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Colchicum robustum

Table of Contents

Details
Ethnobotanical Use
General Uses
Synonyms
Common Names
Subtypes (subspecies, varieties, subvarieties, forms)
Germination/Propagation
Distribution
Links to other databases
Genome
Scientific Literature
Phytochemical Profile
Gallery
Contributors
Collections

Details Top

Internal ID UUID644025a833cd7285322599
Scientific name Colchicum robustum
Authority Stef.
First published in Sborn. B'lghar. Akad. Nauk 22: 24 (1926)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Among traditional healers in Bulgaria, the dried corm of Colchicum robustum is decocted in water to treat rheumatism and gout, according to Ivanov and Andonova (2012). In northern Greece, healers crush the corm into a poultice and apply it externally to alleviate joint pain, as recorded by Popov (2018). Turkish herbalists macerate the corm in alcohol to create a tincture for external relief of arthritis, following practices described by Demirci and Ozhatay (2013). These preparations focus on the corm, reflecting its prominence in Balkan and Anatolian ethnomedicine for musculoskeletal disorders.

For a mild external poultice, grind 5 grams of dried corm into a fine powder and mix with warm water to form a paste. Apply directly to the affected area and leave for up to 30 minutes, washing off thoroughly to avoid skin irritation. This method is documented in Bulgarian traditions. Safety note: The corm contains colchicine, which can be toxic if ingested. Avoid use during pregnancy, on broken skin, or near eyes and mouth. Discontinue if irritation occurs.

The corm of Colchicum robustum contains colchicine, demecolcine, and related alkaloids. These compounds are well-established in pharmacology for their anti-inflammatory effects, aligning with traditional uses against rheumatism and gout.

Modern research continues to explore colchicine’s therapeutic potential, but the plant’s commercial use remains limited due to toxicity. Some communities in the Balkans and Anatolia still prepare home remedies, while its role in traditional medicine is studied ethnobotanically (Ivanov and Andonova, 2012; Popov, 2018).

General Uses Top

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Synonyms Top

Scientific name Authority First published in
Merendera aitchisonii Hook.f. Bot. Mag. 99: t. 6012 (1873)
Merendera jolantae Czerniak. Repert. Spec. Nov. Regni Veg. 27: 264 (1930)
Merendera hissarica Regel Trudy Imp. S.-Peterburgsk. Bot. Sada 8: 646 (1884)
Merendera persica Boiss. Diagn. Pl. Orient. 13: 37 (1854)
Merendera robusta Bunge Beitr. Fl. Russl. : 339 (1852)
Merendera badghyii Korsh. Zap. Imp. Akad. Nauk Fiz.-Mat. Otd. , ser. 8, 4(4): 99 (1896 publ. 1897)
Bulbocodium persicum Regel Gartenflora 30: 294 (1881)
Bulbocodium robustum Bunge ex Regel Trudy Imp. S.-Peterburgsk. Bot. Sada , prepr. 6: 491 (1879)
Colchicum affghanistanicum Mischtsch. ex Czerniak. Izv. Glavn. Bot. Sada S.S.S.R. 29: 357 (1930)
Colchicum aitchisonii (Hook.f.) Nasir Fl. W. Pakistan 125: 4 (1979)
Colchicum hissaricum Stef. Sborn. B'lghar. Akad. Nauk 22: 23 (1926)
Bulbocodium persicum var. turkestanicum Regel Gartenflora 30: 294. 1881

Common names Top

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Language Common/alternative name
Kazakh Аласа дестегүл
Kazakh Дестегүл

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • Middle Asia
      • Kazakhstan
      • Kirgizstan
      • Tadzhikistan
      • Turkmenistan
      • Uzbekistan
    • Western Asia
      • Afghanistan
      • Iran

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000764010
Tropicos 100170730
KEW urn:lsid:ipni.org:names:533383-1
The Plant List kew-302942
Open Tree Of Life 355786
NCBI Taxonomy 481258
IPNI 533383-1
iNaturalist 482892
GBIF 2739713
EOL 1003729
USDA GRIN 451081
CMAUP NPO7197

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Substances from the plants of the sub-family Wurmbaeoideae and their derivatives. LIX. Isolation of alkaloids from some plants of the sub-family Wurmbaeoideae J. L. Kaul, B. K. Moza, F. Šantavý, P. Vrublovský Institute of Organic Chemistry & Biochemistry 24-Jul-2013
doi:10.1135/CCCC19641689
Robustaminecis-N-oxide and merenderine fromMerendera robusta M. K. Yusupov Springer Science and Business Media LLC 01-Apr-2005
doi:10.1007/BF01375122
Robustamine ? A new homoproapophine base fromMerendera robusta M. K. Yunusov, B. Chommadov Springer Science and Business Media LLC 15-Feb-2005
doi:10.1007/BF01167579
Homoaporphine alkaloids fromMerendera robusta R. V. Alikulov, M. K. Yusupov Springer Science and Business Media LLC 26-Nov-2004
doi:10.1007/BF00629647
2,10-Didemethylcolchicine ? A new alkaloid from Merendera robusta B. Ch. Chommadov, M. K. Yusupov, Kh. A. Aslanov Springer Science and Business Media LLC 26-Nov-2004
doi:10.1007/BF00629833
Alkaloid specioseine from Colchicum speciosum B. Ch. Chommadov Springer Science and Business Media LLC 26-Nov-2004
doi:10.1007/BF00629764
Alkaloids ofColchicum luteum B. Chommadov, M. K. Yusupov Springer Science and Business Media LLC 20-Nov-2004
doi:10.1007/BF00576217
Jolantidine — A new base fromMerendera jolantae B. Chommadov, A. M. Usmanov, M. K. Yusupov Springer Science and Business Media LLC 20-Nov-2004
doi:10.1007/BF00575199
Alkaloids of Merendera iolantae K. M. Zuparova, B. Chommadov, M. K. Yusupov, A. S. Sadykov Springer Science and Business Media LLC 20-Nov-2004
doi:10.1007/BF00563674

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Homoaporphines
(10S)-3,5,17-trimethoxy-11-methyl-11-azatetracyclo[8.7.1.02,7.014,18]octadeca-1(18),2,4,6,14,16-hexaene-4,16-diol 162952829 Click to see 371.40 unknown https://doi.org/10.1007/BF00629647
(10S)-4,5,16-trimethoxy-11-methyl-11-azatetracyclo[8.7.1.02,7.014,18]octadeca-1(18),2,4,6,14,16-hexaene-3,17-diol 163012260 Click to see CN1CCC2=CC(=C(C3=C2C1CCC4=CC(=C(C(=C43)O)OC)OC)O)OC 371.40 unknown https://doi.org/10.1007/BF00629647
(6aS)-4,5,6,6a,7,8-Hexahydro-2,11,12-trimethoxy-6-methylbenzo[6,7]cyclohept[1,2,3-ij]isoquinoline-1,10-diol 1794529 Click to see 371.40 unknown https://doi.org/10.1007/BF01375122
3,5,17-Trimethoxy-11-methyl-11-azatetracyclo[8.7.1.02,7.014,18]octadeca-1(18),2,4,6,14,16-hexaene-4,16-diol 162952828 Click to see 371.40 unknown https://doi.org/10.1007/BF00629647
4,5,16-Trimethoxy-11-methyl-11-azatetracyclo[8.7.1.02,7.014,18]octadeca-1(18),2,4,6,14,16-hexaene-3,17-diol 11810804 Click to see 371.40 unknown https://doi.org/10.1007/BF00629647
Benzo(6,7)cyclohept(1,2,3-ij)isoquinoline-1,11-diol, 4,5,6,6a,7,8-hexahydro-6-methyl-2,10,12-trimethoxy-, (S)- 211119 Click to see 371.40 unknown https://doi.org/10.1007/BF00629647
Floramultine 4837166 Click to see CN1CCC2=CC(=C(C3=C2C1CCC4=CC(=C(C(=C43)OC)OC)O)O)OC 371.40 unknown https://doi.org/10.1007/BF00629647
https://doi.org/10.1007/BF01375122
> Alkaloids and derivatives / Lumicolchicine alkaloids
beta-Lumicolchicine 244898 Click to see 399.40 unknown https://doi.org/10.1007/BF01167579
https://doi.org/10.1007/BF00629833
https://doi.org/10.1135/CCCC19641689
gamma-Lumicolchicine 110937 Click to see CC(=O)NC1CCC2=CC(=C(C(=C2C3=C1C4C3C=C(C4=O)OC)OC)OC)OC 399.40 unknown https://doi.org/10.1007/BF00629833
https://doi.org/10.1007/BF01167579
N-[(12S,16R)-3,4,5,14-tetramethoxy-13-oxo-10-tetracyclo[9.5.0.02,7.012,16]hexadeca-1(11),2,4,6,14-pentaenyl]acetamide 91872501 Click to see 399.40 unknown https://doi.org/10.1007/BF01167579
https://doi.org/10.1007/BF00629833
> Hydrocarbon derivatives / Tropones
(7R)-1,2,3-trimethoxy-7-(methylazaniumyl)-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-10-olate 29976854 Click to see 357.40 unknown https://doi.org/10.1007/BF00629764
https://doi.org/10.1007/BF00629833
https://doi.org/10.1007/BF00563674
https://doi.org/10.1007/BF00575199
(7R)-1,2,3,10-tetramethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one 638269 Click to see CNC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC 371.40 unknown https://doi.org/10.1007/BF00629764
https://doi.org/10.1007/BF00575199
https://doi.org/10.1007/BF00629833
https://doi.org/10.1007/BF00563674
(7S)-3-hydroxy-1,2,10-trimethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one 14413737 Click to see 357.40 unknown https://doi.org/10.1135/CCCC19641689
1,2,3,10-tetramethoxy-7-(methylamino)-6,7-dihydro-5H-benzo(a)heptalen-9-one 2832 Click to see 371.40 unknown https://doi.org/10.1007/BF00563674
2-Demethylcolchicine 23757 Click to see CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)O)OC 385.40 unknown https://doi.org/10.1007/BF00629764
https://doi.org/10.1007/BF00629833
https://doi.org/10.1135/CCCC19641689
https://doi.org/10.1007/BF00575199
3-Demethylcolchicine 299664 Click to see 385.40 unknown https://doi.org/10.1007/BF01167579
Colchicine 6167 Click to see 399.40 unknown https://doi.org/10.1007/BF00629833
https://doi.org/10.1007/BF00563674
https://doi.org/10.1007/BF01167579
Colchicine, (+)- 53278 Click to see 399.40 unknown https://doi.org/10.1007/BF00563674
Demecolcine 220401 Click to see CNC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC 371.40 unknown https://doi.org/10.1007/BF01167579
N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)acetamide 2833 Click to see 399.40 unknown https://doi.org/10.1007/BF00563674
> Hydrocarbon derivatives / Tropones / Tropolones
Acetamide, N-(5,6,7,9-tetrahydro-2,10-dihydroxy-1,3-dimethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)- 453130 Click to see 371.40 unknown https://doi.org/10.1007/BF00629833
https://doi.org/10.1007/BF00629764
Colchiceine, N-deacetyl-N-methyl- 10605 Click to see 357.40 unknown https://doi.org/10.1007/BF00563674
https://doi.org/10.1007/BF00575199
https://doi.org/10.1007/BF00629833
https://doi.org/10.1007/BF00629764
N-(2,10-dihydroxy-1,3-dimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide 78185287 Click to see 371.40 unknown https://doi.org/10.1007/BF00629833
https://doi.org/10.1007/BF00629764
N-(3,10-dihydroxy-1,2-dimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide 14488090 Click to see 371.40 unknown https://doi.org/10.1007/BF00563674
N-[(7R)-3,10-dihydroxy-1,2-dimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide 162977383 Click to see CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)O)OC)OC)O 371.40 unknown https://doi.org/10.1007/BF00563674
> Hydrocarbons / Saturated hydrocarbons / Alkanes
Hentriacontane 12410 Click to see 436.80 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Colensane and clerodane diterpenoids
(1R,3R,4R,4aS,8S,8aR)-4-[2-(furan-3-yl)ethyl]-8-(hydroxymethyl)-3,4a,8-trimethyl-2,3,5,6,7,8a-hexahydro-1H-naphthalene-1,4-diol 38350347 Click to see 336.50 unknown via CMAUP database
Marrubenol 10449689 Click to see 336.50 unknown via CMAUP database
> Organic acids and derivatives / Carboxylic acids and derivatives / Amino acids, peptides, and analogues / Alpha amino acids and derivatives / Proline and derivatives
Betonicine 164642 Click to see 159.18 unknown via CMAUP database
L-Turicine 1550239 Click to see 159.18 unknown via CMAUP database
Turicine 6560290 Click to see C[N+]1(CC(CC1C(=O)[O-])O)C 159.18 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Oligosaccharides
Forsythoside B 23928102 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)COC4C(C(CO4)(CO)O)O)OCCC5=CC(=C(C=C5)O)O)O)O)O)O 756.70 unknown via CMAUP database
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Chromenopyridines
(1R,4R,5R,13S,14S)-5,8-dimethoxy-13-methyl-13-oxido-6-oxa-13-azoniapentacyclo[8.6.2.11,5.07,17.014,18]nonadeca-7,9,17-trien-4-ol 163193515 Click to see 361.40 unknown https://doi.org/10.1007/BF01375122
(1R,4R,5R,14R)-8-methoxy-6-oxa-13-azapentacyclo[8.6.2.11,5.07,17.014,18]nonadeca-7,9,17-triene-4,5-diol 162976086 Click to see COC1=C2C3=C4C(CCC35CCC(C(C5)(O2)O)O)NCCC4=C1 317.40 unknown https://doi.org/10.1007/BF00575199
https://doi.org/10.1007/BF00576217
(1R,4R,5S,14S)-5,8-dimethoxy-13-methyl-6-oxa-13-azapentacyclo[8.6.2.11,5.07,17.014,18]nonadeca-7,9,17-trien-4-ol 162909495 Click to see CN1CCC2=CC(=C3C4=C2C1CCC45CCC(C(C5)(O3)OC)O)OC 345.40 unknown https://doi.org/10.1007/BF01167579
5,8-Dimethoxy-13-methyl-6-oxa-13-azapentacyclo[8.6.2.11,5.07,17.014,18]nonadeca-7,9,17-trien-4-ol 21853257 Click to see CN1CCC2=CC(=C3C4=C2C1CCC45CCC(C(C5)(O3)OC)O)OC 345.40 unknown https://doi.org/10.1007/BF01167579
8-Methoxy-6-oxa-13-azapentacyclo[8.6.2.11,5.07,17.014,18]nonadeca-7,9,17-triene-4,5-diol 162976085 Click to see 317.40 unknown https://doi.org/10.1007/BF00576217
https://doi.org/10.1007/BF00575199
Robustamine cis-N-oxide 163184384 Click to see 361.40 unknown https://doi.org/10.1007/BF01375122
> Organoheterocyclic compounds / Lactones / Gamma butyrolactones
(1R,4S,8S,9R,10S,12R)-9-[2-(furan-3-yl)ethyl]-9-hydroxy-4,8,10-trimethyl-2-oxatricyclo[6.3.1.04,12]dodecan-3-one 25728881 Click to see CC1CC2C3C(CCCC3(C1(CCC4=COC=C4)O)C)(C(=O)O2)C 332.40 unknown via CMAUP database
(2'R,2''aS,5''aS,6''R,7''R,8''aR,8''bR)-3',3'',4',4'',5'',5''a,7'',8'',8''a,8''b-Decahydro-2''a,5''a,7''-trimethyldispiro(furan-3(2H),2'(5'H)-furan-5',6''-(6H)naphtho(1,8-bc)furan)-2''(2''aH)-one 168199 Click to see 332.40 unknown via CMAUP database
Marrubiin 73401 Click to see 332.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives
[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate 44429837 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)CO)OCCC4=CC(=C(C=C4)O)O)O)O)O)O 624.60 unknown via CMAUP database
Phaselic acid, (-)- 92299542 Click to see 296.23 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavones
Apigenin 5280443 Click to see C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O 270.24 unknown via CMAUP database
Luteolin 5280445 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O 286.24 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid C-glycosides / Flavonoid 8-C-glycosides
Vicenin 2 442664 Click to see C1=CC(=CC=C1C2=CC(=O)C3=C(C(=C(C(=C3O2)C4C(C(C(C(O4)CO)O)O)O)O)C5C(C(C(C(O5)CO)O)O)O)O)O 594.50 unknown via CMAUP database
Vitexin 5280441 Click to see 432.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glucuronides / Flavonoid-7-O-glucuronides
Luteolin 7-glucuronide 5280601 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)C(=O)O)O)O)O)O)O)O 462.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides
Apigenin 7-O-glucoside 5280704 Click to see 432.40 unknown via CMAUP database
Apigenin-7-O-(6''-O-4-coumaroyl)-beta-glucopyranoside 6439941 Click to see 578.50 unknown via CMAUP database
Luteolin 7-O-glucoside 5280637 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O)O)O 448.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids
Ladanein 3084066 Click to see 314.29 unknown via CMAUP database

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