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Isodon ternifolius

Table of Contents

Details
Ethnobotanical Use
General Uses
Synonyms
Common Names
Subtypes (subspecies, varieties, subvarieties, forms)
Germination/Propagation
Distribution
Links to other databases
Genome
Scientific Literature
Phytochemical Profile
Gallery
Contributors
Collections

Details Top

Internal ID UUID643fdf84c0152188368250
Scientific name Isodon ternifolius
Authority (D.Don) Kudô
First published in Mem. Fac. Sci. Taihoku Imp. Univ. 2: 140 (1929)

Ethnobotanical Use Top

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General Uses Top

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Scientific uses:
Isodon ternifolius is used as a research subject in phytochemistry and natural products studies. Extracts and isolated diterpenoids from aerial parts have been employed in laboratory investigations to explore chemical diversity and biosynthetic relationships among Isodon (Lamiaceae) constituents. No established commercial, industrial, culinary, craft, or fragrance uses are reported; no standardized timber, fiber, colorant, gum/resin, food, or cosmetic applications are documented.

Synonyms Top

Scientific name Authority First published in
Ocimum ternifolium Spreng. Syst. Veg. 4(2): 224 (1827)
Plectranthus buckia Buch.-Ham. ex D.Don Prodr. Fl. Nepal. : 117 (1825)
Plectranthus hosseusii Muschl. Repert. Spec. Nov. Regni Veg. 4: 268 (1907)
Plectranthus ternifolius D.Don Prodr. Fl. Nepal. : 117 (1825)
Rabdosia ternifolia (D.Don) H.Hara J. Jap. Bot. 47: 201 (1972)
Rabdosiella ternifolia (D.Don) Codd Bothalia 15: 10 (1984)
Teucrium esquirolii H.Lév. Bull. Acad. Int. Géogr. Bot. 22: 236 (1912)
Elsholtzia lychnitis H.Lév. & Vaniot Repert. Spec. Nov. Regni Veg. 8: 425 (1910)
Elsholtzia thompsonii Hook.f. Fl. Brit. India 4: 643 (1885)

Common names Top

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Language Common/alternative name
Thai ผักอีหลืน
Chinese 牛尾草
Chinese 伤寒头
Chinese 牛尾巴蒿
Chinese 扫帚草

Subspecies (abbr. subsp./ssp.) Top

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No subspecies added yet.

Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • Arabian Peninsula
      • Saudi Arabia
    • China
      • China South-central
      • China Southeast
  • Asia-tropical
    • Indian Subcontinent
      • Assam
      • Bangladesh
      • East Himalaya
      • Nepal
      • West Himalaya
    • Indo-China
      • Laos
      • Myanmar
      • Thailand
      • Vietnam

Links to other databases Top

Suggest others/fix!
Database ID/link to page
World Flora Online wfo-0000217983
Tropicos 17607167
KEW urn:lsid:ipni.org:names:448620-1
The Plant List kew-103045
Open Tree Of Life 23549
NCBI Taxonomy 204136
IPNI 448620-1
GBIF 5608825
EOL 2898995

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
NcRNA Regulated Pyroptosis in Liver Diseases and Traditional Chinese Medicine Intervention: A Narrative Review Deng J, Qin L, Qin S, Wu R, Huang G, Fang Y, Huang L, Zhou Z J Inflamm Res 03-Apr-2024
PMCID:PMC10999193
doi:10.2147/JIR.S448723
PMID:38585470
A Comprehensive Review of the Classification, Sources, Phytochemistry, and Pharmacology of Norditerpenes Zeng N, Zhang Q, Yao Q, Fu G, Su W, Wang W, Li B Molecules 21-Dec-2023
PMCID:PMC10780140
doi:10.3390/molecules29010060
PMID:38202643
Ethnobotanical, Phytochemical, and Pharmacological Properties of the Subfamily Nepetoideae (Lamiaceae) in Inflammatory Diseases Ortiz-Mendoza N, Martínez-Gordillo MJ, Martínez-Ambriz E, Basurto-Peña FA, González-Trujano ME, Aguirre-Hernández E Plants (Basel) 02-Nov-2023
PMCID:PMC10648697
doi:10.3390/plants12213752
PMID:37960108
Network Pharmacology and Molecular Docking Reveal the Mechanism of Isodon ternifolius (D. Don) Kudo Against Liver Fibrosis Deng J, Qin L, Zhou Z Drug Des Devel Ther 07-Aug-2023
PMCID:PMC10416792
doi:10.2147/DDDT.S412818
PMID:37576085
Ternifolipyrons A–J: new cytotoxic α-pyrones from Isodon ternifolius (D. Don) Kudô Elshamy AI, Mohamed TA, Swapana N, Kasai Y, Noji M, Efferth T, Imagawa H, Hegazy ME, Umeyama A RSC Adv 29-Jun-2023
PMCID:PMC10309080
doi:10.1039/d3ra03146b
PMID:37396835
Small-molecule compounds inhibiting S-phase kinase-associated protein 2: A review Jing J, Rui L, Junyuan S, Jinfeng Y, Zhihao H, Weiguo L, Zhenyu J Front Pharmacol 05-Apr-2023
PMCID:PMC10113621
doi:10.3389/fphar.2023.1122008
PMID:37089937
Plant Species as Potential Forage for Honey Bees in the Al-Baha Mountain Region in Southwestern Saudi Arabia Al-Ghamdi AA, Al-Sagheer NA Plants (Basel) 22-Mar-2023
PMCID:PMC10058344
doi:10.3390/plants12061402
PMID:36987090
Synthesis and biological activities of 11- and 12-substituted benzophenanthridinone derivatives as DNA topoisomerase IB and tyrosyl-DNA phosphodiesterase 1 inhibitors Yang H, Qin C, Wu M, Wang FT, Wang W, Agama K, Pommier Y, Hu DX, An LK ChemMedChem 17-Mar-2023
PMCID:PMC10233710
doi:10.1002/cmdc.202200593
PMID:36932053
Plastome sequences fail to resolve shallow level relationships within the rapidly radiated genus Isodon (Lamiaceae) Chen YP, Zhao F, Paton AJ, Sunojkumar P, Gao LM, Xiang CL Front Plant Sci 08-Sep-2022
PMCID:PMC9493350
doi:10.3389/fpls.2022.985488
PMID:36160976
Recent Progress in Understanding the Action of Natural Compounds at Novel Therapeutic Drug Targets for the Treatment of Liver Cancer Zheng Y, Zhang W, Xu L, Zhou H, Yuan M, Xu H Front Oncol 26-Jan-2022
PMCID:PMC8825370
doi:10.3389/fonc.2021.795548
PMID:35155196
Molecular Mechanisms of Antiproliferative Effects of Natural Chalcones Michalkova R, Mirossay L, Gazdova M, Kello M, Mojzis J Cancers (Basel) 31-May-2021
PMCID:PMC8198114
doi:10.3390/cancers13112730
PMID:34073042
Synthesis of Methoxy-, Methylenedioxy-, Hydroxy-, and Halo-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Inhibitors and Their Biological Activity for Drug-Resistant Cancer Hu DX, Tang WL, Zhang Y, Yang H, Wang W, Agama K, Pommier Y, An LK J Med Chem 19-May-2021
PMCID:PMC10087287
doi:10.1021/acs.jmedchem.1c00318
PMID:34008967
In Silico Studies of Lamiaceae Diterpenes with Bioinsecticide Potential against Aphis gossypii and Drosophila melanogaster Rodrigues GC, dos Santos Maia M, Silva Cavalcanti AB, de Sousa NF, Scotti MT, Scotti L Molecules 02-Feb-2021
PMCID:PMC7867283
doi:10.3390/molecules26030766
PMID:33540716
An updated tribal classification of Lamiaceae based on plastome phylogenomics Zhao F, Chen YP, Salmaki Y, Drew BT, Wilson TC, Scheen AC, Celep F, Bräuchler C, Bendiksby M, Wang Q, Min DZ, Peng H, Olmstead RG, Li B, Xiang CL BMC Biol 08-Jan-2021
PMCID:PMC7796571
doi:10.1186/s12915-020-00931-z
PMID:33419433
Molecular and morphological evidence for a new species of Isodon (Lamiaceae) from southern China Chen YP, Huang CZ, Zhao Y, Xiang CL Plant Divers 14-Jul-2020
PMCID:PMC7987569
doi:10.1016/j.pld.2020.06.004
PMID:33778225

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Kaurane diterpenoids
(1R,2S,3S,5S,8S,9S,10S,11R,15S,16R)-3,9,10,15-tetrahydroxy-16-methoxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one 101536712 Click to see 394.50 unknown https://doi.org/10.1016/0031-9422(79)80075-8
https://doi.org/10.1016/S0031-9422(00)86887-9
(1R,2S,5S,8R,9S,10S,11R,15S,16R,18R)-9,10,15,18-tetrahydroxy-16-methoxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one 101663493 Click to see 394.50 unknown https://doi.org/10.1016/0031-9422(79)80075-8
https://doi.org/10.1016/S0031-9422(01)00245-X
https://doi.org/10.1016/S0031-9422(00)86887-9
(1R,2S,5S,8R,9S,11S,13S,14S,15R,19S)-13,14,19-trihydroxy-16,16-dimethyl-6-methylidene-10,12-dioxahexacyclo[9.8.0.01,15.02,8.05,9.08,13]nonadecan-7-one 92484182 Click to see 362.40 unknown https://doi.org/10.1248/CPB.38.439
https://doi.org/10.1248/CPB.38.1877
(1S,2S,3S,5S,8S,10S,11R,15S,16S)-3,9,10,15-tetrahydroxy-16-methoxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one 163193242 Click to see 394.50 unknown https://doi.org/10.1016/S0031-9422(01)00245-X
(1S,2S,3S,5S,8S,9S,10S,11R,15S,16S)-3,9,10,15-tetrahydroxy-16-methoxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one 162991288 Click to see 394.50 unknown https://doi.org/10.1016/S0031-9422(01)00245-X
(1S,2S,5S,8R,10S,11R,15S,16S,18S)-9,10,15,18-tetrahydroxy-16-methoxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one 163186924 Click to see CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3OC)O)O)O)C 394.50 unknown https://doi.org/10.1016/S0031-9422(01)00245-X
(1S,2S,5S,8R,9S,10S,11R,15S,16S,18S)-9,10,15,18-tetrahydroxy-16-methoxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one 162895116 Click to see CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3OC)O)O)O)C 394.50 unknown https://doi.org/10.1016/S0031-9422(01)00245-X
(1S,2S,8R,9S,11R)-9,10,15,18-tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one 138107787 Click to see 364.40 unknown https://doi.org/10.1248/CPB.38.439
(2S,3S,5S,8S,9S,10S,11R,15S)-3,9,10,15-tetrahydroxy-16-methoxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one 101663495 Click to see 394.50 unknown https://doi.org/10.1016/S0031-9422(00)86887-9
(2S,5S,8R,13R,14S,15R)-13,14,19-trihydroxy-16,16-dimethyl-6-methylidene-10,12-dioxahexacyclo[9.8.0.01,15.02,8.05,9.08,13]nonadecan-7-one 5320676 Click to see CC1(CCC(C23C1C(C4(C56C2CCC(C5OC3O4)C(=C)C6=O)O)O)O)C 362.40 unknown https://doi.org/10.1248/CPB.38.439
(3,7,9,18-Tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-10-yl) acetate 162960908 Click to see 408.50 unknown https://doi.org/10.1016/S0031-9422(00)86887-9
(7-Acetyloxy-9,18-dihydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-10-yl) acetate 14564531 Click to see CC(=O)OC1C2C(CCCC23COC1(C45C3CCC(C4O)C(=C)C5OC(=O)C)O)(C)C 434.50 unknown https://doi.org/10.1248/CPB.38.1877
https://doi.org/10.1248/CPB.38.439
[(1R,2S,3S,5S,7R,8S,9S,10S,11R,15S)-7,9,10,15-tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-3-yl] acetate 101306770 Click to see CC(=O)OC1CC2CC3(C1C45COC3(C(C4C(CCC5O)(C)C)O)O)C(C2=C)O 408.50 unknown https://doi.org/10.1016/0031-9422(90)87132-E
[(1R,2S,3S,5S,7R,8S,9S,10S,11R)-3,7,9-trihydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-10-yl] acetate 163058245 Click to see 392.50 unknown https://doi.org/10.1016/0031-9422(79)80075-8
https://doi.org/10.1016/S0031-9422(00)86887-9
[(1R,2S,5S,7R,8R,9S,10S,11R,18R)-7-acetyloxy-9,18-dihydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-10-yl] acetate 101835386 Click to see 434.50 unknown https://doi.org/10.1248/CPB.38.439
[(1R,2S,5S,7R,8S,9S,10S,11R,18R)-7-acetyloxy-9,18-dihydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-10-yl] acetate 162845809 Click to see 434.50 unknown https://doi.org/10.1016/S0031-9422(01)00245-X
[(1R,2S,5S,7S,8R,9S,10S,11R,18R)-7-acetyloxy-9,18-dihydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-10-yl] acetate 162845810 Click to see 434.50 unknown https://doi.org/10.1248/CPB.38.439
https://doi.org/10.1248/CPB.38.1877
[(1S,2S,3S,5S,7R,8S,9S,10S,11R,18R)-3,7,9,18-tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-10-yl] acetate 162960911 Click to see 408.50 unknown https://doi.org/10.1016/S0031-9422(01)00245-X
[(2S,5S,7R,8S,9R,10S,11R)-7,10-diacetyloxy-9-hydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-3-yl] acetate 5318554 Click to see 476.60 unknown https://doi.org/10.1016/S0031-9422(01)00245-X
[(2S,5S,7R,8S,9R,10S,11R)-7,9,10-trihydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-3-yl] acetate 5318555 Click to see CC(=O)OC1CC2CC3(C1C45CCCC(C4C(C3(OC5)O)O)(C)C)C(C2=C)O 392.50 unknown https://doi.org/10.1016/S0031-9422(01)00245-X
13,14,19-Trihydroxy-16,16-dimethyl-6-methylidene-10,12-dioxahexacyclo[9.8.0.01,15.02,8.05,9.08,13]nonadecan-7-one 14564539 Click to see 362.40 unknown https://doi.org/10.1248/CPB.38.1877
https://doi.org/10.1248/CPB.38.439
3,9,10,15-Tetrahydroxy-16-methoxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one 162991285 Click to see 394.50 unknown https://doi.org/10.1016/S0031-9422(00)86887-9
https://doi.org/10.1016/0031-9422(79)80075-8
CID 101663494 101663494 Click to see 394.50 unknown https://doi.org/10.1016/S0031-9422(00)86887-9
Oridonin 5321010 Click to see CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3)O)O)O)C 364.40 unknown https://doi.org/10.1248/CPB.38.439
https://doi.org/10.1248/CPB.38.1877
Rabdoternin F 74317560 Click to see CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3OC)O)O)O)C 394.50 unknown https://doi.org/10.1016/S0031-9422(00)86887-9
https://doi.org/10.1016/0031-9422(79)80075-8
Rubescensin A 3576890 Click to see CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3)O)O)O)C 364.40 unknown https://doi.org/10.1248/CPB.38.1877
https://doi.org/10.1248/CPB.38.439
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Aromatic monoterpenoids
[2-(14-Cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyltetradeca-7,9,11,13-tetraenyl)-9-[3-[2-[4-[[4-(dimethylamino)-2,3-dihydroxy-5-methoxypentanoyl]amino]pentan-2-yl]-1,3-oxazol-4-yl]prop-2-enyl]-7-hydroxy-4,4,8-trimethyl-1,10-dioxaspiro[4.5]decan-3-yl] dihydrogen phosphate 73814017 Click to see CC1C(CC2(C(C(C(O2)C(CC(C(C)C(C(C)C=C(C)C(=CC=CC(=CC#N)C)C)O)O)OC)OP(=O)(O)O)(C)C)OC1CC=CC3=COC(=N3)C(C)CC(C)NC(=O)C(C(C(COC)N(C)C)O)O)O 1023.20 unknown https://doi.org/10.1016/0031-9422(79)80075-8
https://doi.org/10.1016/S0031-9422(00)86887-9
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Iridoids and derivatives
(1S,2R,3S,5R,6S)-2-methyl-5-[(1S)-1,2,2-trimethylcyclopentyl]-7-oxabicyclo[4.1.0]heptane-2,3-diol 11076002 Click to see CC1(CCCC1(C)C2CC(C(C3C2O3)(C)O)O)C 254.36 unknown https://doi.org/10.1248/CPB.38.439
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones / Diterpene lactones
(-)-Rabdoternin A 3086622 Click to see 364.40 unknown https://doi.org/10.1248/CPB.38.439
https://doi.org/10.1248/CPB.38.1877
(2R,5S,9S,10R,11R,15S,18R)-7,9,10,15,18-pentahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-16-one 101835385 Click to see CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5O)(OC3=O)O)O)O)C 380.40 unknown https://doi.org/10.1248/CPB.38.439
7,9,10,18-Tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-16-one 14564527 Click to see 364.40 unknown https://doi.org/10.1248/CPB.38.439
https://doi.org/10.1248/CPB.38.1877
Rabdoternin A 70698010 Click to see CC1(CCCC23C1C(C(C45C2CCC(C4O)C(=C)C5O)(OC3=O)O)O)C 364.40 unknown https://doi.org/10.1248/CPB.38.439
Rabdoternin B 3086623 Click to see CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5O)(OC3=O)O)O)O)C 380.40 unknown https://doi.org/10.1248/CPB.38.1877
https://doi.org/10.1248/CPB.38.439
> Organic acids and derivatives / Carboxylic acids and derivatives / Pentacarboxylic acids and derivatives
[(1R,3S,3aR,4R,5R,6R,7aS)-6-[(1S,2R,3R,4S,6S)-4-acetyloxy-6-hydroxy-2-(2-methoxy-2-oxoethyl)-1,3-dimethyl-7,9-dioxabicyclo[4.2.1]nonan-3-yl]-5-formyloxy-3-(furan-3-yl)-7a-hydroxy-3a-methyl-7-methylidene-1-propanoyloxy-1,2,3,4,5,6-hexahydroinden-4-yl] (2R,3R)-2-hydroxy-3-methylpentanoate 163190175 Click to see 778.80 unknown https://doi.org/10.1016/S0031-9422(01)00245-X
> Organic acids and derivatives / Carboxylic acids and derivatives / Tetracarboxylic acids and derivatives
[2-[3-(3,4-Diacetyloxypent-1-enyl)oxiran-2-yl]-6-oxo-2,3-dihydropyran-3-yl] acetate 433419 Click to see 382.40 unknown https://doi.org/10.1021/NP960689E
10-Epi-Olguine 6442294 Click to see 382.40 unknown https://doi.org/10.1021/NP960689E
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones
Gambospiroene 45268894 Click to see CC1=CCC2(CC1=O)C34C(CC=CC3C(=O)C5=C(C(=C(C(=C5O4)CC=C(C)C)O)CC=C(C)CCC=C(C)C)O)C(O2)(C)C 600.80 unknown https://doi.org/10.1248/CPB.38.1877
https://doi.org/10.1248/CPB.38.439

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