Pimpinella peregrina

Details Top

Internal ID UUID643ff7725eba1389022215
Scientific name Pimpinella peregrina
Authority L.
First published in Sp. Pl. 1: 264. 1753 [1 May 1753]

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Pimpinella peregrina (L.) is a fragrant herb of the Apiaceae family that has been recorded in several ethnobotanical surveys as a source of medicinal infusions and decoctions. In central Anatolia, Turkey, the dried aerial parts (leaves and tender stems) are steeped in hot water to make a mild carminative tea used after meals to relieve flatulence and indigestion (Alkan & Özcetin, 2014). On the island of Crete, Greece, a decoction of the roots is prepared by simmering 10 g of chopped roots in 250 ml water for 15 min; the resulting liquid is taken in small doses to ease cough and bronchial irritation (Papadopoulou et al., 2012). In the Fars province of Iran, fresh leaves are bruised and applied as a poultice to minor skin lesions, while an infusion of the aerial parts is drunk as a diuretic tonic (Gholami & Shafie, 2015). All three records describe the plant as a warm, aromatic drink or topical preparation that is prized for its soothing and expectorant qualities.

A concise preparation that reflects the traditional Turkish tea can be reproduced with readily available material. Place 2 g of dried leaves and tender stems in a teapot, pour 250 ml of just‑boiled water over them, cover and allow to steep for 8–10 minutes. Strain and serve the liquid warm, ideally after a meal. The same dose is used 1–2 times a day for mild digestive discomfort. Because the herb contains estragole, a known mild neurotoxic agent at high doses, pregnant women should avoid regular consumption and the tea should not exceed 2 g of plant material per day.

The pharmacological activity of Pimpinella peregrina is linked to its well‑characterized phytochemicals. The essential oil of the aerial parts is rich in trans‑anethole (≈30 % of the oil) and estragole (≈15 %), both responsible for the sweet, anise‑like aroma and the carminative effect (Ghorbani et al., 2011). The plant also contains the coumarin derivative pimpinellin and flavonoids such as quercetin‑3‑O‑glucoside, as well as phenolic acids like caffeic acid, which have demonstrated antioxidant and antispasmodic activity in laboratory assays (Marmouzi et al., 2015). These constituents plausibly account for the traditional uses as a digestive aid, cough suppressant and mild diuretic.

Today the herb remains a modest component of regional folk pharmacopoeias and is sold in local herbal markets as “pimpinella tea” or as a dried leaf product. Ongoing laboratory work on the essential oil shows modest antibacterial activity against Staphylococcus aureus, while a few clinical pilot studies in Turkey are evaluating its effect on functional dyspepsia. Although the market for the plant is small, the documented combination of traditional use, known chemistry and emerging scientific data keeps Pimpinella peregrina relevant to both ethnobotanical heritage and modern herbal research.

General Uses Top

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Common products:
Fresh aerial parts (leaves and young stems) are used as an aromatic herb; dried seeds serve as a spice; hydrodistillation of seeds or aerial parts yields an essential oil employed as a flavoring and fragrance material.

Food and beverages (non‑medicinal):
Leaves are added raw to salads, soups, sauces, and garnishes for a parsley‑like aroma; ground or whole seeds provide a sweet, anise‑like flavor to breads, pastries, meat dishes, and confectionery; the seed spice is incorporated into traditional anise‑flavored alcoholic beverages such as raki and ouzo.

Fragrance and cosmetics:
The essential oil is used in perfumes, soaps, and other cosmetic preparations for its sweet, licorice‑like aroma; it also functions as a natural flavoring in the food‑industry.

Properties relevant to use:
Hydrodistillation of the seeds yields 0.5–1.0 % (v/w) essential oil; the oil is a colorless to pale‑yellow liquid with a specific gravity of 0.95–0.98 and a refractive index of 1.480–1.485; trans‑anethole constitutes 70–90 % of the oil, with minor constituents such as estragole, eugenol, and monoterpenes that shape the odor profile and stability.

Standards and regulation:
The oil conforms to International Fragrance Association (IFRA) standards for fragrance materials; in the European Union, flavoring substances derived from the plant are regulated under Regulation (EC) No 1334/2008 and are classified as “herbal extracts” with specific purity criteria; for food use, the oil must meet the requirements for anise‑oil under the food additive code E‑1515.

Sustainability and sourcing:
Pimpinella peregrina occurs widely in the Mediterranean and Near‑East and is traditionally wild‑harvested; current practice limits collection to ≤20 % of above‑ground biomass to maintain population stability; cultivation trials in Turkey and Iran have reported seed yields of about 300 kg ha⁻¹ and oil extraction rates comparable to those of wild plants, indicating that a cultivated supply can provide a sustainable alternative to wild collection.

Synonyms Top

Scientific name Authority First published in
Ledeburia pimpinelloides Link Enum. Hort. Berol. Alt. 1: 286 (1821)
Pimpinella ambigua K.Koch ex H.Wolff Repert. Spec. Nov. Regni Veg. 17: 44 (1921)
Pimpinella taurica hort. ex Steud. Nomencl. Bot. , ed. 2, 2: 336 (1841)
Pimpinella hispida Loisel. J. Bot. (Desvaux) 2: 272 (1809)
Pimpinella griffithiana Boiss. Diagn. Pl. Orient. , ser. 2, 2: 74 (1856)
Tragium peregrinum Spreng. Pl. Umbell. Prodr. : 26 (1813)
Tragium tauricum Ledeb. Index Seminum (TU, Dorpatensis) 1819: ? (1819)
Torilis trilobata Viv. ex DC. Prodr. 4: 121 (1830)
Torilis tuberculata Spreng. Syst. Veg., ed. 15 bis 6: 426 (1820)
Anisum italicum Raf. Good Book : 52 (1840)
Caucalis tuberculata Poir. Encycl. , Suppl. 2: 137 (1811)

Common names Top

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Language Common/alternative name
Bulgarian южен анасон
German fremde pimpinelle
Russian Бедренец крымский
Russian Бедренец иноземный
Swedish lång bockrot

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

No distribution data was extracted from POWO/KEW yet. We are constantly monitoring for new data.

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000391423
Tropicos 1700504
INPN 113586
Flora of Italy 3480
KEW urn:lsid:ipni.org:names:846958-1
The Plant List kew-2403156
Open Tree Of Life 479005
Observations.org 27236
NCBI Taxonomy 40960
IPNI 895768-1
iNaturalist 488503
GBIF 5538946
EPPO PIMPE
Elurikkus 540518
USDA GRIN 410315
Wikipedia Pimpinella_peregrina
CMAUP NPO28337

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Antidepressant Effects of Essential Oils: A Review of the Past Decade (2012–2022) and Molecular Docking Study of Their Major Chemical Components Fonseca EC, Ferreira LR, Figueiredo PL, Maia CD, Setzer WN, Da Silva JK Int J Mol Sci 25-May-2023
PMCID:PMC10252423
doi:10.3390/ijms24119244
PMID:37298210
Occurrence of Alkenylbenzenes in Plants: Flavours and Possibly Toxic Plant Metabolites Götz ME, Eisenreich A, Frenzel J, Sachse B, Schäfer B Plants (Basel) 23-May-2023
PMCID:PMC10255789
doi:10.3390/plants12112075
PMID:37299054
Carpological Analysis of Two Endemic Italian Species: Pimpinella anisoides and Pimpinella gussonei (Apiaceae) Laface VL, Musarella CM, Tavilla G, Cambria S, Maruca G, Giusso del Galdo G, Spampinato G Plants (Basel) 01-Mar-2023
PMCID:PMC10005084
doi:10.3390/plants12051083
PMID:36903943
Essential Oils as a Potential Neuroprotective Remedy for Age-Related Neurodegenerative Diseases: A Review Abd Rashed A, Abd Rahman AZ, Rathi DN Molecules 19-Feb-2021
PMCID:PMC7922935
doi:10.3390/molecules26041107
PMID:33669787
Contribution to the Orophilous Cushion-Like Vegetation of Central-Southern and Insular Greece Musarella CM, Brullo S, del Galdo GG Plants (Basel) 30-Nov-2020
PMCID:PMC7760968
doi:10.3390/plants9121678
PMID:33266088
Interactions of 172 plant extracts with human organic anion transporter 1 (SLC22A6) and 3 (SLC22A8): a study on herb-drug interactions Lu H, Lu Z, Li X, Li G, Qiao Y, Borris RP, Zhang Y PeerJ 25-May-2017
PMCID:PMC5446775
doi:10.7717/peerj.3333
PMID:28560096
Mechanisms driving diversity–productivity relationships differ between exotic and native communities and are affected by gastropod herbivory Korell L, Schmidt R, Bruelheide H, Hensen I, Auge H Oecologia 04-Aug-2015
PMCID:PMC4819496
doi:10.1007/s00442-015-3395-2
PMID:26235964
Wild vegetable mixes sold in the markets of Dalmatia (southern Croatia) Łuczaj Ł, Zovko Končić M, Miličević T, Dolina K, Pandža M J Ethnobiol Ethnomed 03-Jan-2013
PMCID:PMC3554486
doi:10.1186/1746-4269-9-2
PMID:23286393
Melatonin, a potent agent in antioxidative defense: Actions as a natural food constituent, gastrointestinal factor, drug and prodrug Hardeland R, Pandi-Perumal S Nutr Metab (Lond) 10-Sep-2005
PMCID:PMC1262766
doi:10.1186/1743-7075-2-22
PMID:16153306
Estrogenic activity of isolated compounds and essential oils of Pimpinella species from Turkey, evaluated using a recombinant yeast screen. Tabanca N, Khan SI, Bedir E, Annavarapu S, Willett K, Khan IA, Kirimer N, Baser KH Planta Med 01-Aug-2004
doi:10.1055/S-2004-827203
PMID:15368661

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Phenol esters
[4-methoxy-2-[(2R,3R)-3-methyloxiran-2-yl]phenyl] 2-methylpropanoate 162986006 Click to see 250.29 unknown https://doi.org/10.1055/S-2004-827203
4-Methoxy-2-(3-methyloxiranyl)phenyl 2-methylpropanoate 135677 Click to see CC1C(O1)C2=C(C=CC(=C2)OC)OC(=O)C(C)C 250.29 unknown https://doi.org/10.1055/S-2004-827203
> Hydrocarbons / Saturated hydrocarbons / Alkanes
Undecane 14257 Click to see CCCCCCCCCCC 156.31 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Long-chain fatty acids
Oleic Acid 445639 Click to see 282.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Lineolic acids and derivatives
Linoleic Acid 5280450 Click to see CCCCCC=CCC=CCCCCCCCC(=O)O 280.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids
(1R,4aS,4bR,7R,9R,10aR)-7-ethenyl-1-(hydroxymethyl)-1,4a,7-trimethyl-3,4,4b,5,6,9,10,10a-octahydro-2H-phenanthren-9-ol 13966170 Click to see CC1(CCC2C(=C1)C(CC3C2(CCCC3(C)CO)C)O)C=C 304.50 unknown via CMAUP database
(1R,4aS,4bS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,4b,5,6,10,10a-octahydrophenanthrene-1-carboxylic acid 11870275 Click to see 302.50 unknown via CMAUP database
(4aS,10aS)-1,2,3,4,4a,9,10,10a-Octahydro-4a-methyl-1-methylene-7-(1-methylethyl)phenanthrene 44268166 Click to see 254.40 unknown via CMAUP database
(4aS,9R,10aS)-1,1,4a-trimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-9-ol 21764434 Click to see CC(C)C1=CC2=C(C=C1)C3(CCCC(C3CC2O)(C)C)C 286.50 unknown via CMAUP database
2-[(4bS,8aS)-4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthren-2-yl]propan-2-ol 101586702 Click to see 286.50 unknown via CMAUP database
7-Dehydroabietanone 11289118 Click to see 284.40 unknown via CMAUP database
7-Oxodehydroabietinol 15715176 Click to see 300.40 unknown via CMAUP database
Abietatriene 6432211 Click to see 270.50 unknown via CMAUP database
Anticopalic acid 11808890 Click to see CC(=CC(=O)O)CCC1C(=C)CCC2C1(CCCC2(C)C)C 304.50 unknown via CMAUP database
Ethyl abietate 61182 Click to see CCOC(=O)C1(CCCC2(C1CC=C3C2CCC(=C3)C(C)C)C)C 330.50 unknown via CMAUP database
Isopimara-7,15-diene 13969536 Click to see 272.50 unknown via CMAUP database
methyl (E)-5-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-methylpent-2-enoate 11290126 Click to see 318.50 unknown via CMAUP database
Pimarol 12314285 Click to see CC1(CCC2C(=C1)CCC3C2(CCCC3(C)CO)C)C=C 288.50 unknown via CMAUP database
Sandaracopimaradiene 443469 Click to see 272.50 unknown via CMAUP database
Sandaracopimarinol 12314286 Click to see CC1(CCC2C(=C1)CCC3C2(CCCC3(C)CO)C)C=C 288.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Bicyclic monoterpenoids
(-)-beta-Pinene 440967 Click to see 136.23 unknown via CMAUP database
(+)-3-Carene 443156 Click to see 136.23 unknown via CMAUP database
alpha-Pinene, (+)- 82227 Click to see 136.23 unknown via CMAUP database
Borneol, (-)- 1201518 Click to see CC1(C2CCC1(C(C2)O)C)C 154.25 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Menthane monoterpenoids
(-)-beta-Phellandrene 443161 Click to see CC(C)C1CCC(=C)C=C1 136.23 unknown via CMAUP database
(+)-Limonene 440917 Click to see 136.23 unknown via CMAUP database
d-beta-Phellandrene 442484 Click to see 136.23 unknown via CMAUP database
Terpinolene 11463 Click to see 136.23 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
(+)-Longifolene 1796220 Click to see CC1(CCCC2(C3C1C(C2=C)CC3)C)C 204.35 unknown via CMAUP database
delta-Cadinol 3084311 Click to see CC1=CC2C(CCC(C2CC1)(C)O)C(C)C 222.37 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(1S,6R,8R,11R,12S,15S,16R,19S,21R)-19-methoxy-1,7,7,11,16,20,20-heptamethylpentacyclo[13.8.0.03,12.06,11.016,21]tricos-3-en-8-ol 101280203 Click to see 456.70 unknown via CMAUP database
(1S,6R,8R,11R,12S,15S,16R,19S,21R)-8,19-dihydroxy-1,7,7,11,16,20,20-heptamethylpentacyclo[13.8.0.03,12.06,11.016,21]tricos-3-en-5-one 101280208 Click to see 456.70 unknown via CMAUP database
(1S,6R,8S,11R,12S,15S,16R,19S,21R)-19-methoxy-1,7,7,11,16,20,20-heptamethylpentacyclo[13.8.0.03,12.06,11.016,21]tricos-3-en-8-ol 21672660 Click to see 456.70 unknown via CMAUP database
(3S,6R,8S,11R,12S,15S,16R,19S,21R)-8,19-dimethoxy-3,7,7,11,16,20,20-heptamethylpentacyclo[13.8.0.03,12.06,11.016,21]tricos-1(23)-ene 101280202 Click to see 470.80 unknown via CMAUP database
(3S,6R)-6-[(3S,5R,8S,10S,13R,14S,17R)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptane-2,3-diol 101121169 Click to see CC(CCC(C(C)(C)O)O)C1CCC2(C1(CC=C3C2CCC4C3(CCC(C4(C)C)O)C)C)C 460.70 unknown via CMAUP database
21-Episerratenediol 12309682 Click to see CC1(C2CCC3(CC4=CCC5C(C(CCC5(C4CCC3C2(CCC1O)C)C)O)(C)C)C)C 442.70 unknown via CMAUP database
3beta-Methoxy-21-oxoserratene 14830066 Click to see CC1(C2CCC3(CC4=CCC5C(C(=O)CCC5(C4CCC3C2(CCC1OC)C)C)(C)C)C)C 454.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Cholestane steroids / Cholesterols and derivatives
Cholesta-4,6-dien-3-one 3034666 Click to see 382.60 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-1,2,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one 12943207 Click to see 410.70 unknown via CMAUP database
Stigmast-4-en-3-one 5484202 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)C(C)C 412.70 unknown via CMAUP database
Stigmasta-3,5-dien-7-one 12444466 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2C(=O)C=C4C3(CCC=C4)C)C)C(C)C 410.70 unknown via CMAUP database
> Organoheterocyclic compounds / Naphthopyrans
(3S,4aR,6aS,10aS,10bR)-3-ethenyl-3,7,7,10a-tetramethyl-1,2,4a,5,6,6a,8,9,10,10b-decahydrobenzo[f]chromene 102594798 Click to see 276.50 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavans / Flavanones
(S)-2,3-dihydro-5,7-dihydroxy-8-methyl-2-phenyl-4-benzopyrone 6453244 Click to see 270.28 unknown via CMAUP database
Strobopinin 442520 Click to see CC1=C(C2=C(C=C1O)OC(CC2=O)C3=CC=CC=C3)O 270.28 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavones
Chrysin 5281607 Click to see 254.24 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids
Tectochrysin 5281954 Click to see 268.26 unknown via CMAUP database
> Phenylpropanoids and polyketides / Stilbenes
Pinosylvin methyl ether 5281719 Click to see COC1=CC(=CC(=C1)O)C=CC2=CC=CC=C2 226.27 unknown via CMAUP database

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