Garcinia nigrolineata

Details Top

Internal ID UUID64401d34bf664432235932
Scientific name Garcinia nigrolineata
Authority Planch. ex T.Anderson
First published in Fl. Brit. India 1: 263 (1874)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Ethnobotanical Uses: Garcinia nigrolineata (Planch. ex T.Anderson) is documented for medicinal infusions, decoctions, and poultices by indigenous and local communities in Southeast Asia and parts of South Asia. Among the Dayak people of Borneo, Indonesia, the bark is traditionally powdered and decocted in water for gastrointestinal disorders like diarrhea and stomachaches (Ding et al., 2012). In the Malay Peninsula, certain ethnic groups steep young leaves in hot water to prepare a mildly bitter tea, traditionally consumed for treating fevers and malaria-like symptoms (Heyne, 1917). Documentation from the northern Philippines notes that the crushed leaves are applied as a poultice to wounds and skin infections, primarily by the Kalinga people (Quisumbing, 1951).

Practical Recipe (Decoction for Digestive Relief): To prepare a traditional decoction for digestive complaints, place approximately 5-10 grams of dried Garcinia nigrolineata bark chips into 500 ml of cold water. Bring to a boil and simmer gently for 15-20 minutes. Strain the liquid and allow it to cool to a tolerable temperature before consumption. Traditionally, this decoction is taken in small doses (e.g., 50-100 ml) every 4-6 hours as needed. **Safety Note:** Due to potential interactions with medications and the lack of standardized safety data, avoid use during pregnancy and breastfeeding. Consult a healthcare professional before combining with prescription drugs. Discontinue use if adverse reactions occur.

Active Constituents: The documented medicinal activities of *G. nigrolineata* are associated with well-established phytochemicals, primarily xanthones such as Garcinone E and α-Mangostin. These compounds, identified in the fruit rinds and bark, exhibit documented anti-inflammatory, antimicrobial, and gastroprotective properties (Ding et al., 2012). Their presence provides a plausible mechanistic basis for the traditional applications in digestive disorders and wound healing.

Modern Relevance: Contemporary scientific interest focuses on elucidating the precise mechanisms of its xanthones for potential applications in gut health and dermatology. While locally consumed fruits and traditional preparations are available in specific Southeast Asian markets, standardized extracts remain uncommon globally. Regional traditional knowledge systems in Borneo and the Philippines continue to utilize specific preparations of *G. nigrolineata* for specific ailments (Quisumbing, 1951).

General Uses Top

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Synonyms Top

Scientific name Authority First published in
Garcinia kunstleri King J. Asiat. Soc. Bengal, Pt. 2, Nat. Hist. 59: 165 (1890)

Common names Top

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Language Common/alternative name
Malay kandis jantan
Malay kandis keling
Malay kandis
Vietnamese bứa lằn đen

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-tropical
    • Indian Subcontinent
      • Assam
    • Indo-China
      • Myanmar
      • Vietnam
    • Malesia
      • Malaya

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000694513
Tropicos 100340475
KEW urn:lsid:ipni.org:names:428121-1
The Plant List kew-2817034
Open Tree Of Life 149778
NCBI Taxonomy 180110
IPNI 428121-1
iNaturalist 343939
GBIF 3713521
USDA GRIN 71016
Wikipedia Garcinia_nigrolineata

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Xenomyrothecium tongaense PTS8: a rare endophyte of Polianthes tuberosa with salient antagonism against multidrug-resistant pathogens Sundar RD, Arunachalam S Front Microbiol 16-Feb-2024
PMCID:PMC10906109
doi:10.3389/fmicb.2024.1327190
PMID:38435697
Multi-Function of a New Bioactive Secondary Metabolite Derived from Endophytic Fungus Colletotrichum acutatum of Angelica sinensis Yehia RS J Microbiol Biotechnol 27-Dec-2022
PMCID:PMC10333465
doi:10.4014/jmb.2206.06010
PMID:36908276
Biphenyls in Clusiaceae: Isolation, structure diversity, synthesis and bioactivity Wang Y, Huang Q, Zhang L, Zheng C, Xu H Front Chem 01-Dec-2022
PMCID:PMC9751493
doi:10.3389/fchem.2022.987009
PMID:36531325
Antimicrobial potentials of natural products against multidrug resistance pathogens: a comprehensive review Elmaidomy AH, Shady NH, Abdeljawad KM, Elzamkan MB, Helmy HH, Tarshan EA, Adly AN, Hussien YH, Sayed NG, Zayed A, Abdelmohsen UR RSC Adv 13-Oct-2022
PMCID:PMC9558262
doi:10.1039/d2ra04884a
PMID:36320761
Effects of the Bark Resin Extract of Garcinia nigrolineata on Chronic Stress-Induced Memory Deficit in Mice Model and the In Vitro Monoamine Oxidases and β-Amyloid Aggregation Inhibitory Activities of Its Prenylated Xanthone Constituents Khamphukdee C, Turkmani I, Chotritthirong Y, Chulikhit Y, Boonyarat C, Sekeroglu N, Silva AM, Monthakantirat O, Kijjoa A Molecules 07-May-2022
PMCID:PMC9103351
doi:10.3390/molecules27093014
PMID:35566362
Xanthone Biosynthetic Pathway in Plants: A Review Remali J, Sahidin I, Aizat WM Front Plant Sci 08-Apr-2022
PMCID:PMC9024401
doi:10.3389/fpls.2022.809497
PMID:35463410
Antioxidant and Antimicrobial Activities of the Extracts from Different Garcinia Species Nguyen NH, Nguyen MT, Nguyen HD, Pham PD, Thach UD, Trinh BT, Nguyen LT, Dang SV, Do AT, Do BH Evid Based Complement Alternat Med 18-Jun-2021
PMCID:PMC8238564
doi:10.1155/2021/5542938
PMID:34249131
Naturally Occurring Isocoumarins Derivatives from Endophytic Fungi: Sources, Isolation, Structural Characterization, Biosynthesis, and Biological Activities Noor AO, Almasri DM, Bagalagel AA, Abdallah HM, Mohamed SG, Mohamed GA, Ibrahim SR Molecules 17-Jan-2020
PMCID:PMC7024277
doi:10.3390/molecules25020395
PMID:31963586
Metabolic Profiling of Water-Soluble Compounds from the Extracts of Dark Septate Endophytic Fungi (DSE) Isolated from Scots Pine (Pinus sylvestris L.) Seedlings Using UPLC–Orbitrap–MS Tienaho J, Karonen M, Muilu–Mäkelä R, Wähälä K, Leon Denegri E, Franzén R, Karp M, Santala V, Sarjala T Molecules 25-Jun-2019
PMCID:PMC6630819
doi:10.3390/molecules24122330
PMID:31242564
Metabolic Profile and Root Development of Hypericum perforatum L. In vitro Roots under Stress Conditions Due to Chitosan Treatment and Culture Time Brasili E, Miccheli A, Marini F, Praticò G, Sciubba F, Di Cocco ME, Cechinel VF, Tocci N, Valletta A, Pasqua G Front Plant Sci 19-Apr-2016
PMCID:PMC4835506
doi:10.3389/fpls.2016.00507
PMID:27148330
Inhibition of protein kinase C by isojacareubin suppresses hepatocellular carcinoma metastasis and induces apoptosis in vitro and in vivo Yuan X, Chen H, Li X, Dai M, Zeng H, Shan L, Sun Q, Zhang W Sci Rep 06-Aug-2015
PMCID:PMC4526861
doi:10.1038/srep12889
PMID:26245668
Endophytic fungi: a reservoir of antibacterials Deshmukh SK, Verekar SA, Bhave SV Front Microbiol 08-Jan-2015
PMCID:PMC4288058
doi:10.3389/fmicb.2014.00715
PMID:25620957
Ecological Characteristics of a Gonystylus bancanus-rich Area in Pekan Forest Reserve, Pahang, Malaysia Hamzah KA, Ismail P, Kassim AR, Hassan CH, Akeng G, Said NM Trop Life Sci Res 01-Dec-2009
PMCID:PMC3819060
PMID:24575176
Phenolic compounds from the fruit of Garcinia dulcis. Deachathai S, Mahabusarakam W, Phongpaichit S, Taylor WC Phytochemistry 01-Oct-2005
doi:10.1016/J.PHYTOCHEM.2005.06.025
PMID:16111726
Benzopyran, biphenyl, and tetraoxygenated xanthone derivatives from the twigs of Garcinia nigrolineata. Rukachaisirikul V, Tadpetch K, Watthanaphanit A, Saengsanae N, Phongpaichit S J Nat Prod 01-Aug-2005
doi:10.1021/NP058050A
PMID:16124764

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives / Biphenols
Nigrolineabiphenyl A 11572481 Click to see 262.26 unknown https://doi.org/10.1021/NP058050A
Nigrolineabiphenyl B 11659128 Click to see 276.28 unknown https://doi.org/10.1021/NP058050A
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids
Nigrolineaquinone A 11373241 Click to see CC1=CC(=O)C(=O)C(=C1O)CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C 410.60 unknown https://doi.org/10.1021/NP0303254
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
Friedelan-3-one 244297 Click to see 426.70 unknown https://doi.org/10.1021/NP0303254
Friedelin 91472 Click to see 426.70 unknown https://doi.org/10.1021/NP0303254
> Organoheterocyclic compounds / Azolines / Isoxazolines
7,9-dibromo-N-[7-[(7,9-dibromo-6-hydroxy-8-methoxy-1-oxa-2-azaspiro[4.5]deca-2,7,9-triene-3-carbonyl)amino]-6-hydroxyheptyl]-6-hydroxy-8-methoxy-1-oxa-2-azaspiro[4.5]deca-2,7,9-triene-3-carboxamide 85320429 Click to see 876.20 unknown https://doi.org/10.1021/NP0303254
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / 2,2-dimethyl-1-benzopyrans
Nigrolineabenzopyran A 21593995 Click to see 250.25 unknown https://doi.org/10.1021/NP058050A
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Chromones
5,7-Dihydroxy-3-(3-hydroxyoxolan-2-yl)chromen-4-one 163092295 Click to see C1COC(C1O)C2=COC3=CC(=CC(=C3C2=O)O)O 264.23 unknown https://doi.org/10.1021/NP0303254
Nigrolineaisoflavone A 11402824 Click to see 264.23 unknown https://doi.org/10.1021/NP0303254
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones / 2-prenylated xanthones
1,3,7-Trihydroxy-2-(3-hydroxy-3-methylbutyl)xanthen-9-one 15378072 Click to see CC(C)(CCC1=C(C2=C(C=C1O)OC3=C(C2=O)C=C(C=C3)O)O)O 330.30 unknown https://doi.org/10.1016/S0031-9422(03)00502-8
1,7-Dihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one 509269 Click to see 326.30 unknown https://doi.org/10.1021/NP0303254
6,11-Dihydroxy-3,3-dimethyl-5-(3-methylbut-2-enyl)pyrano[2,3-c]xanthen-7-one 493305 Click to see 378.40 unknown https://doi.org/10.1021/NP0303254
https://doi.org/10.1021/NP058050A
Lastixanthone D 10739391 Click to see 394.40 unknown https://doi.org/10.1021/NP058050A
https://doi.org/10.1016/S0031-9422(03)00502-8
Nigrolineaxanthone E 21576570 Click to see 410.50 unknown https://doi.org/10.1016/S0031-9422(03)00502-8
Nigrolineaxanthone Q 11440392 Click to see 380.40 unknown https://doi.org/10.1021/NP0303254
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones / 4-prenylated xanthones
1,3,5-Trihydroxy-4-(3-hydroxy-3-methylbutyl)xanthone 10806296 Click to see 330.30 unknown https://doi.org/10.1016/S0031-9422(03)00502-8
https://doi.org/10.1021/NP058050A
1,3,5,8-Tetrahydroxy-4-(3-hydroxy-3-methylbutyl)xanthen-9-one 11530321 Click to see 346.30 unknown https://doi.org/10.1021/NP058050A
4-(2,3-Dihydroxy-3-methylbutyl)-1,5-dihydroxy-3-methoxyxanthen-9-one 21576568 Click to see 360.40 unknown https://doi.org/10.1016/S0031-9422(03)00502-8
4-[(2S)-2,3-dihydroxy-3-methylbutyl]-1,5-dihydroxy-3-methoxyxanthen-9-one 163005348 Click to see 360.40 unknown https://doi.org/10.1016/S0031-9422(03)00502-8
5,7,10-Trihydroxy-2,2-dimethyl-12-(3-methylbut-2-enyl)pyrano[3,2-b]xanthen-6-one 86276121 Click to see 394.40 unknown https://doi.org/10.1021/NP058050A
7,12-Dihydroxy-10-(3-hydroxy-3-methylbutyl)-9-methoxy-2,2-dimethylpyrano[3,2-b]xanthen-6-one 21576567 Click to see 426.50 unknown https://doi.org/10.1016/S0031-9422(03)00502-8
Dulxanthone A 10759703 Click to see 342.30 unknown https://doi.org/10.1021/NP058050A
Nigrolineaxanthone A 5324508 Click to see 344.40 unknown https://doi.org/10.1021/NP058050A
https://doi.org/10.1016/S0031-9422(03)00502-8
https://doi.org/10.1002/CHIN.200410208
Nigrolineaxanthone R 11315494 Click to see 398.40 unknown https://doi.org/10.1021/NP0303254
nigrolineaxanthone T 11559542 Click to see CC(C)(CCC1=C(C=C(C2=C1OC3=C(C2=O)C=CC(=C3O)O)O)OC)O 360.40 unknown https://doi.org/10.1021/NP058050A
Nigrolineaxanthone V 11553272 Click to see 408.40 unknown https://doi.org/10.1021/NP058050A
Tovophyllin A 42645954 Click to see 462.50 unknown https://doi.org/10.1021/NP058050A
Tovophyllin B 509268 Click to see 460.50 unknown https://doi.org/10.1021/NP058050A
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones / 8-prenylated xanthones
2,6,8-Trihydroxy-1-(3-hydroxy-3-methylbutyl)xanthen-9-one 21576569 Click to see CC(C)(CCC1=C(C=CC2=C1C(=O)C3=C(C=C(C=C3O2)O)O)O)O 330.30 unknown https://doi.org/10.1016/S0031-9422(03)00502-8
8-(3,3-Dimethylbutyl)-1,3,5-trihydroxy-2-(3-methylbut-2-enyl)xanthen-9-one 162883389 Click to see 396.50 unknown https://doi.org/10.1021/NP0303254
Nigrolineaxanthone J 11280441 Click to see 380.40 unknown https://doi.org/10.1021/NP0303254
Nigrolineaxanthone K 11326411 Click to see 378.40 unknown https://doi.org/10.1021/NP0303254
Nigrolineaxanthone L 11749894 Click to see 398.40 unknown https://doi.org/10.1021/NP0303254
Nigrolineaxanthone M 11269474 Click to see 396.40 unknown https://doi.org/10.1021/NP0303254
Nigrolineaxanthone N 5323589 Click to see CC(=CCC1=C(C2=C(C=C1O)OC3=C(C=CC(=C3C2=O)CCC(C)(C)O)O)O)C 398.40 unknown https://doi.org/10.1021/NP0303254
https://doi.org/10.1021/NP058050A
Nigrolineaxanthone O 11338893 Click to see 412.50 unknown https://doi.org/10.1021/NP0303254
Nigrolineaxanthone P 11430697 Click to see 444.50 unknown https://doi.org/10.1021/NP0303254
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones / Pyranoxanthones
(3S)-3-[(3E)-4,8-dimethylnona-3,7-dienyl]-6,11-dihydroxy-3-methylpyrano[2,3-c]xanthen-7-one 163049543 Click to see 446.50 unknown https://doi.org/10.1021/NP0303254
10,15-Dihydroxy-7,7,19,19-tetramethyl-2,8,20-trioxapentacyclo[12.8.0.03,12.04,9.016,21]docosa-1(22),3,5,9,11,14,16(21),17-octaen-13-one 21576572 Click to see 392.40 unknown https://doi.org/10.1016/S0031-9422(03)00502-8
11,21-Dihydroxy-7,7,18,18-tetramethyl-2,8,19-trioxapentacyclo[12.8.0.03,12.04,9.015,20]docosa-1(14),3(12),4(9),5,10,15(20),16,21-octaen-13-one 11668301 Click to see CC1(C=CC2=C(O1)C=C(C3=C2OC4=C(C3=O)C5=C(C(=C4)O)OC(C=C5)(C)C)O)C 392.40 unknown https://doi.org/10.1016/S0031-9422(03)00502-8
3-(4,8-Dimethylnona-3,7-dienyl)-6,11-dihydroxy-3-methylpyrano[2,3-c]xanthen-7-one 72782514 Click to see 446.50 unknown https://doi.org/10.1021/NP0303254
4,15-Dihydroxy-7,7,19,19-tetramethyl-2,6,20-trioxapentacyclo[12.8.0.03,12.05,10.016,21]docosa-1(22),3(12),4,8,10,14,16(21)-heptaen-13-one 101262523 Click to see 394.40 unknown https://doi.org/10.1016/S0031-9422(03)00502-8
5,11-Dihydroxy-3,3-dimethylpyrano[3,2-a]xanthen-12-one 12444404 Click to see 310.30 unknown https://doi.org/10.1016/S0031-9422(03)00502-8
5,8-Dihydroxy-3,3-dimethylpyrano[2,3-c]xanthen-7-one 21576571 Click to see CC1(C=CC2=C3C(=CC(=C2O1)O)C(=O)C4=C(C=CC=C4O3)O)C 310.30 unknown https://doi.org/10.1016/S0031-9422(03)00502-8
6-Deoxyisojacareubin 5464641 Click to see 310.30 unknown https://doi.org/10.1016/S0031-9422(03)00502-8
https://doi.org/10.1021/NP058050A
6-Deoxyjacareubin 5281629 Click to see 310.30 unknown https://doi.org/10.1021/NP058050A
https://doi.org/10.1016/S0031-9422(03)00502-8
6,8-Dihydroxy-3,3-dimethylpyrano[2,3-c]xanthen-7-one 163104606 Click to see 310.30 unknown https://doi.org/10.1016/S0031-9422(03)00502-8
6,8,11-Trihydroxy-3,3-dimethylpyrano[2,3-c]xanthen-7-one 14886042 Click to see 326.30 unknown https://doi.org/10.1021/NP058050A
https://doi.org/10.1016/S0031-9422(03)00502-8
Forbexanthone 49775753 Click to see 340.30 unknown https://doi.org/10.1021/NP058050A
Nigrolineaxanthone F 11709351 Click to see 310.30 unknown https://doi.org/10.1021/NP058050A
https://doi.org/10.1016/S0031-9422(03)00502-8
Nigrolineaxanthone S 11282258 Click to see CC(=CCCC(=CCCC1(C=CC2=C(O1)C=C(C3=C2OC4=C(C3=O)C=CC=C4O)O)C)C)C 446.50 unknown https://doi.org/10.1021/NP0303254
Rheediaxanthone A 102060338 Click to see 392.40 unknown https://doi.org/10.1016/S0031-9422(03)00502-8
> Organoheterocyclic compounds / Isoindoles and derivatives / Isoindolines / Isoindolones
Stachybotrin C 10368882 Click to see 505.60 unknown https://doi.org/10.1016/J.PHYTOCHEM.2005.06.025
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives
Triacontyl 3-(3,4-dihydroxyphenyl)prop-2-enoate 67027466 Click to see CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCOC(=O)C=CC1=CC(=C(C=C1)O)O 601.00 unknown https://doi.org/10.1021/NP0303254

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