Arnebia hispidissima

Details Top

Internal ID UUID64400ace09b9d142101380
Scientific name Arnebia hispidissima
Authority (Lehm.) A.DC.
First published in Prodr. 10: 94 1846

Ethnobotanical Use Top

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General Uses Top

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Common products:
- Root extract, dried root powder, and concentrated pigment preparation containing naphthoquinone compounds (alkannin, shikonin derivatives).

Industrial and craft applications:
- Natural red dye for textile fibers (silk, wool, cotton) used with mordant systems (e.g., aluminum or iron) to produce shades ranging from scarlet to deep maroon.
- Ink production for artistic use; the pigment provides a permanent red hue on paper and canvas.
- Leather coloration; the dye imparts a reddish tint to finished leather goods (used as a colorant, not as a tanning agent).

Colorants and tanning:
- The plant’s roots supply a natural red colorant suitable for protein fibers and leather; it is employed as a dye rather than a tannin.
- Colorfastness after mordanting meets standard textile testing (ISO 105‑C06).

Fragrance and cosmetics:
- Extracts rich in alkannin/shikonin are incorporated as red pigments in cosmetics (lipsticks, nail enamels, skin‑care creams) and listed under INCI nomenclature.
- The root oil contributes minor fragrance notes used in natural perfumery.

Properties relevant to use:
- Naphthoquinone content of approximately 0.5–2 % w/w of dry root yields high color intensity.
- Pigments are soluble in ethanol and oils, facilitating formulation in dye baths, inks, and cosmetic emulsions.
- Lightfastness and oxidative stability are improved after complexation with metal mordants.

Standards and regulation:
- Cosmetic colorants derived from A. hispidissima must comply with the EU Cosmetic Regulation (EC) No 1223/2009, requiring safety assessment and inclusion on product labels.
- Textile dyes must meet ISO 105‑C06 for colorfastness to washing; the dye has been reported to satisfy these criteria.
- The species has not been authorized as a food additive (no E‑number) in the EU or United States as of 2025.

Sustainability and sourcing:
- Primary harvest occurs from wild populations in northern India; demand for the pigment has led to localized over‑harvesting.
- Cultivation by seed propagation is feasible and recommended to reduce pressure on wild stocks.
- Sustainable‑harvest guidelines suggest limiting annual collection to ≤10 % of the standing population and promoting habitat protection.

Synonyms Top

Scientific name Authority First published in
Lithospermum villosum G.Don ex A.DC. Prodr. 10: 86 1846
Lithospermum villosum Wall. & G.Don Gen. Hist. 4: 325 (1837)
Rhytispermum villosum Link Handbuch 1: 580 (1829)
Toxostigma luteum A.Rich. Tent. Fl. Abyss. 2: 86 (1850)
Strobila hispidissima G.Don Gen. Hist. 4: 327 (1837)
Anchusa asperrima Delile Descr. Egypte, Hist. Nat. : 55 (1813)
Anchusa hispidissima Sieber ex DC. Prodr. [A. P. de Candolle] 10: 94. 1846 [8 Apr 1846]
Arnebia asperrima (Delile) Hutch. & Dalziel Fl. W. Trop. Afr. 2: 201 (1931)
Arnebia lutea (A.Rich.) Armari Annuario Reale Ist. Bot. Roma 8: 161 (1904)
Arnebiola migiurtina Chiov. Fl. Somala 1: 227 (1929)
Dioclea hispidissima Spreng. Syst. Veg., ed. 16 [Sprengel] 1: 556. 1824 [dated 1825; publ. in late 1824]
Echiochilon hispidissimum Tausch Flora 12: 643 (1829)
Echioides asperrimum (Delile) Rothm. Repert. Spec. Nov. Regni Veg. 49: 56 (1940)
Lithospermum hispidissimum Lehm. Icon. Descr. Nov. Stirp. : t. 39 (1823)
Lithospermum vestitum Wall. Numer. List [Wallich] n. 941. 1829
Echioides asperrima (Delile) Rothm. Repert. Spec. Nov. Regni Veg. 49: 56 (1940)

Common names Top

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Language Common/alternative name
English arabian primrose
English spiny bugloss
Hausa jinin mutum
Chinese 阿拉伯报春花
Chinese 阿拉伯報春花

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Africa
    • Northeast Tropical Africa
      • Chad
      • Djibouti
      • Eritrea
      • Ethiopia
      • Socotra
      • Somalia
      • Sudan
    • Northern Africa
      • Egypt
    • West Tropical Africa
      • Niger
      • Nigeria
    • West-central Tropical Africa
      • Cameroon
  • Asia-temperate
    • Arabian Peninsula
      • Gulf States
      • Oman
      • Saudi Arabia
      • Yemen
    • China
      • Tibet
    • Western Asia
      • Iran
      • Palestine
      • Sinai
  • Asia-tropical
    • Indian Subcontinent
      • India
      • Pakistan
      • West Himalaya

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000549486
Tropicos 4002686
INPN 610612
KEW urn:lsid:ipni.org:names:113464-1
The Plant List kew-2652995
Open Tree Of Life 6062066
NCBI Taxonomy 2571305
IPNI 113464-1
iNaturalist 489768
GBIF 4065217
EPPO ANBHI
USDA GRIN 467732

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Investigation of phytochemicals isolated from selected Saudi medicinal plants as natural inhibitors of SARS CoV-2 main protease: In vitro, molecular docking and simulation analysis Alharbi YT, Abdel-Mageed WM, Basudan OA, Mothana RA, Tabish Rehman M, ElGamal AA, Alqahtani AS, Fantoukh OI, AlAjmi MF Saudi Pharm J 08-Mar-2024
PMCID:PMC10973196
doi:10.1016/j.jsps.2024.102023
PMID:38550333
High-throughput sequencing reveals the structure and metabolic resilience of desert microbiome confronting climate change Mousa WK, Abu-Izneid T, Salah-Tantawy A Front Plant Sci 05-Mar-2024
PMCID:PMC10953687
doi:10.3389/fpls.2024.1294173
PMID:38510442
Effect of heat-clearing and dampness-eliminating Chinese medicine for high-risk cervical cancer papillomavirus infection: a systematic review and meta-analysis of randomized controlled trials Huang S, Qi Y, Chen S, He B, Chen X, Xu J Front Med (Lausanne) 24-Aug-2023
PMCID:PMC10484520
doi:10.3389/fmed.2023.1022030
PMID:37692777
A new strategy for osteoarthritis therapy: Inhibition of glycolysis Tan C, Li L, Han J, Xu K, Liu X Front Pharmacol 10-Nov-2022
PMCID:PMC9685317
doi:10.3389/fphar.2022.1057229
PMID:36438808
Pharmacological and analytical aspects of alkannin/shikonin and their derivatives: An update from 2008 to 2022 Kaur K, Sharma R, Singh A, Attri S, Arora S, Kaur S, Bedi N Chin Herb Med 20-Sep-2022
PMCID:PMC9669360
doi:10.1016/j.chmed.2022.08.001
PMID:36405061
Aerobiological monitoring in a desert type ecosystem: Two sampling stations of two cities (2017–2020) in Qatar Al-Nesf MA, Gharbi D, Mobayed HM, Mohammed Ali R, Tuffaha A, Dason BR, Adeli M, Sattar HA, Trigo MD PLoS One 13-Jul-2022
PMCID:PMC9278729
doi:10.1371/journal.pone.0270975
PMID:35830387
Review of Shikonin and Derivatives: Isolation, Chemistry, Biosynthesis, Pharmacology and Toxicology Yadav S, Sharma A, Nayik GA, Cooper R, Bhardwaj G, Sohal HS, Mutreja V, Kaur R, Areche FO, AlOudat M, Shaikh AM, Kovács B, Mohamed Ahmed AE Front Pharmacol 01-Jul-2022
PMCID:PMC9283906
doi:10.3389/fphar.2022.905755
PMID:35847041
Endophytism: A Multidimensional Approach to Plant–Prokaryotic Microbe Interaction Rani S, Kumar P, Dahiya P, Maheshwari R, Dang AS, Suneja P Front Microbiol 12-May-2022
PMCID:PMC9135327
doi:10.3389/fmicb.2022.861235
PMID:35633681
Floristic composition of Jandaf Mountain as biodiversity hotspot area in southwestern Saudi Arabia Al-Namazi AA, Algarni SM, Wan JS, Al Mosallam MS, Alotaibi F Saudi J Biol Sci 05-Mar-2022
PMCID:PMC9280213
doi:10.1016/j.sjbs.2022.03.003
PMID:35844416
In vitro strategies for the enhancement of secondary metabolite production in plants: a review Fazili MA, Bashir I, Ahmad M, Yaqoob U, Geelani SN Bull Natl Res Cent 19-Feb-2022
PMCID:PMC8857880
doi:10.1186/s42269-022-00717-z
PMID:35221660
Comparison of Herbal Medicines Used for Women’s Menstruation Diseases in Different Areas of the World Jiao M, Liu X, Ren Y, Wang Y, Cheng L, Liang Y, Li Y, Zhang T, Wang W, Mei Z Front Pharmacol 04-Feb-2022
PMCID:PMC8854496
doi:10.3389/fphar.2021.751207
PMID:35185533
Biotechnological Advances in Pharmacognosy and In Vitro Manipulation of Pterocarpus marsupium Roxb. Ahmad A, Ahmad N, Anis M, Faisal M, Alatar AA, Abdel-Salam EM, Meena RP, Sivanesan I Plants (Basel) 18-Jan-2022
PMCID:PMC8839240
doi:10.3390/plants11030247
PMID:35161227
Hairy CRISPR: Genome Editing in Plants Using Hairy Root Transformation Kiryushkin AS, Ilina EL, Guseva ED, Pawlowski K, Demchenko KN Plants (Basel) 24-Dec-2021
PMCID:PMC8747350
doi:10.3390/plants11010051
PMID:35009056
Grape Pomace Extracted Tannin for Green Synthesis of Silver Nanoparticles: Assessment of Their Antidiabetic, Antioxidant Potential and Antimicrobial Activity Saratale RG, Saratale GD, Ahn S, Shin HS Polymers (Basel) 13-Dec-2021
PMCID:PMC8703727
doi:10.3390/polym13244355
PMID:34960905
Biogenic nanosized gold particles: Physico-chemical characterization and its anticancer response against breast cancer Singh N, Das MK, Ansari A, Mohanta D, Rajamani P Biotechnol Rep (Amst) 27-Mar-2021
PMCID:PMC8099502
doi:10.1016/j.btre.2021.e00612
PMID:33996520

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Naphthalenes / Naphthoquinones
(+-)-Shikonin 5208 Click to see 288.29 unknown https://doi.org/10.1055/S-2001-16470
https://doi.org/10.1016/0031-9422(83)83069-6
[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] (3E)-5-methylhexa-3,5-dienoate 163195328 Click to see 396.40 unknown https://doi.org/10.1055/S-2001-16470
[(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] 5-methylhexa-3,5-dienoate 163193700 Click to see 396.40 unknown https://doi.org/10.1055/S-2001-16470
[(1S)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] 3-hydroxy-3-methylbutanoate 10178341 Click to see CC(=CCC(C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O)OC(=O)CC(C)(C)O)C 388.40 unknown https://doi.org/10.1016/0031-9422(83)83069-6
2-(1-n-Butanoyloxy-4-methyl-3-pentenyl)-5,8-dihydroxy-1,4-naphthoquinone 10247808 Click to see CCCC(=O)OC(CC=C(C)C)C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O 358.40 unknown https://doi.org/10.1055/S-2001-16470
2-[5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)-1,4-dioxo-3H-naphthalen-2-yl]acetic acid 56842723 Click to see 348.30 unknown https://doi.org/10.1016/0031-9422(83)83069-6
Acetylalkannin 9967285 Click to see 330.30 unknown https://doi.org/10.1016/0031-9422(83)83069-6
Acetylshikonin 32464 Click to see CC(=CCC(C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O)OC(=O)C)C 330.30 unknown https://doi.org/10.1016/0031-9422(83)83069-6
Alkannin 72521 Click to see 288.29 unknown https://doi.org/10.1016/0031-9422(83)83069-6
https://doi.org/10.1016/S0944-7113(00)80077-X
Alkannin-beta-hydroxyisovalerate 100203 Click to see 388.40 unknown https://doi.org/10.1016/0031-9422(83)83069-6
Arnebin I 32465 Click to see 370.40 unknown https://doi.org/10.1016/S0944-7113(00)80077-X
Butylshikonin 10089766 Click to see 358.40 unknown https://doi.org/10.1055/S-2001-16470
Deoxyshikonin 98914 Click to see CC(=CCCC1=CC(=O)C2=C(C=CC(=C2C1=O)O)O)C 272.29 unknown https://doi.org/10.1016/S0944-7113(00)80077-X
https://doi.org/10.1016/0031-9422(83)83069-6
Isovalerylalkannin 5318685 Click to see CC(C)CC(=O)OC(CC=C(C)C)C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O 372.40 unknown https://doi.org/10.1016/0031-9422(83)83069-6
Isovalerylshikonin 335426 Click to see 372.40 unknown https://doi.org/10.1016/0031-9422(83)83069-6
Shikonin 479503 Click to see 288.29 unknown https://doi.org/10.1055/S-2001-16470
> Lipids and lipid-like molecules / Fatty Acyls / Fatty alcohols
1-Tetracosanol 10472 Click to see 354.70 unknown https://doi.org/10.1016/0031-9422(83)83069-6
> Lipids and lipid-like molecules / Prenol lipids / Quinone and hydroquinone lipids / Prenylquinones / Ubiquinones
5-[(2E,6Z,7Z)-6-ethylidene-2-methylnona-2,7-dienyl]-2,3-dimethoxycyclohexa-2,5-diene-1,4-dione 5320195 Click to see CC=CC(=CC)CCC=C(C)CC1=CC(=O)C(=C(C1=O)OC)OC 330.40 unknown https://doi.org/10.1055/S-2001-16470
5-[5-(Furan-3-yl)-2-methylpent-2-enyl]-2,3-dimethoxycyclohexa-2,5-diene-1,4-dione 125243 Click to see CC(=CCCC1=COC=C1)CC2=CC(=O)C(=C(C2=O)OC)OC 316.30 unknown https://doi.org/10.1055/S-2001-16470
Arnebifuranone 6438590 Click to see 316.30 unknown https://doi.org/10.1055/S-2001-16470
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
Beta-Amyrin 73145 Click to see CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C)C 426.70 unknown https://doi.org/10.1076/PHBI.41.4.231.15667
Betulin 72326 Click to see CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)CO 442.70 unknown https://doi.org/10.1076/PHBI.41.4.231.15667
Lupeol 259846 Click to see CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)C 426.70 unknown https://doi.org/10.1076/PHBI.41.4.231.15667
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(-)-beta-Sitosterol 222284 Click to see 414.70 unknown https://doi.org/10.1016/0031-9422(83)83069-6
17-(5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 86821 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown https://doi.org/10.1016/0031-9422(83)83069-6
Stigmast-5-en-3-ol 22012 Click to see 414.70 unknown https://doi.org/10.1016/0031-9422(83)83069-6
> Organic oxygen compounds / Organooxygen compounds / Ethers / Alkyl aryl ethers
(4E,8E)-4,8-Dimethyl-2-oxabicyclo(9.3.1)pentadeca-1(15),4,8,11,13-pentaen-12-ol 5281558 Click to see 244.33 unknown https://doi.org/10.1016/S0944-7113(00)80077-X

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