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Internal ID UUID644002e8bf5aa897138076
Scientific name Piper wightii
Authority Miq.
First published in London J. Bot. 5: 552 (1846)

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Among hill peoples of the Western Ghats, Piper wightii leaves are taken as a tea or decoction for stomach upsets, abdominal colic, and cough. According to Trivedi, 1984, people in the Nilgiris of southern India prepare a leaf tea for “wind and indigestion” and the same decoction is used in some hill villages as a gentle expectorant. In the Andaman Islands, the stem bark is chewed or made into a decoction for digestive discomfort, a use recorded by Dagar and Dagar, 1991. Sharma and Ahmed, 1985, report that Naga communities in northeast India decoct the leaves as a carminative and for cough relief, while in Kerala, the fresh leaves are made into a poultice applied to minor wounds, bruises, or joint sprains, and a weak infusion is sometimes taken for indigestion, as noted in the traditional knowledge collection of Jain, 1991.

An easy traditional method is a mild leaf tea. Use 2–3 fresh leaves (about 3–5 g) per 200 ml near-boiling water, cover and steep 10–12 minutes, then cool and sip 1 cup 2–3 times daily. Alternatively, a 1:5 (w/v) tincture is made by adding 25 g of finely chopped fresh leaves to 125 ml of 40% alcohol, macerating for 2 weeks with daily shaking, then straining and filtering. The final tincture keeps in a dark bottle. Adult oral dose is 1–2 ml diluted in water up to twice daily. Do not exceed 3 g of leaf material per day in tincture equivalents; avoid during pregnancy and lactation, and stop if heartburn or mouth irritation occurs.

The known active constituents for this species include piperine and other piperamides, together with monoterpenes (alpha- and beta-pinene, sabinene), sesquiterpenes (beta-caryophyllene), phenylpropanoids (safrole), and tannins, which together give a warming, antispasmodic, and mildly antimicrobial profile. Modern research continues to focus on piperine and related amides for their bioactivity, though clinical evidence is still limited.

Today, Piper wightii is not widely commercialized, but it remains a modest component of regional ethnoveterinary practice, especially for digestive complaints in goats, and local practitioners in the Western Ghats still ask for it during seasonal flu and “wind” periods (Sahni, 1986).

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Database ID/link to page
World Flora Online wfo-0000487381
KEW urn:lsid:ipni.org:names:683980-1
Open Tree Of Life 5699486
NCBI Taxonomy 1508052
GBIF 4187202
CMAUP NPO9298
IPNI 683980-1

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Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Title Authors Publication Released IDs
Neolignans, cyclohexanes and alkaloids from <i>Piper wightii</i> Per M. Boll, Ashok K. Prasad, Om D. Tyagi, Jesper Wengel, Carl E. Olsen, Naresh Kumar, Kirpal S. Bisht, Virinder S. Parmar Wiley 13-Sep-2010
doi:10.1002/RECL.19961150103
Benzofuranoid Neolignans from Piper wightii Miq.. Om Dutt Tyagi, Jesper Wengel, Ashok K. Prasad, Per M. Boll, Carl E. Olsen, Hari N. Pati, Kirpal S. Bisht, Virinder S. Parmar, George W. Francis Danish Chemical Society 19-Jun-2008
doi:10.3891/ACTA.CHEM.SCAND.48-1007
Lignans and neolignans from stems and fruits of Piper wightii Ashok K. Prasad, Om D. Tyagi, Jesper Wengel, Per M. Boll, Carl E. Olsen, Nawal K. Sharma, Kirpal S. Bisht, Suman Gupta, Virinder S. Parmar Elsevier BV 25-Jul-2002
doi:10.1016/S0040-4020(01)85081-X
Lignans and neolignans from stems of Piper wightii Ashok K. Prasad, Om Dutt Tyagi, Jesper Wengel, Per M. Boll, Carl E. Olsen, Suman Gupta, Nawal K. Sharma, Kirpal S. Bisht, Virinder S. Parmar Elsevier BV 25-Jul-2002
doi:10.1016/S0040-4020(01)89597-1

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives / Gallic acid and derivatives
Syringic Acid 10742 Click to see 198.17 unknown via CMAUP database
> Benzenoids / Benzene and substituted derivatives / Methoxybenzenes / Dimethoxybenzenes
2-(3,4-Dimethoxyphenyl)-3a,7a-dimethoxy-3-methyl-5-prop-2-enyl-2,3,6,7-tetrahydro-1-benzofuran-6-ol 163099428 Click to see 390.50 unknown https://doi.org/10.3891/ACTA.CHEM.SCAND.48-1007
2-(3,4-dimethoxyphenyl)-3a,7a-dimethoxy-3-methyl-5-prop-2-enyl-3,7-dihydro-2H-1-benzofuran-6-one 74650024 Click to see 388.50 unknown https://doi.org/10.3891/ACTA.CHEM.SCAND.48-1007
> Benzenoids / Phenanthrenes and derivatives / Phenanthrols
10-Amino-3-methoxyphenanthren-4-ol 163194345 Click to see 239.27 unknown https://doi.org/10.1002/RECL.19961150103
> Lignans, neolignans and related compounds / Furanoid lignans / Tetrahydrofuran lignans / 7,7-epoxylignans
(-)-Machilusin 45268387 Click to see CC1C(C(OC1C2=CC3=C(C=C2)OCO3)C4=CC(=C(C=C4)OC)OC)C 356.40 unknown https://doi.org/10.1016/S0040-4020(01)85081-X
5-[(2R,3R,4R,5S)-5-(3,4-dimethoxyphenyl)-3,4-dimethyloxolan-2-yl]-1,3-benzodioxole 12302264 Click to see CC1C(C(OC1C2=CC3=C(C=C2)OCO3)C4=CC(=C(C=C4)OC)OC)C 356.40 unknown https://doi.org/10.1016/S0040-4020(01)85081-X
Calopiptin 12302265 Click to see 356.40 unknown https://doi.org/10.1016/S0040-4020(01)85081-X
Machilin G 10450921 Click to see 356.40 unknown https://doi.org/10.1016/S0040-4020(01)85081-X
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Aromatic monoterpenoids
2,5-Cyclohexadien-1-one, 4-[2-(3,4-dimethoxyphenyl)-1-methylethyl]-4,5-dimethoxy-2-(2-propenyl)-, [S-(R*,S*)]-; (4S)-4-[(1R)-2-(3,4-Dimethoxyphenyl)-1-methylethyl]-4,5-dimethoxy-2-(2-propen-1-yl)-2,5-cyclohexadien-1-one 129316665 Click to see 372.50 unknown https://doi.org/10.1016/S0040-4020(01)85081-X
Isoxanthochymol 10461245 Click to see 602.80 unknown via CMAUP database
Wallichinine 5315280 Click to see 370.40 unknown https://doi.org/10.1016/S0040-4020(01)85081-X
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Bicyclic monoterpenoids
(4R)-4-[(1R,2R)-1-(1,3-benzodioxol-5-yl)-1-hydroxypropan-2-yl]-4,5-dimethoxy-2-prop-2-enylcyclohexa-2,5-dien-1-one 162909009 Click to see CC(C(C1=CC2=C(C=C1)OCO2)O)C3(C=C(C(=O)C=C3OC)CC=C)OC 372.40 unknown https://doi.org/10.1016/S0040-4020(01)85081-X
4-[1-(1,3-Benzodioxol-5-yl)propan-2-yl]-4,5-dimethoxy-2-prop-2-enylcyclohexa-2,5-dien-1-one 44715837 Click to see 356.40 unknown https://doi.org/10.1016/S0040-4020(01)85081-X
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Iridoid O-glycosides
Methyl 5-hydroxy-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-7-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxymethyl]-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate 162965798 Click to see CC1C(C(C(C(O1)OCC2=CC(C3C2C(OC=C3C(=O)OC)OC4C(C(C(C(O4)CO)O)O)O)O)O)O)O 550.50 unknown https://doi.org/10.1016/S0040-4020(01)89597-1
> Organic acids and derivatives / Carboxylic acids and derivatives / Tricarboxylic acids and derivatives
(1R,2R)-1,2-dihydroxypropane-1,2,3-tricarboxylic acid 13037289 Click to see 208.12 unknown via CMAUP database
> Organoheterocyclic compounds / Benzodioxoles
(2R,3S,3aS,7S,7aS)-2-(1,3-benzodioxol-5-yl)-3a,4-dimethoxy-3-methyl-7-prop-2-enyl-2,3,7,7a-tetrahydro-1-benzofuran-6-one 162901880 Click to see 372.40 unknown https://doi.org/10.1016/S0040-4020(01)89597-1
2-(1,3-Benzodioxol-5-yl)-3a,4-dimethoxy-3-methyl-7-prop-2-enyl-2,3,7,7a-tetrahydro-1-benzofuran-6-one 4485346 Click to see CC1C(OC2C1(C(=CC(=O)C2CC=C)OC)OC)C3=CC4=C(C=C3)OCO4 372.40 unknown https://doi.org/10.1016/S0040-4020(01)89597-1
2-(1,3-Benzodioxol-5-yl)-3a,7a-dimethoxy-3-methyl-5-prop-2-enyl-2,3,6,7-tetrahydro-1-benzofuran-6-ol 85095150 Click to see 374.40 unknown https://doi.org/10.3891/ACTA.CHEM.SCAND.48-1007
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / 2,2-dimethyl-1-benzopyrans
6-(2,2-Dimethylchromen-6-yl)-2,2-dimethylchromen-8-ol 24882249 Click to see 334.40 unknown via CMAUP database
6-(4-Hydroxyphenyl)-2,2-dimethylchromen-8-ol 24882248 Click to see 268.31 unknown via CMAUP database
6-[2,2-Dimethyl-8-(3-methylbut-2-enyl)chromen-6-yl]-2,2-dimethylchromen-8-ol 24882247 Click to see CC(=CCC1=CC(=CC2=C1OC(C=C2)(C)C)C3=CC4=C(C(=C3)O)OC(C=C4)(C)C)C 402.50 unknown via CMAUP database
6-[4-Hydroxy-3-(3-methylbut-2-enyl)phenyl]-2,2-dimethylchromen-8-ol 24882170 Click to see 336.40 unknown via CMAUP database
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones
(1R,13R,15R)-15-[(2E)-3,7-dimethylocta-2,6-dienyl]-6,7-dihydroxy-16,16-dimethyl-1,13-bis(3-methylbut-2-enyl)-3-oxatetracyclo[11.3.1.02,11.04,9]heptadeca-2(11),4,6,8-tetraene-10,12,17-trione 25209203 Click to see 600.80 unknown via CMAUP database
(1R,13R,15S)-15-[(2E)-3,7-dimethylocta-2,6-dienyl]-6,7-dihydroxy-16,16-dimethyl-1,13-bis(3-methylbut-2-enyl)-3-oxatetracyclo[11.3.1.02,11.04,9]heptadeca-2(11),4,6,8-tetraene-10,12,17-trione 25209205 Click to see 600.80 unknown via CMAUP database
Euxanthone 5281631 Click to see 228.20 unknown via CMAUP database
Griffipavixanthone 60151566 Click to see 652.60 unknown via CMAUP database
Norathyriol 5281656 Click to see 260.20 unknown via CMAUP database
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones / 2-prenylated xanthones
1,3,7-Trihydroxy-2-(3-methylbut-2-enyl)-xanthone 5495920 Click to see 312.30 unknown via CMAUP database
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones / 4-prenylated xanthones
4-[(2E)-3,7-dimethylocta-2,6-dienyl]-1,5,6-trihydroxy-3-methoxy-7-(3-methylbut-2-enyl)xanthen-9-one 25209201 Click to see 478.60 unknown via CMAUP database
Dulxanthone B 10787706 Click to see 410.50 unknown via CMAUP database
nigrolineaxanthone T 11559542 Click to see CC(C)(CCC1=C(C=C(C2=C1OC3=C(C2=O)C=CC(=C3O)O)O)OC)O 360.40 unknown via CMAUP database
Nigrolineaxanthone V 11553272 Click to see 408.40 unknown via CMAUP database
Parvifolixanthone B 16085281 Click to see CC(=CCC1=CC2=C(C(=C1O)O)OC3=C(C2=O)C(=CC(=C3CC=C(C)C)OC)O)C 410.50 unknown via CMAUP database
Xanthone V2A 70695342 Click to see 426.50 unknown via CMAUP database
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones / 8-prenylated xanthones
Garcinone E 10298511 Click to see 464.50 unknown via CMAUP database
> Organoheterocyclic compounds / Benzopyrans / 1-benzopyrans / Xanthones / Pyranoxanthones
O-Demethylforbexanthone 45269778 Click to see CC1(C=CC2=CC3=C(C(=C2O1)O)OC4=CC(=CC(=C4C3=O)O)O)C 326.30 unknown via CMAUP database
Oblongixanthone A 25209069 Click to see 326.30 unknown via CMAUP database
Rheediaxanthone A 102060338 Click to see 392.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / 2-arylbenzofuran flavonoids
(2R,3R,3aS)-2-(1,3-benzodioxol-5-yl)-3a-methoxy-3-methyl-5-prop-2-enyl-2,3-dihydro-1-benzofuran-6-one 101028083 Click to see 340.40 unknown https://doi.org/10.3891/ACTA.CHEM.SCAND.48-1007
(3aR)-2-(1,3-benzodioxol-5-yl)-5-methoxy-3-methyl-3a-prop-2-enyl-2,3-dihydro-1-benzofuran-6-one 129317304 Click to see 340.40 unknown https://doi.org/10.3891/ACTA.CHEM.SCAND.48-1007
2-(1,3-Benzodioxol-5-yl)-3a-methoxy-3-methyl-5-prop-2-enyl-2,3-dihydro-1-benzofuran-6-one 13336516 Click to see CC1C(OC2=CC(=O)C(=CC12OC)CC=C)C3=CC4=C(C=C3)OCO4 340.40 unknown https://doi.org/10.3891/ACTA.CHEM.SCAND.48-1007
Hancinone 101370414 Click to see 340.40 unknown https://doi.org/10.3891/ACTA.CHEM.SCAND.48-1007
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives
1-Cinnamoylpyrrolidine 765514 Click to see C1CCN(C1)C(=O)C=CC2=CC=CC=C2 201.26 unknown https://doi.org/10.1002/RECL.19961150103
> Phenylpropanoids and polyketides / Isoflavonoids / Isoflav-2-enes / Isoflavones
Daidzein 5281708 Click to see 254.24 unknown via CMAUP database
Genistein 5280961 Click to see 270.24 unknown via CMAUP database
Isoprunetin 5748551 Click to see 284.26 unknown via CMAUP database
> Phenylpropanoids and polyketides / Stilbenes
(6R)-6-[(2R)-1-(1,3-benzodioxol-5-yl)propan-2-yl]-3,4-dimethoxy-6-prop-2-enylcyclohexa-2,4-dien-1-one 162883443 Click to see CC(CC1=CC2=C(C=C1)OCO2)C3(C=C(C(=CC3=O)OC)OC)CC=C 356.40 unknown https://doi.org/10.1016/S0040-4020(01)89597-1

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