Common products:
Steam-distilled essential oil from leaves and young twigs is the principal commercial product from Piper divaricatum (syn. Piper aduncum). The oil is traded under the vernacular matico.

Fragrance and cosmetics:
The oil is used in fragrance compositions as a warm, spicy–herbaceous note and as a fixative for aromatic blends. Chemotype-dependent quality arises from the dominant phenylpropanoid constituents (e.g., dillapiole–rich types; alternative chemotypes with 1,8-cineole–rich profiles have also been reported). Typical physicochemical measures reported for matico-type leaf oils include specific gravity (ca. 0.94–0.98 at 20 °C), refractive index (ca. 1.51–1.53), and optical rotation near zero. International standards for essential oils (ISO 3216) provide specifications that guide quality control. The oil is also employed in flavor applications in select regional cuisines; non-medicinal food uses refer to aromatic seasoning and flavoring only.

Properties relevant to use:
The presence of high proportions of phenylpropanoic constituents (such as dillapiole) in the oil’s composition underlies its aromatic profile and commercial utility in fragrance and flavor. Oil yield and composition vary with plant part and geographic origin, requiring chemotype characterization by gas chromatography for consistent product quality.

Synonyms Top

Scientific name	Authority	First published in
Piper crassum	Vell.	Fl. Flumin. 25. 1829 [1825 publ. 7 Sep-28 Nov 1829] ; see also Fl. Flumin. Icon. 1: t. 59. 1831. [1827 publ. 29 Oct 1831]
Piper densespicatum	Steud.	Nomencl. Bot. , ed. 2, 2: 340 (1841)
Piper glabrilimbum	C.DC.	Verh. Bot. Vereins Prov. Brandenburg 47: 107 (1905)
Piper willdenowii	Kunth ex Miq.	Fl. Bras. 4(1): 56 (1852)
Schilleria colubrina	Kunth	Linnaea 13: 684 (1840)
Artanthe adenophylla	Miq.	Linnaea 20: 170 (1847)
Artanthe colubrina	Miq.	Syst. Piperac. : 512 (1844)
Artanthe colubrina var. crassa	(Vell.) Miq.	Fl. Bras. 4(1): 57 (1852)
Artanthe colubrina var. crassifolia	Miq.	Linnaea 20: 170 (1847)
Artanthe colubrina var. glandulosa	Miq.	Fl. Bras. 4(1): 57 (1852)
Artanthe meyeri	Miq.	Syst. Piperac. (F.A.W. Miquel) 454.
Artanthe obovata	Miq.	Syst. Piperac. : 508 (1844)
Artanthe subaequalis	C.Presl	Abh. Königl. Böhm. Ges. Wiss. , ser. 5, 6: 226 (1851)
Artanthe tejucensis	Miq.	Syst. Piperac. : 496 (1844)
Piper apiculatum	C.DC.	Prodr. 16(1): 273 (1869)
Piper oblongilimbum	C.DC.	Notizbl. Königl. Bot. Gart. Berlin 6: 448 (1917)
Piper tejucense	C.DC.	Prodr. 16(1): 287 (1869)
Piper tumidicondyli	Trel. in J.F.Macbr.	Publ. Field Columb. Mus., Bot. Ser. 13(2): 247 (1936)
Piper impunctatum	Link	Jahrb. Gewächsk. 1(3): 61 (1820)
Piper crassifolium	C.DC.	Prodr. 16(1): 301 (1869)
Piper leiophyllum	C.DC.	Prodr. 16(1): 297 (1869)
Piper subaequale	C.DC.	Prodr. 16(1): 371 (1869)
Piper belemense	C.DC.	Notizbl. Königl. Bot. Gart. Berlin 6: 458 (1917)
Piper romboutsii	Yunck.	Piperac. N. South Amer. : 395 (1950)
Piper colubrinum var. adenophyllum	(Miq.) C.DC.	Prodr. 16(1): 319 (1869)
Piper praemorsum	Vahl	Eclog. Amer. 1: 4 (1797)
Piper citrifolium	Schott ex Miq.	Fl. Bras. 4(1): 56 (1852)
Piper nitidum	Vahl	Enum. Pl. 1: 314 (1804)
Piper glabellum	C.DC.	Prodr. 16(1): 312 (1869)

Common names Top

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Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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No variety added yet.

Subvarieties (abbr. subvar.) Top

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No subvariety added yet.

Forms (abbr. f.) Top

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No forms added yet.

Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:

- Doubtful data

- Extinct

- Introduced

- Native

Northern America click to expand
- Mexico
  - Mexico Gulf
  - Mexico Southeast

Southern America click to expand
- Brazil
  - Brazil North
  - Brazil Northeast
  - Brazil Southeast
  - Brazil West-central
- Northern South America
  - French Guiana
  - Guyana
  - Suriname
  - Venezuela
- Western South America
  - Bolivia
  - Colombia
  - Ecuador
  - Peru

Links to other databases Top

Suggest others/fix!

Database	ID/link to page
World Flora Online	wfo-0000479097
Tropicos	25003479
INPN	734583
KEW	urn:lsid:ipni.org:names:681224-1
The Plant List	kew-2558305
Open Tree Of Life	416673
NCBI Taxonomy	405324
IPNI	681224-1
iNaturalist	292157
GBIF	4186310
CMAUP	NPO25797

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.

Title

Authors

Publication

Released

IDs

Deciphering anti-infectious compounds from Peruvian medicinal Cordoncillos extract library through multiplexed assays and chemical profiling

Vásquez-Ocmín PG, Cojean S, Roumy V, Marti G, Pomel S, Gadea A, Leblanc K, Dennemont I, Ruiz-Vásquez L, Ricopa Cotrina H, Ruiz Mesia W, Bertani S, Ruiz Mesia L, Maciuk A

Front Pharmacol

05-Jun-2023

PMCID:	PMC10278888
doi:	10.3389/fphar.2023.1100542
PMID:	37342590

Occurrence of Alkenylbenzenes in Plants: Flavours and Possibly Toxic Plant Metabolites

Götz ME, Eisenreich A, Frenzel J, Sachse B, Schäfer B

Plants (Basel)

23-May-2023

PMCID:	PMC10255789
doi:	10.3390/plants12112075
PMID:	37299054

Plant-Derived Bioactive Compounds in the Management of Neurodegenerative Disorders: Challenges, Future Directions and Molecular Mechanisms Involved in Neuroprotection

Shoaib S, Ansari MA, Fatease AA, Safhi AY, Hani U, Jahan R, Alomary MN, Ansari MN, Ahmed N, Wahab S, Ahmad W, Yusuf N, Islam N

Pharmaceutics

23-Feb-2023

PMCID:	PMC10057544
doi:	10.3390/pharmaceutics15030749
PMID:	36986610

Chemical and Biological Studies of Achillea setacea Herba Essential Oil—First Report on Some Antimicrobial and Antipathogenic Features

Marinas IC, Oprea E, Gaboreanu DM, Gradisteanu Pircalabioru G, Buleandra M, Nagoda E, Badea IA, Chifiriuc MC

Antibiotics (Basel)

10-Feb-2023

PMCID:	PMC9952371
doi:	10.3390/antibiotics12020371
PMID:	36830282

Flavonoids from Piper Species as Promising Antiprotozoal Agents against Giardia intestinalis: Structure-Activity Relationship and Drug-Likeness Studies

Ticona JC, Bilbao-Ramos P, Amesty Á, Flores N, Dea-Ayuela MA, Bazzocchi IL, Jiménez IA

Pharmaceuticals (Basel)

10-Nov-2022

PMCID:	PMC9695682
doi:	10.3390/ph15111386
PMID:	36355559

Encapsulation of Essential Oils in Nanocarriers for Active Food Packaging

Sharma S, Mulrey L, Byrne M, Jaiswal AK, Jaiswal S

Foods

05-Aug-2022

PMCID:	PMC9368254
doi:	10.3390/foods11152337
PMID:	35954103

Essential Oil of the Plants Growing in the Brazilian Amazon: Chemical Composition, Antioxidants, and Biological Applications

Ferreira OO, Cruz JN, de Moraes ÂA, de Jesus Pereira Franco C, Lima RR, dos Anjos TO, Siqueira GM, do Nascimento LD, Cascaes MM, de Oliveira MS, Andrade EH

Molecules

08-Jul-2022

PMCID:	PMC9318482
doi:	10.3390/molecules27144373
PMID:	35889245

Molecular Modeling Approaches Can Reveal the Molecular Interactions Established between a Biofilm and the Bioactive Compounds of the Essential Oil of Piper divaricatum

Cruz JN, de Oliveira MS, Andrade EH, Rodrigues Lima R

Molecules

29-Jun-2022

PMCID:	PMC9268680
doi:	10.3390/molecules27134199
PMID:	35807444

Determination of Anti-Alzheimer’s Disease Activity of Selected Plant Ingredients

Tuzimski T, Petruczynik A

Molecules

18-May-2022

PMCID:	PMC9147832
doi:	10.3390/molecules27103222
PMID:	35630702

Toxics or Lures? Biological and Behavioral Effects of Plant Essential Oils on Tephritidae Fruit Flies

Zeni V, Benelli G, Campolo O, Giunti G, Palmeri V, Maggi F, Rizzo R, Lo Verde G, Lucchi A, Canale A

Molecules

29-Sep-2021

PMCID:	PMC8511996
doi:	10.3390/molecules26195898
PMID:	34641444

Essential Oils as a Potential Neuroprotective Remedy for Age-Related Neurodegenerative Diseases: A Review

Abd Rashed A, Abd Rahman AZ, Rathi DN

Molecules

19-Feb-2021

PMCID:	PMC7922935
doi:	10.3390/molecules26041107
PMID:	33669787

Piper Species: A Comprehensive Review on Their Phytochemistry, Biological Activities and Applications

Salehi B, Zakaria ZA, Gyawali R, Ibrahim SA, Rajkovic J, Shinwari ZK, Khan T, Sharifi-Rad J, Ozleyen A, Turkdonmez E, Valussi M, Tumer TB, Monzote Fidalgo L, Martorell M, Setzer WN

Molecules

07-Apr-2019

PMCID:	PMC6479398
doi:	10.3390/molecules24071364
PMID:	30959974

Essential Oils from Neotropical Piper Species and Their Biological Activities

da Silva JK, da Trindade R, Alves NS, Figueiredo PL, Maia JG, Setzer WN

Int J Mol Sci

14-Dec-2017

PMCID:	PMC5751174
doi:	10.3390/ijms18122571
PMID:	29240662

Invertebrates, Fungal Biomass, and Leaf Breakdown in Pools and Riffles of Neotropical Streams

Tavares Martins R, Souza da Silveira L, Pereira Lopes M, Gama Alves R

J Insect Sci

28-Feb-2017

PMCID:	PMC5388313
doi:	10.1093/jisesa/iew113
PMID:	28423423

Bats in urban areas of Brazil: roosts, food resources and parasites in disturbed environments

Nunes H, Rocha FL, Cordeiro-Estrela P

Urban Ecosyst

27-Dec-2016

PMCID:	PMC7089172
doi:	10.1007/s11252-016-0632-3
PMID:	32214783

Phytochemical Profile Top

Add a new one!

Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.

Name	PubChem ID	Canonical SMILES	MW	Found in	Proof
> Alkaloids and derivatives / Aporphines
Cepharadione A	94577	Click to see	305.30	unknown	https://doi.org/10.1055/S-2006-959455
> Benzenoids / Phenol ethers / Anisoles
gamma-Asarone	636750	Click to see COC1=CC(=C(C=C1CC=C)OC)OC	208.25	unknown	https://doi.org/10.1055/S-2006-959455
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Triterpene glycosides / Triterpene saponins
dimethyl (2S,3R,4S,4aR,6aR,6bS,8aS,12aS,14aR,14bR)-2-hydroxy-4,6a,6b,11,11,14b-hexamethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4,8a-dicarboxylate	101630395	Click to see CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C(=O)OC)OC6C(C(C(C(O6)CO)O)O)O)O)C)C)C2C1)C)C(=O)OC)C	692.90	unknown	via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(2S,3R,4S,4aS,6aR,6bS,8aS,12aS,14aR,14bR)-2,3-dihydroxy-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4,8a-dicarboxylic acid	462205	Click to see	502.70	unknown	via CMAUP database
(4aS,6aR,6aS,6bR,8aR,9S,10R,11S,12aR,14bR)-10,11-dihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid	93492873	Click to see	488.70	unknown	via CMAUP database
Bayogenin	12305221	Click to see	488.70	unknown	via CMAUP database
Medicagenic acid	65048	Click to see	502.70	unknown	via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
17-(5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol	86821	Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C	414.70	unknown	https://doi.org/10.1055/S-2006-959455
Stigmast-5-en-3-ol	22012	Click to see	414.70	unknown	https://doi.org/10.1055/S-2006-959455
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / O-glycosyl compounds
(2R,3R,4S,5S,6R)-2-[[(1S,2R,3R,7S,8R)-1,7-dihydroxy-3-(hydroxymethyl)-2,3,5,6,7,8-hexahydro-1H-pyrrolizin-2-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol	21576629	Click to see	351.35	unknown	via CMAUP database
[(8aalpha)-Octahydro-1beta,6alpha,7beta-trihydroxyindolizin]-8alpha-yl beta-D-glucopyranoside	10089286	Click to see C1CN2CC(C(C(C2C1O)OC3C(C(C(C(O3)CO)O)O)O)O)O	351.35	unknown	via CMAUP database
> Organoheterocyclic compounds / Benzodioxoles
5-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)penta-2,4-dienamide	276752	Click to see CC(C)CNC(=O)C=CC=CC1=CC2=C(C=C1)OCO2	273.33	unknown	https://doi.org/10.1002/JAT.1311
Piperlonguminine	5320621	Click to see CC(C)CNC(=O)C=CC=CC1=CC2=C(C=C1)OCO2	273.33	unknown	https://doi.org/10.1002/JAT.1311
> Organoheterocyclic compounds / Indolizidines
6-Epicastanospermine	184806	Click to see	189.21	unknown	via CMAUP database
Castanospermine	54445	Click to see	189.21	unknown	via CMAUP database
Rel-(1R,6R,7S,8S,8aS)-octahydroindolizine-1,6,7,8-tetraol	13959480	Click to see C1CN2CC(C(C(C2C1O)O)O)O	189.21	unknown	via CMAUP database
> Organoheterocyclic compounds / Piperidines
3-Epi-fagomine	10290867	Click to see C1CNC(C(C1O)O)CO	147.17	unknown	via CMAUP database
Fagomine	72259	Click to see	147.17	unknown	via CMAUP database
> Organoheterocyclic compounds / Pyrrolidines
(2R,3S)-2-(hydroxymethyl)pyrrolidin-3-ol	11073391	Click to see	117.15	unknown	via CMAUP database
> Organoheterocyclic compounds / Pyrrolizidines
(1R,2S,3S,7R,8R)-3-(hydroxymethyl)-2,3,5,6,7,8-hexahydro-1H-pyrrolizine-1,2,7-triol	21576628	Click to see C1CN2C(C(C(C2C1O)O)O)CO	189.21	unknown	via CMAUP database
(1R,2S,3S,7S,8R)-3-(hydroxymethyl)-2,3,5,6,7,8-hexahydro-1H-pyrrolizine-1,2,7-triol	21576627	Click to see	189.21	unknown	via CMAUP database
(1S,2R,3R,7S,7aR)-3-Hydroxymethyl-1,2,7-trihydroxypyrrolizidine	453575	Click to see C1CN2C(C(C(C2C1O)O)O)CO	189.21	unknown	via CMAUP database
(1S,2R,3R,7S,8S)-3-(hydroxymethyl)-2,3,5,6,7,8-hexahydro-1H-pyrrolizine-1,2,7-triol	14164813	Click to see C1CN2C(C(C(C2C1O)O)O)CO	189.21	unknown	via CMAUP database
3-(Hydroxymethyl)-1,2,7-trihydroxypyrrolizidine	72360	Click to see	189.21	unknown	via CMAUP database
3,7a-Diepialexine	189605	Click to see C1CN2C(C(C(C2C1O)O)O)CO	189.21	unknown	via CMAUP database
Australine	442628	Click to see C1CN2C(C(C(C2C1O)O)O)CO	189.21	unknown	via CMAUP database
> Phenylpropanoids and polyketides / Isoflavonoids / Isoflav-2-enes / Isoflavones
3-(3,4-Dihydroxy-2-methoxyphenyl)-7-hydroxychromen-4-one	101785462	Click to see	300.26	unknown	via CMAUP database
> Phenylpropanoids and polyketides / Isoflavonoids / O-methylated isoflavonoids / 4-O-methylated isoflavonoids / 3-hydroxy,4-methoxyisoflavonoids
Koparin	5318834	Click to see COC1=C(C(=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)O)O)O	300.26	unknown	via CMAUP database
> Phenylpropanoids and polyketides / Isoflavonoids / O-methylated isoflavonoids / 4-O-methylated isoflavonoids / 4-O-methylisoflavones
Afromosin	5281704	Click to see	298.29	unknown	via CMAUP database

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Piper divaricatum

Table of Contents

Details Top

Ethnobotanical Use Top

General Uses Top

Synonyms Top

Common names Top

Subspecies (abbr. subsp./ssp.) Top

Varieties (abbr. var.) Top

Subvarieties (abbr. subvar.) Top

Forms (abbr. f.) Top

Germination/Propagation Top

Distribution (via POWO/KEW) Top

Links to other databases Top

Genomes (via NCBI) Top

Scientific Literature Top

Phytochemical Profile Top

Gallery Top

Contributors Top

Collections Top