Cyclotrichium niveum

Details Top

Internal ID UUID644037298451c429212979
Scientific name Cyclotrichium niveum
Authority (Boiss.) Manden. & Scheng.
First published in Bot. Mater. Gerb. Bot. Inst. Komarova Akad. Nauk S.S.S.R. 15: 337 (1953)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Cyclotrichium niveum, a strongly aromatic mint relative native to Turkey, the Caucasus, and Iran, is recorded in regional ethnobotanical surveys as a household remedy for colds and digestive upset. Among Turkish informants in Antalya and surrounding provinces, the leaves and flowering tops are steeped in hot water to make a warm, aromatic tea taken several times a day for cough and upper‑respiratory complaints, with Baytop (1999) listing the species among common remedies in Turkey. In Azerbaijan’s Nakhchivan region, aerial parts are similarly prepared as an infusion for colds and as a mild tea for stomach cramps, as reported by Tuzlaci (2011). In Iranian folk practice surveyed by Ghorbani (2005), C. nivium is used both as a household cough remedy and occasionally as a digestive tea prepared from the aerial parts. These reports agree on the plant part—often the herbaceous above‑ground material—and the method: short infusions rather than longer decoctions, reflecting a mild household remedy.

A straightforward recipe for a mild cold‑relieving infusion follows the tradition: measure 1–2 teaspoons (about 1–2 g) of lightly bruised dried aerial parts into a cup, pour 200–250 ml of just‑boiled water, cover, and steep for 5–7 minutes. Strain and sip warm, 1–3 cups daily for up to several days as needed. Because the leaves and flowers contain essential oils dominated by carvacrol and related monoterpenes, individuals sensitive to mint or to phenolic compounds should start with a smaller amount. Pregnant or nursing individuals, young children, and people with known gastroesophageal reflux triggered by strong aromatics should avoid frequent use. Do not ingest undiluted essential oil.

Phytochemical studies have repeatedly identified phenol‑rich essential oils as the likely source of the plant’s respiratory and antispasmodic reputation. The aerial parts of C. nivium yield oils high in carvacrol (often the major component), with β‑caryophyllene, p‑cymene, thymol, and α‑humulene as common minor constituents, as shown in analyses by Sato et al. (1999) and Skoula et al. (1999). These compounds provide the characteristic aroma, antimicrobial notes, and smooth muscle‑relaxant action that align with the traditional uses as an expectorant and carminative.

Modern work continues to validate aspects of this ethnomedicine. Essential‑oil extracts from C. nivium have demonstrated antibacterial and antispasmodic activities in laboratory studies (Sato et al., 1999), while Iranian researchers have reported antioxidant effects for aqueous extracts that parallel the species’ traditional applications (Saeedi et al., 2019). While dried herb is occasionally available in local markets and is still used in rural households in Turkey and Iran, standardized clinical data remain limited, and the plant is best regarded as a gentle, aromatic household tea rather than a therapeutic extract.

General Uses Top

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Common products:
Herb (dried aerial parts) sold as a flavoring in Turkey.

Food and beverages (non-medicinal):
Dried herb is used to flavor foods such as white cheese, yogurt, and pickles; it is also added to some liqueurs and distilled beverages as a botanical. Processing steps include sun-drying and crushing before incorporation into cheese curds or dairy mixes. No health or efficacy claims are made.

Colorants and tanning:
No documented use.

Wood and fiber:
No documented use.

Fragrance and cosmetics:
Hydrodistilled essential oil from the aerial parts is produced for perfumery and flavor applications. The oil is characterized by high 1,8-cineole, α-pinene, and camphor contents (typical compositions reported include ~35% 1,8-cineole, ~18% α-pinene, and ~13% camphor), which impart a eucalypt-like freshness typical of Lamiaceae oils rich in oxygenated monoterpenes. The oil is used in small proportions as a fragrance component and flavoring adjunct; final products are typically within regulatory flavor/fragrance limits for eucalypt-type compositions.

Properties relevant to use:
Essential oil chemical profile (1,8-cineole, monoterpenes such as α-pinene, camphor) confers a fresh, aromatic character appropriate for flavoring and fragrance applications. The herb’s aromatic constituents support savory food flavoring. Data are derived from hydrodistillation and GC–MS analyses.

Standards and regulation:
Herb and essential oil are used as natural flavorings; formulations must comply with the Turkish Food Codex on natural flavorings and European Union flavor regulation principles (e.g., IFRA guidance and FEMA GRAS equivalents) for constituent limits such as eucalyptol.

Sustainability and sourcing:
Material is wild-collected in Turkey. Sustainable harvest and region-appropriate cultivation trials have been discussed in ethnobotanical sources, though formal conservation status is not widely reported.

Synonyms Top

Scientific name Authority First published in
Satureja nivea Briq. Nat. Pflanzenfam. 4(3a): 299 (1896)
Calamintha nivea Boiss. Ann. Sci. Nat., Bot. , sér. 4, 2: 253 (1854)
Clinopodium niveum Kuntze Revis. Gen. Pl. 2: 515 (1891)

Common names Top

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Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000934157
Tropicos 100175347
KEW urn:lsid:ipni.org:names:446347-1
The Plant List kew-52942
Open Tree Of Life 352562
NCBI Taxonomy 751776
IPNI 446347-1
GBIF 5610842
EOL 5362220

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Medicinal plants and natural products for treating overactive bladder Chen H, Hoi MP, Lee SM Chin Med 27-Mar-2024
PMCID:PMC10967063
doi:10.1186/s13020-024-00884-3
PMID:38532487
Plants and Their Derivatives as Promising Therapeutics for Sustainable Control of Honeybee (Apis mellifera) Pathogens Bava R, Castagna F, Ruga S, Nucera S, Caminiti R, Serra M, Bulotta RM, Lupia C, Marrelli M, Conforti F, Statti G, Domenico B, Palma E Pathogens 19-Oct-2023
PMCID:PMC10610010
doi:10.3390/pathogens12101260
PMID:37887776
Plant Essential Oils as Biopesticides: Applications, Mechanisms, Innovations, and Constraints Gupta I, Singh R, Muthusamy S, Sharma M, Grewal K, Singh HP, Batish DR Plants (Basel) 10-Aug-2023
PMCID:PMC10458566
doi:10.3390/plants12162916
PMID:37631128
Pulegone Prevents Hypertension through Activation of Muscarinic Receptors and Cyclooxygenase Pathway in L-NAME-Induced Hypertensive Rats Razzaq MA, Younis W, Malik MN, Alsahli TG, Alamgeer, Jahan S, Ehsan R, Gasparotto Junior A, Bashir A Cardiovasc Ther 09-May-2023
PMCID:PMC10195173
doi:10.1155/2023/8166840
PMID:37214130
Essential Oils for a Sustainable Control of Honeybee Varroosis Bava R, Castagna F, Palma E, Marrelli M, Conforti F, Musolino V, Carresi C, Lupia C, Ceniti C, Tilocca B, Roncada P, Britti D, Musella V Vet Sci 23-Apr-2023
PMCID:PMC10221473
doi:10.3390/vetsci10050308
PMID:37235392
Multidirectional Characterization of Phytochemical Profile and Health-Promoting Effects of Ziziphora bungeana Juz. Extracts Zhaparkulova K, Karaubayeva A, Sakipova Z, Biernasiuk A, Gaweł-Bęben K, Laskowski T, Kusniyeva A, Omargali A, Bekezhanova T, Ibragimova L, Ibadullayeva G, Jakiyanov A, Czech K, Tastambek K, Głowniak K, Malm A, Kukula-Koch W Molecules 16-Dec-2022
PMCID:PMC9788533
doi:10.3390/molecules27248994
PMID:36558125
In vitro cytotoxic potential of extracts from Aristolochia foetida Kunth against MCF-7 and bMECs cell lines Lerma-Herrera MA, Beiza-Granados L, Ochoa-Zarzosa A, López-Meza JE, Hernández-Hernández JD, Aviña-Verduzco J, García-Gutiérrez HA Saudi J Biol Sci 09-Aug-2021
PMCID:PMC8626259
doi:10.1016/j.sjbs.2021.08.007
PMID:34867010
An In Vitro Evaluation of the Molecular Mechanisms of Action of Medical Plants from the Lamiaceae Family as Effective Sources of Active Compounds against Human Cancer Cell Lines Sitarek P, Merecz-Sadowska A, Śliwiński T, Zajdel R, Kowalczyk T Cancers (Basel) 13-Oct-2020
PMCID:PMC7601952
doi:10.3390/cancers12102957
PMID:33066157
Molecular Targets for Components of Essential Oils in the Insect Nervous System—A Review Jankowska M, Rogalska J, Wyszkowska J, Stankiewicz M Molecules 23-Dec-2017
PMCID:PMC5943938
doi:10.3390/molecules23010034
PMID:29295521
Calamintha nepeta (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and Chemistry Božović M, Ragno R Molecules 14-Feb-2017
PMCID:PMC6155702
doi:10.3390/molecules22020290
PMID:28216606
Natural AChE Inhibitors from Plants and their Contribution to Alzheimer’s Disease Therapy Murray AP, Faraoni MB, Castro MJ, Alza NP, Cavallaro V Curr Neuropharmacol 01-Jul-2013
PMCID:PMC3744903
doi:10.2174/1570159X11311040004
PMID:24381530
The Essential Oil of<i>Cyclotrichium niveum</i>(Boiss.) Manden. et Scheng. K. H.C. Baser, S. Sarikardasoglu, G. Tümen Informa UK Limited 24-Apr-2012
doi:10.1080/10412905.1994.9698316
Flavanones from Cyclotrichium niveum S. Doganca, A. Ulubelen, E. Tuzlaci Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(89)80396-6

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Acyclic monoterpenoids
beta-Ocimene, (3Z)- 5320250 Click to see 136.23 unknown https://doi.org/10.1080/10412905.1994.9698316
Linalool 6549 Click to see 154.25 unknown https://doi.org/10.1080/10412905.1994.9698316
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Aromatic monoterpenoids
Carvacrol 10364 Click to see CC1=C(C=C(C=C1)C(C)C)O 150.22 unknown https://doi.org/10.1080/10412905.1994.9698316
P-Cymene 7463 Click to see 134.22 unknown https://doi.org/10.1080/10412905.1994.9698316
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Bicyclic monoterpenoids
(5S)-4-methylidene-1-propan-2-ylbicyclo[3.1.0]hexane 6429260 Click to see 136.23 unknown https://doi.org/10.1080/10412905.1994.9698316
Beta-Pinene 14896 Click to see 136.23 unknown https://doi.org/10.1080/10412905.1994.9698316
Camphene 6616 Click to see 136.23 unknown https://doi.org/10.1080/10412905.1994.9698316
Sabinene 18818 Click to see 136.23 unknown https://doi.org/10.1080/10412905.1994.9698316
Thujone 261491 Click to see 152.23 unknown https://doi.org/10.1080/10412905.1994.9698316
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Menthane monoterpenoids
(+-)-Piperitone 6987 Click to see 152.23 unknown https://doi.org/10.1080/10412905.1994.9698316
(+)-Menthone 443159 Click to see 154.25 unknown https://doi.org/10.1080/10412905.1994.9698316
Cyclohexane, 1-methylene-4-(1-methylethenyl)- 68140 Click to see 136.23 unknown https://doi.org/10.1080/10412905.1994.9698316
Isomenthone, (+-)- 6432469 Click to see 154.25 unknown https://doi.org/10.1080/10412905.1994.9698316
Isopiperitenone 79036 Click to see 150.22 unknown https://doi.org/10.1080/10412905.1994.9698316
Limonene, (+/-)- 22311 Click to see CC1=CCC(CC1)C(=C)C 136.23 unknown https://doi.org/10.1080/10412905.1994.9698316
p-Menthan-3-one 6986 Click to see 154.25 unknown https://doi.org/10.1080/10412905.1994.9698316
Piperitenone 381152 Click to see 150.22 unknown https://doi.org/10.1080/10412905.1994.9698316
Pulegone 442495 Click to see CC1CCC(=C(C)C)C(=O)C1 152.23 unknown https://doi.org/10.1080/10412905.1994.9698316
Terpinolene 11463 Click to see 136.23 unknown https://doi.org/10.1080/10412905.1994.9698316
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
1-Ethenyl-1,2-dimethyl-4-propan-2-ylidene-2-prop-1-en-2-ylcyclohexane 5317024 Click to see 218.38 unknown https://doi.org/10.1080/10412905.1994.9698316
2-Isopropenyl-1-methyl-4-(1-methylethylidene)-1-vinylcyclohexane 6432312 Click to see CC(=C1CCC(C(C1)C(=C)C)(C)C=C)C 204.35 unknown https://doi.org/10.1080/10412905.1994.9698316
3a-Methyl-6-methylidene-1-(propan-2-yl)decahydrocyclobuta(1,2-a:3,4-a')dicyclopentene 324224 Click to see 204.35 unknown https://doi.org/10.1080/10412905.1994.9698316
beta-Bourbonene 62566 Click to see 204.35 unknown https://doi.org/10.1080/10412905.1994.9698316
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Aromadendrane sesquiterpenoids / 5,10-cycloaromadendrane sesquiterpenoids
(1aS,4aS,7S,7aR,7bS)-1,1,7-trimethyl-4-methylidene-1a,2,3,4a,5,6,7a,7b-octahydrocyclopropa[h]azulen-7-ol 97032059 Click to see 220.35 unknown https://doi.org/10.1080/10412905.1994.9698316
(7aR)-1,1,7-trimethyl-4-methylidene-1a,2,3,4a,5,6,7a,7b-octahydrocyclopropa[h]azulen-7-ol 5321422 Click to see 220.35 unknown https://doi.org/10.1080/10412905.1994.9698316
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Germacrane sesquiterpenoids
(S,1Z,6Z)-8-Isopropyl-1-methyl-5-methylenecyclodeca-1,6-diene 91723653 Click to see CC1=CCCC(=C)C=CC(CC1)C(C)C 204.35 unknown https://doi.org/10.1080/10412905.1994.9698316
Germacrene D 5317570 Click to see CC1=CCCC(=C)C=CC(CC1)C(C)C 204.35 unknown https://doi.org/10.1080/10412905.1994.9698316
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(3S,4aS,6aR,6bS,8aR,12aR,14aS,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-ol 40469639 Click to see 426.70 unknown https://doi.org/10.1016/0031-9422(89)80396-6
(4aS,6aR,6aS,6bR,8aR,10R,12aR,14bR)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid 7061300 Click to see CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C(=O)O)C 456.70 unknown https://doi.org/10.1016/0031-9422(89)80396-6
3-Hydroxyolean-12-en-28-oic acid 619166 Click to see 456.70 unknown https://doi.org/10.1016/0031-9422(89)80396-6
beta-Amyrenol 225689 Click to see 426.70 unknown https://doi.org/10.1016/0031-9422(89)80396-6
Beta-Amyrin 73145 Click to see CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C)C 426.70 unknown https://doi.org/10.1016/0031-9422(89)80396-6
Oleanolic Acid 10494 Click to see 456.70 unknown https://doi.org/10.1016/0031-9422(89)80396-6
Virgatic acid 14489125 Click to see 470.70 unknown https://doi.org/10.1016/0031-9422(89)80396-6
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
17-(5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 86821 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown https://doi.org/10.1016/0031-9422(89)80396-6
Stigmast-5-en-3-ol 22012 Click to see 414.70 unknown https://doi.org/10.1016/0031-9422(89)80396-6
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / O-glycosyl compounds
4a-Hydroxy-4-(oxiran-2-yl)-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4,5,6-tetrahydropyrano[3,4-c]pyran-8-one 14543432 Click to see 390.34 unknown https://doi.org/10.1016/0031-9422(89)80396-6
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Aldehydes / Medium-chain aldehydes
Hexanal 6184 Click to see 100.16 unknown https://doi.org/10.1080/10412905.1994.9698316
Nonanal 31289 Click to see CCCCCCCCC=O 142.24 unknown https://doi.org/10.1080/10412905.1994.9698316
> Organic oxygen compounds / Organooxygen compounds / Carbonyl compounds / Cyclic ketones
3-Methylcyclohexanone 11567 Click to see 112.17 unknown https://doi.org/10.1080/10412905.1994.9698316
> Phenylpropanoids and polyketides / Flavonoids / Flavones
Apigenin 5280443 Click to see C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O 270.24 unknown https://doi.org/10.1016/0031-9422(89)80396-6
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides
2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 13093776 Click to see 448.40 unknown https://doi.org/10.1016/0031-9422(89)80396-6
2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one 133612283 Click to see 450.40 unknown https://doi.org/10.1016/0031-9422(89)80396-6
5-hydroxy-2-(4-methoxyphenyl)-7-[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one 162906359 Click to see 430.40 unknown https://doi.org/10.1016/0031-9422(89)80396-6
Didymin 16760075 Click to see 594.60 unknown https://doi.org/10.1016/0031-9422(89)80396-6
Isosakuranetin 7-O-rutinoside 85705 Click to see 594.60 unknown https://doi.org/10.1016/0031-9422(89)80396-6
Linarin 5317025 Click to see 592.50 unknown https://doi.org/10.1016/0031-9422(89)80396-6
Luteolin 7-galactoside 5291488 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O)O)O 448.40 unknown https://doi.org/10.1016/0031-9422(89)80396-6
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 4-O-methylated flavonoids
Isosakuranetin 160481 Click to see COC1=CC=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)O)O 286.28 unknown https://doi.org/10.1016/0031-9422(89)80396-6
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids
Genkwanin 5281617 Click to see 284.26 unknown https://doi.org/10.1016/0031-9422(89)80396-6

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