Details Top

Internal ID UUID643fd6c8e84a8179011289
Scientific name Desmodium canadense
Authority (L.) DC.
First published in Prodr.2: 328 (1825)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Among Indigenous peoples of North America, Desmodium canadense has been recorded as a medicinal plant in several ethnobotanical surveys. The Anishinaabe (Ojibwe) of the Great Lakes prepared an infusion of the aerial parts – about a teaspoon of dried leaves – to ease coughs and colds, a practice reported by Moerman (1998). The Haudenosaunee (Iroquois) of New York and Ontario used a decoction of the roots to treat dysentery and abdominal pain, again noted by Moerman (1998). The Cherokee of the southeastern United States made a poultice of fresh leaves applied directly to minor cuts and bruises, a use listed by Foster and Duke (1990). In each case the preparation was simple: a tea for internal complaints and a cold poultice for external lesions.

In modern practice a mild leaf tea can be made by steeping one teaspoon (≈2 g) of dried Desmodium canadense leaves in 250 mL of just‑boiled water for 5–10 minutes, then straining. The resulting beverage is mildly astringent and traditionally taken warm, up to two cups a day for occasional respiratory discomfort. A typical dose is one cup (≈250 mL) two to three times daily for no more than five consecutive days, after which the tea should be discontinued. Because safety data are limited, the preparation is generally not recommended for pregnant or nursing women, and excessive use may cause mild gastrointestinal upset; a health professional should be consulted before regular consumption. The dried leaves keep best in a sealed, dark container to preserve their flavonoid content.

Phytochemical analyses of the species report a characteristic mix of flavonoids—quercetin and kaempferol—along with the isoflavones daidzein and genistein, phenolic acids such as caffeic acid, and polymeric tannins. These compounds are documented for Desmodium canadense in the USDA Phytochemical Database (2022) and are known to possess antioxidant and anti‑inflammatory properties that plausibly support the traditional therapeutic applications. A single cup of the tea supplies roughly 2–3 mg of total flavonoids, based on the typical content reported in the database.

While clinical trials have not yet been conducted, recent in‑vitro studies have suggested that extracts of the plant can inhibit inflammatory markers, and a small number of specialty herbal tea blends now list D. canadense as an ingredient marketed as a seasonal “tonic.” The species continues to be used in small‑scale traditional preparations by a few Anishinaabe families, and ongoing research is focused on clarifying its antioxidant capacity and exploring potential applications in modern phytotherapy.

General Uses Top

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Common products:
Leaf and stem material used as forage and hay for livestock; seed used as wildlife feed (especially waterfowl and songbirds); vegetative cuttings used in erosion control and revegetation mixes.

Industrial and craft applications:
In ecological restoration and stabilization seeding programs, aerial sowing and hydroseeding of cleared rights-of-way; plantings in riparian and prairie buffers for soil and bank stabilization.

Food and beverages (non-medicinal):
No established food/beverage uses documented for this taxon beyond wildlife feed. The species is occasionally grown for human ethnobotanical interest but lacks commercial food use.

Colorants and tanning:
No documented tannin or dye use reported for this species.

Wood and fiber:
Herbaceous growth habit precludes timber, lumber, or fiber products.

Fragrance and cosmetics:
No documented fragrance, essential oil, or cosmetic use.

Properties relevant to use:
Nodulation by rhizobia enables biological nitrogen fixation; palatability varies seasonally; foliage provides seasonal forage value and cut material yields reasonable hay quality.

Standards and regulation:
No product-specific standards identified; forage and restoration usage follows general agronomic and wildlife-seed purity and germination standards.

Sustainability and sourcing:
Propagated from seed; supports native pollinators and provides cover/food for wildlife; common in native seed mixes for prairie and wetland restoration; readily established from seed in temperate habitats. Wild collection can reduce stand vigor and should be avoided.

Synonyms Top

Scientific name Authority First published in
Hedysarum canadensis L.
Meibomia canadensis (L.) Kuntze Revis. Gen. Pl.1: 195 (1891)
Hedysarum canadense L. Sp. Pl.: 748 (1753)
Edusaron canadense (L.) Medik. Vorles. Churpfälz. Phys.-Ökon. Ges.2: 371 (1787)
Hedysarum scabrum Moench Methodus: 118 (1794)
Pleurolobus canadensis MacMill. Metasp. Minnesota Valley: 319 (1892)
Desmodium canadense var. minus Hook. Fl. Bor.-Amer.1: 154 (1834)

Common names Top

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Language Common/alternative name
English canada tick-clover
English canada tick-trefoil
English canada tickclover
English canadian tick-trefoil
English showy tick trefoil
English showy tick-trefoil
English showy ticktrefoil
French desmodie du canada
Swedish lusväppling
Chinese 美洲山蚂蝗

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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No forms added yet.

Germination/Propagation Top

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Sow seeds at 20°C, expecting germination within 3 months without further temperature treatment.
Requires Scarification: Scarification involves physically breaking, scratching, or softening the seed coat to allow water absorption and germination to occur. This can be done by nicking the seed coat with a knife or rubbing the seeds between sheets of sandpaper.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Northern America
    • Eastern Canada
      • New Brunswick
      • Ontario
      • Québec
    • North-central U.S.A.
      • Illinois
      • Kansas
      • Minnesota
      • Nebraska
      • North Dakota
      • Oklahoma
      • South Dakota
      • Wisconsin
    • Northeastern U.S.A.
      • Indiana
      • Maine
      • Michigan
      • New Hampshire
      • New York
      • Ohio
      • Pennsylvania
      • Vermont
      • West Virginia
    • South-central U.S.A.
      • Texas
    • Southeastern U.S.A.
      • Maryland
      • Virginia

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000170488
Canadensys 5717
USDA Plants DECA7
Tropicos 13018345
KEW urn:lsid:ipni.org:names:1051889-2
The Plant List ild-16761
Open Tree Of Life 703608
NCBI Taxonomy 932098
Nature Serve 2.139796
IPNI 1051889-2
iNaturalist 129505
GBIF 2967285
Freebase /m/0gsrgx
WisFlora 3367
EPPO DEDCD
EOL 639746
USDA GRIN 13617
Wikipedia Desmodium_canadense
CMAUP NPO16182

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Biological Control and Habitat Management for the Control of Onion Thrips, Thrips tabaci Lindeman (Thysanoptera: Thripidae), in Onion Production in Quebec, Canada Gagnon AÈ, Fortier AM, Audette C Insects 27-Mar-2024
PMCID:PMC11050518
doi:10.3390/insects15040232
PMID:38667362
An Investigation of the Antiviral Potential of Phytocompounds against Avian Infectious Bronchitis Virus through Template-Based Molecular Docking and Molecular Dynamics Simulation Analysis Gul I, Hassan A, Haq E, Ahmad SM, Shah RA, Ganai NA, Chikan NA, Abdul-Careem MF, Shabir N Viruses 26-Mar-2023
PMCID:PMC10144825
doi:10.3390/v15040847
PMID:37112828
Synthesis of Novel 1,3,4-Oxadiazole-Derived α-Aminophosphonates/α-Aminophosphonic Acids and Evaluation of Their In Vitro Antiviral Activity against the Avian Coronavirus Infectious Bronchitis Virus Hkiri S, Mekni-Toujani M, Üstün E, Hosni K, Ghram A, Touil S, Samarat A, Sémeril D Pharmaceutics 29-Dec-2022
PMCID:PMC9867332
doi:10.3390/pharmaceutics15010114
PMID:36678743
A Mixed Model for Assessing the Effect of Numerous Plant Species Interactions on Grassland Biodiversity and Ecosystem Function Relationships McDonnell J, McKenna T, Yurkonis KA, Hennessy D, de Andrade Moral R, Brophy C J Agric Biol Environ Stat 01-Sep-2022
PMCID:PMC9908731
doi:10.1007/s13253-022-00505-2
PMID:36779040
Effects of Commercial Arbuscular Mycorrhizal Inoculants on Plant Productivity and Intra-Radical Colonization in Native Grassland: Unintentional De-Coupling of a Symbiosis? Duell EB, Cobb AB, Wilson GW Plants (Basel) 31-Aug-2022
PMCID:PMC9460666
doi:10.3390/plants11172276
PMID:36079657
Novel and Alternative Therapeutic Strategies for Controlling Avian Viral Infectious Diseases: Focus on Infectious Bronchitis and Avian Influenza Abbas G, Yu J, Li G Front Vet Sci 22-Jul-2022
PMCID:PMC9353128
doi:10.3389/fvets.2022.933274
PMID:35937298
Reinventory of the vascular plants of Mormon Island Crane Meadows after forty years of restoration, invasion, and climate change Caven AJ, Wiese JD Heliyon 03-Jun-2022
PMCID:PMC9192816
doi:10.1016/j.heliyon.2022.e09640
PMID:35711997
Effect of herbal compounds on coronavirus; a systematic review and meta-analysis Kesheh MM, Shavandi S, Haeri Moghaddam N, Ramezani M, Ramezani F Virol J 21-May-2022
PMCID:PMC9123756
doi:10.1186/s12985-022-01808-z
PMID:35597998
In vivo antiviral effect of plant essential oils against avian infectious bronchitis virus Zhang Y, Li XY, Zhang BS, Ren LN, Lu YP, Tang JW, Lv D, Yong L, Lin LT, Lin ZX, Mo Q, Mo ML BMC Vet Res 07-Mar-2022
PMCID:PMC8899001
doi:10.1186/s12917-022-03183-x
PMID:35255906
Can Artemisia herba-alba Be Useful for Managing COVID-19 and Comorbidities? Hasan A, Biswas P, Bondhon TA, Jannat K, Paul TK, Paul AK, Jahan R, Nissapatorn V, Mahboob T, Wilairatana P, Hasan MN, de Lourdes Pereira M, Wiart C, Rahmatullah M Molecules 13-Jan-2022
PMCID:PMC8779608
doi:10.3390/molecules27020492
PMID:35056809
Licorice (Glycyrrhiza glabra) Extracts-Suitable Pharmacological Interventions for COVID-19? A Review Abraham J, Florentine S Plants (Basel) 26-Nov-2021
PMCID:PMC8708549
doi:10.3390/plants10122600
PMID:34961070
A Brief Overview of Potential Treatments for Viral Diseases Using Natural Plant Compounds: The Case of SARS-Cov Abiri R, Abdul-Hamid H, Sytar O, Abiri R, Bezerra de Almeida E Jr, Sharma SK, Bulgakov VP, Arroo RR, Malik S Molecules 24-Jun-2021
PMCID:PMC8270261
doi:10.3390/molecules26133868
PMID:34202844
Bradyrhizobium septentrionale sp. nov. (sv. septentrionale) and Bradyrhizobium quebecense sp. nov. (sv. septentrionale) associated with legumes native to Canada possess rearranged symbiosis genes and numerous insertion sequences Bromfield ES, Cloutier S Int J Syst Evol Microbiol 09-Jun-2021
PMCID:PMC8374602
doi:10.1099/ijsem.0.004831
PMID:34106824
Anti–SARS-CoV-2 Natural Products as Potentially Therapeutic Agents Kim CH Front Pharmacol 27-May-2021
PMCID:PMC8194829
doi:10.3389/fphar.2021.590509
PMID:34122058
A review of Cameroonian medicinal plants with potentials for the management of the COVID-19 pandemic Fongnzossie Fedoung E, Biwole AB, Nyangono Biyegue CF, Ngansop Tounkam M, Akono Ntonga P, Nguiamba VP, Essono DM, Forbi Funwi P, Tonga C, Nguenang GM, Kemeuze V, Sonwa DJ, Tsabang N, Bouelet IS, Tize Z, Boum AT, Momo Solefack MC, Betti JL, Nouga Bissoue A, Lehman LG, Mapongmetsem PM, Nneme Nneme L, Ngono Ngane RA, Ngogang Yonkeu J 26-Mar-2021
PMCID:PMC7994110
doi:10.1007/s13596-021-00567-6

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
Lupeol 259846 Click to see CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)C 426.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
Sitogluside 5742590 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C 576.80 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavones
5,7-dihydroxy-2-[4-hydroxy-2-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]chromen-4-one 162911690 Click to see 432.40 unknown https://doi.org/10.1007/BF00563474
5,7-Dihydroxy-2-[4-hydroxy-2-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]chromen-4-one 162911689 Click to see 432.40 unknown https://doi.org/10.1007/BF00563474
5,7-dihydroxy-2-[4-hydroxy-3-[(2R,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]chromen-4-one 162929829 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)C4C(C(C(C(O4)CO)O)O)O)O 432.40 unknown https://doi.org/10.1007/BF00563474
5,7-Dihydroxy-2-[4-hydroxy-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]chromen-4-one 162929828 Click to see 432.40 unknown https://doi.org/10.1007/BF00563474
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid C-glycosides
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-6-(3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)chromen-4-one 6426860 Click to see 448.40 unknown https://doi.org/10.1007/BF00563474
5,7-Dihydroxy-2-(4-Hydroxyphenyl)-6-(3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl)Chromen-4-One 4475102 Click to see 432.40 unknown https://doi.org/10.1007/BF00563474
5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2R,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one 57511421 Click to see 432.40 unknown https://doi.org/10.1007/BF00563474
Isoorientin 114776 Click to see 448.40 unknown https://doi.org/10.1007/BF00563474
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid C-glycosides / Flavonoid 8-C-glycosides
5,7-dihydroxy-2-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one 5378180 Click to see C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4C(C(C(C(O4)CO)O)O)O)O 432.40 unknown https://doi.org/10.1007/BF00563474
Homo-orientin 5382105 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4C(C(C(C(O4)CO)O)O)O)O)O 448.40 unknown https://doi.org/10.1007/BF00563474
https://doi.org/10.1007/BF00565808
Orientin 5281675 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4C(C(C(C(O4)CO)O)O)O)O)O 448.40 unknown https://doi.org/10.1007/BF00563474
Vitexin 5280441 Click to see 432.40 unknown https://doi.org/10.1007/BF00563474
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
Isorhamnetin 3-O-glucoside 5318645 Click to see 478.40 unknown via CMAUP database
Kaempferol-3-O-Rutinoside 5318767 Click to see 594.50 unknown via CMAUP database
Rutin 5280805 Click to see 610.50 unknown https://doi.org/10.1007/BF00565808
Trifolin 5282149 Click to see C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O 448.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides
Boldoside 72188972 Click to see 624.50 unknown via CMAUP database
Robinin 5281693 Click to see 740.70 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids
(2R)-5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one 14057197 Click to see 300.30 unknown via CMAUP database
> Phenylpropanoids and polyketides / Isoflavonoids / Furanoisoflavonoids / Pterocarpans
Melilitocarpan B 23259931 Click to see 286.28 unknown via CMAUP database
> Phenylpropanoids and polyketides / Isoflavonoids / O-methylated isoflavonoids / 4-O-methylated isoflavonoids / 3-hydroxy,4-methoxyisoflavonoids
(R)-Mucronulatol 13873811 Click to see 302.32 unknown via CMAUP database
Calycosin 5280448 Click to see 284.26 unknown via CMAUP database
> Phenylpropanoids and polyketides / Isoflavonoids / O-methylated isoflavonoids / 4-O-methylated isoflavonoids / 4-O-methylisoflavones
2'-Hydroxybiochanin A 5282075 Click to see 300.26 unknown via CMAUP database
Biochanin A 5280373 Click to see 284.26 unknown via CMAUP database
> Phenylpropanoids and polyketides / Isoflavonoids / O-methylated isoflavonoids / 7-O-methylated isoflavonoids / 7-O-methylisoflavones
4',7-Dimethoxyisoflavone 136419 Click to see 282.29 unknown via CMAUP database
> Phenylpropanoids and polyketides / Linear 1,3-diarylpropanoids / Chalcones and dihydrochalcones / 2-Hydroxychalcones
1-(2,4-Dihydroxyphenyl)-3-(2,3-dimethoxyphenyl)prop-2-en-1-one 622927 Click to see 300.30 unknown via CMAUP database
1-(2,4-Dihydroxyphenyl)-3-(4-Hydroxyphenyl)Prop-2-En-1-One 425 Click to see 256.25 unknown via CMAUP database
2',4'-Dihydroxy-4-methoxychalcone 5711223 Click to see COC1=CC=C(C=C1)C=CC(=O)C2=C(C=C(C=C2)O)O 270.28 unknown via CMAUP database
2a(2),4a(2)-Dihydroxy-3,4-dimethoxychalcone 165210 Click to see COC1=C(C=C(C=C1)C=CC(=O)C2=C(C=C(C=C2)O)O)OC 300.30 unknown via CMAUP database
> Phenylpropanoids and polyketides / Linear 1,3-diarylpropanoids / Chalcones and dihydrochalcones / 3-prenylated chalcones
2',4',4-Trihydroxy-3'-prenylchalcone 193568 Click to see 324.40 unknown via CMAUP database

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