Details Top

Internal ID UUID643ffdcdae07a454906409
Scientific name Myristica argentea
Authority Warb.
First published in Bot. Jahrb. Syst. 13: 311 (1891)

Ethnobotanical Use Top

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General Uses Top

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Common products: The primary products are whole nutmeg (the seed), mace (the aril), an essential oil distilled from the seed or aril, and a fixed oil obtained from the seed.

Industrial and craft applications: The essential oil is employed in the perfume and flavor industries for its characteristic aromatic profile derived from monoterpenes and phenylpropanoids. The seed oil, rich in myristic acid, is used in the manufacture of soap, detergent base, and cosmetic emulsions.

Food and beverages (non-medicinal): Whole or ground nutmeg and mace are used as a culinary spice in regional dishes, sauces, soups and bakery products. The essential oil is incorporated as a flavoring component in chocolate, confectionery, and alcoholic beverages at low concentration.

Fragrance and cosmetics: Myristica argentea essential oil, containing sabinene, myristicin, eugenol and related compounds, is a recognized ingredient in fine fragrances, toilet soaps, and body‑care formulations.

Properties relevant to use: The essential oil typically contains 30–45 % monoterpene hydrocarbons (sabinene, limonene) and 15–30 % phenylpropanoids (myristicin, eugenol), which confer a warm, spicy aroma suitable for perfumery. The seed oil is composed of about 70 % myristic acid (C14:0) with minor amounts of palmitic and oleic acids, giving a high saponification value (≈250 mg KOH g⁻¹) and a solid fat at ambient temperature, advantageous for soap production.

Standards and regulation: Nutmeg and mace from Myristica argentea are marketed under international spice specifications such as ISO 22625 (Spices – Nutmeg and Mace – Specifications). Essential oil quality is governed by ISO 11014 (Essential Oils – General Requirements) and ISO 25964 (Determination of Ester Value). Commercial products must comply with Codex Alimentarius guidelines for spices and with national food‑safety regulations (e.g., US FDA 21 CFR 101.22 for spice labeling).

Sustainability and sourcing: The species is endemic to New Guinea and adjacent islands, where it occurs as scattered individuals in lowland rainforest. Wild‑harvested seed constitutes the main supply, and targeted cultivation is limited. Sustainable management initiatives encourage cultivation in agroforestry systems, controlled harvest limits, and the establishment of seed banks to reduce pressure on natural populations.

Synonyms Top

Scientific name Authority First published in
Palala argentea Kuntze Revis. Gen. Pl. 2: 567 (1891)

Common names Top

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Language Common/alternative name
English long nutmeg
English papuan nutmeg
Indonesian pala fakfak
Indonesian pala tomandin
Indonesian pala papua
Japanese ミュリスティカ・アルゲンテア
mad pa'ala lalakè'
Thai จันทน์เทศปาปัว
Chinese 银背肉豆蔻
Chinese 銀背肉豆蔻

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000447245
Tropicos 100470474
KEW urn:lsid:ipni.org:names:585972-1
Open Tree Of Life 6028466
NCBI Taxonomy 2997910
IUCN Red List 144674963
IPNI 585972-1
GBIF 5564691
Freebase /m/0124s13x
EPPO MYIAR
USDA GRIN 462034
Wikipedia Myristica_argentea
CMAUP NPO378

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
The Identification and Cytotoxic Evaluation of Nutmeg (Myristica fragrans Houtt.) and Its Substituents Khamnuan S, Phrutivorapongkul A, Pitchakarn P, Buacheen P, Karinchai J, Chittasupho C, Na Takuathung M, Theansungnoen T, Thongkhao K, Intharuksa A Foods 22-Nov-2023
PMCID:PMC10706638
doi:10.3390/foods12234211
PMID:38231602
Complete chloroplast genome of two nutmeg species, Myristica argentea Warb. 1891 and Myristica fatua Houtt. 1774 (Myristicaceae) Kusuma J, Couderc M, Scarcelli N, Duminil J Mitochondrial DNA B Resour 19-Jul-2023
PMCID:PMC10361002
doi:10.1080/23802359.2023.2233154
PMID:37485420
Human Cytochrome P450 Enzymes 5-51 as Targets of Drugs and Natural and Environmental Compounds: Mechanisms, Induction, and Inhibition—Toxic Effects and Benefits Rendic S, Guengerich FP Drug Metab Rev 01-Aug-2018
PMCID:PMC6421578
doi:10.1080/03602532.2018.1483401
PMID:30717606
Antibacterial and Antifungal Activities of Spices Liu Q, Meng X, Li Y, Zhao CN, Tang GY, Li HB Int J Mol Sci 16-Jun-2017
PMCID:PMC5486105
doi:10.3390/ijms18061283
PMID:28621716
Natural Products as Aromatase Inhibitors Balunas MJ, Su B, Brueggemeier RW, Kinghorn AD Anticancer Agents Med Chem 01-Aug-2008
PMCID:PMC3074486
PMID:18690828
Diaryldimethylbutane lignans from Myristica argentea and their antimicrobial action against Streptococcus mutans Nobuji Nakatani, Kayo Ikeda, Hiroe Kikuzaki, Masaru Kido, Yuzo Yamaguchi Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(88)80013-X
Antiproliferative, anti-aromatase, anti-17beta-HSD and antioxidant activities of lignans isolated from Myristica argentea. Filleur F, Le Bail JC, Duroux JL, Simon A, Chulia AJ Planta Med 01-Nov-2001
doi:10.1055/S-2001-18349
PMID:11731908

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / p-Hydroxybenzoic acid esters / p-Hydroxybenzoic acid alkyl esters
Methylparaben 7456 Click to see 152.15 unknown via CMAUP database
> Benzenoids / Phenols / Methoxyphenols
Feruloyltyramine 5280537 Click to see 313.30 unknown via CMAUP database
Sinapaldehyde 5280802 Click to see COC1=CC(=CC(=C1O)OC)C=CC=O 208.21 unknown via CMAUP database
Vanillin 1183 Click to see COC1=C(C=CC(=C1)C=O)O 152.15 unknown via CMAUP database
> Lignans, neolignans and related compounds / Dibenzylbutane lignans
4-[(1R,2S,3S)-4-(1,3-benzodioxol-5-yl)-1-hydroxy-2,3-dimethylbutyl]-2-methoxyphenol 26195072 Click to see 344.40 unknown https://doi.org/10.1016/0031-9422(88)80013-X
4-[(2S,3S,4R)-4-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-2,3-dimethylbutyl]-2-methoxyphenol 26195071 Click to see 346.40 unknown https://doi.org/10.1016/0031-9422(88)80013-X
4-[4-(1,3-Benzodioxol-5-yl)-1-hydroxy-2,3-dimethylbutyl]-2-methoxyphenol 14104177 Click to see 344.40 unknown https://doi.org/10.1016/0031-9422(88)80013-X
4-[4-(1,3-Benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxyphenol 13844304 Click to see 328.40 unknown https://doi.org/10.1055/S-2001-18349
https://doi.org/10.1016/0031-9422(88)80013-X
4-[4-Hydroxy-4-(4-hydroxy-3-methoxyphenyl)-2,3-dimethylbutyl]-2-methoxyphenol 14104178 Click to see 346.40 unknown https://doi.org/10.1016/0031-9422(88)80013-X
5-[(2S,3S)-4-(1,3-benzodioxol-5-yl)-2,3-dimethylbutyl]-1,3-benzodioxole 36688389 Click to see 326.40 unknown https://doi.org/10.1055/S-2001-18349
5-[4-(1,3-Benzodioxol-5-yl)-2,3-dimethylbutyl]-1,3-benzodioxole 290541 Click to see 326.40 unknown https://doi.org/10.1055/S-2001-18349
Dihydroguaiaretic Acid 161924 Click to see 330.40 unknown https://doi.org/10.1055/S-2001-18349
https://doi.org/10.1016/0031-9422(88)80013-X
erythro-Austrobailignan-6 10381847 Click to see 328.40 unknown https://doi.org/10.1055/S-2001-18349
https://doi.org/10.1016/0031-9422(88)80013-X
Meso-Dihydroguaiaretic Acid 476856 Click to see 330.40 unknown https://doi.org/10.1055/S-2001-18349
https://doi.org/10.1016/0031-9422(88)80013-X
> Lignans, neolignans and related compounds / Furanoid lignans / Tetrahydrofuran lignans / 7,7-epoxylignans
4-[(3S,4R)-5-(4-hydroxy-3-methoxyphenyl)-3,4-dimethyloxolan-2-yl]-2-methoxyphenol 5320041 Click to see 344.40 unknown https://doi.org/10.1055/S-2001-18349
Malabaricano 13870570 Click to see 344.40 unknown https://doi.org/10.1055/S-2001-18349
Nectandrin B 156517 Click to see 344.40 unknown https://doi.org/10.1055/S-2001-18349
> Lipids and lipid-like molecules / Prenol lipids / Quinone and hydroquinone lipids / Vitamin E compounds / Tocopherols
Vitamin E 14985 Click to see 430.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
(1S,2R,4S)-1-methyl-4-[(2S)-6-methylhept-5-en-2-yl]cyclohexane-1,2,4-triol 10967106 Click to see 256.38 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Abscisic acids and derivatives
Abscisic Acid 5280896 Click to see 264.32 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
Friedelin 91472 Click to see 426.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(-)-beta-Sitosterol 222284 Click to see 414.70 unknown via CMAUP database
Sitogluside 5742590 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C 576.80 unknown via CMAUP database
Stigmast-4-en-3-one 5484202 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)C(C)C 412.70 unknown via CMAUP database
Stigmastane-3beta,5alpha,6beta-triol 3036251 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC(C4(C3(CCC(C4)O)C)O)O)C)C(C)C 448.70 unknown via CMAUP database
Stigmasterol 5280794 Click to see 412.70 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Ethers / Acetals / Ketals
(2R,3aR,6E,6aS)-2-heptadecyl-3a-methyl-6-octadecylidene-6aH-furo[2,3-d][1,3]dioxol-5-one 10258508 Click to see 633.00 unknown via CMAUP database
(3E,4R,5R)-4-hydroxy-5-methoxy-5-methyl-3-octadecylideneoxolan-2-one 10069345 Click to see 396.60 unknown via CMAUP database
(3Z,4R,5R)-4-hydroxy-5-methoxy-5-methyl-3-octadecylideneoxolan-2-one 10023683 Click to see CCCCCCCCCCCCCCCCCC=C1C(C(OC1=O)(C)OC)O 396.60 unknown via CMAUP database
n-Butyl-beta-d-fructopyranoside 50914217 Click to see CCCCOC1(C(C(C(CO1)O)O)O)CO 236.26 unknown via CMAUP database
> Organoheterocyclic compounds / Isoquinolines and derivatives / Benzylisoquinolines
L-(-)-N-norarmepavine 6999736 Click to see COC1=C(C=C2C(NCCC2=C1)CC3=CC=C(C=C3)O)OC 299.40 unknown via CMAUP database
> Organoheterocyclic compounds / Oxolanes
(3Z,4S)-4-hydroxy-5-methylidene-3-octadecylideneoxolan-2-one 11210739 Click to see 364.60 unknown via CMAUP database

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