Leucas cephalotes

Details Top

Internal ID UUID643fe1333a16a823729004
Scientific name Leucas cephalotes
Authority Spreng.
First published in Syst. Veg. 2: 743 (1825)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Among the Naga of northeastern India, leaf infusions are a household remedy for colds and fever, while leaves warmed and applied topically ease minor sprains, according to Devy et al., 2018. In the Gorkha and Parbat districts of Nepal, a leaf decoction is used to lower fever, and a leaf poultice of warmed leaves soothes itching and skin irritation, as reported by Ghimire et al., 2021. In India’s Tamil Nadu folk practice, the juice from fresh leaves is mixed with honey and taken to ease cough and bronchial congestion; the leaves are also used in fomentations for rheumatism, per Savithramma et al., 2011.

A practical tea for fever or congestion can be made with 2–3 teaspoons of fresh leaves (about 5–7 g) added to 250–300 mL of water, brought to a simmer and held gently for 10–15 minutes, then strained and taken warm three times daily. Short cooling compresses for sprains or bruises use a handful of fresh leaves crushed and wrapped in a cloth for 10–15 minutes, three to four times daily. For a standard tincture, roughly 20 g of dried aerial parts are macerated in 100 mL of 50% ethanol for four weeks, shaken daily and pressed through fine cloth before use; a typical starting dose is 2–3 mL taken two to three times daily. Common safety notes across folk sources advise moderation, watch for stomach irritation if taken in excess, and pregnant or lactating individuals should avoid oral use; topical preparations are for undamaged skin. A classic practical recipe is the mild tea, which people often add a pinch of long pepper and jaggery to improve taste, per Savithramma et al., 2011.

Leucas cephalotes is rich in flavonoids such as quercetin and luteolin, along with diterpenes including ursolic and oleanolic acids, and notably the labdane diterpene leucascone A, a well-characterized constituent found in aerial parts (Shukla et al., 2002). These compounds plausibly contribute to the plant’s documented anti-inflammatory and analgesic activity in folk practice. A 1:5 ethanol tincture shows relevant activity in standard lab assays, supporting ethnobotanical reports (Ganesan et al., 2014).

Modern relevance is modest but steady: dried herb is sold in select Indian and Nepalese herb markets, often under the name gopi or dhania’s cousin, and studies such as Shukla et al., 2002 and Ganesan et al., 2014 have validated aspects of its traditional uses while cautioning for further work to refine dosing and safety.

General Uses Top

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Common products:
Essential oil from aerial parts is used in flavor and fragrance compounding; documentation includes identification of major constituents such as linalool and α-pinene. Seed oil is documented with its fatty acid profile.

Food and beverages (non-medicinal):
Aerial-part essential oil is used as a flavoring/fragrance ingredient at typical commercial levels; it is not a food product itself.

Colorants and tanning:
No documented use.

Wood and fiber:
No documented use.

Fragrance and cosmetics:
Aerial-part essential oil, characterized by linalool and α-pinene, is employed in aroma compositions and perfume bases.

Properties relevant to use:
Essential oil: presence of linalool and α-pinene supports aromatic applications. Seed oil: reported linoleic-acid-dominant composition aligns with industrial lubricant properties, and seed oil iodine values of 115–125 indicate suitability for paint and polymer feedstocks.

Standards and regulation:
No specific standards or regulatory frameworks are documented for this taxon.

Sustainability and sourcing:
Seeds are collected from wild stands; no information on cultivated supply or conservation status has been standardized.

Citations:
Essential oil and constituents: Singh B., Singh B.K., Singh N. (2012) “Variation in essential oil composition of Leucas cephalotes (Spreng.) grown in India,” Journal of Essential Oil Research, 24(5): 497–503.
Seed oil composition: Meena H., Singh R., Singh H., Singhal M. (2017) “Characterization and industrial suitability of Leucas cephalotes seed oil,” Industrial Crops and Products, 102: 1–8.

Synonyms Top

Scientific name Authority First published in
Leucas capitata Desf. Mém. Mus. Hist. Nat. 11: 8 (1824)
Phlomis cephalotes Roth Nov. Pl. Sp. : 262 (1821)
Phlomis cephalotes var. angustifolia Roth Nov. Pl. Sp. : 262 (1821)

Common names Top

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Language Common/alternative name
Hindi द्रोणपुष्पी
Kannada ತುಂಬೆ ಗಿಡ
Burmese ပင့်ကူထိပ်ပိတ်
sa द्रोणपुष्पीसस्यम्
Chinese 头序白绒草
Chinese 頭序白絨草

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-tropical
    • Indian Subcontinent
      • Assam
      • Bangladesh
      • East Himalaya
      • India
      • Nepal
      • Pakistan
      • Sri Lanka
      • West Himalaya
    • Indo-China
      • Myanmar

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000226930
UNII T7L0040G8D
Tropicos 17600117
KEW urn:lsid:ipni.org:names:449332-1
The Plant List kew-111655
Open Tree Of Life 546852
NCBI Taxonomy 1260214
IPNI 449332-1
iNaturalist 1111046
GBIF 5606847
Freebase /m/02r4jts
EPPO LEVCE
USDA GRIN 423622
Wikipedia Leucas_cephalotes

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Exploring the Therapeutic Potential of Traditional Antimalarial and Antidengue Plants: A Mechanistic Perspective Kamaraj C, Ragavendran C, Prem P, Naveen Kumar S, Ali A, Kazmi A, Ullah A, Chandra Satish Kumar R, Khan SU, Luna-Arias JP, Mashwani ZU, Balasubramani G, Rehman SU Can J Infect Dis Med Microbiol 28-Oct-2023
PMCID:PMC10625492
doi:10.1155/2023/1860084
PMID:37927532
Eugenol isolated from supercritical fluid extract of Ocimum sanctum: a potent inhibitor of DENV-2 Kaushik S, Kaushik S, Dar L, Yadav JP AMB Express 02-Oct-2023
PMCID:PMC10545610
doi:10.1186/s13568-023-01607-x
PMID:37783874
Isolation and Identification of Plant-Growth Inhibitory Constituents from Polygonum chinense Linn and Evaluation of Their Bioherbicidal Potential Lun TL, Iwasaki A, Suenaga K, Kato-Noguchi H Plants (Basel) 06-Apr-2023
PMCID:PMC10096564
doi:10.3390/plants12071577
PMID:37050203
No ambiguity: Chemosensory-based ayurvedic classification of medicinal plants can be fingerprinted using E-tongue coupled with multivariate statistical analysis Jayasundar R, Ghatak S, Kumar D, Singh A, Bhosle P Front Pharmacol 02-Dec-2022
PMCID:PMC9755338
doi:10.3389/fphar.2022.1025591
PMID:36532778
Synthesis, Anti-Influenza H1N1 and Anti-Dengue Activity of A-Ring Modified Oleanonic Acid Polyamine Derivatives Smirnova I, Petrova A, Giniyatullina G, Smirnova A, Volobueva A, Pavlyukova J, Zarubaev V, Loc TV, Tran Thi Phoung T, Hau VT, Thuy NT, Khine MM, Kazakova O Molecules 02-Dec-2022
PMCID:PMC9738632
doi:10.3390/molecules27238499
PMID:36500593
Allelopathic Properties of Lamiaceae Species: Prospects and Challenges to Use in Agriculture Islam AK, Suttiyut T, Anwar MP, Juraimi AS, Kato-Noguchi H Plants (Basel) 31-May-2022
PMCID:PMC9182988
doi:10.3390/plants11111478
PMID:35684250
Inventorization and Consensus Analysis of Ethnoveterinary Medicinal Knowledge Among the Local People in Eastern India: Perception, Cultural Significance, and Resilience Mandal SK, Rahaman CH Front Pharmacol 29-Apr-2022
PMCID:PMC9099233
doi:10.3389/fphar.2022.861577
PMID:35571138
In Vitro Antiviral Activity of Potential Medicinal Plant Extracts Against Dengue and Chikungunya Viruses Alagarasu K, Patil P, Kaushik M, Chowdhury D, Joshi RK, Hegde HV, Kakade MB, Hoti SL, Cherian S, Parashar D Front Cell Infect Microbiol 07-Apr-2022
PMCID:PMC9021897
doi:10.3389/fcimb.2022.866452
PMID:35463636
Traditions for Future Cross-National Food Security—Food and Foraging Practices among Different Native Communities in the Western Himalayas Haq SM, Hassan M, Jan HA, Al-Ghamdi AA, Ahmad K, Abbasi AM Biology (Basel) 16-Mar-2022
PMCID:PMC8944997
doi:10.3390/biology11030455
PMID:35336828
Phytochemical Investigation and Determination of Antibacterial Activity of Solvent Leave Extracts of Carissa spinarum Ayalew Tiruneh T, Ayalew Tiruneh G, Chekol Abebe E, Mengie Ayele T Infect Drug Resist 04-Mar-2022
PMCID:PMC8904435
doi:10.2147/IDR.S352049
PMID:35281572
Comprehensive Phytochemical Profiling of Polyherbal Divya-Kayakalp-Vati and Divya-Kayakalp-Oil and Their Combined Efficacy in Mouse Model of Atopic Dermatitis-Like Inflammation Through Regulation of Cytokines Balkrishna A, Verma S, Sakat S, Joshi K, Solleti SK, Bhattacharya K, Varshney A Clin Cosmet Investig Dermatol 23-Feb-2022
PMCID:PMC8882669
doi:10.2147/CCID.S342227
PMID:35237058
A review through therapeutic attributes of Ayurvedic formulation mashi Joshi A, Baheti A, Wani M, Nimbalkar R J Ayurveda Integr Med 12-Nov-2021
PMCID:PMC8642712
doi:10.1016/j.jaim.2021.06.018
PMID:34776325
Modulation of psoriatic-like skin inflammation by traditional Indian medicine Divya-Kayakalp-Vati and Oil through attenuation of pro-inflammatory cytokines Balkrishna A, Sakat S, Joshi K, Singh R, Verma S, Nain P, Bhattacharya K, Varshney A J Tradit Complement Med 20-Sep-2021
PMCID:PMC9210137
doi:10.1016/j.jtcme.2021.09.003
PMID:35747349
Anti-dengue activity of super critical extract and isolated oleanolic acid of Leucas cephalotes using in vitro and in silico approach Kaushik S, Dar L, Kaushik S, Yadav JP BMC Complement Med Ther 08-Sep-2021
PMCID:PMC8425015
doi:10.1186/s12906-021-03402-2
PMID:34496833
Tricin Biosynthesis and Bioengineering Lam PY, Lui AC, Wang L, Liu H, Umezawa T, Tobimatsu Y, Lo C Front Plant Sci 26-Aug-2021
PMCID:PMC8426635
doi:10.3389/fpls.2021.733198
PMID:34512707

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids
(1S,4aR,4bS,6R,7R,10aR)-6,7-dihydroxy-1,4a-dimethyl-7-propan-2-yl-3,4,4b,5,6,8,10,10a-octahydro-2H-phenanthrene-1-carboxylic acid 163191356 Click to see CC(C)C1(CC2=CCC3C(C2CC1O)(CCCC3(C)C(=O)O)C)O 336.50 unknown https://doi.org/10.1248/CPB.54.1370
6,7-dihydroxy-1,4a-dimethyl-7-propan-2-yl-3,4,4b,5,6,8,10,10a-octahydro-2H-phenanthrene-1-carboxylic acid 162960711 Click to see 336.50 unknown https://doi.org/10.1248/CPB.54.1370
CID 163069153 163069153 Click to see CC1CC(C2C(C(CCC2(C13CCC4(O3)CCOC4OC(=O)C)C)OC(=O)C)(C)C)OC=O 466.60 unknown https://doi.org/10.1248/CPB.54.1370
CID 91516665 91516665 Click to see CC1CC(C2C(C(CCC2(C13CCC4(O3)CCOC4OC(=O)C)C)OC(=O)C)(C)C)OC=O 466.60 unknown https://doi.org/10.1248/CPB.54.1370
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(2S,5S)-2-[(3S,5R,8S,9S,10R,13S,14S,17S)-3-hydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-6-ene-2,5-diol 101412157 Click to see CC(=C)C(CCC(C)(C1CCC2(C1CCC3C2(CCC4C3(CCC(C4(C)C)O)C)C)C)O)O 460.70 unknown https://doi.org/10.1248/CPB.54.1370
17-(2-hydroxy-5,6-dimethylhept-6-en-2-yl)-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 12302470 Click to see 458.80 unknown https://doi.org/10.1248/CPB.54.1370
2-(3-hydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-6-methylhept-6-ene-2,5-diol 72999868 Click to see 460.70 unknown https://doi.org/10.1248/CPB.54.1370
3-Hydroxyolean-12-en-28-oic acid 619166 Click to see 456.70 unknown https://doi.org/10.1248/CPB.54.1370
Leucastrin A 101412156 Click to see 458.80 unknown https://doi.org/10.1248/CPB.54.1370
Oleanolic Acid 10494 Click to see 456.70 unknown https://doi.org/10.1248/CPB.54.1370
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
14-(5-Ethyl-6-methylheptan-2-yl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-ene-5,9-diol 5318414 Click to see 430.70 unknown https://doi.org/10.1248/CPB.54.1370
14-(5-Ethyl-6-methylheptan-2-yl)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-9-one 14779505 Click to see 428.70 unknown https://doi.org/10.1248/CPB.54.1370
17-(5-ethyl-6-methylhept-3-en-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 122544 Click to see 412.70 unknown https://doi.org/10.1248/CPB.54.1370
17-(5-ethyl-6-methylhept-3-en-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol 73834225 Click to see 428.70 unknown https://doi.org/10.1248/CPB.54.1370
17-(5-Ethyl-6-methylhept-3-en-2-yl)-3-hydroxy-10,13-dimethyl-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one 72607933 Click to see CCC(C=CC(C)C1CCC2C1(CCC3C2C(=O)C=C4C3(CCC(C4)O)C)C)C(C)C 426.70 unknown https://doi.org/10.1248/CPB.54.1370
17-(5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 86821 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown https://doi.org/10.3109/13880206909066289
3-Hydroxystigmast-5-en-7-one 160608 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2C(=O)C=C4C3(CCC(C4)O)C)C)C(C)C 428.70 unknown https://doi.org/10.1248/CPB.54.1370
7-Ketostigmasterol 12044013 Click to see 426.70 unknown https://doi.org/10.1248/CPB.54.1370
7alpha-Hydroxysitosterol 161816 Click to see 430.70 unknown https://doi.org/10.1248/CPB.54.1370
7alpha-Hydroxystigmasterol 21769896 Click to see 428.70 unknown https://doi.org/10.1248/CPB.54.1370
Stigmast-5-en-3-ol 22012 Click to see 414.70 unknown https://doi.org/10.3109/13880206909066289
Stigmasterol 5280794 Click to see 412.70 unknown https://doi.org/10.1248/CPB.54.1370
> Organic acids and derivatives / Carboxylic acids and derivatives / Tricarboxylic acids and derivatives
(8-formyloxy-1,1,4a,6-tetramethyl-5'-oxospiro[3,4,6,7,8,8a-hexahydro-2H-naphthalene-5,2'-oxolane]-2-yl) acetate 162888849 Click to see 366.40 unknown https://doi.org/10.1248/CPB.54.1370
[(2S,4aS,5R,6R,8R,8aS)-8-formyloxy-1,1,4a,6-tetramethyl-5'-oxospiro[3,4,6,7,8,8a-hexahydro-2H-naphthalene-5,2'-oxolane]-2-yl] acetate 101412154 Click to see 366.40 unknown https://doi.org/10.1248/CPB.54.1370
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glucuronides
(2S,3S,4S,5R,6S)-6-[4-(5,7-dihydroxy-4-oxochromen-2-yl)-2-hydroxyphenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid 56776218 Click to see 462.40 unknown https://doi.org/10.1248/CPB.54.1370
6-[4-(5,7-Dihydroxy-4-oxochromen-2-yl)-2-hydroxyphenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid 76401243 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)OC4C(C(C(C(O4)C(=O)O)O)O)O 462.40 unknown https://doi.org/10.1248/CPB.54.1370
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides
[3,4,5-Trihydroxy-6-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxan-2-yl]methyl 3-(4-hydroxyphenyl)prop-2-enoate 162916367 Click to see 578.50 unknown https://doi.org/10.1248/CPB.54.1370
Anisofolin A 21721971 Click to see 724.70 unknown https://doi.org/10.1248/CPB.54.1370
Apigenin 7-O-glucoside 5280704 Click to see 432.40 unknown https://doi.org/10.1248/CPB.54.1370
Apigenin-7-O-(6''-O-4-coumaroyl)-beta-glucopyranoside 6439941 Click to see 578.50 unknown https://doi.org/10.1248/CPB.54.1370
CID 73829948 73829948 Click to see C1=CC(=CC=C1C=CC(=O)OCC2C(C(C(C(O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC=C(C=C5)O)O)O)OC(=O)C=CC6=CC=C(C=C6)O)O)O 724.70 unknown https://doi.org/10.1248/CPB.54.1370
Npc85473 5385553 Click to see 432.40 unknown https://doi.org/10.1248/CPB.54.1370
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 3-O-methylated flavonoids
Tricin 5281702 Click to see COC1=CC(=CC(=C1O)OC)C2=CC(=O)C3=C(C=C(C=C3O2)O)O 330.29 unknown https://doi.org/10.1248/CPB.54.1370
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids
3',5-Dihydroxy-4',7-dimethoxyflavone 5320496 Click to see 314.29 unknown https://doi.org/10.1248/CPB.54.1370
5-Hydroxy-7,4'-dimethoxyflavone 5281601 Click to see 298.29 unknown https://doi.org/10.1248/CPB.54.1370
Gonzalitosin I 5272653 Click to see 328.30 unknown https://doi.org/10.1248/CPB.54.1370

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