Harpagophytum zeyheri - Unknown
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Internal ID UUID64401fbe49365550383675
Scientific name Harpagophytum zeyheri
Authority Decne.
First published in Ann. Sci. Nat., Bot. , sér. 5, 3: 329 (1865)

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Synonyms Top

Scientific name Authority First published in
Uncaria zeyheri Kuntze Revis. Gen. Pl. 2: 481. 1891 [5 Nov 1891]

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Africa
    • South Tropical Africa
      • Angola
      • Mozambique
      • Zambia
      • Zimbabwe
    • Southern Africa
      • Botswana
      • Caprivi Strip
      • Namibia
      • Northern Provinces

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000715794
Tropicos 24300043
KEW urn:lsid:ipni.org:names:675825-1
Open Tree Of Life 5522119
Observations.org 904925
NCBI Taxonomy 1503107
IPNI 675825-1
iNaturalist 338770
iNaturalist 338768
iNaturalist 338767
iNaturalist 338769
GBIF 3585330
Elurikkus 378567
USDA GRIN 423428

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Recent trends of machine learning applied to multi-source data of medicinal plants Zhang Y, Wang Y J Pharm Anal 25-Jul-2023
PMCID:PMC10785154
doi:10.1016/j.jpha.2023.07.012
PMID:38223450
Sources, Transformations, Syntheses, and Bioactivities of Monoterpene Pyridine Alkaloids and Cyclopenta[c]pyridine Derivatives Zhang X, Tao F, Cui T, Luo C, Zhou Z, Huang Y, Tan L, Peng W, Wu C Molecules 24-Oct-2022
PMCID:PMC9656638
doi:10.3390/molecules27217187
PMID:36364013
Treatment of Gastrointestinal Disorders—Plants and Potential Mechanisms of Action of Their Constituents Czigle S, Bittner Fialová S, Tóth J, Mučaji P, Nagy M Molecules 30-Apr-2022
PMCID:PMC9105531
doi:10.3390/molecules27092881
PMID:35566230
Operational definition of complementary, alternative, and integrative medicine derived from a systematic search Ng JY, Dhawan T, Dogadova E, Taghi-Zada Z, Vacca A, Wieland LS, Moher D BMC Complement Med Ther 12-Apr-2022
PMCID:PMC9006507
doi:10.1186/s12906-022-03556-7
PMID:35413882
DNA Barcode Authentication of Devil’s Claw Herbal Dietary Supplements Diaz-Silveira GL, Deutsch J, Little DP Plants (Basel) 24-Sep-2021
PMCID:PMC8540935
doi:10.3390/plants10102005
PMID:34685813
In vitro antioxidant activity of crude extracts of Harpagophytum zeyheri and their anti-inflammatory and cytotoxicity activity compared with diclofenac Ncube SF, McGaw LJ, Njoya EM, Ndagurwa HG, Mundy PJ, Sibanda S BMC Complement Med Ther 23-Sep-2021
PMCID:PMC8461911
doi:10.1186/s12906-021-03407-x
PMID:34556115
From Bush Medicine to Modern Phytopharmaceutical: A Bibliographic Review of Devil’s Claw (Harpagophytum spp.) Brendler T Pharmaceuticals (Basel) 27-Jul-2021
PMCID:PMC8398729
doi:10.3390/ph14080726
PMID:34451822
Analysis of Effectiveness of a Supplement Combining Harpagophytum procumbens, Zingiber officinale and Bixa orellana in Healthy Recreational Runners with Self-Reported Knee Pain: A Pilot, Randomized, Triple-Blind, Placebo-Controlled Trial González-Gross M, Quesada-González C, Rueda J, Sillero-Quintana M, Issaly N, Díaz AE, Gesteiro E, Escobar-Toledo D, Torres-Peralta R, Roller M, Guadalupe-Grau A Int J Environ Res Public Health 22-May-2021
PMCID:PMC8196851
doi:10.3390/ijerph18115538
PMID:34067240
Pharmacokinetics of harpagoside in horses after intragastric administration of a Devil's claw (Harpagophytum procumbens) extract Axmann S, Hummel K, Nöbauer K, Razzazi‐Fazeli E, Zitterl‐Eglseer K J Vet Pharmacol Ther 22-Sep-2018
PMCID:PMC7379497
doi:10.1111/jvp.12716
PMID:30242850
DNA Barcoding of Online Herbal Supplements: Crowd-sourcing Pharmacovigilance in High School Molina J, Sherpa C, Ng J, Sonam T, Stuhr N Open Life Sci 06-Apr-2018
PMCID:PMC7874675
doi:10.1515/biol-2018-0007
PMID:33817067
Ethno-Veterinary Practices Amongst Livestock Farmers in Ngamiland District, Botswana Gabalebatse M, Ngwenya BN, Teketay D, Kolawole OD Afr J Tradit Complement Altern Med 12-Apr-2013
PMCID:PMC3777591
doi:10.4314/ajtcam.v10i3.16
PMID:24146479
Ethnobotanical study of indigenous knowledge on medicinal plant use by traditional healers in Oshikoto region, Namibia Cheikhyoussef A, Shapi M, Matengu K, Mu Ashekele H J Ethnobiol Ethnomed 09-Mar-2011
PMCID:PMC3062575
doi:10.1186/1746-4269-7-10
PMID:21388534
New and known iridoid- and phenylethanoid glycosides from Harpagophytum procumbens and their in vitro inhibition of human leukocyte elastase. Boje K, Lechtenberg M, Nahrstedt A Planta Med 01-Sep-2003
doi:10.1055/S-2003-43225
PMID:14598207
Two new pyridine monoterpene alkaloids by chemical conversion of a commercial extract of harpagophytum procumbens. Baghdikian B, Ollivier E, Faure R, Debrauwer L, Rathelot P, Balansard G J Nat Prod 01-Feb-1999
doi:10.1021/NP980149C
PMID:10075743
An analytical study, anti-inflammatory and analgesic effects of Harpagophytum procumbens and Harpagophytum zeyheri. Baghdikian B, Lanhers MC, Fleurentin J, Ollivier E, Maillard C, Balansard G, Mortier F Planta Med 01-Apr-1997
doi:10.1055/S-2006-957638
PMID:9140234

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Iridoid O-glycosides
(1S,4aS,5S,7S,7aR)-1,4a,5,6,7,7a-Hexahydro-4a,5,7-trihydroxy-7-methylcyclopenta[c]pyran-1-yl beta-D-glucopyranoside 145706031 Click to see CC1(CC(C2(C1C(OC=C2)OC3C(C(C(C(O3)CO)O)O)O)O)O)O 364.34 unknown https://doi.org/10.1021/NP980149C
[(1S,4aS,5R,7S,7aS)-4a,5-dihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate 101402541 Click to see CC1(CC(C2(C1C(OC=C2)OC3C(C(C(C(O3)CO)O)O)O)O)O)OC(=O)C=CC4=CC(=C(C=C4)O)OC 540.50 unknown https://doi.org/10.1055/S-2003-43225
8-Cinnamoylmyoporoside 101402540 Click to see CC1(CC(C2C1C(OC=C2)OC3C(C(C(C(O3)CO)O)O)O)O)OC(=O)C=CC4=CC=CC=C4 478.50 unknown https://doi.org/10.1055/S-2003-43225
Harpagide 93045 Click to see CC1(CC(C2(C1C(OC=C2)OC3C(C(C(C(O3)CO)O)O)O)O)O)O 364.34 unknown https://doi.org/10.1021/NP980149C
Harpagoside 5281542 Click to see CC1(CC(C2(C1C(OC=C2)OC3C(C(C(C(O3)CO)O)O)O)O)O)OC(=O)C=CC4=CC=CC=C4 494.50 unknown https://doi.org/10.1055/S-2003-43225
https://doi.org/10.1021/NP980149C
https://doi.org/10.1055/S-2006-957638
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Aryl ketones
(6E)-6-[[5-(hydroxymethyl)furan-2-yl]methylidene]-7-methyl-7H-cyclopenta[c]pyridin-5-one 10706174 Click to see CC1C2=C(C=CN=C2)C(=O)C1=CC3=CC=C(O3)CO 255.27 unknown https://doi.org/10.1021/NP980149C
(6E)-7-methyl-6-[(5-methylfuran-2-yl)methylidene]-7H-cyclopenta[c]pyridin-5-one 10823898 Click to see CC1C2=C(C=CN=C2)C(=O)C1=CC3=CC=C(O3)C 239.27 unknown https://doi.org/10.1021/NP980149C
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Aryl ketones / Aryl alkyl ketones
7-Methyl-6,7-dihydrocyclopenta[c]pyridin-5-one 11252092 Click to see CC1CC(=O)C2=C1C=NC=C2 147.17 unknown https://doi.org/10.1021/NP980149C
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Cinnamic acids
2-Propenoic acid, 3-phenyl- 8784 Click to see C1=CC=C(C=C1)C=CC(=O)O 148.16 unknown https://doi.org/10.1055/S-2003-43225
Cinnamic acid 444539 Click to see C1=CC=C(C=C1)C=CC(=O)O 148.16 unknown https://doi.org/10.1055/S-2003-43225
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives
{6-[2-(3,4-Dihydroxyphenyl)ethoxy]-3,5-dihydroxy-4-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]oxan-2-yl}methyl 3-(3,4-dihydroxyphenyl)prop-2-enoate 73323377 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2O)OCCC3=CC(=C(C=C3)O)O)COC(=O)C=CC4=CC(=C(C=C4)O)O)O)O)O)O 624.60 unknown https://doi.org/10.1055/S-2003-43225
2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-Deoxy-alpha-L-mannopyranosyl)-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-beta-D-glucopyranoside 132274946 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)CO)OCCC4=CC(=C(C=C4)O)O)O)O)O)O 624.60 unknown https://doi.org/10.1055/S-2003-43225
Verbascoside 5281800 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)CO)OCCC4=CC(=C(C=C4)O)O)O)O)O)O 624.60 unknown https://doi.org/10.1055/S-2003-43225
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Hydroxycinnamic acid esters / Coumaric acid esters
Pagoside 45783209 Click to see CC1=C(C(=CCOC2C(C(C(C(O2)CO)O)O)O)C(C1)OC(=O)C=CC3=CC=C(C=C3)O)C(=O)O 492.50 unknown https://doi.org/10.1055/S-2003-43225
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Hydroxycinnamic acids
Caffeic Acid 689043 Click to see C1=CC(=C(C=C1C=CC(=O)O)O)O 180.16 unknown https://doi.org/10.1055/S-2003-43225

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