Helichrysum petiolare - Unknown
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Internal ID UUID643fc8b26ba67599608967
Scientific name Helichrysum petiolare
Authority Hilliard & B.L.Burtt
First published in Notes Roy. Bot. Gard. Edinburgh 32(3): 357, nom. nov. (1973)

Description Top

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Helichrysum petiolare, also known as the licorice-plant or liquorice plant, is a flowering plant native to South Africa and naturalized in parts of Portugal and the United States. It is a trailing evergreen subshrub with furry grey-green leaves and small white flowers. It is cultivated for its foliage and as groundcover, and numerous cultivars have been developed. In Southern Africa, it is known as imphepho and is used in traditional medicine and rituals. The plant has anti-microbial, anti-oxidant, and anti-inflammatory properties and is used to treat various ailments such as coughs, fever, and wounds. In rituals, imphepho is burnt to invoke and placate ancestors and is believed to increase spiritual awareness and psychic abilities. It is protected by South African law for its use in traditional beliefs.

Synonyms Top

Scientific name Authority First published in
Helichrysum petiolatum D.Don Mem. Wern. Nat. Hist. Soc. 5: 550 (1824)
Gnaphalium petiolatum L. Sp. Pl. : 854 (1753)
Helichrysum petiolatum (L.) DC.

Common names Top

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Language Common/alternative name
English licorice-plant
Afrikaans kooigoed
Arabic خالدة معنقة
Czech smil řapíkatý
German lakritz-strohblume
Estonian lamav käokuld
Polish kocanki włochate
Chinese 伞花蜡菊
Chinese 具柄蜡菊

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Sow seeds at 20°C, expecting germination within 3 months without further temperature treatment.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Africa
    • Macaronesia
      • Canary Islands
      • Madeira
    • South Tropical Africa
      • Angola
      • Zambia
      • Zimbabwe
    • Southern Africa
      • Cape Provinces
  • Europe
    • Eastern Europe
      • Krym
      • Ukraine
    • Northern Europe
      • Great Britain
      • Ireland
    • Southwestern Europe
      • Corse
      • Portugal
      • Spain

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000024510
USDA Plants HEPE8
Tropicos 2719447
INPN 101093
KEW urn:lsid:ipni.org:names:213170-1
The Plant List gcc-123685
Missouri Botanical Garden 277536
Open Tree Of Life 574618
Observations.org 138386
NCBI Taxonomy 261796
NBN Atlas NBNSYS0500000311
IPNI 213170-1
iNaturalist 77361
GBIF 3131367
Freebase /m/0824wx
EPPO HECPE
EOL 590505
Calflora (Californian flora) 8487
USDA GRIN 404767
Wikipedia Helichrysum_petiolare

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
HPLC-based cytotoxicity profiling and LC-ESIQTOF-MS/MS analysis of Helichrysum leucocephalum Samimi-Dehkordi S, Tayarani-Najaran Z, Emami SA, Nesměrák K, Štícha M, Azizi N, Akaberi M Heliyon 28-Feb-2024
PMCID:PMC10915411
doi:10.1016/j.heliyon.2024.e27230
PMID:38449622
Topsoil and Vegetation Dynamics 14 Years after Eucalyptus grandis Removal in Eastern Cape Province of South Africa Mthethwa K, Ruwanza S Plants (Basel) 24-Aug-2023
PMCID:PMC10490425
doi:10.3390/plants12173047
PMID:37687294
Potential use of the Asteraceae family as a cure for diabetes: A review of ethnopharmacology to modern day drug and nutraceuticals developments Mohanta YK, Mishra AK, Nongbet A, Chakrabartty I, Mahanta S, Sarma B, Panda J, Panda SK Front Pharmacol 03-Aug-2023
PMCID:PMC10441548
doi:10.3389/fphar.2023.1153600
PMID:37608892
Chemical Study and Comparison of the Biological Activities of the Essential Oils of Helichrysum petiolare, H. cymosum, and H. odoratissimum Adewinogo SO, Sharma R, Africa CW, Marnewick JL, Hussein AA Plants (Basel) 03-Oct-2022
PMCID:PMC9573642
doi:10.3390/plants11192606
PMID:36235472
Ethnobotany and Toxicity Status of Medicinal Plants with Cosmeceutical Relevance from Eastern Cape, South Africa Ndhlala AR, Thibane VS, Masehla CM, Mokwala PW Plants (Basel) 30-May-2022
PMCID:PMC9182599
doi:10.3390/plants11111451
PMID:35684224
Helichrysum Genus and Compound Activities in the Management of Diabetes Mellitus Akinfenwa AO, Sagbo IJ, Makhaba M, Mabusela WT, Hussein AA Plants (Basel) 23-May-2022
PMCID:PMC9143910
doi:10.3390/plants11101386
PMID:35631811
Comparative Study of the Antioxidant Constituents, Activities and the GC-MS Quantification and Identification of Fatty Acids of Four Selected Helichrysum Species Akinyede KA, Hughes GD, Ekpo OE, Oguntibeju OO Plants (Basel) 07-Apr-2022
PMCID:PMC9028396
doi:10.3390/plants11080998
PMID:35448730
In Vitro Evaluation of the Anti-Diabetic Potential of Aqueous Acetone Helichrysum petiolare Extract (AAHPE) with Molecular Docking Relevance in Diabetes Mellitus Akinyede KA, Oyewusi HA, Hughes GD, Ekpo OE, Oguntibeju OO Molecules 28-Dec-2021
PMCID:PMC8746515
doi:10.3390/molecules27010155
PMID:35011387
Medicinal Properties and In Vitro Biological Activities of Selected Helichrysum Species from South Africa: A Review Akinyede KA, Cupido CN, Hughes GD, Oguntibeju OO, Ekpo OE Plants (Basel) 30-Jul-2021
PMCID:PMC8398148
doi:10.3390/plants10081566
PMID:34451611
Psychological ailments and their treatment protocols: a case study of Swati traditional healers in Mpumalanga Province, South Africa Ngobe A, Semenya S, Sodi T Afr Health Sci 01-Jun-2021
PMCID:PMC8568258
doi:10.4314/ahs.v21i2.50
PMID:34795748
In vitro evaluation of the anti-diabetic potential of Helichrysum petiolare Hilliard & B.L. Burtt using HepG2 (C3A) and L6 cell lines Aladejana AE, Bradley G, Afolayan AJ F1000Res 01-Apr-2021
PMCID:PMC8080987
doi:10.12688/f1000research.26855.1
PMID:33968374
Phytochemical Profiling and Quality Control of Terminalia sericea Burch. ex DC. Using HPTLC Metabolomics Mulaudzi N, Anokwuru CP, Tankeu SY, Combrinck S, Chen W, Vermaak I, Viljoen AM Molecules 15-Jan-2021
PMCID:PMC7830210
doi:10.3390/molecules26020432
PMID:33467662
The use of plant extracts and their phytochemicals for control of toxigenic fungi and mycotoxins Makhuvele R, Naidu K, Gbashi S, Thipe VC, Adebo OA, Njobeh PB Heliyon 22-Oct-2020
PMCID:PMC7586119
doi:10.1016/j.heliyon.2020.e05291
PMID:33134582
Are plants used in the Eastern Cape province for cosmetics fully commercialized? Sagbo IJ, Mbeng WO Indian J Pharmacol 01-May-2019
PMCID:PMC6644182
doi:10.4103/ijp.IJP_262_18
PMID:31391681
Multiple Polyploidization Events across Asteraceae with Two Nested Events in the Early History Revealed by Nuclear Phylogenomics Huang CH, Zhang C, Liu M, Hu Y, Gao T, Qi J, Ma H Mol Biol Evol 07-Sep-2016
PMCID:PMC5062320
doi:10.1093/molbev/msw157
PMID:27604225

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
(1S,8aS)-4,7-dimethyl-1-propan-2-yl-1,2,6,8a-tetrahydronaphthalene 163008442 Click to see CC1=CC2C(CC=C(C2=CC1)C)C(C)C 202.33 unknown https://doi.org/10.1016/0031-9422(89)80195-5
(3S)-3beta,8-Dimethyl-5beta-isopropyl-4,4abeta,5,6-tetrahydronaphthalene-2(3H)-one 10921986 Click to see CC1CC2C(CC=C(C2=CC1=O)C)C(C)C 218.33 unknown https://doi.org/10.1016/0031-9422(89)80195-5
3,8-dimethyl-5-propan-2-yl-4,4a,5,6-tetrahydro-3H-naphthalen-2-one 14282656 Click to see CC1CC2C(CC=C(C2=CC1=O)C)C(C)C 218.33 unknown https://doi.org/10.1016/0031-9422(89)80195-5
beta-CARYOPHYLLENE OXIDE 1742210 Click to see CC1(CC2C1CCC3(C(O3)CCC2=C)C)C 220.35 unknown https://doi.org/10.1016/0031-9422(89)80195-5
Caryophyllene epoxide 14350 Click to see CC1(CC2C1CCC3(C(O3)CCC2=C)C)C 220.35 unknown https://doi.org/10.1016/0031-9422(89)80195-5
Humulene 5281520 Click to see CC1=CCC(C=CCC(=CCC1)C)(C)C 204.35 unknown https://doi.org/10.1016/0031-9422(89)80195-5
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Aromadendrane sesquiterpenoids / 5,10-cycloaromadendrane sesquiterpenoids
(1aR,4R,4aR,7S,7aS,7bS)-1,1,4,7-tetramethyl-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulen-4-ol 162940145 Click to see CC1CCC2C1C3C(C3(C)C)CCC2(C)O 222.37 unknown https://doi.org/10.1016/0031-9422(89)80195-5
(1aS,4aS,7S,7aR,7bS)-1,1,7-trimethyl-4-methylidene-1a,2,3,4a,5,6,7a,7b-octahydrocyclopropa[h]azulen-7-ol 97032059 Click to see CC1(C2C1C3C(CCC3(C)O)C(=C)CC2)C 220.35 unknown https://doi.org/10.1016/0031-9422(89)80195-5
(7aR)-1,1,7-trimethyl-4-methylidene-1a,2,3,4a,5,6,7a,7b-octahydrocyclopropa[h]azulen-7-ol 5321422 Click to see CC1(C2C1C3C(CCC3(C)O)C(=C)CC2)C 220.35 unknown https://doi.org/10.1016/0031-9422(89)80195-5
Globulol 101716 Click to see CC1CCC2C1C3C(C3(C)C)CCC2(C)O 222.37 unknown https://doi.org/10.1016/0031-9422(89)80195-5
Ledum camphor 22297324 Click to see CC1CCC2C1C3C(C3(C)C)CCC2(C)O 222.37 unknown https://doi.org/10.1016/0031-9422(89)80195-5
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones
(6R,11S)-3-ethyl-4,10-dimethyl-11-(3-methylbut-2-enyl)-2-oxaspiro[5.5]undeca-3,9-diene-1,5-dione 162884205 Click to see CCC1=C(C(=O)C2(CCC=C(C2CC=C(C)C)C)C(=O)O1)C 302.40 unknown https://doi.org/10.1016/0031-9422(89)80195-5
3-Ethyl-4,10-dimethyl-11-(3-methylbut-2-enyl)-2-oxaspiro[5.5]undeca-3,9-diene-1,5-dione 162884204 Click to see CCC1=C(C(=O)C2(CCC=C(C2CC=C(C)C)C)C(=O)O1)C 302.40 unknown https://doi.org/10.1016/0031-9422(89)80195-5
> Organoheterocyclic compounds / Epoxides
(1R,3E,7E,11R)-3,7,10,10-tetramethyl-12-oxabicyclo[9.1.0]dodeca-3,7-diene 15647025 Click to see CC1=CCC(C2C(O2)CC(=CCC1)C)(C)C 220.35 unknown https://doi.org/10.1016/0031-9422(89)80195-5
3,7,10,10-Tetramethyl-12-oxabicyclo[9.1.0]dodeca-3,7-diene 78385038 Click to see CC1=CCC(C2C(O2)CC(=CCC1)C)(C)C 220.35 unknown https://doi.org/10.1016/0031-9422(89)80195-5
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 8-O-methylated flavonoids
5-Hydroxy-7,8-dimethoxyflavone 188316 Click to see COC1=C(C2=C(C(=C1)O)C(=O)C=C(O2)C3=CC=CC=C3)OC 298.29 unknown https://doi.org/10.1016/0031-9422(89)80195-5

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