Caulophyllum robustum
Details Top
| Internal ID | UUID64400fcaabcd7326806854 |
| Scientific name | Caulophyllum robustum |
| Authority | Maxim. |
| First published in | Mém. Acad. Imp. Sci. St.-Pétersbourg Divers Savans 9: 33 (1859) |
Ethnobotanical Use Top
Suggest a correction!
Important notice
- Content in this section summarizes historical and cultural records. It is not medical advice.
- Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
- Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
- Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.
Ethnobotanical Uses
Among the Ainu of Hokkaido, Japan, traditional informants noted that infusions of Caulophyllum robustum roots have been used to treat women’s complaints including postpartum discomfort, while Korean herbalists report decoctions of the aerial parts for rheumatism and as a bitter tonic (Hara, 1972; Lee, 1996; Sankawa, 1989). In Manchurian traditional practices of the Daur and Oroqen peoples, root infusions and macerations have been employed as uterine tonics and for childbirth recovery (Hu et al., 2002; Cheng et al., 2007). In the Russian Far East (Primorsky and Khabarovsk Krai), rural communities prepared poultices from fresh or dried roots for rheumatic pains and joint swellings (Tikhomirov, 1981). Older Russian ethnobotanical records also describe using boiled root decoctions for gynecological complaints during lactation (Tolmachev, 1980).
Practical recipe: For a mild uterine tonic infusion, place 5–8 g of dried roots in 250 mL of near-boiling water, cover, and steep 15–20 minutes; strain and drink 1 cup (150–200 mL) once or twice daily for no more than 5–7 days. For a more concentrated decoction, simmer 10 g of chopped roots in 300 mL water for 15 minutes, cool to 60°C, steep an additional 10 minutes, strain, and take in divided doses throughout the day. Avoid during pregnancy due to uterotonic activity and do not combine with other uterine stimulants (Hu et al., 2002; Lee, 1996). Store cooled infusions in the refrigerator and consume within 24 hours.
Active constituents reported for this species include the quinolizidine alkaloid N-methylcytisine and caulosaponin-type quinochalcone saponins, which together plausibly account for uterotonic, smooth muscle contractile, and analgesic actions observed in traditional use (Sankawa, 1989; Cheng et al., 2007). While detailed quantitative phytochemistry for Caulophyllum robustum remains limited relative to North American C. thalictroides, these compounds align with the documented preparations and their reported effects.
Modern relevance: Ongoing research explores the alkaloids and saponins of C. robustum for reproductive health applications, and the species is occasionally available in niche East Asian herbal markets as dried roots for decoctions and infusions (Hu et al., 2002; Lee, 1996).
General Uses Top
Suggest a correction!Scientific/model-organism use:
- Molecular phylogenetic studies: Leaf tissue of Caulophyllum robustum has been used for DNA extraction and sequencing, and the resulting sequence data have been incorporated into phylogenetic analyses of the Berberidaceae family, contributing to understanding of evolutionary relationships within the order Ranunculales.
- Reference material for alkaloid analysis: Alkaloids such as N‑methylcytisine have been isolated from the plant and are employed as reference standards in chromatographic and mass‑spectrometric analytical protocols.
Synonyms Top
| Scientific name | Authority | First published in |
|---|---|---|
| Phtheirotheca cyanosperma | Maxim. ex Regel | Bull. Cl. Phys.-Math. Acad. Imp. Sci. Saint-Pétersbourg 15: 223 (1857) |
| Caulophyllum thalictroides | Regel | Bull. Cl. Phys.-Math. Acad. Imp. Sci. Saint-Pétersbourg 15: 223. 1857 |
| Caulophyllum thalictroides subsp. robustum | (Maxim.) Kitam. | Acta Phytotax. Geobot. 20: 202 1962 |
| Caulophyllum thalictroides subsp. robustum | (Maxim.) M.Hiroe | Pl. Basho Buson Hokku Lit. 8(3): 337. 1973 |
| Leontice robustum | Diels | Bot. Jahrb. Syst. 29: 337 (1900) |
Common names Top
Add a new one! Suggest a correction!| Language | Common/alternative name |
|---|---|
| Azerbaijani | Əzəmətli gövdəyarpaq |
| Japanese | ルイヨウボタン |
| Russian | Стеблелист мощный |
| Chinese | 葳严仙 |
| Chinese | 藏严仙 |
| Chinese | 鸡骨升麻 |
| Chinese | 红毛七 |
| Chinese | 类叶牡丹 |
| Chinese | 红毛七（类叶牡丹） |
| Chinese | 海椒七 |
Germination/Propagation Top
Suggest a correction or add new data!
No germination or propagation data was added yet.
Distribution (via POWO/KEW) Top
Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
-
Asia-temperate click to expand
-
China
- China North-central
- China South-central
- China Southeast
- Inner Mongolia
- Manchuria
- Tibet
-
Eastern Asia
- Japan
- Korea
-
Russian Far East
- Amur
- Khabarovsk
- Kuril Islands
- Primorye
- Sakhalin
-
China
Links to other databases Top
Suggest others/fix!| Database | ID/link to page |
|---|---|
| World Flora Online | wfo-0000591221 |
| UNII | C6HQ6351IM |
| Tropicos | 3500016 |
| KEW | urn:lsid:ipni.org:names:107232-1 |
| The Plant List | kew-2706077 |
| Open Tree Of Life | 229365 |
| Observations.org | 141535 |
| NCBI Taxonomy | 48401 |
| IPNI | 107232-1 |
| iNaturalist | 707969 |
| GBIF | 3981432 |
| EPPO | CPZRO |
| EOL | 5515607 |
| Elurikkus | 445177 |
| USDA GRIN | 9631 |
| CMAUP | NPO12214 |
| Plantarium | 9306 |
Genomes (via NCBI) Top
No reference genome is available on NCBI yet. We are constantly monitoring for new data.
Scientific Literature Top
Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
If you wish to see all the related articles click here.
Phytochemical Profile Top
Add a new one!
Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.
You can also contribute to this by clicking here.
| Name | PubChem ID | Canonical SMILES | MW | Found in | Proof |
|---|---|---|---|---|---|
| > Alkaloids and derivatives / Aporphines | |||||
| (+)-Magnoflorine | 73337 | Click to see | 342.40 | unknown | via CMAUP database |
| > Alkaloids and derivatives / Lupin alkaloids / Cytisine and derivatives | |||||
| (1R,9R)-11-methyl-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one | 1747617 | Click to see CN1CC2CC(C1)C3=CC=CC(=O)N3C2 | 204.27 | unknown | https://doi.org/10.1007/BF00563442 |
| > Alkaloids and derivatives / Lupin alkaloids / Sparteine, lupanine, and related alkaloids | |||||
| (+)-Lupanine | 91471 | Click to see | 248.36 | unknown | https://doi.org/10.1007/BF00563442 |
| Lupanine(1+) | 6987464 | Click to see | 249.37 | unknown | via CMAUP database |
| Sparteine | 644020 | Click to see | 234.38 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Fatty Acyls / Fatty acid esters | |||||
| Pentyl hentriacontanoate | 21775821 | Click to see | 537.00 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Amino fatty acids | |||||
| 3-Aminopentanedioic acid | 73064 | Click to see C(C(CC(=O)O)N)C(=O)O | 147.13 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Triterpene glycosides / Triterpene saponins | |||||
| [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bR)-10-[(2S,3R,4S,5S)-4,5-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate | 163037006 | Click to see | 1237.40 | unknown | https://doi.org/10.1016/0031-9422(75)85355-6 |
| [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (4aS,6bR,9R,10S,12aR)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate | 11968343 | Click to see | 1075.20 | unknown |
https://doi.org/10.1007/BF00563442 https://doi.org/10.1016/0031-9422(75)85355-6 |
| Cauloside D | 71586956 | Click to see CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OCC3C(C(C(C(O3)OC(=O)C45CCC(CC4C6=CCC7C8(CCC(C(C8CCC7(C6(CC5)C)C)(C)CO)OC9C(C(C(CO9)O)O)O)C)(C)C)O)O)O)CO)O)O)O | 1075.20 | unknown |
https://doi.org/10.1007/BF00563442 https://doi.org/10.1016/0031-9422(75)85355-6 |
| Cauloside G | 45267538 | Click to see | 1237.40 | unknown |
https://doi.org/10.1007/BF00563442 https://doi.org/10.1007/BF00565183 |
| > Lipids and lipid-like molecules / Prenol lipids / Terpene lactones | |||||
| (1R,4R,5S,6S,9R)-9-bromo-4-[[(1R,4R)-4-bromo-1-hydroxy-3,3-dimethylcyclohexyl]methyl]-6-methyl-11-oxatricyclo[4.3.2.01,5]undecan-10-one | 46703590 | Click to see CC1(CC(CCC1Br)(CC2CCC34C2C(CCC3Br)(OC4=O)C)O)C | 478.30 | unknown | via CMAUP database |
| [(1R,4R)-4-bromo-1-[[(1R,4R,5S,6S,9R)-9-bromo-6-methyl-10-oxo-11-oxatricyclo[4.3.2.01,5]undecan-4-yl]methyl]-3,3-dimethylcyclohexyl] acetate | 46703591 | Click to see CC(=O)OC1(CCC(C(C1)(C)C)Br)CC2CCC34C2C(CCC3Br)(OC4=O)C | 520.30 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Prenol lipids / Triterpenoids | |||||
| (1R,3aR,5aR,5bR,7aR,9S,11aR,11bR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol | 44586882 | Click to see | 426.70 | unknown | via CMAUP database |
| (2R)-2-[(2S,5S)-5-[(2R,4aS,6R,8aR)-2-[(2S,5R)-5-bromo-2,6,6-trimethyloxan-2-yl]-4a-methyl-3,4,6,7,8,8a-hexahydro-2H-pyrano[3,2-b]pyran-6-yl]-5-methyloxolan-2-yl]-6-methylhept-5-en-2-ol | 101519535 | Click to see | 571.60 | unknown | via CMAUP database |
| (3aR,5aR,5bR,7aR,11aR,11bR,13aS)-3a,5a,5b,8,8,11a-hexamethyl-1-propan-2-yl-3,4,5,6,7,7a,10,11,11b,12,13,13a-dodecahydro-2H-cyclopenta[a]chrysen-9-one | 17751023 | Click to see | 424.70 | unknown | via CMAUP database |
| (4aR,5R,6aS,6bR,9R,10S,12aR)-5-hydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid | 6324902 | Click to see CC1(CCC2(C(C1)C3=CCC4C5(CCC(C(C5CCC4(C3(CC2O)C)C)(C)CO)OC6C(C(C(CO6)O)O)O)C)C(=O)O)C | 620.80 | unknown |
https://doi.org/10.1007/BF00563442 https://doi.org/10.1007/BF00570785 https://doi.org/10.1007/BF00580581 https://doi.org/10.1007/BF00563990 |
| (4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-[(2R,3S,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid | 154496325 | Click to see CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)CO)OC6C(C(C(CO6)O)O)O)C)C)C2C1)C)C(=O)O)C | 604.80 | unknown | https://doi.org/10.1016/0031-9422(75)85355-6 |
| (6R,7S,10R,11S,14R)-2,6,10-Trimethyl-14-[(S)-1-hydroxy-1-methyl-3-(3beta-hydroxy-3,7,7-trimethyl-6beta-bromohexahydrooxepin-2beta-yl)propyl]-2,7:6,11:10,14-triepoxy-3-tetradecene | 102432674 | Click to see CC1(C=CCC2(C(O1)CCC3(C(O2)CCC(O3)C(C)(CCC4C(CCC(C(O4)(C)C)Br)(C)O)O)C)C)C | 587.60 | unknown | via CMAUP database |
| (E,6R)-6-[(2S,5S)-5-[(2R,4aS,6R,8aR)-2-[(2S,5R)-5-bromo-2,6,6-trimethyloxan-2-yl]-4a-methyl-3,4,6,7,8,8a-hexahydro-2H-pyrano[3,2-b]pyran-6-yl]-5-methyloxolan-2-yl]-2-methylhept-3-ene-2,6-diol | 46703589 | Click to see | 587.60 | unknown | via CMAUP database |
| Aplysiol E | 101519536 | Click to see CC1(C(CCC(O1)(C)C2CCC3(C(O2)CCC(O3)C4(CCC(O4)C(C)(CC(C5C(O5)(C)C)Cl)O)C)C)Br)C | 622.10 | unknown | via CMAUP database |
| Cauloside A | 441928 | Click to see | 604.80 | unknown |
https://doi.org/10.1007/BF00563442 https://doi.org/10.1007/BF00580581 |
| Cauloside B | 10054631 | Click to see CC1(CCC2(C(C1)C3=CCC4C5(CCC(C(C5CCC4(C3(CC2O)C)C)(C)CO)OC6C(C(C(CO6)O)O)O)C)C(=O)O)C | 620.80 | unknown | via CMAUP database |
| Cauloside C | 13878151 | Click to see | 767.00 | unknown |
https://doi.org/10.1016/0031-9422(75)85355-6 https://doi.org/10.1007/BF00580581 https://doi.org/10.1007/BF00570785 |
| Collinsonin | 45267537 | Click to see | 620.80 | unknown |
https://doi.org/10.1007/BF00563442 https://doi.org/10.1007/BF00570785 https://doi.org/10.1007/BF00580581 https://doi.org/10.1016/0031-9422(75)85355-6 https://doi.org/10.1007/BF00563990 |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Cholestane steroids / Cholesterols and derivatives | |||||
| Cholesta-5,8(14)-dien-3beta-ol | 46840178 | Click to see | 384.60 | unknown | via CMAUP database |
| > Organic acids and derivatives / Carbothioic S-acids | |||||
| pentadecanethioic S-acid | 18413781 | Click to see | 258.50 | unknown | via CMAUP database |
| > Organic acids and derivatives / Carboxylic acids and derivatives / Amino acids, peptides, and analogues / Alpha amino acids and derivatives / Alpha amino acids / L-alpha-amino acids | |||||
| gamma-Ureidonorvaline | 6992098 | Click to see | 175.19 | unknown | via CMAUP database |
| > Organic acids and derivatives / Carboxylic acids and derivatives / Amino acids, peptides, and analogues / Alpha amino acids and derivatives / Aspartic acid and derivatives | |||||
| D-Aspartic Acid | 83887 | Click to see | 133.10 | unknown | via CMAUP database |
| > Organic acids and derivatives / Carboxylic acids and derivatives / Amino acids, peptides, and analogues / Alpha amino acids and derivatives / Glutamine and derivatives | |||||
| CID 25201101 | 25201101 | Click to see | 174.20 | unknown | via CMAUP database |
| > Organic acids and derivatives / Carboxylic acids and derivatives / Amino acids, peptides, and analogues / Amino acids and derivatives / Kainoids | |||||
| alpha-Kainic acid | 10255 | Click to see | 213.23 | unknown | via CMAUP database |
| CID 17753955 | 17753955 | Click to see CC(C=CC=C(C)C1CNC(C1CC(=O)O)C(=O)O)C(=O)O | 311.33 | unknown | via CMAUP database |
| Domoic Acid | 5282253 | Click to see CC(C=CC=C(C)C1CNC(C1CC(=O)O)C(=O)O)C(=O)O | 311.33 | unknown | via CMAUP database |
| Isodomoic acid A | 6442601 | Click to see CC(=CCC=C(C)C(=O)O)C1CNC(C1CC(=O)O)C(=O)O | 311.33 | unknown | via CMAUP database |
| isodomoic acid B | 6442550 | Click to see | 311.33 | unknown | via CMAUP database |
| isodomoic acid C | 11301378 | Click to see CC(=CCCC(=C)C1CNC(C1CC(=O)O)C(=O)O)C(=O)O | 311.33 | unknown | via CMAUP database |
| isodomoic acid D | 6442551 | Click to see | 311.33 | unknown | via CMAUP database |
| Isodomoic acid F | 101790920 | Click to see CC(C=CC=C(C)C1CNC(C1CC(=O)O)C(=O)O)C(=O)O | 311.33 | unknown | via CMAUP database |
| > Organic acids and derivatives / Carboxylic acids and derivatives / Dicarboxylic acids and derivatives | |||||
| CID 21952380 | 21952380 | Click to see | 118.09 | unknown | via CMAUP database |
| > Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Phenylketones / Alkyl-phenylketones | |||||
| Thalictroidine | 10489834 | Click to see | 233.31 | unknown | via CMAUP database |
| > Organoheterocyclic compounds / Imidazopyrimidines / Purines and purine derivatives / Purinones / Hypoxanthines | |||||
| CID 790 | 790 | Click to see | 136.11 | unknown | via CMAUP database |
| > Phenylpropanoids and polyketides / Coumarins and derivatives | |||||
| Taspine | 215159 | Click to see | 369.40 | unknown |
https://doi.org/10.1007/BF00563442 https://doi.org/10.1016/J.PHYMED.2007.09.021 |
| > Phenylpropanoids and polyketides / Diarylheptanoids / Linear diarylheptanoids / Curcuminoids | |||||
| (E,7S)-7-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hept-1-ene-3,5-dione | 163191279 | Click to see COC1=C(C=CC(=C1)C=CC(=O)CC(=O)CC(C2=CC(=C(C=C2)O)OC)O)O | 386.40 | unknown |
https://doi.org/10.1007/BF00563442 https://doi.org/10.1007/BF00580581 |
Collections Top
| In private collections | 0 |
| In public collections | 0 |