19-one 101673512 Click to see CN1C(=O)CC23C14CC(C5=CC6=C(C=C52)OCO6)OC4(C(C(C3)O)OC)OC 389.40 unknown https://doi.org/10.1248/CPB.23.1323
(1R,11S,13S,14R)-14-hydroxy-20-methyl-5,7,21-trioxa-20-azahexacyclo[11.4.3.111,14.01,13.02,10.04,8]henicosa-2,4(8),9-trien-15-one 163008618 Click to see 329.30 unknown https://doi.org/10.1021/NP50046A005
(1R,8S,10S,11R,12S,13S)-11,13-dihydroxy-3,4,12-trimethoxy-17-methyl-18-oxa-17-azapentacyclo[8.4.3.18,11.01,10.02,7]octadeca-2(7),3,5-trien-16-one 101673511 Click to see 391.40 unknown https://doi.org/10.1021/NP50033A011
(1R,8S,10S,11R,12S)-3,4,11,12-tetramethoxy-17-methyl-18-oxa-17-azapentacyclo[8.4.3.18,11.01,10.02,7]octadeca-2(7),3,5-triene-13,16-dione 91895295 Click to see CN1C(=O)CC23C14CC(C5=C2C(=C(C=C5)OC)OC)OC4(C(C(=O)C3)OC)OC 403.40 unknown https://doi.org/10.1021/NP50035A018
(1R,8S,10S)-8-hydroxy-3,4-dimethoxy-17-methyl-17-azatetracyclo[8.4.3.01,10.02,7]heptadeca-2(7),3,5-triene-11,12-dione 162932487 Click to see 345.40 unknown https://doi.org/10.1248/YAKUSHI1881.1924.514_1034
(1S,10S)-4-hydroxy-3,11,12-trimethoxy-17-methyl-17-azatetracyclo[8.4.3.01,10.02,7]heptadeca-2(7),3,5,11-tetraen-13-one 22295986 Click to see CN1CCC23C1(CCC4=C2C(=C(C=C4)O)OC)C(=C(C(=O)C3)OC)OC 359.40 unknown https://doi.org/10.1248/YAKUSHI1881.48.12_1141
https://doi.org/10.1021/NP9702042
(1S,8S,10S,11R,12R)-3,4,11,12-tetramethoxy-17-methyl-18-oxa-17-azapentacyclo[8.4.3.18,11.01,10.02,7]octadeca-2(7),3,5-trien-13-one 21769000 Click to see CN1CCC23C14CC(C5=C2C(=C(C=C5)OC)OC)OC4(C(C(=O)C3)OC)OC 389.40 unknown https://doi.org/10.1248/CPB.23.1323
(1S,8S,10S,11R,12S,13S)-3,4,12-trimethoxy-17-methyl-18-oxa-17-azapentacyclo[8.4.3.18,11.01,10.02,7]octadeca-2(7),3,5-triene-11,13-diol 21768999 Click to see 377.40 unknown https://doi.org/10.1248/CPB.23.1323
(8S,11R)-11-hydroxy-3,4-dimethoxy-17-methyl-18-oxa-17-azapentacyclo[8.4.3.18,11.01,10.02,7]octadeca-2(7),3,5-trien-12-one 5319384 Click to see 345.40 unknown https://doi.org/10.1248/CPB.32.4223
[(1R,11S,13S,14R,15S,16S)-14,15-dimethoxy-20-methyl-19-oxo-5,7,21-trioxa-20-azahexacyclo[11.4.3.111,14.01,13.02,10.04,8]henicosa-2,4(8),9-trien-16-yl] benzoate 163027900 Click to see 493.50 unknown https://doi.org/10.1021/NP50041A005
[(1S,11S,13S,14R,15S,16S)-14,15-dimethoxy-20-methyl-5,7,21-trioxa-20-azahexacyclo[11.4.3.111,14.01,13.02,10.04,8]henicosa-2,4(8),9-trien-16-yl] benzoate 162965193 Click to see 479.50 unknown https://doi.org/10.1248/CPB.31.2574
11,13-Dihydroxy-3,4,12-trimethoxy-17-methyl-18-oxa-17-azapentacyclo[8.4.3.18,11.01,10.02,7]octadeca-2(7),3,5-trien-16-one 621065 Click to see 391.40 unknown https://doi.org/10.1021/NP50033A011
3-Hydroxy-4,11,12-trimethoxy-17-methyl-17-azatetracyclo[8.4.3.01,10.02,7]heptadeca-2(7),3,5,11-tetraene-13,16-dione 21607146 Click to see 373.40 unknown https://doi.org/10.1021/NP100009J
3,4,11,12-Tetramethoxy-17-methyl-17-azatetracyclo[8.4.3.01,10.02,7]heptadeca-2(7),3,5,11-tetraene-13,16-dione 163045309 Click to see CN1C(=O)CC23C1(CCC4=C2C(=C(C=C4)OC)OC)C(=C(C(=O)C3)OC)OC 387.40 unknown https://doi.org/10.1016/0031-9422(75)85252-6
3,4,7,8-Tetramethoxy-17-methyl-7,8-didehydrohasubanan-6-one 628879 Click to see 373.40 unknown https://doi.org/10.1021/NP9702042
https://doi.org/10.1039/P19810002010
4-Hydroxy-3,7,8-trimethoxy-17-methyl-7,8-didehydrohasubanan-6-one 281986 Click to see 359.40 unknown https://doi.org/10.1021/NP100009J
8-Hydroxy-3,4-dimethoxy-17-methyl-17-azatetracyclo[8.4.3.01,10.02,7]heptadeca-2(7),3,5-triene-11,12-dione 162932486 Click to see 345.40 unknown https://doi.org/10.1248/YAKUSHI1881.1924.514_1034
Aknadilactam 15764659 Click to see 373.40 unknown https://doi.org/10.1021/NP100009J
Aknadinine 159966 Click to see 359.40 unknown https://doi.org/10.1021/NP100009J
Epistephamiersine 91895297 Click to see 389.40 unknown https://doi.org/10.1248/CPB.23.1323
Hasubanonine 442246 Click to see CN1CCC23C1(CCC4=C2C(=C(C=C4)OC)OC)C(=C(C(=O)C3)OC)OC 373.40 unknown https://doi.org/10.1039/P19810002010
Homostephanoline 627343 Click to see 359.40 unknown https://doi.org/10.1021/NP9702042
https://doi.org/10.1248/YAKUSHI1881.48.12_1141
Metaphanine 12312776 Click to see 345.40 unknown https://doi.org/10.1248/CPB.32.4223
Oxoepistephamiersine 620874 Click to see 403.40 unknown https://doi.org/10.1016/S0040-4039(01)87165-3
Oxostephabenine 181354 Click to see 493.50 unknown https://doi.org/10.1021/NP50041A005
Oxostephamiersine 101673501 Click to see CN1C(=O)CC23C14CC(C5=C2C(=C(C=C5)OC)OC)OC4(C(C(=O)C3)OC)OC 403.40 unknown https://doi.org/10.1248/CPB.23.1323
https://doi.org/10.1016/S0040-4039(01)87165-3
https://doi.org/10.1021/NP50035A018
Oxostephasunoline 131632942 Click to see CN1C(=O)CC23C14CC(C5=C2C(=C(C=C5)OC)OC)OC4(C(C(C3)O)OC)O 391.40 unknown https://doi.org/10.1021/NP50033A011
Stephamiersine 618347 Click to see CN1CCC23C14CC(C5=C2C(=C(C=C5)OC)OC)OC4(C(C(=O)C3)OC)OC 389.40 unknown https://doi.org/10.1248/CPB.23.1323
Stephasunoline 618654 Click to see 377.40 unknown https://doi.org/10.1248/CPB.23.1323
> Alkaloids and derivatives / Protoberberine alkaloids and derivatives
(7S,13aS)-2,10-dimethoxy-7-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-7-ium-3,9-diol 15432819 Click to see 342.40 unknown https://doi.org/10.1021/NP50022A026
Cyclanoline 3082134 Click to see C[N+]12CCC3=CC(=C(C=C3C1CC4=C(C2)C(=C(C=C4)OC)O)O)OC 342.40 unknown https://doi.org/10.1021/NP50022A026
> Benzenoids / Phenanthrenes and derivatives
(-)-Prostephanaberrine 129317196 Click to see 343.40 unknown https://doi.org/10.1021/NP50046A005
(1R,8S,10S,11R)-11-hydroxy-3,4,12-trimethoxy-17-methyl-18-oxa-17-azapentacyclo[8.4.3.18,11.01,10.02,7]octadeca-2(7),3,5,12-tetraen-16-one 131855570 Click to see 373.40 unknown https://doi.org/10.1021/NP50022A026
(1R,8S,10S,11R)-3,4,12-trimethoxy-17-methyl-18-oxa-17-azapentacyclo[8.4.3.18,11.01,10.02,7]octadeca-2(7),3,5,12-tetraen-11-ol 101289779 Click to see 359.40 unknown https://doi.org/10.1248/YAKUSHI1947.87.4_381
16-Oxoprometaphanine 91895298 Click to see 373.40 unknown https://doi.org/10.1016/0031-9422(75)85252-6
https://doi.org/10.1021/NP9702042
4,12-Dimethoxy-17-methyl-18-oxa-17-azapentacyclo[8.4.3.18,11.01,10.02,7]octadeca-2(7),3,5,12-tetraene-3,11-diol 73810165 Click to see CN1CCC23C14CC(C5=C2C(=C(C=C5)OC)O)OC4(C(=CC3)OC)O 345.40 unknown https://doi.org/10.1021/NP100009J
6,7-Didehydro-8beta,10beta-epoxy-3,4,7-trimethoxy-17-methylhasubanan-8-ol 124222290 Click to see 359.40 unknown https://doi.org/10.1021/NP9702042
8-Hydroxy-3,4,12-trimethoxy-17-methyl-17-azatetracyclo[8.4.3.01,10.02,7]heptadeca-2(7),3,5,12-tetraene-11,16-dione 137796481 Click to see 373.40 unknown https://doi.org/10.1016/0031-9422(75)85252-6
https://doi.org/10.1021/NP9702042
Prometaphanine 91895299 Click to see 359.40 unknown https://doi.org/10.1021/NP9702042
Prostephabyssine 21593990 Click to see 345.40 unknown https://doi.org/10.1021/NP100009J
Prostephanaberrine 184517 Click to see 343.40 unknown https://doi.org/10.1021/NP50046A005
> Benzenoids / Phenol ethers / Anisoles
Protostephanine 632119 Click to see CN1CCC2=CC(=C(C=C2C3=C(CC1)C(=CC(=C3)OC)OC)OC)OC 357.40 unknown https://doi.org/10.1248/YAKUSHI1881.58.3_268
https://doi.org/10.1248/YAKUSHI1881.1927.541_177
https://doi.org/10.1039/P19810002010
> Benzenoids / Tetralins
(1R,8S,11R,12S)-11-amino-3,4-dimethoxy-13-methyl-9-oxa-13-azapentacyclo[9.4.2.18,12.01,12.02,7]octadeca-2(7),3,5-trien-10-one 162417415 Click to see 344.40 unknown https://doi.org/10.1248/CPB.32.4223
11-Amino-3,4-dimethoxy-13-methyl-9-oxa-13-azapentacyclo[9.4.2.18,12.01,12.02,7]octadeca-2(7),3,5-trien-10-one 162981600 Click to see CN1CCC23C14CC(C5=C2C(=C(C=C5)OC)OC)OC(=O)C4(CC3)N 344.40 unknown https://doi.org/10.1248/CPB.32.4223
> Lignans, neolignans and related compounds
(13S)-5-hydroxy-19,20,24-trimethoxy-14-methyl-7,22-dioxa-14,29-diazaheptacyclo[21.6.3.28,11.12,6.113,17.026,31.021,33]hexatriaconta-1(29),2(36),3,5,8,10,17,19,21(33),23,25,31,34-tridecaen-30-one 135778935 Click to see 606.70 unknown https://doi.org/10.1248/CPB.23.1323
(4aR)-3,4,4a,5,18,19-Hexahydro-9,21,22,26-tetramethoxy-4-methyl-2H-1,24:12,15-dietheno-6,10-metheno-16H-pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline 5317122 Click to see 606.70 unknown https://doi.org/10.1248/CPB.23.1323
https://doi.org/10.1248/YAKUSHI1881.1927.541_177
https://doi.org/10.1248/YAKUSHI1881.58.3_268
13,27-Dimethoxy-7-methyl-15,29,31-trioxa-7,22-diazaoctacyclo[19.9.3.216,19.14,30.110,14.03,8.025,33.028,32]heptatriaconta-1(30),2,4(34),10(37),11,13,16,18,25,27,32,35-dodecaene 3423649 Click to see CN1CCC2=CC3=C4C=C2C1CC5=CC(=C(C=C5)OC)OC6=CC=C(CC7C8=C(O4)C(=C(C=C8CCN7)OC)O3)C=C6 562.70 unknown https://doi.org/10.1021/NP9702042
6,12'-Dimethoxy-2,2'-dimethyl-6',7-epoxyoxyacanthan 33352 Click to see 576.70 unknown https://doi.org/10.1021/NP9702042
Epistephanine 275004 Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC(=C(C=C4)OC)OC5=CC=C(CC6=NCCC7=CC(=C(C(=C76)O3)OC)OC)C=C5)OC 606.70 unknown https://doi.org/10.1248/YAKUSHI1881.58.3_268
https://doi.org/10.1248/YAKUSHI1881.1927.541_177
Fangchinoline 73481 Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)O)OC)OC 608.70 unknown https://doi.org/10.1016/J.PHYMED.2014.04.029
https://doi.org/10.1002/JSSC.201401384
Hypoepistephanine 282017 Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC(=C(C=C4)O)OC5=CC=C(CC6=NCCC7=CC(=C(C(=C76)O3)OC)OC)C=C5)OC 592.70 unknown https://doi.org/10.1248/YAKUSHI1881.48.12_1141
Hypopistephanine 6711179 Click to see 592.70 unknown https://doi.org/10.1248/YAKUSHI1881.48.12_1141
Isofangchinoline 321937 Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)O)OC)OC 608.70 unknown https://doi.org/10.1002/JSSC.201401384
https://doi.org/10.1016/J.PHYMED.2014.04.029
Isotrilobine 12310578 Click to see 576.70 unknown https://doi.org/10.1021/NP9702042
Stebisimine 3083913 Click to see 590.70 unknown https://doi.org/10.1248/CPB.23.1323
Trilobine 169007 Click to see CN1CCC2=CC3=C4C=C2C1CC5=CC(=C(C=C5)OC)OC6=CC=C(CC7C8=C(O4)C(=C(C=C8CCN7)OC)O3)C=C6 562.70 unknown https://doi.org/10.1021/NP9702042

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