5,8,11,14-Icosatetraenoic Acid

Details

• Internal ID: 5df43c72-6207-44f6-b33b-ac2e00ff3e5c
• Taxonomy: Lipids and lipid-like molecules > Fatty Acyls > Fatty acids and conjugates > Long-chain fatty acids
• IUPAC Name: icosa-5,8,11,14-tetraenoic acid
• SMILES (Canonical): CCCCCC=CCC=CCC=CCC=CCCCC(=O)O
• SMILES (Isomeric): CCCCCC=CCC=CCC=CCC=CCCCC(=O)O
• InChI: InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)
• InChI Key: YZXBAPSDXZZRGB-UHFFFAOYSA-N
• Popularity: 13,766 references in papers

Physical and Chemical Properties

• Molecular Formula: C₂₀H₃₂O₂
• Molecular Weight: 304.50 g/mol
• Exact Mass: 304.240230259 g/mol
• Topological Polar Surface Area (TPSA): 37.30 Ų
• XlogP: 6.30

Synonyms

• 7771-44-0
• all-trans-Arachidonic acid
• 5,8,11,14-Icosatetraenoic Acid
• MFCD00004417
• Immunocytophyt;Immunocytophyte;Vevodar
• 5,8,11,14-Eicosatetraenoic acid, (5Z,8Z,11Z,14Z)-
• [3h]-arachidonic acid
• Spectrum_000091
• SpecPlus_000727
• Spectrum4_000905
• CBiol_001948
• KBioGR_000259
• KBioGR_001370
• KBioSS_000259
• KBioSS_000511
• DivK1c_006823
• KBio1_001767
• KBio2_000259
• KBio2_000511
• KBio2_002827
• KBio2_003079
• KBio2_005395
• KBio2_005647
• KBio3_000517
• KBio3_000518
• DTXSID50859424
• YZXBAPSDXZZRGB-UHFFFAOYSA-N
• Bio1_000234
• Bio1_000723
• Bio1_001212
• Bio2_000259
• Bio2_000739
• AKOS028108970
• SY045398
• FT-0619856
• FT-0621981
• FT-0622461
• FT-0622462
• CH3(CH2)4CH=CHCH2CH=CHCH2CH=CHCH2CH=CH(CH2)3COOH
• CH3(CH2)4-CH=CHCH2CH=CHCH2CH=CHCH2CH=CH(CH2)3COOH

2D Structure

ADMET Properties (via admetSAR 2)

Target	Value	Probability (raw)	Probability (%)
No predicted properties yet!

Targets

Proven Targets:

CHEMBL ID	UniProt ID	Name	Min activity	Assay type	Source
CHEMBL2903	P16050	Arachidonate 15-lipoxygenase	79.4 nM	Potency	via Super-PRED

Predicted Targets (via Super-PRED):

CHEMBL ID	UniProt ID	Name	Probability	Model accuracy
CHEMBL3060	Q9Y345	Glycine transporter 2	96.94%	99.17%
CHEMBL2581	P07339	Cathepsin D	96.77%	98.95%
CHEMBL1781	P11387	DNA topoisomerase I	93.41%	97.00%
CHEMBL3251	P19838	Nuclear factor NF-kappa-B p105 subunit	92.44%	96.09%
CHEMBL230	P35354	Cyclooxygenase-2	92.05%	89.63%
CHEMBL4769	O95749	Geranylgeranyl pyrophosphate synthetase	91.97%	92.08%
CHEMBL221	P23219	Cyclooxygenase-1	91.59%	90.17%
CHEMBL4793	Q86TI2	Dipeptidyl peptidase IX	82.87%	96.95%
CHEMBL3359	P21462	Formyl peptide receptor 1	82.54%	93.56%
CHEMBL2265	P23141	Acyl coenzyme A:cholesterol acyltransferase	80.44%	85.94%

Plants that contains it

• Hedlundia hybrida
• Populus balsamifera
• Rhytidiadelphus squarrosus
• Rhytidiadelphus triquetrus
• Stellaria dichotoma

Cross-Links

• PubChem: 231
• LOTUS: LTS0271804
• wikiData: Q27116784