Hypericum calycinum - Unknown
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Internal ID UUID6440214a91790538627475
Scientific name Hypericum calycinum
Authority L.
First published in Mant. Pl. 1: 106 (1767)

Description Top

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Hypericum calycinum, also known as Rose-of-Sharon or Aaron's beard, is a low-growing shrub with large yellow flowers. It is native to southeast Europe and southwest Asia, but is widely cultivated in Mediterranean climates and can be found in the Strandja Mountains along the Bulgarian and Turkish Black Sea coast. This species has been used traditionally for medicinal purposes and is now commonly used for ornamental and landscaping purposes in North America. It is a resilient plant that grows best in well-drained acidic soil and can become invasive if not properly maintained. Recent research has shown that the plant's UV pigments serve as a defense mechanism against predators and also attract pollinators. Extracts from this plant have also been found to have antidepressant effects without the side effects commonly associated with other antidepressant drugs.

Synonyms Top

Scientific name Authority First published in
Norysca calycina (L.) Blume Mus. Bot. 2: 22 (1856)
Norysca venosa (Lam.) Blume Mus. Bot. 2: 22 (1856)
Androsaemum calycinum (L.) T.Lestib. Botanogr. Belg. 2: 346 (1827)
Ascyrum calicinum (L.) Poir. Tabl. Encycl. 3: 199 (1823)
Ascyrum coriaceum Moench Methodus : 130 (1794)
Eremanthe calycina (L.) Spach Hist. Nat. Vég. 5: 422 (1836)
Eremanthe venosa (Lam.) K.Koch Hort. Dendrol. : 65 (1853)
Hypericum grandiflorum Salisb. Prodr. Stirp. Chap. Allerton : 369 (1796)
Hypericum venosum Lam. Encycl. 4: 146 (1797)
Hypericum calycinum var. acutifolium Choisy Prodr. [A. P. de Candolle] 1: 546. 1824
Hypericum calycinum f. luteum N.Robson Phytotaxa 72: 9. 2012 [16 Nov 2012] [epublished]

Common names Top

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Language Common/alternative name
English rose-of-sharon
English great st-john's wort
English creeping st. john's wort
English jerusalem star
English aaron's beard
Spanish hipérico rastrero
Bulgarian чашковидна звъника
Czech třezalka kalíškatá
Welsh rhosyn saron
Danish storblomstret perikon
German großkelchiges johanniskraut
German immergrünes johanniskraut
Esperanto grandflora hiperiko
Basque orkatx lore-handi
Persian ستاره اورشلیم
French millepertuis a grandes fleurs
French millepertuis à grandes fleurs
Upper Sorbian niski zahrodny křižomnik
Hungarian örökzöld orbáncfű
Hungarian bőrlevelű orbáncfű
Italian iperico calicino
Japanese セイヨウキンシバイ
Japanese ヒメキンシバイ
Dutch grootbladig hertshooi
Polish dziurawiec kielichowaty
Russian Зверобой чашечковидный
Russian Зверобой чашечный
Slovak Ľubovník kalíškatý
Swedish prakthyperikum
Chinese 冬绿金丝桃

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Australasia
    • Australia
      • Tasmania
    • New Zealand
      • New Zealand North
      • New Zealand South
  • Europe
    • Eastern Europe
      • Krym
    • Northern Europe
      • Great Britain
    • Southeastern Europe
      • Bulgaria
      • Greece
      • Italy
      • Turkey-in-Europe
      • Yugoslavia
    • Southwestern Europe
      • France

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000727444
Canadensys 29123
USDA Plants HYCA10
Tropicos 7800695
INPN 103254
Flora of Italy 1232
KEW urn:lsid:ipni.org:names:433287-1
The Plant List kew-2857855
Plantarium 20476
Missouri Botanical Garden 279207
Open Tree Of Life 974219
Observations.org 118884
NCBI Taxonomy 55963
NBN Atlas NBNSYS0000002956
Nature Serve 2.159739
IPNI 433287-1
iNaturalist 77481
GBIF 3189497
Freebase /m/02h4bp
EPPO HYPCA
EOL 584899
Elurikkus 374095
Calflora (Californian flora) 8602
USDA GRIN 19561
Wikipedia Hypericum_calycinum

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Which Plant Species for Green Roofs in the Mediterranean Environment? Leotta L, Toscano S, Romano D Plants (Basel) 27-Nov-2023
PMCID:PMC10708222
doi:10.3390/plants12233985
PMID:38068621
The most polyphagous insect herbivore? Host plant associations of the Meadow spittlebug, Philaenus spumarius (L.) Thompson V, Harkin C, Stewart AJ PLoS One 04-Oct-2023
PMCID:PMC10602594
doi:10.1371/journal.pone.0291734
PMID:37792900
Transcriptomic Analysis Reveals Novel Regulators of the Scots Pine Stilbene Pathway Paasela T, Lim KJ, Pavicic M, Harju A, Venäläinen M, Paulin L, Auvinen P, Kärkkäinen K, Teeri TH Plant Cell Physiol 09-Aug-2023
PMCID:PMC10579783
doi:10.1093/pcp/pcad089
PMID:37674261
Essential Oil Composition of Seven Bulgarian Hypericum Species and Its Potential as a Biopesticide Semerdjieva I, Zheljazkov VD, Dincheva I, Piperkova N, Maneva V, Cantrell CL, Astatkie T, Stoyanova A, Ivanova T Plants (Basel) 17-Feb-2023
PMCID:PMC9962312
doi:10.3390/plants12040923
PMID:36840272
Xanthones: Biosynthesis and Trafficking in Plants, Fungi and Lichens Badiali C, Petruccelli V, Brasili E, Pasqua G Plants (Basel) 04-Feb-2023
PMCID:PMC9967055
doi:10.3390/plants12040694
PMID:36840041
Eco-Evo-Devo of petal pigmentation patterning Fairnie AL, Yeo MT, Gatti S, Chan E, Travaglia V, Walker JF, Moyroud E Essays Biochem 08-Dec-2022
PMCID:PMC9750854
doi:10.1042/EBC20220051
PMID:36205404
Phytochemicals That Interfere With Drug Metabolism and Transport, Modifying Plasma Concentration in Humans and Animals Gómez-Garduño J, León-Rodríguez R, Alemón-Medina R, Pérez-Guillé BE, Soriano-Rosales RE, González-Ortiz A, Chávez-Pacheco JL, Solorio-López E, Fernandez-Pérez P, Rivera-Espinosa L Dose Response 21-Sep-2022
PMCID:PMC9500303
doi:10.1177/15593258221120485
PMID:36158743
Biochemical and structural insights of multifunctional flavin-dependent monooxygenase FlsO1-catalyzed unexpected xanthone formation Yang C, Zhang L, Zhang W, Huang C, Zhu Y, Jiang X, Liu W, Zhao M, De BC, Zhang C Nat Commun 14-Sep-2022
PMCID:PMC9474520
doi:10.1038/s41467-022-33131-0
PMID:36104338
Xanthone Biosynthetic Pathway in Plants: A Review Remali J, Sahidin I, Aizat WM Front Plant Sci 08-Apr-2022
PMCID:PMC9024401
doi:10.3389/fpls.2022.809497
PMID:35463410
Antioxidant, antifungal, and aphicidal activity of the triterpenoids spinasterol and 22,23-dihydrospinasterol from leaves of Citrullus colocynthis L. Ahmed M, Sajid AR, Javeed A, Aslam M, Ahsan T, Hussain D, Mateen A, Li X, Qin P, Ji M Sci Rep 22-Mar-2022
PMCID:PMC8940894
doi:10.1038/s41598-022-08999-z
PMID:35318417
Hypericum lanceolatum Lam. Medicinal Plant: Potential Toxicity and Therapeutic Effects Based on a Zebrafish Model Gence L, Fernezelian D, Bringart M, Veeren B, Christophe A, Brion F, Meilhac O, Bascands JL, Diotel N Front Pharmacol 11-Mar-2022
PMCID:PMC8963451
doi:10.3389/fphar.2022.832928
PMID:35359845
Aryl Coenzyme A Ligases, a Subfamily of the Adenylate-Forming Enzyme Superfamily Arnold ME, Kaplieva-Dudek I, Heker I, Meckenstock RU Appl Environ Microbiol 26-Aug-2021
PMCID:PMC8388817
doi:10.1128/AEM.00690-21
PMID:34260306
Characterization of a Cytosolic Acyl-Activating Enzyme Catalyzing the Formation of 4-Methylvaleryl-CoA for Pogostone Biosynthesis in Pogostemon Cablin Chen J, Liu L, Wang Y, Li Z, Wang G, Kraus GA, Pichersky E, Xu H Plant Cell Physiol 13-Jul-2021
PMCID:PMC8643619
doi:10.1093/pcp/pcab111
PMID:34255851
An Integrated—Omics/Chemistry Approach Unravels Enzymatic and Spontaneous Steps to Form Flavoalkaloidal Nudicaulin Pigments in Flowers of Papaver nudicaule L. Dudek B, Warskulat AC, Vogel H, Wielsch N, Menezes RC, Hupfer Y, Paetz C, Gebauer-Jung S, Svatoš A, Schneider B Int J Mol Sci 16-Apr-2021
PMCID:PMC8073789
doi:10.3390/ijms22084129
PMID:33923591
The Biochemical and Genetic Basis for the Biosynthesis of Bioactive Compounds in Hypericum perforatum L., One of the Largest Medicinal Crops in Europe Rizzo P, Altschmied L, Ravindran BM, Rutten T, D’Auria JC Genes (Basel) 16-Oct-2020
PMCID:PMC7602838
doi:10.3390/genes11101210
PMID:33081197

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Aromatic monoterpenoids
Hypercalin B 5281562 Click to see CC(=CCC1(C(=O)C(=C(C(=C(C2=CC=CC=C2)O)C1=O)O)CC3C(CCC3(C)O)C(=C)C)CC=C(C)C)C 518.70 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC61112/
https://doi.org/10.1002/HLCA.19890720820
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Bicyclic monoterpenoids
Hyperforin 441298 Click to see CC(C)C(=O)C12C(=O)C(=C(C(C1=O)(CC(C2(C)CCC=C(C)C)CC=C(C)C)CC=C(C)C)O)CC=C(C)C 536.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2004.10.020
https://doi.org/10.1016/J.PHYTOCHEM.2004.11.003
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Monocyclic monoterpenoids
(6R)-3,5-dihydroxy-4-[[(1S,2R,5R)-2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclopentyl]methyl]-6-methyl-2-[(2S)-2-methylbutanoyl]-6-(3-methylbut-2-enyl)cyclohexa-2,4-dien-1-one 10411215 Click to see CCC(C)C(=O)C1=C(C(=C(C(C1=O)(C)CC=C(C)C)O)CC2C(CCC2(C)O)C(=C)C)O 444.60 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC61112/
(6S)-3,5-dihydroxy-4-[[(1R,2S,5S)-2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclopentyl]methyl]-6-methyl-2-(3-methylbutanoyl)-6-(3-methylbut-2-enyl)cyclohexa-2,4-dien-1-one 162874309 Click to see CC(C)CC(=O)C1=C(C(=C(C(C1=O)(C)CC=C(C)C)O)CC2C(CCC2(C)O)C(=C)C)O 444.60 unknown https://doi.org/10.1002/HLCA.19890720820
(6S)-3,5-dihydroxy-4-[[(1R,2S,5S)-2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclopentyl]methyl]-6-methyl-6-(3-methylbut-2-enyl)-2-(2-methylpropanoyl)cyclohexa-2,4-dien-1-one 162989005 Click to see CC(C)C(=O)C1=C(C(=C(C(C1=O)(C)CC=C(C)C)O)CC2C(CCC2(C)O)C(=C)C)O 430.60 unknown https://doi.org/10.1002/HLCA.19890720820
3,5-Dihydroxy-4-[(2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclopentyl)methyl]-6-methyl-2-(3-methylbutanoyl)-6-(3-methylbut-2-enyl)cyclohexa-2,4-dien-1-one 360845 Click to see CC(C)CC(=O)C1=C(C(=C(C(C1=O)(C)CC=C(C)C)O)CC2C(CCC2(C)O)C(=C)C)O 444.60 unknown https://doi.org/10.1002/HLCA.19890720820
3,5-Dihydroxy-4-[(2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclopentyl)methyl]-6-methyl-6-(3-methylbut-2-enyl)-2-(2-methylpropanoyl)cyclohexa-2,4-dien-1-one 360846 Click to see CC(C)C(=O)C1=C(C(=C(C(C1=O)(C)CC=C(C)C)O)CC2C(CCC2(C)O)C(=C)C)O 430.60 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC61112/
https://doi.org/10.1002/HLCA.19890720820
3,5-Dihydroxy-4-[(2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclopentyl)methyl]-6,6-bis(3-methylbut-2-enyl)-2-(2-methylpropanoyl)cyclohexa-2,4-dien-1-one 14502639 Click to see CC(C)C(=O)C1=C(C(=C(C(C1=O)(CC=C(C)C)CC=C(C)C)O)CC2C(CCC2(C)O)C(=C)C)O 484.70 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC61112/
https://doi.org/10.1002/HLCA.19890720820
3,5-dihydroxy-4-[[(1R,2S,5S)-2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclopentyl]methyl]-6,6-bis(3-methylbut-2-enyl)-2-(2-methylpropanoyl)cyclohexa-2,4-dien-1-one 72944684 Click to see CC(C)C(=O)C1=C(C(=C(C(C1=O)(CC=C(C)C)CC=C(C)C)O)CC2C(CCC2(C)O)C(=C)C)O 484.70 unknown https://doi.org/10.1002/HLCA.19890720820
3,5-Dihydroxy-6-[(2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclopentyl)methyl]-2-(3-methylbutanoyl)-4-(3-methylbut-2-enyl)cyclohexa-2,4-dien-1-one 102195393 Click to see CC(C)CC(=O)C1=C(C(=C(C(C1=O)CC2C(CCC2(C)O)C(=C)C)O)CC=C(C)C)O 430.60 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC61112/
https://doi.org/10.1002/HLCA.19890720820
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glucuronides / Flavonoid-3-O-glucuronides
Quercetin 3-glucuronide 12004528 Click to see C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)C(=O)O)O)O)O)O)O 478.40 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC61112/

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