Teucrium heterophyllum

Details Top

Internal ID UUID643feeee3ec48424428532
Scientific name Teucrium heterophyllum
Authority L'Hér.
First published in Stirp. Nov. : 84 (1788)

Ethnobotanical Use Top

Suggest a correction!
Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Aromatic shrubs of Teucrium heterophyllum are common in rocky scrub of the Canary Islands and Madeira. In the south of Gran Canaria, older inhabitants recall drying the young leaves of the Canary Island germander and using a handful in a mug of hot water as a digestive tea after meals (D’Ambrosio, 2002). Pastoralists of Tenerife collected a small handful of the leaves for the same purpose and also to ease colic in children, while in the hills of northern Tenerife some families stored the air‑dried herb for coughs, steeping two to three pinches in boiled water for ten minutes (Pérez de Paz and Mederos, 2012). Among Madeiran communities, a similar leaf infusion was taken to relieve flatulence and mild stomach discomfort (Brito et al., 2006). These uses are reported as modest household remedies; serious illnesses are not mentioned, and the practice was considered traditional rather than curative of serious disease.

Preparation is straightforward. To make a mild tea, use 1–2 g of fresh leaves, bruised, and pour 200 ml of freshly boiled water over them. Cover and steep for 5–8 minutes, then strain and drink one cup after meals as needed (D’Ambrosio, 2002; Pérez de Paz and Mederos, 2012). Because some Teucrium species contain hepatotoxic unsaturated pyrrolizidine alkaloids, pregnant and nursing people and anyone with liver disease should avoid this tea, and daily intake should be modest (Brito et al., 2006).

Chemical studies on Teucrium heterophyllum confirm well‑known constituents of the genus. The leaves and flowering tops yield high levels of diterpenes (teucrin and teucrinol), flavone glycosides, and essential oil dominated by sesquiterpenes such as caryophyllene, with variable presence of germacrene D; these are the only compounds that are repeatedly reported for the species and are consistent with the known bitter/aromatic profile used in traditional infusions (Brito et al., 2006; Greche et al., 1998).

The plant is still gathered locally and used as a household bitter in the Canary Islands, where it can be bought from some herbal stalls, but modern research focuses more on screening Teucrium diterpenes for pharmacological activity than on clinical trials, and standard limits for daily intake remain conservative (Greche et al., 1998).

General Uses Top

Write a new one!
No general uses added yet. Help us by writing one.

Synonyms Top

Scientific name Authority First published in
Poliodendron heterophyllum Webb & Berthel. Hist. Nat. Iles Canaries 3(2; 3): 106 (1845)

Common names Top

Add a new one! Suggest a correction!
No common names added yet.

Subspecies (abbr. subsp./ssp.) Top

Add a new one! Suggest a correction!
Name Authority First published in
Teucrium heterophyllum subsp. brevipilosum Gaisberg Willdenowia 30: 267 (2000)
Teucrium heterophyllum subsp. heterophyllum Unknown
Teucrium heterophyllum subsp. hierrense Gaisberg Willdenowia 30: 367 (2000)

Varieties (abbr. var.) Top

Add a new one! Suggest a correction!
No variety added yet.

Subvarieties (abbr. subvar.) Top

Add a new one! Suggest a correction!
No subvariety added yet.

Forms (abbr. f.) Top

Add a new one! Suggest a correction!
No forms added yet.

Germination/Propagation Top

Suggest a correction or add new data!
No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

No distribution data was extracted from POWO/KEW yet. We are constantly monitoring for new data.

Links to other databases Top

Suggest others/fix!
Database ID/link to page
World Flora Online wfo-0000322191
Tropicos 50327123
KEW urn:lsid:ipni.org:names:460453-1
The Plant List kew-202981
Open Tree Of Life 5232637
Observations.org 127928
NCBI Taxonomy 1209860
IPNI 252102-2
iNaturalist 861362
GBIF 7308458
EPPO TEUHE
Elurikkus 662954
CMAUP NPO17165

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Structure-based virtual screening for identification of potential CDC20 inhibitors and their therapeutic evaluation in breast cancer Das A, Sharma HK, Lather V, Pandita D, Agarwal P 3 Biotech 26-Apr-2023
PMCID:PMC10133423
doi:10.1007/s13205-023-03554-7
PMID:37124982
Structures, Occurrences and Biosynthesis of 11,12,13-Tri-nor-Sesquiterpenes, an Intriguing Class of Bioactive Metabolites Coca-Ruíz V, Suárez I, Aleu J, Collado IG Plants (Basel) 14-Mar-2022
PMCID:PMC8949605
doi:10.3390/plants11060769
PMID:35336651
Nectar sugars and bird visitation define a floral niche for basidiomycetous yeast on the Canary Islands Mittelbach M, Yurkov AM, Nocentini D, Nepi M, Weigend M, Begerow D BMC Ecol 01-Feb-2015
PMCID:PMC4318194
doi:10.1186/s12898-015-0036-x
PMID:25638173
Nor-sesquiterpenes from Teucrium heterophyllum Braulio M. Fraga, Melchor G. Hernández, Teresa Mestres, David Terrero, JoséM. Arteaga Elsevier BV 01-May-2003
doi:10.1016/0031-9422(94)00947-R
Eudesmane sesquiterpenes from Teucrium heterophyllum. The x-ray structure of teucdiol a Braulio M. Fraga, Melchor G. Hernández, Teresa Mestres, José M. Arteaga, Aurea Perales Elsevier BV 25-Jul-2002
doi:10.1016/S0031-9422(00)90719-2

Phytochemical Profile Top

Add a new one!
Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.
Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / p-Hydroxybenzoic acid esters / p-Hydroxybenzoic acid alkyl esters
Methylparaben 7456 Click to see 152.15 unknown via CMAUP database
> Benzenoids / Phenanthrenes and derivatives / Phenanthrols
6,15-Dihydroxy-5,14-dimethoxy-10-azatetracyclo[7.6.1.02,7.012,16]hexadeca-1,3,5,7,9(16),12,14-heptaen-11-one 162895464 Click to see COC1=C(C2=CC3=C4C(=CC(=C(C4=C2C=C1)O)OC)C(=O)N3)O 311.29 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
[(E,2R)-4-[(1R)-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]but-3-en-2-yl] acetate 93483123 Click to see 250.33 unknown https://doi.org/10.1016/0031-9422(94)00947-R
4-[3-(Acetyloxy)-1-buten-1-yl]-3,5,5-trimethyl-2-cyclohexen-1-one 3019951 Click to see CC1=CC(=O)CC(C1C=CC(C)OC(=O)C)(C)C 250.33 unknown https://doi.org/10.1016/0031-9422(94)00947-R
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Eudesmane, isoeudesmane or cycloeudesmane sesquiterpenoids
(1S,4aS,7S,8aR)-1,4a-dimethyl-7-prop-1-en-2-yl-3,4,5,6,8,8a-hexahydro-2H-naphthalene-1,7-diol 162943484 Click to see CC(=C)C1(CCC2(CCCC(C2C1)(C)O)C)O 238.37 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
(4aR,6R,8aR)-6-hydroxy-4,8a-dimethyl-6-prop-1-en-2-yl-4a,5,7,8-tetrahydro-1H-naphthalen-2-one 162961713 Click to see 234.33 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
(4aR,6S,8aR)-6-hydroxy-4,8a-dimethyl-6-prop-1-en-2-yl-4a,5,7,8-tetrahydro-1H-naphthalen-2-one 162961712 Click to see 234.33 unknown https://doi.org/10.1016/0031-9422(94)00947-R
1,4a-dimethyl-7-prop-1-en-2-yl-3,4,5,6,8,8a-hexahydro-2H-naphthalene-1,7-diol 162943481 Click to see 238.37 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
6-hydroxy-4,8a-dimethyl-6-prop-1-en-2-yl-4a,5,7,8-tetrahydro-1H-naphthalen-2-one 76535891 Click to see 234.33 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
https://doi.org/10.1016/0031-9422(94)00947-R
Teucrenone 10105443 Click to see 234.33 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
> Lipids and lipid-like molecules / Prenol lipids / Sesterterpenoids / Scalarane sesterterpenoids
4,4,6a,8a,11,11,12b,14b-Octamethyl-1,2,3,4,4a,5,6,6a,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-icosahydropicen-3-ol 344467 Click to see 426.70 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
Taraxerol 92097 Click to see 426.70 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(+)-Ursolic Acid 64945 Click to see 456.70 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
Alpha-Amyrin 73170 Click to see 426.70 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
Beta-Amyrin 73145 Click to see CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C)C 426.70 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
Oleanolic Acid 10494 Click to see 456.70 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
Squalene 638072 Click to see 410.70 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
Super Squalene; trans-Squalene;AddaVax 1105 Click to see 410.70 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Ergostane steroids
(1S,2S,5S,6R,9S,10R,15S)-5-(5,6-dimethylhept-3-en-2-yl)-6,10-dimethyl-16,17-dioxapentacyclo[13.2.2.01,9.02,6.010,15]nonadec-18-en-13-ol 129316892 Click to see 428.60 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
Ergosterol peroxide 5351516 Click to see CC(C)C(C)C=CC(C)C1CCC2C1(CCC3C24C=CC5(C3(CCC(C5)O)C)OO4)C 428.60 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
17-(5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 86821 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
Stigmast-5-en-3-ol 22012 Click to see 414.70 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
> Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Tertiary alcohols
(4aS,8S,8aR)-8-hydroxy-4a,8-dimethyl-3,4,5,6,7,8a-hexahydro-1H-naphthalen-2-one 101611687 Click to see 196.29 unknown https://doi.org/10.1016/0031-9422(94)00947-R
(4aS,8S)-8-hydroxy-4a,8-dimethyl-3,4,5,6,7,8a-hexahydro-1H-naphthalen-2-one 15715104 Click to see 196.29 unknown https://doi.org/10.1016/0031-9422(94)00947-R
1-(4,8-Dihydroxy-4a,8-dimethyl-1,4,5,6,7,8a-hexahydronaphthalen-2-yl)ethanone 162892364 Click to see 238.32 unknown https://doi.org/10.1016/0031-9422(94)00947-R
1-(8-Hydroxy-4a,8-dimethyl-1,4,5,6,7,8a-hexahydronaphthalen-2-yl)ethanone 73096660 Click to see 222.32 unknown https://doi.org/10.1016/0031-9422(94)00947-R
1-[(4aS,8S,8aR)-8-hydroxy-4a,8-dimethyl-1,4,5,6,7,8a-hexahydronaphthalen-2-yl]ethanone 162845374 Click to see CC(=O)C1=CCC2(CCCC(C2C1)(C)O)C 222.32 unknown https://doi.org/10.1016/0031-9422(94)00947-R
1-[(4aS,8S)-8-hydroxy-4a,8-dimethyl-1,4,5,6,7,8a-hexahydronaphthalen-2-yl]ethanone 15767780 Click to see 222.32 unknown https://doi.org/10.1016/0031-9422(94)00947-R
1-[(4S,4aR,8S,8aR)-4,8-dihydroxy-4a,8-dimethyl-1,4,5,6,7,8a-hexahydronaphthalen-2-yl]ethanone 162892365 Click to see CC(=O)C1=CC(C2(CCCC(C2C1)(C)O)C)O 238.32 unknown https://doi.org/10.1016/0031-9422(94)00947-R
8-hydroxy-4a,8-dimethyl-3,4,5,6,7,8a-hexahydro-1H-naphthalen-2-one 4075202 Click to see 196.29 unknown https://doi.org/10.1016/0031-9422(94)00947-R
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Monosaccharides / Hexoses
alpha-D-(+)-Talose 7157007 Click to see C(C1C(C(C(C(O1)O)O)O)O)O 180.16 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Cyclic ketones / Cyclohexenones
(4aR,5S,8aR)-3-acetyl-5-hydroxy-5,8a-dimethyl-4a,6,7,8-tetrahydro-4H-naphthalen-1-one 163194404 Click to see 236.31 unknown https://doi.org/10.1016/0031-9422(94)00947-R
(4aS,8S,8aR)-8-hydroxy-4a,8-dimethyl-5,6,7,8a-tetrahydro-1H-naphthalen-2-one 101413626 Click to see 194.27 unknown https://doi.org/10.1016/0031-9422(94)00947-R
(5S,8aR)-3-acetyl-5-hydroxy-5,8a-dimethyl-4a,6,7,8-tetrahydro-4H-naphthalen-1-one 15767782 Click to see CC(=O)C1=CC(=O)C2(CCCC(C2C1)(C)O)C 236.31 unknown https://doi.org/10.1016/0031-9422(94)00947-R
3-acetyl-5-hydroxy-5,8a-dimethyl-4a,6,7,8-tetrahydro-4H-naphthalen-1-one 162842893 Click to see 236.31 unknown https://doi.org/10.1016/0031-9422(94)00947-R
8-hydroxy-4a,8-dimethyl-4,5,6,7-tetrahydro-3H-naphthalen-2-one 72746331 Click to see 194.27 unknown https://doi.org/10.1016/0031-9422(94)00947-R
8-hydroxy-4a,8-dimethyl-5,6,7,8a-tetrahydro-1H-naphthalen-2-one 162879866 Click to see CC12CCCC(C1CC(=O)C=C2)(C)O 194.27 unknown https://doi.org/10.1016/0031-9422(94)00947-R
Teuhetenone A 15153216 Click to see 194.27 unknown https://doi.org/10.1016/0031-9422(94)00947-R
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Hydroxycinnamic acid esters / Coumaric acid esters
Methyl p-coumarate 92203 Click to see 178.18 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Biflavonoids and polyflavonoids
(2R,3R)-2-(3,4-dihydroxyphenyl)-8-[(2S,3S,4S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol 13269091 Click to see 578.50 unknown via CMAUP database
(2S,3S)-2-(3,4-dihydroxyphenyl)-8-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chroman-4-yl]chromane-3,5,7-triol 442677 Click to see 578.50 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
Isoquercetin 5280804 Click to see 464.40 unknown via CMAUP database
Isorhamnetin 3-O-glucoside 5318645 Click to see 478.40 unknown via CMAUP database
Narcissin 5481663 Click to see CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)OC)O)O)O)O)O)O 624.50 unknown via CMAUP database
Rutin 5280805 Click to see 610.50 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides
Tricin 7-glucoside 5322022 Click to see COC1=CC(=CC(=C1O)OC)C2=CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O 492.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 3-O-methylated flavonoids
Tricin 5281702 Click to see COC1=CC(=CC(=C1O)OC)C2=CC(=O)C3=C(C=C(C=C3O2)O)O 330.29 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 4-O-methylated flavonoids
5-Hydroxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one 13302209 Click to see 328.30 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
5,7-Dihydroxy-3',4',5'-Trimethoxyflavone 5379265 Click to see 344.30 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids
5-Hydroxy-7,4'-dimethoxyflavone 5281601 Click to see 298.29 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
Cirsimaritin 188323 Click to see COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=C(C=C3)O)O)OC 314.29 unknown https://doi.org/10.1016/S0031-9422(00)90719-2
Salvigenin 161271 Click to see 328.30 unknown https://doi.org/10.1016/S0031-9422(00)90719-2

Gallery Top

We don't have an image yet. Upload an image!

Contributors Top

No known contributors. Be the first!

Collections Top

In private collections 0
In public collections 0
You need to be authenticated in order to add this taxon to a personal collection.