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Haplophyllum cappadocicum

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Table of Contents

Details
Description
Synonyms
Common Names
Subtypes (subspecies, varieties, subvarieties, forms)
Germination/Propagation
Distribution
Links to other databases
Genome
Scientific Literature
Phytochemical Profile
Biological Material
Contributors
Collections

Details Top

Internal ID UUID64401fb6073f5406576722
Scientific name Haplophyllum cappadocicum
Authority Spach ex Jaub. & Spach
First published in Ill. Pl. Orient. 3: t. 263 (1848)

Description Top

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Synonyms Top

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Common names Top

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Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000715498
KEW urn:lsid:ipni.org:names:771265-1
Open Tree Of Life 520165
NCBI Taxonomy 1006070
IPNI 771265-1
GBIF 8165501
Elurikkus 646995

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Antimalarial drug discovery against malaria parasites through haplopine modification: An advanced computational approach Akash S, Abdelkrim G, Bayil I, Hosen ME, Mukerjee N, Shater AF, Saleh FM, Albadrani GM, Al‐Ghadi MQ, Abdel‐Daim MM, Tok TT J Cell Mol Med 19-Sep-2023
PMCID:PMC10568677
doi:10.1111/jcmm.17940
PMID:37724615
Chemistry and Biological Activities of Naturally Occurring and Structurally Modified Podophyllotoxins Jin L, Song Z, Cai F, Ruan L, Jiang R Molecules 30-Dec-2022
PMCID:PMC9822336
doi:10.3390/molecules28010302
PMID:36615496
Identification of Gedunin from a Phytochemical Depository as a Novel Multidrug Resistance-Bypassing Tubulin Inhibitor of Cancer Cells Khalid SA, Dawood M, Boulos JC, Wasfi M, Drif A, Bahramimehr F, Shahhamzehei N, Shan L, Efferth T Molecules 09-Sep-2022
PMCID:PMC9501561
doi:10.3390/molecules27185858
PMID:36144591
Justicidin B: A Promising Bioactive Lignan Hemmati S, Seradj H Molecules 23-Jun-2016
PMCID:PMC6272961
doi:10.3390/molecules21070820
PMID:27347906
Potent Cytotoxic Arylnaphthalene Lignan Lactones from Phyllanthus poilanei Ren Y, Lantvit DD, Deng Y, Kanagasabai R, Gallucci JC, Ninh TN, Chai HB, Soejarto DD, Fuchs JR, Yalowich JC, Yu J, Swanson SM, Kinghorn AD J Nat Prod 12-Jun-2014
PMCID:PMC4073661
doi:10.1021/np5002785
PMID:24937209
(-)-Padocin: A Novel Epoxygnan from Haplophyllum Cappadocicum Manfred Hesse, Belkis Gözler, Bijen Livçak, Gökay Arar, Tekant Gözler The Japan Institute of Heterocyclic Chemistry 04-Mar-2009
doi:10.3987/COM-94-S(B)19
Malatyamine, A 4-Quinolone Alkaloid from Haplophyllum cappadocicum Gökay Arar, Tekant Gözler, Mohammed Bashir, Maurice Shamma American Chemical Society (ACS) 30-May-2007
doi:10.1021/NP50040A022
Minor lignans from haplophyllum cappadocicum Belkis Gözler, Tekant Gözler, Hüsniye Saǧlam, Manfred Hesse Elsevier BV 23-Apr-2003
doi:10.1016/0031-9422(96)00061-1
Isodaurinol, an arylnaphthalene lignan from Haplophyllum cappadocicum Manfred Hesse, Belkis Gozler, Gokay Arar, Tekant Gozler Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(92)83302-F
Lignans and lignan glycosides fromHaplophyllum cappadocicum Belkis Go¨zler, Mustafa A. O¨nu¨r, Tekant Go¨zler, Gu¨lden Kadan, Manfred Hesse Elsevier BV 25-Jul-2002
doi:10.1016/S0031-9422(00)89594-1

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Methoxybenzoic acids and derivatives / M-methoxybenzoic acids and derivatives
Vanillic Acid 8468 Click to see COC1=C(C=CC(=C1)C(=O)O)O 168.15 unknown https://doi.org/10.1016/0031-9422(96)00061-1
> Benzenoids / Tetralins
12-[(4-Hydroxy-3-methoxyphenyl)methyl]-5-methoxy-11-oxatricyclo[7.2.1.02,7]dodeca-2,4,6-trien-4-ol 162930979 Click to see COC1=C(C=C2C3C(C(CC2=C1)CO3)CC4=CC(=C(C=C4)O)OC)O 342.40 unknown https://doi.org/10.3987/COM-94-S(B)19
> Lignans, neolignans and related compounds / Arylnaphthalene lignans
4-(1,3-benzodioxol-5-yl)-7-hydroxy-6-methoxy-1H-benzo[f][2]benzofuran-3-one 14704582 Click to see COC1=CC2=C(C3=C(COC3=O)C=C2C=C1O)C4=CC5=C(C=C4)OCO5 350.30 unknown https://doi.org/10.1016/0031-9422(92)83302-F
9-(1,3-benzodioxol-5-yl)-4,7-dihydroxy-6-methoxy-3H-benzo[f][2]benzofuran-1-one 101996845 Click to see COC1=C(C=C2C(=C1)C(=C3COC(=O)C3=C2C4=CC5=C(C=C4)OCO5)O)O 366.30 unknown https://doi.org/10.1016/S0031-9422(00)89594-1
https://doi.org/10.1016/0031-9422(96)00061-1
9-(1,3-benzodioxol-5-yl)-7-hydroxy-6-methoxy-3H-benzo[f][2]benzofuran-1-one 71543283 Click to see COC1=CC2=CC3=C(C(=C2C=C1O)C4=CC5=C(C=C4)OCO5)C(=O)OC3 350.30 unknown https://doi.org/10.1016/0031-9422(92)83302-F
Diphyllin 100492 Click to see COC1=C(C=C2C(=C1)C(=C3C(=C2O)COC3=O)C4=CC5=C(C=C4)OCO5)OC 380.30 unknown https://doi.org/10.1016/0031-9422(92)83302-F
Justicidin A 159982 Click to see COC1=C(C=C2C(=C1)C(=C3C(=C2OC)COC3=O)C4=CC5=C(C=C4)OCO5)OC 394.40 unknown https://doi.org/10.1016/0031-9422(92)83302-F
Justicidin B 442882 Click to see COC1=CC2=CC3=C(C(=C2C=C1OC)C4=CC5=C(C=C4)OCO5)C(=O)OC3 364.30 unknown https://doi.org/10.1016/0031-9422(92)83302-F
Retrochinensin 122805 Click to see COC1=C(C=C(C=C1)C2=C3C=C4C(=CC3=CC5=C2COC5=O)OCO4)OC 364.30 unknown https://doi.org/10.1016/0031-9422(92)83302-F
> Lignans, neolignans and related compounds / Furanoid lignans / Tetrahydrofuran lignans / 9,9-epoxylignans / Dibenzylbutyrolactone lignans
(+)-Matairesinol 11451194 Click to see COC1=C(C=CC(=C1)CC2COC(=O)C2CC3=CC(=C(C=C3)O)OC)O 358.40 unknown https://doi.org/10.1016/0031-9422(92)83302-F
> Lignans, neolignans and related compounds / Lignan glycosides
9-(1,3-benzodioxol-5-yl)-4-[(2S,3R,4R)-4-hydroxy-4-(hydroxymethyl)-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxolan-2-yl]oxy-6,7-dimethoxy-3H-benzo[f][2]benzofuran-1-one 14731302 Click to see COC1=C(C=C2C(=C1)C(=C3C(=C2OC4C(C(CO4)(CO)O)OC5C(C(C(CO5)O)O)O)COC3=O)C6=CC7=C(C=C6)OCO7)OC 644.60 unknown https://doi.org/10.1016/0031-9422(96)00061-1
9-(1,3-benzodioxol-5-yl)-4-[3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-6,7-dimethoxy-1H-benzo[f][2]benzofuran-3-one 162821327 Click to see COC1=C(C=C2C(=C1)C(=C3COC(=O)C3=C2OC4C(C(CO4)(CO)O)O)C5=CC6=C(C=C5)OCO6)OC 512.50 unknown https://doi.org/10.1016/0031-9422(96)00061-1
Cleistanthin B 119458 Click to see COC1=C(C=C2C(=C1)C(=C3C(=C2OC4C(C(C(C(O4)CO)O)O)O)COC3=O)C5=CC6=C(C=C5)OCO6)OC 542.50 unknown https://doi.org/10.1016/S0031-9422(00)89594-1
> Organoheterocyclic compounds / Quinolines and derivatives / Furanoquinolines
4,8-dimethoxy-9H-furo[2,3-b]quinolin-7-one 165368 Click to see COC1=C2C=CC(=O)C(=C2NC3=C1C=CO3)OC 245.23 unknown https://doi.org/10.1016/0031-9422(92)83302-F
Dictamnine 68085 Click to see COC1=C2C=COC2=NC3=CC=CC=C31 199.20 unknown https://doi.org/10.1016/0031-9422(92)83302-F
Haplopine 5281846 Click to see COC1=C2C=COC2=NC3=C1C=CC(=C3OC)O 245.23 unknown https://doi.org/10.1016/0031-9422(92)83302-F
Robustine 164950 Click to see COC1=C2C=COC2=NC3=C1C=CC=C3O 215.20 unknown https://doi.org/10.1016/0031-9422(92)83302-F
Skimmianine 6760 Click to see COC1=C(C2=C(C=C1)C(=C3C=COC3=N2)OC)OC 259.26 unknown https://doi.org/10.1016/0031-9422(92)83302-F
> Organoheterocyclic compounds / Quinolines and derivatives / Quinolones and derivatives / Hydroquinolones
6-(4-oxo-1H-quinolin-2-yl)hexanoic acid 162974663 Click to see C1=CC=C2C(=C1)C(=O)C=C(N2)CCCCCC(=O)O 259.30 unknown https://doi.org/10.1021/NP50040A022
> Phenylpropanoids and polyketides / Coumarins and derivatives / Hydroxycoumarins / 7-hydroxycoumarins
Scopoletin 5280460 Click to see COC1=C(C=C2C(=C1)C=CC(=O)O2)O 192.17 unknown https://doi.org/10.1016/0031-9422(92)83302-F
> Phenylpropanoids and polyketides / Coumarins and derivatives / Pyranocoumarins / Angular pyranocoumarins
Seselin 68229 Click to see CC1(C=CC2=C(O1)C=CC3=C2OC(=O)C=C3)C 228.24 unknown https://doi.org/10.1016/0031-9422(92)83302-F

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