Veratrum californicum - Unknown
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Internal ID UUID644024190f85c457473187
Scientific name Veratrum californicum
Authority Durand
First published in J. Acad. Nat. Sci. Philadelphia Ser. II, iii. (1855) 103.

Description Top

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Veratrum californicum is a poisonous plant native to western North America, growing from near sea level to as high as 11,000 feet. It has an erect, unbranched, heavily leafy stem resembling a cornstalk, and many inch-wide flowers with 6 white tepals, a green center, 6 stamens, and a 3-branched pistil. It displays mast seeding, blooming during midsummer from July to August. It is a source of teratogens which can cause birth defects in animals that graze upon it.

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No known synonyms.

Common names Top

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Language Common/alternative name
English california false hellebore
Swedish jättenysrot

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Name Authority First published in
Veratrum californicum var. californicum Unknown
Veratrum californicum var. caudatum (A.Heller) C.L.Hitchc. Vasc. Pl. Pacif. N. W. 1: 809 (1969)

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

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Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000751689
USDA Plants VECA2
Tropicos 18401403
KEW urn:lsid:ipni.org:names:30327875-2
The Plant List kew-291216
Open Tree Of Life 603934
NCBI Taxonomy 50242
Nature Serve 2.160553
IPNI 543476-1
iNaturalist 60500
GBIF 2742108
Freebase /m/066sy8
EPPO VEACA
EOL 1083435
Calflora (Californian flora) 10439
USDA GRIN 41143
Wikipedia Veratrum_californicum
Nature Serve 2.958593

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Pharmacology of Veratrum californicum Alkaloids as Hedgehog Pathway Antagonists Dirks ML, McDougal OM Pharmaceuticals (Basel) 17-Jan-2024
PMCID:PMC10821092
doi:10.3390/ph17010123
PMID:38256956
Virus diversity and activity is driven by snowmelt and host dynamics in a high-altitude watershed soil ecosystem Coclet C, Sorensen PO, Karaoz U, Wang S, Brodie EL, Eloe-Fadrosh EA, Roux S Microbiome 27-Oct-2023
PMCID:PMC10604447
doi:10.1186/s40168-023-01666-z
PMID:37891627
Meningoencephalocele and supernumerary ectopic limb arising from the occipital bone in a Jacob sheep lamb Bedford S, Appleby R, Goodman L, Lack A, Castillo G Can Vet J 01-Oct-2023
PMCID:PMC10506348
PMID:37780471
Hedgehog signaling in tissue homeostasis, cancers, and targeted therapies Jing J, Wu Z, Wang J, Luo G, Lin H, Fan Y, Zhou C Signal Transduct Target Ther 18-Aug-2023
PMCID:PMC10439210
doi:10.1038/s41392-023-01559-5
PMID:37596267
Therapeutic Role of Alkaloids and Alkaloid Derivatives in Cancer Management Olofinsan K, Abrahamse H, George BP Molecules 22-Jul-2023
PMCID:PMC10386240
doi:10.3390/molecules28145578
PMID:37513450
“DEPHENCE” system—a novel regimen of therapy that is urgently needed in the high-grade serous ovarian cancer—a focus on anti-cancer stem cell and anti-tumor microenvironment targeted therapies Wilczyński JR, Wilczyński M, Paradowska E Front Oncol 28-Jun-2023
PMCID:PMC10338102
doi:10.3389/fonc.2023.1201497
PMID:37448521
Comparative transcriptome analysis of Veratrum maackii and Veratrum nigrum reveals multiple candidate genes involved in steroidal alkaloid biosynthesis Wang D, Yu Z, Guan M, Cai Q, Wei J, Ma P, Xue Z, Ma R, Oksman-Caldentey KM, Rischer H Sci Rep 21-May-2023
PMCID:PMC10200796
doi:10.1038/s41598-023-35429-5
PMID:37211560
Phytochemicals and bioactive compounds effective against acute myeloid leukemia: A systematic review Egbuna C, Patrick‐Iwuanyanwu KC, Onyeike EN, Khan J, Palai S, Patel SB, Parmar VK, Kushwaha G, Singh O, Jeevanandam J, Kumarasamy S, Uche CZ, Narayanan M, Rudrapal M, Odoh U, Chikeokwu I, Găman M, Saravanan K, Ifemeje JC, Ezzat SM, Olisah MC, Chikwendu CJ, Adedokun KA, Imodoye SO, Bello IO, Twinomuhwezi H, Awuchi CG Food Sci Nutr 15-May-2023
PMCID:PMC10345688
doi:10.1002/fsn3.3420
PMID:37457145
Steroidal saponin profiles and their key genes for synthesis and regulation in Asparagus officinalis L. by joint analysis of metabolomics and transcriptomics Cheng Q, Zeng L, Wen H, Brown SE, Wu H, Li X, Lin C, Liu Z, Mao Z BMC Plant Biol 20-Apr-2023
PMCID:PMC10116787
doi:10.1186/s12870-023-04222-x
PMID:37081391
Recent advance of herbal medicines in cancer- a molecular approach Ali M, Wani SU, Salahuddin M, S.N. M, K M, Dey T, Zargar MI, Singh J Heliyon 14-Feb-2023
PMCID:PMC9971193
doi:10.1016/j.heliyon.2023.e13684
PMID:36865478
Understanding the Roles of the Hedgehog Signaling Pathway during T-Cell Lymphopoiesis and in T-Cell Acute Lymphoblastic Leukemia (T-ALL) Martelli AM, Paganelli F, Truocchio S, Palumbo C, Chiarini F, McCubrey JA Int J Mol Sci 03-Feb-2023
PMCID:PMC9917970
doi:10.3390/ijms24032962
PMID:36769284
Transcriptome Analysis of CYP450 Family Members in Fritillaria cirrhosa D. Don and Profiling of Key CYP450s Related to Isosteroidal Alkaloid Biosynthesis Li R, Xiao M, Li J, Zhao Q, Wang M, Zhu Z Genes (Basel) 14-Jan-2023
PMCID:PMC9859280
doi:10.3390/genes14010219
PMID:36672960
3α,7-Dihydroxy-14(13→12)abeo-5β,12α(H),13β(H)-cholan-24-oic Acids Display Neuroprotective Properties in Common Forms of Parkinson’s Disease Luxenburger A, Clemmens H, Hastings C, Harris LD, Ure EM, Cameron SA, Aasly J, Bandmann O, Weymouth-Wilson A, Furneaux RH, Mortiboys H Biomolecules 30-Dec-2022
PMCID:PMC9855844
doi:10.3390/biom13010076
PMID:36671460
Cytochrome P450 monooxygenase-mediated tailoring of triterpenoids and steroids in plants Malhotra K, Franke J Beilstein J Org Chem 21-Sep-2022
PMCID:PMC9520826
doi:10.3762/bjoc.18.135
PMID:36225725
Research Status of Mouse Models for Non-Small-Cell Lung Cancer (NSCLC) and Antitumor Therapy of Traditional Chinese Medicine (TCM) in Mouse Models Chen H, Zheng M, Zhang W, Long Y, Xu Y, Yuan M Evid Based Complement Alternat Med 21-Sep-2022
PMCID:PMC9519343
doi:10.1155/2022/6404853
PMID:36185084

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Fluorenes
(2R,3S,5R)-2-[(1R)-1-[(3S,6aS,11aS,11bR)-3-hydroxy-10,11b-dimethyl-1,2,3,4,6,6a,11,11a-octahydrobenzo[a]fluoren-9-yl]ethyl]-5-methylpiperidin-3-ol 163011773 Click to see CC1CC(C(NC1)C(C)C2=C(C3=C(C=C2)C4CC=C5CC(CCC5(C4C3)C)O)C)O 409.60 unknown https://doi.org/10.1016/S0031-9422(00)86328-1
14,15,16,17-Tetradehydroveratraman-3,23-diol 229854 Click to see CC1CC(C(NC1)C(C)C2=C(C3=C(C=C2)C4CC=C5CC(CCC5(C4C3)C)O)C)O 409.60 unknown https://doi.org/10.1016/S0031-9422(00)86328-1
Veratramine 6070 Click to see CC1CC(C(NC1)C(C)C2=C(C3=C(C=C2)C4CC=C5CC(CCC5(C4C3)C)O)C)O 409.60 unknown https://doi.org/10.1016/S0378-4347(00)85143-9
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal alkaloids / Jerveratrum-type alkaloids
3',6',10,11b-tetramethylspiro[2,3,4,6,6a,6b,7,8,11,11a-decahydro-1H-benzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-3-ol 4113848 Click to see CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5CC4=C3C)C)O)C)NC1 411.60 unknown https://doi.org/10.1016/S0039-128X(69)80012-7
Cyclopamine 442972 Click to see CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5CC4=C3C)C)O)C)NC1 411.60 unknown https://doi.org/10.1016/S0378-4347(00)85143-9
https://doi.org/10.1016/S0039-128X(69)80012-7
Jervine 10098 Click to see CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5C(=O)C4=C3C)C)O)C)NC1 425.60 unknown https://doi.org/10.1016/S0378-4347(00)85143-9
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal alkaloids / Solanidines and derivatives
Rubijervine 253295 Click to see CC1CCC2C(C3C(N2C1)CC4C3(C(CC5C4CC=C6C5(CCC(C6)O)C)O)C)C 413.60 unknown https://doi.org/10.1016/0031-9422(74)85061-2
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal glycosides / Steroidal saponins
11-Deoxojervinebeta-D-glucoside 31678 Click to see CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5CC4=C3C)C)OC7C(C(C(C(O7)CO)O)O)O)C)NC1 573.80 unknown https://doi.org/10.1016/S0039-128X(69)80012-7
Cycloposine 25078000 Click to see CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5CC4=C3C)C)OC7C(C(C(C(O7)CO)O)O)O)C)NC1 573.80 unknown https://doi.org/10.1016/S0039-128X(69)80012-7

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