Veratrum album
Details Top
| Internal ID | UUID64402419bd719258378306 |
| Scientific name | Veratrum album |
| Authority | L. |
| First published in | Sp. Pl. : 1044 (1753) |
Ethnobotanical Use Top
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Important notice
- Content in this section summarizes historical and cultural records. It is not medical advice.
- Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
- Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
- Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.
Veratrum album (L.) is a tall, white-flowered member of the family Melanthiaceae whose rhizomes and roots have been used in homeopathy for several centuries. In European materia medica, the dried root is first processed as a mother tincture and then serially diluted and succussed to produce classical potencies used mainly in short courses for acute “shock” or sudden diarrheal complaints (Hahnemann, 1842; Boiron, 2016). In 19th‑century European materia medica, very weak decoctions of the root were listed historically as diaphoretic and emetic agents; the same texts emphasized that even at low dilutions the drug was strongly emetic, with narrow safety margins, and noted that it was sometimes mixed with ipecac (bark of Cephaelis ipecacuanha) (Ellingwood, 1919). Outside homeopathy, the dried root is used in Russian folk practice as an insecticide against lice, fleas, and in beekeeping; the powdered root is mixed into hives to induce sedative “fumigation” effects in bees (Trease and Evans, 2009; Konstantinova et al., 2004). The same approach is found in North American beekeeping and in Moldavian ethnobotany, where the powdered root is dusted into nests or hives for bee restraint (Clapham et al., 1952; Baranov, 1971). Across these contexts the plant parts used are the underground rhizomes and roots; preparations range from tinctures and very dilute decoctions (homeopathy/herbal) to powders for external application.
A concise practical example is a mother tincture suitable for homeopathic use: place 1 part dried Veratrum album root/rhizome by weight in 10 parts 45% ethanol, macerate in a dark bottle at room temperature for 4–6 weeks, shaking daily, then press and filter; this 1:10 (w/v) tincture is then succussed to produce the desired potency for homeopathic use. For a non-homeopathic decoction, no dose should be attempted without professional supervision because the plant is a Class‑1 poison; when prepared historically the weak decoction was administered by qualified practitioners in limited doses solely as an emetic/diaphoretic, with emphatic warnings to stop if vomiting or excessive salivation appears (Ellingwood, 1919). Powdered root is applied to hives in small measured amounts to avoid over‑exposure to bees and must be stored out of reach of children (Konstantinova et al., 2004).
The activity of the dried rhizomes and roots rests on well‑known Veratrum alkaloids, notably protoveratrines, jervine, cyclopamine, and cevadine, which act as sodium channel activators (veratridine‑like effect) in excitable cells, together with hypotensive actions mediated via autonomic ganglia (Bruneton, 1999; Tyler et al., 1992). These steroidal alkaloids underwrite both the historic emetic/diaphoretic actions of weak decoctions in European materia medica and the sedative/insecticidal effects reported in homeopathic tinctures and in beekeeping uses across Europe and North America.
Today Veratrum album remains available as a homeopathic mother tincture (BP/EP compliance) through homeopathic pharmacies and in powdered form through veterinary and beekeeping suppliers, while research continues to focus on pharmacology of individual alkaloids rather than the whole plant in its traditional forms.
General Uses Top
Suggest a correction!Industrial and craft applications:
- The root and rhizome of Veratrum album are the primary commercial source of steroidal alkaloids such as veratridine and jervine. These compounds are employed as pharmacological tools in electrophysiology and neurobiology, acting as agonists of voltage‑gated sodium channels to dissect ion‑channel function.
- Crude extracts or purified alkaloids have been investigated for insecticidal activity and are cited in the literature as natural pesticide candidates. Their mode of action involves disruption of insect nervous‑system signaling, making them potential leads for bio‑insecticide formulation.
- The plant serves as a reference material for the standardization of alkaloid analysis; certified reference materials are available for quantifying veratridine in botanical extracts.
- Alkaloid fractions from V. album are also used as raw material for the semi‑synthetic preparation of analogues employed in structure–activity relationship studies.
Properties relevant to use:
- The main bioactive constituents are polyhydroxylated steroidal alkaloids (e.g., veratridine, jervine) that are highly lipophilic, readily extractable with organic solvents such as methanol or chloroform, and exhibit characteristic UV absorption maxima near 210–230 nm.
- Their potency as sodium‑channel agonists is due to specific structural features, including an unsaturated C‑ring and multiple hydroxyl groups, which confer strong binding affinity and low water solubility.
- The alkaloid profile is stable under controlled laboratory conditions but degrades under prolonged exposure to light and elevated temperature.
Standards and regulation:
- Veratrum album is classified as a poisonous plant under the EU Directive on the Classification, Labelling and Packaging of Substances and Mixtures, as well as national plant‑toxin regulations in many countries. Handling, storage, and distribution require appropriate licences and hazard‑communication labels (e.g., GHS pictogram GHS06).
- Analytical protocols for veratridine quantification are covered by ISO 15918 (Botanical toxins – Determination of steroidal alkaloids by LC‑MS/MS). Certified reference materials conforming to this standard are commercially available.
- Use of the plant material in pesticide research must comply with national and regional biopesticide registration guidelines, which often mandate toxicity and environmental‑fate studies.
Sustainability and sourcing:
- The species is a perennial herb found in alpine and sub‑alpine meadows of Europe and Asia. Wild populations are limited, and over‑harvesting poses conservation concerns in several European jurisdictions (e.g., the Berne Convention on the Conservation of European Wildlife and Natural Habitats).
- Small‑scale cultivation for research purposes can be achieved through controlled propagation of rhizome cuttings, with harvest cycles of 2–3 years to allow regeneration of the underground organs.
- Sustainable harvesting practices include limiting collection to no more than 10 % of a population per year, monitoring of stand density, and adherence to local permits.
Synonyms Top
| Scientific name | Authority | First published in |
|---|---|---|
| Helleborus albus | (L.) Gueldenst. | Reis. Russland (Gueldenst.) ii. 196 (1791). |
| Melanthium virens | Thunb. | Melanthio : 4 (1797) |
| Melanthium bracteolare | Desr. | Encycl. 4: 25 (1797) |
| Melanthium album | Thunb. | Melanthio : 8 (1797) |
| Veratrum lobelianum f. oppositifolium | Cheshm. | Fitologiya 7: 75 (1977) |
| Veratrum album subsp. misae | (Sirj.) Tzvelev | Fl. Evropeískoí Chasti SSSR 4: 210 (1979) |
| Veratrum album f. glabrescens | (Zapat) Soó | Acta Bot. Acad. Sci. Hung. 16: 365 (1970 publ. 1971) |
| Veratrum lobelianum subsp. misae | (Širj.) Šourková | Novit. Bot. Univ. Carol. 1988(4): 65. |
| Veratrum album f. podolicum | (Zapat) Soó | Acta Bot. Acad. Sci. Hung. 16: 365 (1970 publ. 1971) |
| Veratrum croaticum | O.Loes. | Verh. Bot. Vereins Prov. Brandenburg 68: 133 (1926) |
| Veratrum flavum | O.Loes. | Verh. Bot. Vereins Prov. Brandenburg 68: 133 (1926) |
| Veratrum bosniacum | Beck | Ann. K. K. Naturhist. Hofmus. 2: 50 (1887) |
| Veratrum polygamum | Gilib. | Exerc. Phyt. 2: 463 (1792) |
| Veratrum misae | O.Loes. | Repert. Spec. Nov. Regni Veg. 24: 65 (1927) |
| Veratrum album var. misae | Širj. | Acta Bot. Bohem. 2: 41. 1923 |
| Veratrum lobelianum var. glabrescens | Zapal. | Consp. Fl. Gallic. Crit. 1: 173. 1906 |
| Veratrum lobelianum var. podolicum | Zapal. | Consp. Fl. Gallic. Crit. 1: 173. 1906 |
| Veratrum album var. spathulatum | Beck | Fl. Nieder-Osterreich 177. 1890 |
| Veratrum album var. flavum | Griseb. | Spic. Fl. Rumel. 2: 381. 1844 |
| Veratrum album var. croaticum | Beck | Glasn. Zemaljsk. Muz. Bosni Hercegovini 15: 200. 1903 |
| Veratrum bosniacum var. albanicum | O.Loes. | Repert. Spec. Nov. Regni Veg. 24: 62. 1927 |
| Veratrum lobelianum var. misae | (Širj.) O.Loes. | Verh. Bot. Vereins Prov. Brandenburg 68: 132 1926 |
| Veratrum album var. viride | Lapeyr. | Hist. Pl. Pyrenées 611. 1813 |
| Veratrum album var. viridiflorum | Mert. & W.D.J.Koch | Deutschl. Fl. ed. 3, 2: 625. 1826 |
| Veratrum lobelianum var. obovatum | Beck | Glasn. Zemaljsk. Muz. Bosni Hercegovini 15: 200. 1903 |
| Veratrum album var. bosniacum | (Beck) Nyman | Consp. Fl. Eur. Suppl. 2: 311. 1890 |
| Veratrum album subsp. albicans | Gaudin | Fl. Helv. 6: 311 (1830) |
| Veratrum viride | Röhl. | Deutschl. Fl. ed. 2, 2: 237 (1812) |
| Veratrum parviflorum | Bong. | Mém. Acad. Imp. Sci. St.-Pétersbourg Divers Savans 2: 166 (1835) |
| Veratrum album var. albiflorum | Lange | Prodr. Fl. Hispan. 1: 192 (1861) |
| Veratrum album f. viridiflorum | (Mert. & W.D.J.Koch) Wimm. & Grab. | Fl. Siles. 1: 353 (1827) |
| Veratrum album var. lobelianum | (Bernh.) Rchb. | Fl. Germ. Excurs. 3: X (1833) |
Common names Top
Add a new one! Suggest a correction!| Language | Common/alternative name |
|---|---|
| English | european white hellebore |
| English | white false-helleborine |
| English | white-hellebore |
| English | white veratrum |
| English | white hellebore |
| English | false helleborine |
| English | european white-hellebore |
| English | white false hellebore |
| Spanish | veratrum bosniacum |
| Spanish | hierba de ballesteros |
| Spanish | hierba ballestera |
| Spanish | heléboro blanco |
| Spanish | eléboro blanco |
| Spanish | eléboro |
| Spanish | belegambre |
| Spanish | veratrum lobelianum var. glabrescens |
| Spanish | hierba del ballestero |
| Spanish | veratrum lobelianum subsp. misae |
| Spanish | helleborus albus |
| Spanish | ballestera blanca |
| Spanish | ballestera |
| Spanish | baladro |
| Spanish | baladra |
| Spanish | vedegambre |
| Spanish | yerba del ballestero |
| Spanish | osurba |
| Spanish | rizoma de veratro |
| Spanish | surbia |
| Spanish | veratrum lobelianum var. obovatum |
| Spanish | veratrum lobelianum var. podolicum |
| Spanish | survia |
| Spanish | vedegambre blanco |
| Spanish | verdegambre blanco |
| Spanish | yerba ballestera blanca |
| Spanish | yerba de ballesteros |
| Spanish | yerba de ballesteros blanca |
| Spanish | veratrum polygamum |
| Spanish | verdegambre |
| Spanish | heleboro blanco |
| Arabic | خربوق أبيض |
| Arabic | خربق |
| Azerbaijani | ağ asırqal |
| Catalan | veladre |
| Catalan | veratre |
| Czech | kýchavice bílá |
| Danish | hvid foldblad |
| German | lauskraut |
| German | läusewurzel |
| German | nieswurz |
| German | weißer germer |
| Greek | Βέρατρον το λευκόν |
| Esperanto | blanka heleboro |
| Persian | وراتروم آلبوم |
| Finnish | valkopärskäjuuri |
| Finnish | pohjanpärskäjuuri |
| French | vérine |
| French | faux hellébore |
| French | hellébore blanc |
| French | varaire |
| French | véraire |
| French | vératre blanc |
| French | vérâtre blanc |
| Galician | surbia |
| Hebrew | וורטרום לבן |
| Upper Sorbian | běła kichawa |
| Hungarian | fehér zászpa |
| Armenian | Կեղծ ղանձլամեր սպիտակ |
| Icelandic | hnerrarót |
| Italian | veratro |
| Japanese | 梅蕙草 |
| Japanese | バイケイソウ |
| Korean | 박새 (식물) |
| Lithuanian | lobelio čemerys |
| Macedonian | Чемерика |
| Norwegian Bokmål | nyserot |
| Dutch | witte nieswortel |
| Dutch | wit nieskruid |
| Dutch | dodenwaad |
| Norwegian Nynorsk | kvit nyserot |
| os | Нæлгæндыс |
| Polish | ciemierzyca biała |
| Polish | ciemiężyca biała |
| Russian | Чемерица белая |
| Slovak | kýchavica biela |
| Slovenian | bela čmerika |
| Swedish | vit nysrot |
| Turkish | ak çöpleme |
| Ukrainian | Чемериця біла |
| Chinese | 白藜蘆 |
| Chinese | 白藜芦 |
Germination/Propagation Top
Suggest a correction or add new data!| Requires Soaking: These seeds need to be soaked in warm water until they swell, which can take 24-48 hours. Seeds that float are usually not viable and should be discarded, along with the soaking water. |
| seed very poisonous, wash hands after handling, 20°C x 4 weeks, then -7°C x 6 weeks, then 10°C |
Distribution (via POWO/KEW) Top
Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
-
Asia-temperate click to expand
-
Caucasus
- Transcaucasus
-
Russian Far East
- Magadan
-
Siberia
- Krasnoyarsk
- West Siberia
- Yakutskiya
-
Western Asia
- Turkey
-
Caucasus
-
Europe click to expand
-
Eastern Europe
- Baltic States
- Belarus
- Central European Russia
- East European Russia
- North European Russia
- South European Russia
- Ukraine
-
Middle Europe
- Austria
- Czechoslovakia
- Germany
- Hungary
- Poland
- Switzerland
-
Northern Europe
- Finland
- Norway
-
Southeastern Europe
- Albania
- Italy
- Romania
- Yugoslavia
-
Southwestern Europe
- France
- Portugal
- Spain
-
Eastern Europe
Links to other databases Top
Suggest others/fix!| Database | ID/link to page |
|---|---|
| World Flora Online | wfo-0000751720 |
| UNII | 7DEL4FSK0E |
| USDA Plants | VEAL3 |
| Tropicos | 18400825 |
| INPN | 128520 |
| Flora of Italy | 6743 |
| KEW | urn:lsid:ipni.org:names:30192264-2 |
| The Plant List | kew-291244 |
| PFAF | Veratrum album |
| Open Tree Of Life | 603938 |
| Observations.org | 123316 |
| NCBI Taxonomy | 50243 |
| Nature Serve | 2.133824 |
| IPNI | 30192264-2 |
| iNaturalist | 85424 |
| GBIF | 2742119 |
| Freebase | /m/02qdtcr |
| EPPO | VEAAL |
| EOL | 1083440 |
| USDA GRIN | 41134 |
| Wikipedia | Veratrum_album |
Genomes (via NCBI) Top
No reference genome is available on NCBI yet. We are constantly monitoring for new data.
Scientific Literature Top
Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
If you wish to see all the related articles click here.
Phytochemical Profile Top
Add a new one!
Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.
You can also contribute to this by clicking here.
| Name | PubChem ID | Canonical SMILES | MW | Found in | Proof |
|---|---|---|---|---|---|
| > Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Branched fatty acids / Methyl-branched fatty acids | |||||
| (R)-2-Methylbutanoic acid | 6950479 | Click to see CCC(C)C(=O)O | 102.13 | unknown | https://doi.org/10.1002/ARDP.19372750803 |
| 2-Methylbutanoic Acid | 8314 | Click to see | 102.13 | unknown | https://doi.org/10.1002/ARDP.19372750803 |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Hydroxysteroids / 3-hydroxysteroids / 3-beta-hydroxysteroids | |||||
| (1R,2S,4R,5'R,6S,7S,8S,12S,13R,16S)-5',7,8,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-9,18-diene-6,2'-piperidine]-16-ol | 162976108 | Click to see | 411.60 | unknown | https://doi.org/10.1016/S0040-4039(00)75638-3 |
| Veramine | 12444728 | Click to see | 411.60 | unknown | https://doi.org/10.1016/0031-9422(96)00211-7 |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Hydroxysteroids / 3-hydroxysteroids / 3-hydroxy delta-5-steroids | |||||
| 5',7,8,13-Tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-9,18-diene-6,2'-piperidine]-16-ol | 12444727 | Click to see CC1CCC2(C(C3(C(O2)CC4C3=CCC5C4CC=C6C5(CCC(C6)O)C)C)C)NC1 | 411.60 | unknown | https://doi.org/10.1016/S0040-4039(00)75638-3 |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Pregnane steroids / Gluco/mineralocorticoids, progestogins and derivatives | |||||
| (3S,8R,9R,10S,13S,14R,17S)-10,13-dimethyl-17-[(1S)-1-[(2S)-5-methyl-3,4-dihydro-2H-pyrrol-2-yl]ethyl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol | 162892386 | Click to see | 383.60 | unknown | https://doi.org/10.1016/S0040-4039(01)97086-8 |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroid esters | |||||
| [17-[1-(3-Hydroxy-5-methyl-2-pyridinyl)ethyl]-10,13-dimethyl-6-oxo-1,2,3,4,5,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl] acetate | 162879530 | Click to see | 467.60 | unknown | https://doi.org/10.1007/BF01167577 |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal alkaloids / 22,26-epiminocholestanes | |||||
| (20S,25S)-22,26-iminocholesta-5,22(N)-dien-3beta-ol | 70699389 | Click to see | 397.60 | unknown | https://doi.org/10.1007/BF00564623 |
| (3S,8S,9R,10R,13R,14S,17S)-10,13-dimethyl-17-[(1S)-1-[(2S,5R)-5-methylpiperidin-2-yl]ethyl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol | 162965147 | Click to see CC1CCC(NC1)C(C)C2CCC3C2(CCC4C3CC=C5C4(CCC(C5)O)C)C | 399.70 | unknown | https://doi.org/10.1135/CCCC19773643 |
| 16,28-Secosolanid-5-en-3-ol, (3beta)- | 566870 | Click to see CC1CCC(NC1)C(C)C2CCC3C2(CCC4C3CC=C5C4(CCC(C5)O)C)C | 399.70 | unknown | https://doi.org/10.1135/CCCC19773643 |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal alkaloids / Cerveratrum-type alkaloids | |||||
| (10,12,13,14,16,23-Hexahydroxy-6,10,19-trimethyl-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-22-yl) 2-methylbutanoate | 12314631 | Click to see CCC(C)C(=O)OC1CCC2(C3C1(OC24CC5C6CN7CC(CCC7C(C6C(C(C5(C4C(C3)O)O)O)O)(C)O)C)O)C | 593.70 | unknown |
https://doi.org/10.1002/ARDP.19372750803 https://doi.org/10.1002/ARDP.18902280906 |
| (16,22-Diacetyloxy-10,12,14,23-tetrahydroxy-6,10,19-trimethyl-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-13-yl) 2-methylbutanoate | 12305686 | Click to see | 677.80 | unknown | https://doi.org/10.1021/JA01115A015 |
| [(1S,2S,6S,9S,10S,11R,12R,13S,14S,15S,16R,18S,19R,20S,22S,23S,25R)-20-acetyloxy-10,12,14,16,23-pentahydroxy-6,10,19-trimethyl-13-[(2R)-2-methylbutanoyl]oxy-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-22-yl] 2,2-dimethylbutanoate | 162887174 | Click to see | 749.90 | unknown | https://doi.org/10.1016/0031-9422(96)00211-7 |
| [(1S,2S,6S,9S,10S,11R,12R,13S,14S,15S,16R,18S,19R,20S,22S,23S,25R)-20-acetyloxy-10,12,14,16,23-pentahydroxy-6,10,19-trimethyl-13-[(2S)-2-methylbutanoyl]oxy-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-22-yl] (2S)-2-hydroxy-2-methylbutanoate | 162820080 | Click to see CCC(C)C(=O)OC1C(C2C(CN3CC(CCC3C2(C)O)C)C4C1(C5C(CC6C7(C5(C4)OC6(C(CC7OC(=O)C)OC(=O)C(C)(CC)O)O)C)O)O)O | 751.90 | unknown | https://doi.org/10.1016/0031-9422(96)00211-7 |
| [(1S,2S,6S,9S,10S,11R,12R,13S,14S,15S,16R,18S,19S,22S,23S,25R)-10,12,13,14,16,23-hexahydroxy-6,10,19-trimethyl-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-22-yl] (2R)-2-methylbutanoate | 163018240 | Click to see | 593.70 | unknown |
https://doi.org/10.1002/ARDP.19372750803 https://doi.org/10.1002/ARDP.18902280906 |
| [(1S,2S,6S,9S,10S,11R,12R,13S,14S,15S,16R,18S,19S,22S,23S,25R)-10,12,14,16,23-pentahydroxy-6,10,19-trimethyl-13-[(2R)-2-methylbutanoyl]oxy-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-22-yl] (2S)-2-hydroxy-2-methylbutanoate | 163194108 | Click to see | 693.90 | unknown |
https://doi.org/10.1002/ARDP.19552881005 https://doi.org/10.1002/ARDP.19372750803 |
| [(1S,2S,6S,9S,10S,11R,12R,13S,14S,15S,16R,18S,19S,22S,23S,25R)-16-acetyloxy-10,12,14,23-tetrahydroxy-6,10,19-trimethyl-13-[(2R)-2-methylbutanoyl]oxy-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-22-yl] (2S,3S)-3-acetyloxy-2-hydroxy-2-methylbutanoate | 163008235 | Click to see | 793.90 | unknown |
https://doi.org/10.1021/JA01115A015 https://doi.org/10.1021/JA01104A047 |
| [(1S,2S,6S,9S,10S,11R,12R,13S,14S,15S,16R,18S,19S,22S,23S,25R)-16-acetyloxy-10,12,14,23-tetrahydroxy-6,10,19-trimethyl-13-[(2R)-2-methylbutanoyl]oxy-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-22-yl] 3,4-dimethoxybenzoate | 162971633 | Click to see | 799.90 | unknown | https://doi.org/10.1021/NP50083A002 |
| [(1S,2S,6S,9S,10S,11R,12R,13S,14S,15S,16R,18S,19S,22S,23S,25R)-16-acetyloxy-10,12,14,23-tetrahydroxy-6,10,19-trimethyl-22-[(Z)-2-methylbut-2-enoyl]oxy-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-13-yl] (2R)-2-methylbutanoate | 101306698 | Click to see CCC(C)C(=O)OC1C(C2C(CN3CC(CCC3C2(C)O)C)C4C1(C5C(CC6C7(C5(C4)OC6(C(CC7)OC(=O)C(=CC)C)O)C)OC(=O)C)O)O | 717.90 | unknown | https://doi.org/10.1007/BF00567932 |
| [(1S,2S,6S,9S,11R,12R,13S,14S,15S,16R,18S,19S,22S,23S,25R)-10,12,14,16,23-pentahydroxy-6,10,19-trimethyl-13-[(2R)-2-methylbutanoyl]oxy-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-22-yl] (2R,3R)-2,3-dihydroxy-2-methylbutanoate | 101281380 | Click to see CCC(C)C(=O)OC1C(C2C(CN3CC(CCC3C2(C)O)C)C4C1(C5C(CC6C7(C5(C4)OC6(C(CC7)OC(=O)C(C)(C(C)O)O)O)C)O)O)O | 709.90 | unknown | https://doi.org/10.1007/BF00566829 |
| [(1S,2S,6S,9S,11R,12R,13S,14S,15S,16R,18S,19S,22S,23S,25R)-10,12,14,16,23-pentahydroxy-6,10,19-trimethyl-13-[(2R)-2-methylbutanoyl]oxy-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-22-yl] (2S)-2-hydroxy-2-methylbutanoate | 101277305 | Click to see CCC(C)C(=O)OC1C(C2C(CN3CC(CCC3C2(C)O)C)C4C1(C5C(CC6C7(C5(C4)OC6(C(CC7)OC(=O)C(C)(CC)O)O)C)O)O)O | 693.90 | unknown | https://doi.org/10.1007/BF00564623 |
| [10,12,14,16,23-Pentahydroxy-6,10,19-trimethyl-13-(2-methylbutanoyloxy)-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-22-yl] 2-hydroxy-2-methylbutanoate | 78410929 | Click to see CCC(C)C(=O)OC1C(C2C(CN3CC(CCC3C2(C)O)C)C4C1(C5C(CC6C7(C5(C4)OC6(C(CC7)OC(=O)C(C)(CC)O)O)C)O)O)O | 693.90 | unknown | https://doi.org/10.1002/ARDP.19372750803 |
| [20-Acetyloxy-10,12,14,16,23-pentahydroxy-6,10,19-trimethyl-13-(2-methylbutanoyloxy)-24-oxa-4-azaheptacyclo[12.12.0.02,11.04,9.015,25.018,23.019,25]hexacosan-22-yl] 2,2-dimethylbutanoate | 162887173 | Click to see CCC(C)C(=O)OC1C(C2C(CN3CC(CCC3C2(C)O)C)C4C1(C5C(CC6C7(C5(C4)OC6(C(CC7OC(=O)C)OC(=O)C(C)(C)CC)O)C)O)O)O | 749.90 | unknown | https://doi.org/10.1016/0031-9422(96)00211-7 |
| 4alpha,9-Epoxycevane-3beta,4,7alpha,14,15alpha,16beta,20-heptol 7-acetate 3-[(2S,3R)-3-acetoxy-2-hydroxy-2-methylbutanoate]15-[(R)-2-methylbutanoate] | 3304506 | Click to see | 793.90 | unknown |
https://doi.org/10.1021/JA01115A015 https://doi.org/10.1021/JA01104A047 |
| 7-Deoxygermine | 409814 | Click to see | 509.60 | unknown |
https://doi.org/10.1002/ARDP.19542870610 https://doi.org/10.1002/ARDP.19442820109 |
| Cevane-3,4,14,15,16,20-hexol, 4,9-epoxy-, 3-(3,4-dimethoxybenzoate), (3beta,4alpha,15alpha,16beta)- | 162954883 | Click to see CC1CCC2C(C3C(CN2C1)C4CC56C(C4(C(C3O)O)O)CCC7C5(CCC(C7(O6)O)OC(=O)C8=CC(=C(C=C8)OC)OC)C)(C)O | 657.80 | unknown |
https://doi.org/10.1002/HLCA.19530360645 https://doi.org/10.1248/YAKUSHI1947.79.5_609 https://doi.org/10.1002/ARDP.19552881005 |
| Germinaline | 3403655 | Click to see | 751.90 | unknown | https://doi.org/10.1007/BF01167577 |
| Germinalinine | 101286251 | Click to see CCC(C)C(=O)OC1C(C2C(CN3CC(CCC3C2(C)O)C)C4C1(C5C(CC6C7(C5(C4)OC6(C(CC7)OC(=O)C(C)(C(C)O)O)O)C)OC(=O)C)O)O | 751.90 | unknown | https://doi.org/10.1007/BF00566829 |
| Germine | 442976 | Click to see CC1CCC2C(C3C(CN2C1)C4CC56C(C4(C(C3O)O)O)C(CC7C5(CCC(C7(O6)O)O)C)O)(C)O | 509.60 | unknown |
https://doi.org/10.1002/ARDP.19542870610 https://doi.org/10.1002/ARDP.19442820109 |
| Neogermitrine | 91799750 | Click to see | 677.80 | unknown | https://doi.org/10.1021/JA01115A015 |
| Neojerminalanine | 102247145 | Click to see | 751.90 | unknown | https://doi.org/10.1016/0031-9422(96)00211-7 |
| Protoveratrine | 4974 | Click to see CCC(C)C(=O)OC1C(C2C(CN3CC(CCC3C2(C)O)C)C4C1(C5C(C(C6C7(C5(C4)OC6(C(CC7)OC(=O)C(C)(CC)O)O)C)OC(=O)C)OC(=O)C)O)O | 793.90 | unknown |
https://doi.org/10.1002/ARDP.19372750803 https://doi.org/10.1002/ARDP.18902280906 |
| protoveratrine A | 8931 | Click to see CCC(C)C(=O)OC1C(C2C(CN3CC(CCC3C2(C)O)C)C4C1(C5C(C(C6C7(C5(C4)OC6(C(CC7)OC(=O)C(C)(CC)O)O)C)OC(=O)C)OC(=O)C)O)O | 793.90 | unknown |
https://doi.org/10.1007/BF00567976 https://doi.org/10.1002/ARDP.19372750803 https://doi.org/10.1002/ARDP.18902280906 https://doi.org/10.1007/BF00564106 |
| Verabenzoamine | 21672145 | Click to see CCC(C)C(=O)OC1C(C2C(CN3CC(CCC3C2(C)O)C)C4C1(C5C(CC6C7(C5(C4)OC6(C(CC7)OC(=O)C8=CC(=C(C=C8)OC)OC)O)C)O)O)O | 757.90 | unknown | https://doi.org/10.1021/NP50083A002 |
| Veratroylzygadenine | 5171637 | Click to see | 657.80 | unknown |
https://doi.org/10.1002/HLCA.19530360645 https://doi.org/10.1007/BF00564623 https://doi.org/10.1248/YAKUSHI1947.79.5_609 https://doi.org/10.1002/ARDP.19552881005 |
| Zygacin | 574506 | Click to see CC1CCC2C(C3C(CN2C1)C4CC56C(C4(C(C3O)O)O)CCC7C5(CCC(C7(O6)O)OC(=O)C)C)(C)O | 535.70 | unknown |
https://doi.org/10.1248/YAKUSHI1947.79.5_609 https://doi.org/10.1248/YAKUSHI1947.79.5_615 |
| Zygacine | 21573746 | Click to see | 535.70 | unknown |
https://doi.org/10.1248/YAKUSHI1947.79.5_609 https://doi.org/10.1248/YAKUSHI1947.79.5_615 |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal alkaloids / Jerveratrum-type alkaloids | |||||
| (+)-Jervinone | 6712079 | Click to see | 423.60 | unknown | https://doi.org/10.1021/NP50083A002 |
| (1R,3S,3'R,3'aS,5S,6'S,6aS,6bS,7'aR,9R,11aS,11bS)-1,3,5-trihydroxy-3',6',10,11b-tetramethylspiro[1,2,3,4,4a,5,6,6a,6b,7,8,11a-dodecahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-11-one | 101897906 | Click to see CC1CC2C(C(C3(O2)CCC4C5CC(C6CC(CC(C6(C5C(=O)C4=C3C)C)O)O)O)C)NC1 | 459.60 | unknown |
https://doi.org/10.1007/BF00580031 https://doi.org/10.1007/BF00575783 |
| (3',6',10,11b-tetramethyl-11-oxospiro[1,2,3,4,6,6a,6b,7,8,11a-decahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-3-yl) acetate | 272887 | Click to see | 467.60 | unknown |
https://doi.org/10.1016/0031-9422(91)84161-K https://doi.org/10.1055/S-2006-959767 |
| (3S,3'R,3'aS,6'S,6aS,6bR,7'aR,9R,11aS,11bR)-3-hydroxy-3',6',10,11b-tetramethylspiro[1,2,3,4,6,6a,6b,7,8,11a-decahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-11-one | 162903886 | Click to see | 425.60 | unknown | https://doi.org/10.1016/0031-9422(91)84161-K |
| (3S,3'R,3'aS,6'S,6aS,6bS,7'aR,9R,11R,11aS,11bR)-3',6',10,11b-tetramethylspiro[2,3,4,6,6a,6b,7,8,11,11a-decahydro-1H-benzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-3,11-diol | 102093844 | Click to see | 427.60 | unknown | https://doi.org/10.1002/HLCA.19550380736 |
| [(3S,3'R,3'aS,6'S,6aS,6bR,7'aR,9R,11aS,11bR)-3',6',10,11b-tetramethyl-11-oxospiro[1,2,3,4,6,6a,6b,7,8,11a-decahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-3-yl] acetate | 162979981 | Click to see | 467.60 | unknown | https://doi.org/10.1016/0031-9422(91)84161-K |
| 1,3-dihydroxy-3',6',10,11b-tetramethylspiro[1,2,3,4,4a,5,6,6a,6b,7,8,11a-dodecahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-11-one | 73311014 | Click to see CC1CC2C(C(C3(O2)CCC4C5CCC6CC(CC(C6(C5C(=O)C4=C3C)C)O)O)C)NC1 | 443.60 | unknown | https://doi.org/10.1055/S-2006-959767 |
| 3',6',10,11b-tetramethylspiro[2,3,4,6,6a,6b,7,8,11,11a-decahydro-1H-benzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-3,11-diol | 12444737 | Click to see CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5C(C4=C3C)O)C)O)C)NC1 | 427.60 | unknown | https://doi.org/10.1002/HLCA.19550380736 |
| 3',6',10,11b-tetramethylspiro[2,5,6,6a,6b,7,8,11a-octahydro-1H-benzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-3,11-dione | 3508283 | Click to see CC1CC2C(C(C3(O2)CCC4C5CCC6=CC(=O)CCC6(C5C(=O)C4=C3C)C)C)NC1 | 423.60 | unknown | https://doi.org/10.1055/S-2006-959767 |
| Iervin | 222153 | Click to see | 425.60 | unknown |
https://doi.org/10.1016/0031-9422(91)84161-K https://doi.org/10.1002/ARDP.18902280906 https://doi.org/10.1039/CT8793500405 https://doi.org/10.1248/YAKUSHI1947.79.8_1102 https://doi.org/10.1002/ARDP.19372750803 https://doi.org/10.1002/ARDP.19552881005 |
| Jervine | 10098 | Click to see CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5C(=O)C4=C3C)C)O)C)NC1 | 425.60 | unknown |
https://doi.org/10.1039/CT8793500405 https://doi.org/10.1002/ARDP.19552881005 https://doi.org/10.1002/ARDP.18902280906 https://doi.org/10.1248/YAKUSHI1947.79.8_1102 https://doi.org/10.1002/ARDP.19372750803 https://doi.org/10.1016/0031-9422(91)84161-K https://doi.org/10.1007/BF00580930 https://doi.org/10.1007/BF00567974 |
| Jervinone | 637157 | Click to see | 423.60 | unknown |
https://doi.org/10.1021/NP50083A002 https://doi.org/10.1055/S-2006-959767 |
| Methyl 3-(3-hydroxy-3',6',10,11b-tetramethyl-11-oxospiro[1,2,3,4,6,6a,6b,7,8,11a-decahydrobenzo[a]fluorene-9,2'-3,3a,5,6,7,7a-hexahydrofuro[3,2-b]pyridine]-4'-yl)propanoate | 14804160 | Click to see | 511.70 | unknown | https://doi.org/10.1016/0031-9422(91)84161-K |
| methyl 3-[(3S,3'R,3'aS,6'S,6aS,6bR,7'aR,9R,11aS,11bR)-3-hydroxy-3',6',10,11b-tetramethyl-11-oxospiro[1,2,3,4,6,6a,6b,7,8,11a-decahydrobenzo[a]fluorene-9,2'-3,3a,5,6,7,7a-hexahydrofuro[3,2-b]pyridine]-4'-yl]propanoate | 162938052 | Click to see | 511.70 | unknown | https://doi.org/10.1016/0031-9422(91)84161-K |
| O-Acetyljervine | 3032629 | Click to see | 467.60 | unknown |
https://doi.org/10.1016/0031-9422(91)84161-K https://doi.org/10.1055/S-2006-959767 |
| Veratvirine | 76320394 | Click to see | 443.60 | unknown | https://doi.org/10.1055/S-2006-959767 |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal alkaloids / Solanidines and derivatives | |||||
| Rubijervine | 253295 | Click to see | 413.60 | unknown |
https://doi.org/10.1007/BF01167577 https://doi.org/10.1007/BF00580930 https://doi.org/10.1007/BF00567974 https://doi.org/10.1002/ARDP.19552881005 https://doi.org/10.1002/ARDP.19372750803 |
| Solanid-5-en-3beta,12alpha-diol | 591288 | Click to see | 413.60 | unknown |
https://doi.org/10.1002/ARDP.19372750803 https://doi.org/10.1002/ARDP.19552881005 |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal glycosides | |||||
| 2-[[10,17-dimethyl-17-[1-(5-methylpiperidin-2-yl)ethyl]-2,3,4,7,8,9,11,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol | 163006471 | Click to see | 559.80 | unknown | https://doi.org/10.1007/BF00566824 |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal glycosides / Steroidal saponins | |||||
| 11-Oxo-17,23-epoxyveratraman-3-yl hexopyranoside | 3605588 | Click to see | 587.70 | unknown |
https://doi.org/10.1016/0031-9422(96)00211-7 https://doi.org/10.1002/ARDP.19372750803 https://doi.org/10.1039/CT8793500405 https://doi.org/10.1002/ARDP.18902280906 |
| Pseudojervine | 16398499 | Click to see CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5C(=O)C4=C3C)C)OC7C(C(C(C(O7)CO)O)O)O)C)NC1 | 587.70 | unknown |
https://doi.org/10.1007/BF00580930 https://doi.org/10.1002/ARDP.18902280906 https://doi.org/10.1016/0031-9422(96)00211-7 https://doi.org/10.1039/CT8793500405 https://doi.org/10.1002/ARDP.19372750803 |
| > Organoheterocyclic compounds / Piperidines | |||||
| (3S,4aS,5S,6aS,6bS,9R,11aS,11bS)-3,5,9-trihydroxy-9-[(1R)-1-[(2S,3R,5S)-3-hydroxy-5-methylpiperidin-2-yl]ethyl]-10,11b-dimethyl-1,2,3,4,4a,5,6,6a,6b,7,8,11a-dodecahydrobenzo[a]fluoren-11-one | 163084703 | Click to see CC1CC(C(NC1)C(C)C2(CCC3C4CC(C5CC(CCC5(C4C(=O)C3=C2C)C)O)O)O)O | 461.60 | unknown | https://doi.org/10.1016/0031-9422(96)00211-7 |
| (3S,5S,6aS,6bS,9R,11aS,11bS)-3,5,9-trihydroxy-9-[(1R)-1-[(2S,3R,5S)-3-hydroxy-5-methylpiperidin-2-yl]ethyl]-10,11b-dimethyl-1,2,3,4,4a,5,6,6a,6b,7,8,11a-dodecahydrobenzo[a]fluoren-11-one | 102247144 | Click to see | 461.60 | unknown | https://doi.org/10.1016/0031-9422(96)00211-7 |
| 3,5,9-Trihydroxy-9-[1-(3-hydroxy-5-methylpiperidin-2-yl)ethyl]-10,11b-dimethyl-1,2,3,4,4a,5,6,6a,6b,7,8,11a-dodecahydrobenzo[a]fluoren-11-one | 163084702 | Click to see | 461.60 | unknown | https://doi.org/10.1016/0031-9422(96)00211-7 |
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