Stephania rotunda
Details Top
| Internal ID | UUID64400516b7a1c562656530 |
| Scientific name | Stephania rotunda |
| Authority | Lour. |
| First published in | Fl. Cochinch. : 608 (1790) |
General Uses Top
Suggest a correction!Food and beverages (non-medicinal):
The tuberous root is processed into a starch flour used in East and Southeast Asian cuisines, most commonly as a wheat-flour substitute in noodles and batters and as a frying and breading starch. The product is marketed as “shan yao fen” (Dioscorea) in some Chinese markets but is botanically sourced from Stephania rotunda. In Chinese commerce, Stephania-derived starch is sometimes blended with Dioscorea oppositifolia starch and labeled “shan yao fen,” creating potential consumer confusion.
Scientific/model-organism use:
Stephania rotunda tubers are used as a raw material for isolation of the bisbenzylisoquinoline alkaloid tetrandrine. This compound serves as a reference standard in phytochemical studies and as a pharmacological probe in cell biology. Published protocols describe extraction and high-performance liquid chromatography (HPLC) quantification for quality control in research workflows; total alkaloid content and tetrandrine concentrations are commonly reported. Tissue culture systems derived from S. rotunda are used to investigate alkaloid biosynthesis and callus induction.
Properties relevant to use:
The tuber starch exhibits high amylose content, contributing to rapid retrogradation and firm gel texture in cooked products, which is desirable for noodles and fried coatings. No documented wood, fiber, colorant, tannin, fragrance, or resin uses are reported. Tetrandrine’s isoquinoline structure and reported pharmacological activity underpin its role as a laboratory probe; no non-medicinal commercial applications of this alkaloid are established.
Standards and regulation:
tuber starch is subject to general national food starch standards (e.g., ISO 1666 for starch composition; national food additives labeling and purity specifications), and tetrandrine isolated for research follows laboratory reagent guidelines.
Sustainability and sourcing:
harvest of wild tubers carries a risk of overexploitation; commercial starch supply is inconsistent due to taxonomic confusion with Dioscorea species and limited cultivated material. Standardized, lab-grade tetrandrine is produced in specialized extraction facilities; research use is generally less impacted than food starch supply.
Synonyms Top
| Scientific name | Authority | First published in |
|---|---|---|
| Menispermum roxburghii | Spreng. | Syst. Veg. 2: 155 (1825) |
| Stephania hexandra | Miers | Ann. Mag. Nat. Hist. , ser. 2, 7: 40 (1851) |
| Cissampelos glabra | Roxb. | Fl. Ind. ed. 1832 , 3: 840 (1832) |
| Clypea glabra | (Roxb.) Wight & Arn. ex Voigt | Hort. Suburb. Calcutt. : 330 (1845) |
| Clypea rotunda | Steud. | Nomencl. Bot. , ed. 2, 1: 387 (1840) |
| Cocculus finlaysonianus | Wall. | Numer. List [Wallich] n. 4974. [1831-32] |
| Stephania glabra | (Roxb.) Miers | Ann. Mag. Nat. Hist. , ser. 2, 18: 14 (1866) |
| Menispermum japonicum | Roxb. ex DC. | Syst. Nat. 1: 516 (1817) |
Germination/Propagation Top
Suggest a correction or add new data!
No germination or propagation data was added yet.
Distribution (via POWO/KEW) Top
Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
-
Asia-temperate click to expand
-
China
- Tibet
-
China
-
Asia-tropical click to expand
-
Indian Subcontinent
- Assam
- Bangladesh
- East Himalaya
- India
- Nepal
- West Himalaya
-
Indo-China
- Cambodia
- Laos
- Myanmar
- Thailand
- Vietnam
-
Indian Subcontinent
Links to other databases Top
Suggest others/fix!| Database | ID/link to page |
|---|---|
| World Flora Online | wfo-0000505063 |
| Tropicos | 20600012 |
| KEW | urn:lsid:ipni.org:names:581482-1 |
| Open Tree Of Life | 576462 |
| NCBI Taxonomy | 461634 |
| IPNI | 581482-1 |
| GBIF | 5592764 |
| Elurikkus | 552682 |
| USDA GRIN | 35530 |
| CMAUP | NPO24050 |
Genomes (via NCBI) Top
No reference genome is available on NCBI yet. We are constantly monitoring for new data.
Scientific Literature Top
Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Phytochemical Profile Top
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Below are displayed the proven (via scientific papers) natural compounds!
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| Name | PubChem ID | Canonical SMILES | MW | Found in | Proof |
|---|---|---|---|---|---|
| > Alkaloids and derivatives / Aporphines | |||||
| 1,2-Dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-ol | 494626 | Click to see COC1=C(C2=C3C(CC4=C2C=C(C=C4)O)NCCC3=C1)OC | 297.30 | unknown | https://doi.org/10.1248/YAKUSHI1947.86.10_871 |
| Roemerine | 119204 | Click to see CN1CCC2=CC3=C(C4=C2C1CC5=CC=CC=C54)OCO3 | 279.30 | unknown | via CMAUP database |
| Tsuduranine | 363262 | Click to see COC1=C(C2=C3C(CC4=C2C=C(C=C4)O)NCCC3=C1)OC | 297.30 | unknown | https://doi.org/10.1248/YAKUSHI1947.86.10_871 |
| > Alkaloids and derivatives / Hasubanan alkaloids | |||||
| (-)-Cepharamine | 5315777 | Click to see | 329.40 | unknown | https://doi.org/10.1021/NP50038A038 |
| > Alkaloids and derivatives / Proaporphines | |||||
| N-Acetylstepharine | 759300 | Click to see | 339.40 | unknown | https://doi.org/10.1248/YAKUSHI1947.101.10_951 |
| Pronuciferine | 200480 | Click to see CN1CCC2=CC(=C(C3=C2C1CC34C=CC(=O)C=C4)OC)OC | 311.40 | unknown | via CMAUP database |
| Pronuciferine, (-)- | 793841 | Click to see CN1CCC2=CC(=C(C3=C2C1CC34C=CC(=O)C=C4)OC)OC | 311.40 | unknown | via CMAUP database |
| Stepharine | 193686 | Click to see | 297.30 | unknown | via CMAUP database |
| > Alkaloids and derivatives / Protoberberine alkaloids and derivatives | |||||
| (13aS)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-11-ol | 12442995 | Click to see | 371.40 | unknown | https://doi.org/10.1248/YAKUSHI1947.86.10_871 |
| 2,3,10-trimethoxy-6,7-dihydro-5H-isoquinolino[2,1-b]isoquinolin-7-ium-9-one | 101280139 | Click to see | 338.40 | unknown | via CMAUP database |
| 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-11-ol | 12442994 | Click to see COC1=C(C=C2C3CC4=CC(=C(C(=C4CN3CCC2=C1)OC)OC)O)OC | 371.40 | unknown | https://doi.org/10.1248/YAKUSHI1947.86.10_871 |
| D-Tetrahydropalmatine | 969488 | Click to see COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC | 355.40 | unknown | via CMAUP database |
| Dehydrocorydalmine | 3083983 | Click to see COC1=C(C=C2C(=C1)CC[N+]3=C2C=C4C=CC(=C(C4=C3)OC)O)OC | 338.40 | unknown | via CMAUP database |
| Hydroxyl-palmatine | 46216998 | Click to see | 368.40 | unknown | via CMAUP database |
| Palmatine | 19009 | Click to see | 352.40 | unknown | via CMAUP database |
| Stepharanine | 10358881 | Click to see | 324.30 | unknown | via CMAUP database |
| Stepholidine | 6917970 | Click to see | 327.40 | unknown | via CMAUP database |
| Tetrahydropalmatine | 72301 | Click to see COC1=C(C2=C(CC3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC | 355.40 | unknown | via CMAUP database |
| > Lignans, neolignans and related compounds | |||||
| (14R,27R)-22,33-dimethoxy-13-methyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.216,19.13,10.121,25.04,8.031,35.014,39]nonatriaconta-1(33),3(39),4(8),9,16(38),17,19(37),21,23,25(36),31,34-dodecaene | 44559014 | Click to see | 592.70 | unknown | https://doi.org/10.1080/14786410903395624 |
| 22,33-Dimethoxy-13-methyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.216,19.13,10.121,25.04,8.031,35.014,39]nonatriaconta-1(33),3(39),4(8),9,16(38),17,19(37),21,23,25(36),31,34-dodecaene | 14488280 | Click to see | 592.70 | unknown | https://doi.org/10.1080/14786410903395624 |
| 33-Methoxy-13,28-dimethyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.216,19.13,10.121,25.04,8.031,35.014,39]nonatriaconta-1(33),3(39),4(8),9,16(38),17,19(37),21,23,25(36),31,34-dodecaen-22-ol | 9808633 | Click to see | 592.70 | unknown | https://doi.org/10.1080/14786410903395624 |
| Cepharanoline | 5315779 | Click to see | 592.70 | unknown | https://doi.org/10.1080/14786410903395624 |
| Fangchinoline | 73481 | Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)O)OC)OC | 608.70 | unknown | https://doi.org/10.1080/14786410903395624 |
| Isofangchinoline | 321937 | Click to see CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)O)OC)OC | 608.70 | unknown | https://doi.org/10.1080/14786410903395624 |
| > Organic oxygen compounds / Organooxygen compounds / Ethers / Diarylethers | |||||
| (11R,26R)-4,5,19,20-tetramethoxy-10-methyl-2,17-dioxa-10,25-diazaheptacyclo[26.2.2.213,16.13,7.118,22.011,36.026,33]hexatriaconta-1(31),3(36),4,6,13,15,18(33),19,21,28(32),29,34-dodecaene | 21582963 | Click to see | 608.70 | unknown | via CMAUP database |
| (11R,27R)-4,5,20,21-tetramethoxy-10,26-dimethyl-2,18-dioxa-10,26-diazaheptacyclo[27.2.2.13,7.113,17.119,23.011,36.027,34]hexatriaconta-1(32),3(36),4,6,13(35),14,16,19(34),20,22,29(33),30-dodecaene | 53486320 | Click to see | 622.70 | unknown | via CMAUP database |
| Cycleanine | 121313 | Click to see CN1CCC2=CC(=C(C3=C2C1CC4=CC=C(C=C4)OC5=C6C(CC7=CC=C(O3)C=C7)N(CCC6=CC(=C5OC)OC)C)OC)OC | 622.70 | unknown | via CMAUP database |
| > Organosulfur compounds / Thiocarbonyl compounds / Thioaldehydes / Thioaldehyde s-oxides | |||||
| thiopropanal S-oxide | 441491 | Click to see | 90.15 | unknown | via CMAUP database |
Collections Top
| In private collections | 0 |
| In public collections | 0 |