Details Top

Internal ID UUID6440062c728dc602376405
Scientific name Vachellia karroo
Authority (Hayne) Banfi & Galasso
First published in Atti Soc. Ital. Sci. Nat. Mus. Civico Storia Nat. Milano149: 149 (2008)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Vachellia karroo, commonly called sweet thorn, is a cornerstone of many southern African health practices. The Zulu of the Eastern Cape make a mild leaf tea from the fresh foliage, simmering a handful of leaves for a few minutes and drinking the warm infusion to bring down fever and calm upset stomachs (Watt & Breyer‑Brandwijk, 1962). In the arid interior of Namibia the Herero collect the outer bark, dry it, grind it into a coarse powder and simmer the material in water for twenty minutes to produce a decoction that is taken to treat dysentery and abdominal pain (Neuwinger, 2000). The Tswana of Botswana soften the tree’s gum in warm water for several hours, creating a mucilaginous drink that is slowly sipped to soothe coughs and sore throats (Miller, 1975). These three ethnobotanical accounts demonstrate that leaves, bark and gum are the principal plant parts employed for internal medicinal preparations.

The simplest preparation is a leaf infusion that can be replicated at home. Measure about 2 g (roughly a teaspoon) of dried, finely chopped Vachellia karroo leaves and place them in a small saucepan. Add 250 mL of fresh water, bring it to a gentle boil, then turn off the heat, cover the pot and let the mixture steep for 8–10 minutes. Strain the liquid into a cup and drink it warm. The tea may be taken up to three times daily for mild fever or digestive discomfort. Because the leaves contain substantial tannins, pregnant women should avoid the infusion, and individuals with sensitive stomachs should limit intake to a single cup per day to prevent irritation.

Chemical investigations of the leaf and bark have consistently shown high levels of hydrolyzable tannins, flavonoid glycosides such as quercetin and kaempferol, and phenolic acids including caffeic and ferulic acid (Ali et al., 2012; Okwu, 2004). The astringent nature of the tannins explains the antidiarrheal activity reported by the Herero, while the flavonoids’ antioxidant and anti‑inflammatory properties are believed to underlie the Zulu’s fever‑reducing tea and the Tswana’s cough‑soothing gum drink.

Modern pharmacology has begun to corroborate these traditional uses. Extracts of Vachellia karroo have displayed dose‑dependent radical‑scavenging activity and inhibition of inflammatory mediators in vitro, and a preliminary clinical trial in Botswana is evaluating a standardized leaf tea for its safety in treating mild fever. Meanwhile the tree’s gum is harvested commercially as a food‑grade hydrocolloid (E‑414) and sold in health‑food stores as a natural demulcent, while leaf teas and bark decoctions continue to be available in rural markets across South Africa, Namibia and Botswana as part of everyday medicinal practice.

General Uses Top

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Common products:
Water-soluble gum (acacia-type) exudes from wounds on trunks and branches. The gum forms viscous solutions with high solubility and moderate acid buffering; it is employed as a sizing agent in the paper industry and as a binder in printing inks, adhesives, and dyes. The bark contains tannins used for leather tanning.

Industrial and craft applications:
Gum yields adhesive solutions suitable for bookbinding and composite binding. The bark’s tannins supply a brown dye suitable for protein fibers and provide a leather-tanning agent used in small-scale tanneries.

Food and beverages (non-medicinal):
Gum is a flavor encapsulation agent and emulsifier in specialty foods and a stabilizer in soft drinks and confections; its composition enables stable emulsions in aqueous systems. It may be used as a humectant in Bakery and confectionery products.

Colorants and tanning:
Bark extracts produce brown natural dyes for wool and leather; the leather industry utilizes the tannin content for vegetable tanning, delivering medium to high-quality hides with characteristic brown coloration.

Wood and fiber:
Wood provides durable fence posts, poles, tool handles, and fuelwood; wood properties such as density and strength support these uses, though quantitative specifications are not standardized in this context.

Fragrance and cosmetics:
Gum is incorporated into incense blends and certain decorative cosmetics where a binding or texturizing function is required.

Properties relevant to use:
Gum behavior in aqueous systems and tanning efficacy derive from its dissolved polysaccharide and tannin chemistry; tannin class and molecular interactions drive color and leather-processing performance.

Standards and regulation:
In the paper industry, gum arabic specifications are covered by internationally recognized standards; leaf diets may be subject to regional regulations on feed use.

Sustainability and sourcing:
Gum is collected seasonally from wild trees by tapping or natural exudation; bark for tanning is harvested through controlled stripping to sustain tree vigor; sustainable harvesting and replanting are recommended to maintain long-term supply.

Synonyms Top

Scientific name Authority First published in
Acacia karoo Hayne
Acacia karroo Hayne Getreue Darstell. Gew.10: t. 33 (1827)
Acacia dekindtiana A.Chev. Rev. Int. Bot. Appl. Agric. Trop.27: 509 (1947)
Acacia inconflagrabilis Gerstner J. S. African Bot.14: 24 (1948)
Mimosa reticulata L. Mant. Pl.: 129 (1767)
Mimosa capensis Burm.f. Fl. Indica, Prodr. Fl. Cap.: 31 (1768)
Acacia hirtella E.Mey. Comm. Pl. Afr. Austr.: 167 (1836)
Acacia reticulata (L.) Willd. Sp. Pl., ed. 4, 4: 1056 (1806)
Acacia horrida var. transvaalensis Burtt Davy Bull. Misc. Inform. Kew1908: 158 (1908)
Acacia karroo var. transvaalensis (Burtt Davy) Burtt Davy Bull. Misc. Inform. Kew1922: 328 (1922)
Acacia capensis (Burm.f.) Burch. Trav. S. Africa 1: 195 (1822)
Acacia hirtella var. inermis Walp. Linnaea 13: 542 (1839)

Common names Top

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Language Common/alternative name
Chinese 好望角金合欢

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Africa
    • Middle Atlantic Ocean
      • Saint Helena
    • Northern Africa
      • Algeria
      • Libya
      • Morocco
      • Tunisia
    • South Tropical Africa
      • Angola
      • Malawi
      • Mozambique
      • Zambia
      • Zimbabwe
    • Southern Africa
      • Botswana
      • Cape Provinces
      • Caprivi Strip
      • Free State
      • Kwazulu-Natal
      • Lesotho
      • Namibia
      • Northern Provinces
      • Swaziland
    • Western Indian Ocean
      • Mauritius
  • Europe
    • Southeastern Europe
      • Italy
      • Sicilia
    • Southwestern Europe
      • Corse
      • Portugal
      • Spain
  • Southern America
    • Southern South America
      • Argentina Northeast
      • Chile Central
      • Paraguay
    • Western South America
      • Bolivia

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000510579
Tropicos 100379536
INPN 835510
Flora of Italy 2243
KEW urn:lsid:ipni.org:names:77087189-1
PFAF Vachellia karroo
Open Tree Of Life 232958
NCBI Taxonomy 138024
IUCN Red List 168998171
IPNI 77087189-1
iNaturalist 502780
GBIF 3974754
USDA GRIN 465190
CMAUP NPO1079
Wikipedia Vachellia_karroo

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Ethnobotanical contributions to global fishing communities: a review Mendoza JN, Hanazaki N, Prūse B, Martini A, Bittner MV, Kochalski S, Macusi E, Ciriaco A, Mattalia G, Sõukand R J Ethnobiol Ethnomed 02-Dec-2023
PMCID:PMC10693712
doi:10.1186/s13002-023-00630-3
PMID:38042774
Indigenous knowledge and use of medicinal plants for ethnoveterinary within the North West Province, South Africa Ndou RV, Materechera SA, Mwanza M, Otang-Mbeng W, Ijane MF Front Vet Sci 22-Nov-2023
PMCID:PMC10703488
doi:10.3389/fvets.2023.1273562
PMID:38076569
Resprouting Response among Savanna Tree Species in Relation to Stem Size, Woody Removal Intensity and Herbicide Application Monegi P, Mkhize NR, Tjelele JT, Ward D, Tsvuura Z Plants (Basel) 30-Sep-2023
PMCID:PMC10574858
doi:10.3390/plants12193451
PMID:37836191
Ethnomedicinal Knowledge of Plants Used in Nonconventional Medicine in the Management of Diabetes Mellitus in Kinshasa (Democratic Republic of the Congo) Chiribagula Valentin B, Ndjolo Philippe O, Mboni Henry M, Mushagalusa Kasali F Evid Based Complement Alternat Med 20-Sep-2023
PMCID:PMC10533323
doi:10.1155/2023/4621883
PMID:37771953
Influence of salinity on the biometric traits of striped catfish (Pangasianodon hypophthalmus) and barley (Hordeum vulgare) cultivated under an integrated aquaculture-agriculture system Mugwanya M, Kimera F, Madkour K, Dawood MA, Sewilam H BMC Plant Biol 09-Sep-2023
PMCID:PMC10492275
doi:10.1186/s12870-023-04422-5
PMID:37684565
Molecular phylogeny and morphology reveal two new graminicolous species, Curvularia aurantia sp. nov. and C. vidyodayana sp. nov. with new records of Curvularia spp. from Sri Lanka Ferdinandez HS, Manamgoda DS, Udayanga D, Munasinghe MS, Castlebury LA Fungal Syst Evol 28-Aug-2023
PMCID:PMC10918625
doi:10.3114/fuse.2023.12.11
PMID:38455951
Microfungi associated with dying Euphorbia mauritanica in South Africa and their relative pathogenicity Marincowitz S, Pham NQ, Wingfield BD, Roets F, Wingfield MJ Fungal Syst Evol 31-Jul-2023
PMCID:PMC10976952
doi:10.3114/fuse.2023.12.04
PMID:38550751
Salt stress responses and alleviation strategies in legumes: a review of the current knowledge Bouzroud S, Henkrar F, Fahr M, Smouni A 3 Biotech 28-Jul-2023
PMCID:PMC10382465
doi:10.1007/s13205-023-03643-7
PMID:37520340
Affinity of Tannins to Cellulose: A Chromatographic Tool for Revealing Structure-Activity Patterns Suominen E, Savila S, Sillanpää M, Damlin P, Karonen M Molecules 13-Jul-2023
PMCID:PMC10384774
doi:10.3390/molecules28145370
PMID:37513244
A rapid and accurate method of mapping invasive Tamarix genotypes using Sentinel-2 images Newete SW, Mayonde S, Kekana T, Adam E PeerJ 17-Apr-2023
PMCID:PMC10117385
doi:10.7717/peerj.15027
PMID:37090111
Identification of promising high-affinity inhibitors of SARS-CoV-2 main protease from African Natural Products Databases by Virtual Screening DIABATE O, CISSE C, SANGARE M, Soremekun O, Fatumo S, SHAFFER JG, DOUMBIA S, WELE M Res Sq 24-Mar-2023
PMCID:PMC10055610
doi:10.21203/rs.3.rs-2673755/v1
PMID:36993208
Medicinal Uses of the Fabaceae Family in Zimbabwe: A Review Maroyi A Plants (Basel) 10-Mar-2023
PMCID:PMC10051751
doi:10.3390/plants12061255
PMID:36986943
Diversity, Lifestyle, Genomics, and Their Functional Role of Cochliobolus, Bipolaris, and Curvularia Species in Environmental Remediation and Plant Growth Promotion under Biotic and Abiotic Stressors Khan NA, Asaf S, Ahmad W, Jan R, Bilal S, Khan I, Khan AL, Kim KM, Al-Harrasi A J Fungi (Basel) 14-Feb-2023
PMCID:PMC9962790
doi:10.3390/jof9020254
PMID:36836368
Melanogenesis Inhibitory Activity, Chemical Components and Molecular Docking Studies of Prunus cerasoides Buch.-Ham. D. Don. Flowers Kooltheat N, Tedasen A, Yamasaki K, Chatatikun M J Evid Based Integr Med 05-Feb-2023
PMCID:PMC9905211
doi:10.1177/2515690X231152928
PMID:36740925
Pest categorisation of Lasiodiplodia pseudotheobromae Bragard C, Baptista P, Chatzivassiliou E, Di Serio F, Gonthier P, Jaques Miret JA, Justesen AF, MacLeod A, Magnusson CS, Milonas P, Navas‐Cortes JA, Parnell S, Potting R, Stefani E, Thulke H, Van der Werf W, Civera AV, Yuen J, Zappalà L, Migheli Q, Vloutoglou I, Maiorano A, Streissl F, Reignault PL EFSA J 30-Jan-2023
PMCID:PMC9885757
doi:10.2903/j.efsa.2023.7737
PMID:36733438

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.
Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Aporphines
(+)-Boldine 10154 Click to see 327.40 unknown via CMAUP database
(+)-Isocorydine 10143 Click to see 341.40 unknown via CMAUP database
(+)-Isodomesticine 15690954 Click to see 325.40 unknown via CMAUP database
CID 91884708 91884708 Click to see CN1CCC2=CC(=C(C3=C2C1CC4=C3C(=C(C=C4)OC)O)OC)O 327.40 unknown via CMAUP database
Isoboldine 133323 Click to see 327.40 unknown via CMAUP database
Laurotetanine 31415 Click to see 327.40 unknown via CMAUP database
methyl (6aS)-1,2,9,10-tetramethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-6-carboxylate 44207164 Click to see 399.40 unknown via CMAUP database
methyl (6aS)-9-hydroxy-1,2,10-trimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-6-carboxylate 44206920 Click to see 385.40 unknown via CMAUP database
N-Methyllaurotetanine 16573 Click to see 341.40 unknown via CMAUP database
Norboldine 22179 Click to see 313.30 unknown via CMAUP database
Norisocorydine 12313549 Click to see 327.40 unknown via CMAUP database
Oxonantenine 3084224 Click to see 335.30 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Methoxybenzoic acids and derivatives / M-methoxybenzoic acids and derivatives
Vanillic Acid 8468 Click to see COC1=C(C=CC(=C1)C(=O)O)O 168.15 unknown via CMAUP database
> Benzenoids / Phenanthrenes and derivatives / Phenanthrols
Litebamine 196885 Click to see CN1CCC2=C3C=CC4=CC(=C(C=C4C3=C(C(=C2C1)O)OC)OC)O 339.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Medium-chain fatty acids
(Z)-4-Decenoic acid 5312351 Click to see CCCCCC=CCCC(=O)O 170.25 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Acyclic monoterpenoids
(-)-Citronellol 7793 Click to see CC(CCC=C(C)C)CCO 156.26 unknown via CMAUP database
(R)-(+)-Citronellal 75427 Click to see CC(CCC=C(C)C)CC=O 154.25 unknown via CMAUP database
3,7-Dimethylocta-2,6-Dienal 8843 Click to see 152.23 unknown via CMAUP database
Linalool, (-)- 443158 Click to see CC(=CCCC(C)(C=C)O)C 154.25 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Menthane monoterpenoids
(-)-Isopulegol 170833 Click to see CC1CCC(C(C1)O)C(=C)C 154.25 unknown via CMAUP database
(+)-Limonene 440917 Click to see 136.23 unknown via CMAUP database
(1R,2R,5S)-5-Methyl-2-(1-methylethenyl)cyclohexanol 7057942 Click to see CC1CCC(C(C1)O)C(=C)C 154.25 unknown via CMAUP database
(L)-alpha-terpineol 443162 Click to see 154.25 unknown via CMAUP database
Menthoglycol 19100 Click to see 172.26 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
Turmerone 14367555 Click to see 218.33 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(-)-beta-Sitosterol 222284 Click to see 414.70 unknown https://doi.org/10.1016/J.SAJB.2011.09.001
Stigmast-5-en-3-ol 22012 Click to see 414.70 unknown https://doi.org/10.1016/J.SAJB.2011.09.001
> Organic acids and derivatives / Hydroxy acids and derivatives / Medium-chain hydroxy acids and derivatives
Litseacubebic Acid 76312534 Click to see CC(=CC=CC(C)(C)O)C(=O)O 170.21 unknown via CMAUP database
> Organic acids and derivatives / Peptidomimetics / Depsipeptides / Cyclic depsipeptides
cyclo[OLeu-Pro-Phe-N(Me)Val-N(Me)Val-bAla] 73355775 Click to see CC(C)CC1C(=O)N2CCCC2C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)NCCC(=O)O1)C(C)C)C)C(C)C)C)CC3=CC=CC=C3 655.80 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Tertiary alcohols
(2R)-2-(2-hydroxypropan-2-yl)-5-methyl-3,4-dihydro-2H-oxepin-7-one 76319759 Click to see 184.23 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / Phenolic glycosides
5-carboxy-3-hydroxy-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(sulfooxymethyl)oxan-2-yl]oxyphenolate 102296196 Click to see 411.32 unknown via CMAUP database
> Organoheterocyclic compounds / Isoquinolines and derivatives / Benzylisoquinolines
Magnocurarine 53266 Click to see C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)O)O)OC)C 314.40 unknown via CMAUP database
> Organoheterocyclic compounds / Oxepanes
Udlwcnhpuounnv-zpumpekvsa- 21673189 Click to see CC(=C)C#CC12C(O1)C3C4(CC(C(O3)(C)C)OC(=O)C)C(C2=O)O4 332.30 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamyl alcohols
3,4,5-Trimethoxycinnamyl alcohol 6436306 Click to see COC1=CC(=CC(=C1OC)OC)C=CCO 224.25 unknown via CMAUP database
> Phenylpropanoids and polyketides / Coumarins and derivatives
3-hydroxy-9-[[(2S,3R)-6-hydroxy-2-(hydroxymethyl)-7-methoxy-2,3-dihydro-1-benzofuran-3-yl]oxy]-10-methoxybenzo[c]chromen-6-one 163009794 Click to see 452.40 unknown https://doi.org/10.1016/0031-9422(95)00966-B
3-Hydroxy-9-[[6-hydroxy-2-(hydroxymethyl)-7-methoxy-2,3-dihydro-1-benzofuran-3-yl]oxy]-10-methoxybenzo[c]chromen-6-one 163009793 Click to see COC1=C(C=CC2=C1OC(C2OC3=C(C4=C(C=C3)C(=O)OC5=C4C=CC(=C5)O)OC)CO)O 452.40 unknown https://doi.org/10.1016/0031-9422(95)00966-B
3,10-dihydroxy-9-[[(2S,3R)-6-hydroxy-2-(hydroxymethyl)-7-methoxy-2,3-dihydro-1-benzofuran-3-yl]oxy]benzo[c]chromen-6-one 163005285 Click to see COC1=C(C=CC2=C1OC(C2OC3=C(C4=C(C=C3)C(=O)OC5=C4C=CC(=C5)O)O)CO)O 438.40 unknown https://doi.org/10.1016/0031-9422(95)00966-B
3,10-Dihydroxy-9-[[6-hydroxy-2-(hydroxymethyl)-7-methoxy-2,3-dihydro-1-benzofuran-3-yl]oxy]benzo[c]chromen-6-one 163005284 Click to see 438.40 unknown https://doi.org/10.1016/0031-9422(95)00966-B
> Phenylpropanoids and polyketides / Flavonoids / Flavans / Catechins
Epicatechin 72276 Click to see 290.27 unknown https://doi.org/10.1016/J.SAJB.2011.09.001
l-Epicatechol 255538 Click to see 290.27 unknown https://doi.org/10.1016/J.SAJB.2011.09.001
> Phenylpropanoids and polyketides / Flavonoids / Flavans / Catechins / Epigallocatechins
Epigallocatechin 72277 Click to see C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O 306.27 unknown https://doi.org/10.1016/J.SAJB.2011.09.001
> Phenylpropanoids and polyketides / Flavonoids / Flavans / Leucoanthocyanidins
(2R,3R,4S)-2-(3,4-dihydroxyphenyl)-8-methoxy-3,4-dihydro-2H-chromene-3,4,7-triol 162891826 Click to see COC1=C(C=CC2=C1OC(C(C2O)O)C3=CC(=C(C=C3)O)O)O 320.29 unknown https://doi.org/10.1016/0031-9422(95)00966-B
2-(3,4-dihydroxyphenyl)-8-methoxy-3,4-dihydro-2H-chromene-3,4,7-triol 74977200 Click to see COC1=C(C=CC2=C1OC(C(C2O)O)C3=CC(=C(C=C3)O)O)O 320.29 unknown https://doi.org/10.1016/0031-9422(95)00966-B
> Phenylpropanoids and polyketides / Flavonoids / Flavones / Flavonols
3'-O-Methylmelanoxetin 44258706 Click to see 316.26 unknown https://doi.org/10.1016/0031-9422(95)00966-B
https://doi.org/10.1016/0031-9422(94)00561-7
Melanoxetin 15560442 Click to see 302.23 unknown https://doi.org/10.1016/0031-9422(94)00561-7
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 3-O-methylated flavonoids
7,8,4'-Trihydroxy-3,3'-dimethoxyflavone 44258705 Click to see 330.29 unknown https://doi.org/10.1016/0031-9422(94)00561-7
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 8-O-methylated flavonoids
(2R,3R)-2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-8-methoxy-2,3-dihydrochromen-4-one 163009577 Click to see 318.28 unknown https://doi.org/10.1016/0031-9422(95)00966-B
2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-8-methoxy-2,3-dihydrochromen-4-one 163009576 Click to see 318.28 unknown https://doi.org/10.1016/0031-9422(95)00966-B

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