6-Hexopyranosyl-8-methoxy-2H-(1,3)benzodioxolo(6,5,4-cd)benzo(f)indol-5(6H)-one

Details

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Internal ID 48d99635-7645-48fe-836b-481596cfdc84
Taxonomy Alkaloids and derivatives > Aristolactams
IUPAC Name 14-methoxy-10-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,5-dioxa-10-azapentacyclo[9.7.1.02,6.08,19.013,18]nonadeca-1(18),2(6),7,11(19),12,14,16-heptaen-9-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C23H21NO9/c1-30-13-4-2-3-9-10(13)5-12-16-11(6-14-21(17(9)16)32-8-31-14)22(29)24(12)23-20(28)19(27)18(26)15(7-25)33-23/h2-6,15,18-20,23,25-28H,7-8H2,1H3
InChI Key GIDCUQKCIZAUKW-UHFFFAOYSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C23H21NO9
Molecular Weight 455.40 g/mol
Exact Mass 455.12163125 g/mol
Topological Polar Surface Area (TPSA) 138.00 Ų
XlogP 1.20

Synonyms

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6-Hexopyranosyl-8-methoxy-2H-[1,3]benzodioxolo[6,5,4-cd]benzo[f]indol-5(6H)-one
125335-36-6

2D Structure

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2D Structure of 6-Hexopyranosyl-8-methoxy-2H-(1,3)benzodioxolo(6,5,4-cd)benzo(f)indol-5(6H)-one

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.53% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.46% 91.11%
CHEMBL2581 P07339 Cathepsin D 97.98% 98.95%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 96.90% 96.77%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.90% 95.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 93.84% 89.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 93.58% 86.33%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 93.26% 92.62%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 92.57% 94.45%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 91.17% 94.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 90.28% 95.89%
CHEMBL3192 Q9BY41 Histone deacetylase 8 88.37% 93.99%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.51% 97.09%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 87.46% 97.14%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 87.02% 96.00%
CHEMBL2535 P11166 Glucose transporter 85.21% 98.75%
CHEMBL5925 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 85.11% 92.38%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.79% 99.23%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 84.60% 95.83%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 84.37% 82.67%
CHEMBL1994 P08235 Mineralocorticoid receptor 83.63% 100.00%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 83.11% 89.62%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Aristolochia indica
Aristolochia kaempferi
Aristolochia zollingeriana

Cross-Links

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PubChem 53462738
LOTUS LTS0211830
wikiData Q82635622