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Hypericum geminiflorum

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Table of Contents

Details
Description
Synonyms
Common Names
Subtypes (subspecies, varieties, subvarieties, forms)
Germination/Propagation
Distribution
Links to other databases
Genome
Scientific Literature
Phytochemical Profile
Biological Material
Contributors
Collections

Details Top

Internal ID UUID6440215401794848967117
Scientific name Hypericum geminiflorum
Authority Hemsl.
First published in Ann. Bot. (Oxford) 9: 144 (1895)

Description Top

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Synonyms Top

Scientific name Authority First published in
Takasagoya geminiflora (Hemsl.) Y.Kimura Bot. Mag. (Tokyo) 50: 501 (1936)
Hypericum pustulosum R.Keller Nat. Pflanzenfam. ed. 2 , 21: 176 (1925)

Common names Top

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Language Common/alternative name
Chinese 双花金丝桃
Chinese 雙花金絲桃

Subspecies (abbr. subsp./ssp.) Top

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Name Authority First published in
Hypericum geminiflorum subsp. geminiflorum
Hypericum geminiflorum subsp. simplicistylum (Hayata) N.Robson Bull. Brit. Mus. (Nat. Hist.), Bot. 12: 295 (1985)

Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

Suggest others/fix!
Database ID/link to page
World Flora Online wfo-0000727669
Tropicos 7801690
KEW urn:lsid:ipni.org:names:433453-1
The Plant List kew-2858169
Open Tree Of Life 344874
NCBI Taxonomy 860794
IPNI 433453-1
iNaturalist 705904
GBIF 7330063
EOL 2889773

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Phagocytosis, Degranulation and Extracellular Traps Release by Neutrophils—The Current Knowledge, Pharmacological Modulation and Future Prospects Gierlikowska B, Stachura A, Gierlikowski W, Demkow U Front Pharmacol 04-May-2021
PMCID:PMC8129565
doi:10.3389/fphar.2021.666732
PMID:34017259
Therapeutic significance of β-glucuronidase activity and its inhibitors: A review Awolade P, Cele N, Kerru N, Gummidi L, Oluwakemi E, Singh P Eur J Med Chem 04-Dec-2019
PMCID:PMC7111419
doi:10.1016/j.ejmech.2019.111921
PMID:31835168
Chalcone: A Privileged Structure in Medicinal Chemistry Zhuang C, Zhang W, Sheng C, Zhang W, Xing C, Miao Z Chem Rev 10-May-2017
PMCID:PMC6131713
doi:10.1021/acs.chemrev.7b00020
PMID:28488435
Cytotoxic Activity and Apoptosis Induction of Hypericum scabrum L. Hamzeloo-Moghadam M, Khalaj A, Malekmohammadi M Iran Red Crescent Med J 24-Oct-2015
PMCID:PMC4640096
doi:10.5812/ircmj.19453
PMID:26568855
Phloroglucinols with antioxidant activity and xanthonolignoids from the heartwood of Hypericum geminiflorum. Wu CC, Yen MH, Yang SC, Lin CN J Nat Prod 01-Jun-2008
doi:10.1021/NP8001145
PMID:18512985
Subject Index N/A 01-Jan-2005
PMCID:PMC7148952
doi:10.1016/S1572-5995(05)80049-3
Phenolics from Hypericum geminiflorum Mei-Ing Chung, Mei-Hsun Lai, Ming-Hong Yen, Ru-Rong Wu, Chun-Nan Lin Elsevier BV 23-Apr-2003
doi:10.1016/S0031-9422(96)00644-9
Hypertricone, a Constituent with a Novel Skeleton, Isolated fromHypericum geminiflorum Jing-Ru Weng, Mei-Ing Chung, Ming-Hong Yen, Chun-Nan Lin, Ru-Rong Wu Wiley 25-Aug-2002
doi:10.1002/1522-2675(20010711)84:7<1976::AID-HLCA1976>3.0.CO;2-5
Antiplatelet and anti-inflammatory constituents and new oxygenated xanthones from Hypericum geminiflorum. Chung MI, Weng JR, Wang JP, Teng CM, Lin CN Planta Med 01-Jan-2002
doi:10.1055/S-2002-19871
PMID:11842322
A new chalcone, xanthones, and a xanthonolignoid from Hypericum geminiflorum. Chung MI, Weng JR, Lai MH, Yen MH, Lin CN J Nat Prod 01-Jul-1999
doi:10.1021/NP980533+
PMID:10425136

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.
Name PubChem ID Canonical SMILES MW Found in Proof
> Lignans, neolignans and related compounds
(R)-[4-[4-[(R)-hydroxy-[(2R)-oxiran-2-yl]methyl]-2,6-dimethoxyphenyl]-3,5-dimethoxyphenyl]-[(2R)-oxiran-2-yl]methanol 163019000 Click to see COC1=CC(=CC(=C1C2=C(C=C(C=C2OC)C(C3CO3)O)OC)OC)C(C4CO4)O 418.40 unknown https://doi.org/10.1021/NP8001145
2,6,2',6'-Tetramethoxy-4,4'-bis(2,3-epoxy-1-hydroxypropyl)biphenyl 85350942 Click to see COC1=CC(=CC(=C1C2=C(C=C(C=C2OC)C(C3CO3)O)OC)OC)C(C4CO4)O 418.40 unknown https://doi.org/10.1021/NP8001145
> Lignans, neolignans and related compounds / Lignan glycosides
2-[4-[[5-(3,4-Dimethoxyphenyl)-4-(hydroxymethyl)oxolan-3-yl]methyl]-2-methoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol 163029784 Click to see COC1=C(C=C(C=C1)C2C(C(CO2)CC3=CC(=C(C=C3)OC4C(C(C(C(O4)CO)O)O)O)OC)CO)OC 536.60 unknown https://doi.org/10.1021/NP8001145
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids
[5-(3-hydroxy-3-methylpent-4-enyl)-1,4a-dimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalen-1-yl]methyl acetate 162930267 Click to see CC(=O)OCC1(CCCC2(C1CCC(=C)C2CCC(C)(C=C)O)C)C 348.50 unknown https://doi.org/10.1021/NP8001145
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Bicyclic monoterpenoids
(2R,3aR)-6-hydroxy-7-[[(1S,2R)-2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclopentyl]methyl]-2-(2-hydroxypropan-2-yl)-3a-methyl-5-(2-methylbutanoyl)-2,3-dihydro-1-benzofuran-4-one 102595861 Click to see CCC(C)C(=O)C1=C(C(=C2C(C1=O)(CC(O2)C(C)(C)O)C)CC3C(CCC3(C)O)C(=C)C)O 460.60 unknown https://doi.org/10.1021/NP8001145
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
(2S,4S,5aS,6S,8R,8aS)-6-acetyl-6-benzoyl-8-hydroxy-8a-(2-hydroxypropan-2-yl)-2,8-dimethyl-7-oxo-3,4,5,5a-tetrahydro-2H-cyclopenta[b]oxepine-4-carboxylic acid 101153552 Click to see CC1CC(CC2C(C(=O)C(C2(O1)C(C)(C)O)(C)O)(C(=O)C)C(=O)C3=CC=CC=C3)C(=O)O 446.50 unknown https://doi.org/10.1002/1522-2675(20010711)84:7<1976::AID-HLCA1976>3.0.CO;2-5
6-acetyl-6-benzoyl-8-hydroxy-8a-(2-hydroxypropan-2-yl)-2,8-dimethyl-7-oxo-3,4,5,5a-tetrahydro-2H-cyclopenta[b]oxepine-4-carboxylic acid 162850843 Click to see CC1CC(CC2C(C(=O)C(C2(O1)C(C)(C)O)(C)O)(C(=O)C)C(=O)C3=CC=CC=C3)C(=O)O 446.50 unknown https://doi.org/10.1002/1522-2675(20010711)84:7<1976::AID-HLCA1976>3.0.CO;2-5
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Diterpene glycosides
[(2S,3R,4R,5S,6R)-2-[[(4S,4aR,7S,10aS,11bS)-7-hydroxy-4,8,11b-trimethyl-9-oxo-2,3,4a,5,6,7,10a,11-octahydro-1H-naphtho[2,1-f][1]benzofuran-4-yl]methoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl] 4-hydroxy-3,5-dimethoxybenzoate 162844379 Click to see CC1=C2C(CC3=C(C2O)CCC4C3(CCCC4(C)COC5C(C(C(C(O5)CO)O)O)OC(=O)C6=CC(=C(C(=C6)OC)O)OC)C)OC1=O 674.70 unknown https://doi.org/10.1021/NP8001145
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(2alpha,3beta)-20(29)-Lupene-2,3,28-triol 74976566 Click to see CC(=C)C1CCC2(C1C3CCC4C(C3(CC2)C)(CCC5C4(CC(C(C5(C)C)O)O)C)C)CO 458.70 unknown https://doi.org/10.1021/NP8001145
Betulinic Acid 64971 Click to see CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)C(=O)O 456.70 unknown https://doi.org/10.1016/S0031-9422(96)00644-9
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(7R,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-7-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one 53756318 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2C(CC4=CC(=O)CCC34C)O)C)C(C)C 428.70 unknown https://doi.org/10.1021/NP8001145
17-(5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 86821 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown https://doi.org/10.1016/S0031-9422(96)00644-9
17-(5-Ethyl-6-methylheptan-2-yl)-7-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one 76066211 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2C(CC4=CC(=O)CCC34C)O)C)C(C)C 428.70 unknown https://doi.org/10.1021/NP8001145
24-Ethylcholest-5-en-3beta-ol 22012 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown https://doi.org/10.1021/NP8001145
https://doi.org/10.1016/S0031-9422(96)00644-9
beta-Sitosterol 3-O-beta-D-galactopyranoside 296119 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C 576.80 unknown https://doi.org/10.1016/S0031-9422(96)00644-9
Sitogluside 5742590 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C 576.80 unknown https://doi.org/10.1016/S0031-9422(96)00644-9
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Cyclic ketones / Cyclohexenones
(2'S,3R,3aS,5R,7R,7aS)-3,5',7-trihydroxy-2',3,7-trimethyl-4'-(2-methylbutanoyl)-2'-(3-methylbut-2-enyl)spiro[1,2,3a,4,6,7a-hexahydroindene-5,6'-cyclohex-4-ene]-1',3'-dione 24898465 Click to see CCC(C)C(=O)C1=C(C2(CC3C(CCC3(C)O)C(C2)(C)O)C(=O)C(C1=O)(C)CC=C(C)C)O 460.60 unknown https://doi.org/10.1021/NP8001145
> Organoheterocyclic compounds / Benzodioxanes / Phenylbenzodioxanes / Phenylbenzo-1,4-dioxanes
(2R,3R)-3-(3-hydroxy-4-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-2,3-dihydro-[1,4]dioxino[2,3-c]xanthen-7-one 162976502 Click to see COC1=C(C=C(C=C1)C2C(OC3=C4C(=CC(=C3O2)OC)C(=O)C5=CC=CC=C5O4)CO)O 436.40 unknown https://doi.org/10.1021/NP8001145
(2R,3R)-8-hydroxy-3-(4-hydroxy-3,5-dimethoxyphenyl)-2-(hydroxymethyl)-10-methoxy-2,3-dihydro-[1,4]dioxino[2,3-c]xanthen-7-one 162915864 Click to see COC1=CC(=C2C(=C1)OC3=C(C2=O)C=CC4=C3OC(C(O4)C5=CC(=C(C(=C5)OC)O)OC)CO)O 482.40 unknown https://doi.org/10.1021/NP8001145
(2S,3S)-8-hydroxy-3-(4-hydroxy-3,5-dimethoxyphenyl)-2-(hydroxymethyl)-10-methoxy-2,3-dihydro-[1,4]dioxino[2,3-c]xanthen-7-one 162915862 Click to see COC1=CC(=C2C(=C1)OC3=C(C2=O)C=CC4=C3OC(C(O4)C5=CC(=C(C(=C5)OC)O)OC)CO)O 482.40 unknown https://doi.org/10.1021/NP8001145
3-(3-Hydroxy-4-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-2,3-dihydro-[1,4]dioxino[2,3-c]xanthen-7-one 162976501 Click to see COC1=C(C=C(C=C1)C2C(OC3=C4C(=CC(=C3O2)OC)C(=O)C5=CC=CC=C5O4)CO)O 436.40 unknown https://doi.org/10.1021/NP8001145
3-(4-Hydroxy-3,5-dimethoxyphenyl)-2-(hydroxymethyl)-5-methoxy-2,3-dihydro-[1,4]dioxino[2,3-c]xanthen-7-one 13834089 Click to see COC1=CC(=CC(=C1O)OC)C2C(OC3=C4C(=CC(=C3O2)OC)C(=O)C5=CC=CC=C5O4)CO 466.40 unknown https://doi.org/10.1021/NP8001145
Cadensin D 190366 Click to see COC1=CC(=CC(=C1O)OC)C2C(OC3=C4C(=CC(=C3O2)OC)C(=O)C5=CC=CC=C5O4)CO 466.40 unknown https://doi.org/10.1021/NP8001145
Gemixanthone A 10601833 Click to see COC1=CC(=CC(=C1O)OC)C2C(OC3=C(C=C4C(=C3O2)OC5=C(C4=O)C(=CC(=C5)O)OC)OC)CO 512.50 unknown https://doi.org/10.1021/NP980533+
Hyperielliptone HC 102595862 Click to see COC1=CC(=C2C(=C1)OC3=C(C2=O)C=CC4=C3OC(C(O4)C5=CC(=C(C(=C5)OC)O)OC)CO)O 482.40 unknown https://doi.org/10.1021/NP8001145
Kielcorin 13834128 Click to see COC1=C(C=CC(=C1)C2C(OC3=C4C(=CC(=C3O2)OC)C(=O)C5=CC=CC=C5O4)CO)O 436.40 unknown https://doi.org/10.1021/NP8001145
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones
1-Hydroxyxanthone 5376036 Click to see C1=CC=C2C(=C1)C(=O)C3=C(C=CC=C3O2)O 212.20 unknown https://doi.org/10.1021/NP8001145
1,3,8-Trihydroxy-2-methoxyxanthone 14756212 Click to see COC1=C(C2=C(C=C1O)OC3=CC=CC(=C3C2=O)O)O 274.22 unknown https://doi.org/10.1021/NP8001145
1,3,8-Trihydroxy-4-methoxy-9H-xanthen-9-one 71330160 Click to see COC1=C(C=C(C2=C1OC3=CC=CC(=C3C2=O)O)O)O 274.22 unknown https://doi.org/10.1021/NP8001145
1,5-Dihydroxy-6-methoxy-9H-xanthen-9-one 15957491 Click to see COC1=C(C2=C(C=C1)C(=O)C3=C(C=CC=C3O2)O)O 258.23 unknown https://doi.org/10.1021/NP8001145
2,3-Dihydroxy-1,6,7-trimethoxyxanthone 91508983 Click to see COC1=C(C=C2C(=C1)C(=O)C3=C(O2)C=C(C(=C3OC)O)O)OC 318.28 unknown https://doi.org/10.1055/S-2002-19871
2,3-Dimethoxyxanthen-9-one 253955 Click to see COC1=C(C=C2C(=C1)C(=O)C3=CC=CC=C3O2)OC 256.25 unknown https://doi.org/10.1021/NP8001145
2H,10H-[1,3]Dioxolo[4,5-B]xanthen-10-one 14189052 Click to see C1OC2=C(O1)C=C3C(=C2)C(=O)C4=CC=CC=C4O3 240.21 unknown https://doi.org/10.1021/NP8001145
3,6-Dihydroxy-1,5,7-trimethoxyxanthone 91205255 Click to see COC1=CC(=CC2=C1C(=O)C3=CC(=C(C(=C3O2)OC)O)OC)O 318.28 unknown https://doi.org/10.1055/S-2002-19871
4-Hydroxy-1,2-dimethoxyxanthone 54450736 Click to see COC1=C(C2=C(C(=C1)O)OC3=CC=CC=C3C2=O)OC 272.25 unknown https://doi.org/10.1021/NP980533+
6,7-Dihydroxy-1,3-dimethoxyxanthone 54166548 Click to see COC1=CC2=C(C(=C1)OC)C(=O)C3=CC(=C(C=C3O2)O)O 288.25 unknown https://doi.org/10.1021/NP980533+
9H-Xanthen-9-one, 1,8-dihydroxy-3-methoxy- 5479780 Click to see COC1=CC(=C2C(=C1)OC3=CC=CC(=C3C2=O)O)O 258.23 unknown https://doi.org/10.1021/NP8001145
Euxanthone 5281631 Click to see C1=CC(=C2C(=C1)OC3=C(C2=O)C=C(C=C3)O)O 228.20 unknown https://doi.org/10.1021/NP8001145
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones / Pyranoxanthones
toxyloxanthone B 14886044 Click to see CC1(C=CC2=C(O1)C(=CC3=C2C(=O)C4=C(C=C(C=C4O3)O)O)O)C 326.30 unknown https://doi.org/10.1021/NP980533+
> Organoheterocyclic compounds / Isoquinolines and derivatives / Isoquinoline quinones
7-Desmethyl-6-methylbostrycoidin 132967559 Click to see CC1=CC2=C(C=N1)C(=O)C3=C(C2=O)C(=C(C=C3O)O)OC 285.25 unknown https://doi.org/10.1021/NP8001145
> Phenylpropanoids and polyketides / Flavonoids / Pyranoflavonoids
3,8-dihydroxy-10-methoxy-9-[(E)-3-methylbut-1-enyl]-6-(2-methylprop-1-enyl)-6H-chromeno[4,3-b]chromen-7-one 5458462 Click to see CC(C)C=CC1=C(C=C2C(=C1O)C(=O)C3=C(O2)C4=C(C=C(C=C4)O)OC3C=C(C)C)OC 434.50 unknown https://doi.org/10.1055/S-2002-19871
https://doi.org/10.1016/S0031-9422(96)00644-9
cudraflavone A 5316261 Click to see CC(=CC1C2=C(C3=C(O1)C=C(C=C3)O)OC4=CC5=C(C=CC(O5)(C)C)C(=C4C2=O)O)C 418.40 unknown https://doi.org/10.1016/S0031-9422(96)00644-9
> Phenylpropanoids and polyketides / Linear 1,3-diarylpropanoids / Chalcones and dihydrochalcones / 3-prenylated chalcones
Gemichalcone A 10006762 Click to see CC(=CCC1=C(C=CC(=C1O)C(=O)C=CC2=CC=C(C=C2)O)O)COC(=O)C=CC3=CC(=C(C=C3)O)OC 516.50 unknown https://doi.org/10.1055/S-2002-19871
https://doi.org/10.1016/S0031-9422(96)00644-9
Gemichalcone B 10413126 Click to see CC(=CCC1=C(C=CC(=C1O)C(=O)C=CC2=CC=C(C=C2)O)O)COC(=O)C=CC3=CC=C(C=C3)O 486.50 unknown https://doi.org/10.1055/S-2002-19871
https://doi.org/10.1016/S0031-9422(96)00644-9
Gemichalcone C 10626094 Click to see CC(=CCC1=C(C=CC(=C1O)C(=O)C=CC2=C(C=C(C=C2)O)O)O)COC(=O)C=CC3=CC(=C(C=C3)O)OC 532.50 unknown https://doi.org/10.1021/NP980533+
Isobavachalcone 5281255 Click to see CC(=CCC1=C(C=CC(=C1O)C(=O)C=CC2=CC=C(C=C2)O)O)C 324.40 unknown https://doi.org/10.1016/S0031-9422(96)00644-9
isogemichalcone B 42607532 Click to see CC(=CCC1=C(C=CC(=C1O)C(=O)C=CC2=CC=C(C=C2)O)O)COC(=O)C=CC3=CC=C(C=C3)O 486.50 unknown https://doi.org/10.1016/S0031-9422(96)00644-9
> Phenylpropanoids and polyketides / Macrolactams
(7Z,9S,10S,11S,12Z,14S,16Z,20S,21S,22Z,24Z,26Z)-31-chloro-4,10,14,20-tetrahydroxy-3,7,9,11,17,21,27-heptamethyl-29-azatricyclo[28.3.1.05,33]tetratriaconta-1(33),2,4,7,12,16,22,24,26,30-decaene-6,18,28,32,34-pentone 101636761 Click to see CC1C=CC=CC=C(C(=O)NC2=C(C(=O)C3=C(C2=O)C=C(C(=C3C(=O)C(=CC(C(C(C=CC(CC=C(C(=O)CC1O)C)O)C)O)C)C)O)C)Cl)C 720.20 unknown https://doi.org/10.1021/NP8001145
> Phenylpropanoids and polyketides / Macrolides and analogues / Zearalenones
(2S,3R,5R,7S,9Z,12S)-2,3,16-trihydroxy-18-methoxy-12-methyl-6,13-dioxatricyclo[13.4.0.05,7]nonadeca-1(15),9,16,18-tetraene-8,14-dione 163185336 Click to see CC1CC=CC(=O)C2C(O2)CC(C(C3=C(C(=CC(=C3)OC)O)C(=O)O1)O)O 378.40 unknown https://doi.org/10.1021/NP8001145

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