Horsfieldia superba - Unknown
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Internal ID UUID644020ded02c7909841561
Scientific name Horsfieldia superba
Authority Warb.
First published in Nova Acta Acad. Caes. Leop.-Carol. German. Nat. Cur. 68: 295 (1897)

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Horsfieldia superba is a species of plant in the family Myristicaceae found in Sumatra, Peninsular Malaysia, and Singapore. It is threatened by habitat loss and is used in traditional herbal medicine. The plant contains an alkaloid called horsfiline, which has analgesic effects, as well as 5-MeO-DMT and 6-methoxy-2-methyl-1,2,3,4-tetrahydro-β-carboline.

Synonyms Top

Scientific name Authority First published in
Myristica superba Hook.f. & Thomson Fl. Ind. 1: 162 (1855)
Palala superba Kuntze Revis. Gen. Pl. 2: 567 (1891)

Common names Top

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Language Common/alternative name
English cabbage-leafed nutmeg
Arabic هورسفلدية جميلة
Persian هرسفیلدیا سوپربا
Malay penarahan

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000724962
Tropicos 21800232
KEW urn:lsid:ipni.org:names:585787-1
Open Tree Of Life 6028362
NCBI Taxonomy 2894227
IUCN Red List 31557
IPNI 585787-1
iNaturalist 193547
GBIF 5564975
Freebase /m/02x9w74
Wikipedia Horsfieldia_superba

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Title Authors Publication Released IDs
Aqua/Mechanochemical Mediated Synthesis of Novel Spiro [Indole–Pyrrolidine] Derivatives Salami SA, Smith VJ, Krause RW Int J Mol Sci 24-Jan-2023
PMCID:PMC9917244
doi:10.3390/ijms24032307
PMID:36768632
Efficient Synthesis of 2,3′-Spirobi (Indolin)-2′-Ones and Preliminary Evaluation of Their Damage to Mitochondria in HeLa Cells Li H, Yu Z, Sun H, Liu B, Wang X, Shao Z, Wang M, Xie W, Yao X, Yao Q, Zhi Y Front Pharmacol 23-Feb-2022
PMCID:PMC8904893
doi:10.3389/fphar.2021.821518
PMID:35280257
Recent Advances in Stereoselective Ring Expansion of Spirocyclopropanes: Access to the Spirocyclic Compounds Sarkar T, Das BK, Talukdar K, Shah TA, Punniyamurthy T ACS Omega 07-Oct-2020
PMCID:PMC7581100
doi:10.1021/acsomega.0c03856
PMID:33110959
Advances in the Asymmetric Total Synthesis of Natural Products Using Chiral Secondary Amine Catalyzed Reactions of α,β-Unsaturated Aldehydes Wang Z Molecules 19-Sep-2019
PMCID:PMC6767148
doi:10.3390/molecules24183412
PMID:31546876
Construction of Spirooxindole Skeleton Through Intramolecular Dieckmann Cyclization Wu T, Pan Z, Xia C Nat Prod Bioprospect 08-May-2017
PMCID:PMC5481276
doi:10.1007/s13659-017-0131-0
PMID:28484999
Pot economy and one-pot synthesis Hayashi Y Chem Sci 06-Jan-2016
PMCID:PMC5529999
doi:10.1039/c5sc02913a
PMID:28791118
1′-Methyl-4′-(4-methyl­phen­yl)dispiro­[indane-2,3′-pyrrolidine-2′,3′′-indoline]-1,2′′-dione Moustafa AM, Girgis AS, Shalaby SM, Tiekink ER Acta Crystallogr Sect E Struct Rep Online 23-Jun-2012
PMCID:PMC3393996
doi:10.1107/S1600536812028012
PMID:22798861
Total synthesis of (±)-coerulescine and (±)-horsfiline Kulkarni MG, Dhondge AP, Chavhan SW, Borhade AS, Shaikh YB, Birhade DR, Desai MP, Dhatrak NR Beilstein J Org Chem 27-Sep-2010
PMCID:PMC2982140
doi:10.3762/bjoc.6.103
PMID:21085515
Palladium Asymmetric Allylic Alkylation of Prochiral Nucleophiles: Horsfiline M.Trost B, Brennan MK Org Lett 11-May-2006
PMCID:PMC2565574
doi:10.1021/ol060298j
PMID:16671773
Horsfiline, an oxindole alkaloid from Horsfieldia superba Akino Jossang, Per Jossang, Hamid A. Hadi, Thierry Sevenet, Bernard Bodo American Chemical Society (ACS) 12-Mar-2005
doi:10.1021/JO00023A016

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Organoheterocyclic compounds / Indoles and derivatives / Indolines
(+)-Horsfiline 11506896 Click to see CN1CCC2(C1)C3=C(C=CC(=C3)OC)NC2=O 232.28 unknown https://doi.org/10.1021/JO00023A016
5-Methoxy-1'-methylspiro[indoline-3,3'-pyrrolidin]-2-one 11128172 Click to see CN1CCC2(C1)C3=C(C=CC(=C3)OC)NC2=O 232.28 unknown https://doi.org/10.1021/JO00023A016
Horsfiline 11042617 Click to see CN1CCC2(C1)C3=C(C=CC(=C3)OC)NC2=O 232.28 unknown https://doi.org/10.1021/JO00023A016
> Organoheterocyclic compounds / Indoles and derivatives / Pyridoindoles / Beta carbolines
6-Methoxy-2-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indole 5319717 Click to see CN1CCC2=C(C1)NC3=C2C=C(C=C3)OC 216.28 unknown https://doi.org/10.1021/JO00023A016
> Organoheterocyclic compounds / Indoles and derivatives / Tryptamines and derivatives
N,N-Dimethyl-5-methoxytryptamine 1832 Click to see CN(C)CCC1=CNC2=C1C=C(C=C2)OC 218.29 unknown https://doi.org/10.1021/JO00023A016

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