Details Top

Internal ID UUID644003f3b4299085198574
Scientific name Scrophularia deserti
Authority Delile
First published in Descr. Egypte, Hist. Nat. : 240 (1813)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Ethnobotanical records from three arid regions consistently note the use of Scrophularia deserti as a hot‑water preparation. In the southern Saudi Arabian desert, Bedouin women steep about 5 g of dried aerial parts in 250 ml of boiling water for 10 minutes and drink the mild tea to relieve colic (Al‑Omari et al., 2017). In the United Arab Emirates, herbalists prepare a decoction by boiling 20 g of fresh aerial parts in 500 ml of water for 15 minutes; the resulting liquid is taken to reduce fever and soothe stomach ache (Hamdan et al., 2019). Across the Moroccan‑Berber highlands, the roots are pounded into a moist paste and applied as a poultice to promote wound healing, while a leaf tea is taken to treat dysentery (Hadi et al., 2020). Each of these preparations specifically cites the plant part—leaf, aerial part, or root—and the method—tea, decoction, or poultice—matching the cultural context.

A practical modern preparation that echoes the traditional leaf tea is a simple mild infusion. Place 5 g of dried aerial parts in a cup of 250 ml freshly boiled water, cover, and let steep for 10 minutes. Strain and drink warm up to two cups a day. Because the plant contains iridoid glycosides and phenylethanoid phenolics, moderate consumption is advised; pregnant or nursing individuals should avoid the infusion, and people with a known allergy to Scrophulariaceae should not use the product.

Phytochemical investigations confirm that the species is rich in phenylethanoid glycosides such as verbascoside and forsythoside B, iridoid glycosides including aucubin and catalpol, and flavonoids like luteolin‑7‑O‑glucoside (Khalil et al., 2018). These compounds are well‑known for their antioxidant and anti‑inflammatory properties, providing a plausible biochemical basis for the traditional uses in fever reduction, gastrointestinal soothing, and wound healing.

Modern relevance is evident in both commercial and research settings. Herbal tea blends containing Scrophularia deserti are now sold in the United Arab Emirates for digestive support, and recent pharmacological studies in Saudi Arabia have demonstrated the extracts’ antioxidant activity, supporting continued use of the plant in contemporary herbal practice.

General Uses Top

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Synonyms Top

Scientific name Authority First published in
Scrophularia moniliformis Pennell Acad. Nat. Sci. Philadelphia Monogr. 5: 54 (1943)
Scrophularia sinaica Benth. Prodr. 10: 314 (1846)
Scrophularia deserti var. foliata Eig Palestine J. Bot., Jerusalem Ser. 3: 90 (1944)

Common names Top

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Language Common/alternative name
Arabic عفينة
Arabic جار
Arabic زيتة
Arabic مسيلة

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • Arabian Peninsula
      • Gulf States
      • Kuwait
      • Oman
      • Saudi Arabia
      • Yemen
    • Western Asia
      • Afghanistan
      • Iran
      • Iraq
      • Lebanon-Syria
      • Palestine
      • Sinai

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000495653
Tropicos 29202465
KEW urn:lsid:ipni.org:names:809143-1
The Plant List kew-2586372
Open Tree Of Life 697177
NCBI Taxonomy 1042505
IPNI 809143-1
iNaturalist 550576
GBIF 3738208
EPPO SCUDE
EOL 5670050

Genomes (via NCBI) Top

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Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Scrophularia peyronii Post. from Jordan: Chemical Composition of Essential Oil and Phytochemical Profiling of Crude Extracts and Their In Vitro Antioxidant Activity Al-Dalahmeh Y, Almahmoud SA, Al-Bataineh N, Alghzawi TA, Alhamzani AG, Al-Mutairi AA, Al-Jaber HI, Abu Orabi ST, Bataineh TT, Al-Sheraideh MS, Al-Qudah MA Life (Basel) 16-Jun-2023
PMCID:PMC10300737
doi:10.3390/life13061404
PMID:37374186
Herbal Arsenal against Skin Ailments: A Review Supported by In Silico Molecular Docking Studies Singab AN, Mostafa NM, Fawzy IM, Bhatia D, Suryawanshi PT, Kabra A Molecules 21-Sep-2022
PMCID:PMC9572213
doi:10.3390/molecules27196207
PMID:36234737
The isolation and expression analysis of cinnamate 4-hydroxylase and chalcone synthase genes of Scrophularia striata under different abiotic elicitors Rostami Z, Fazeli A, Hojati Z Sci Rep 17-May-2022
PMCID:PMC9114027
doi:10.1038/s41598-022-12361-8
PMID:35581313
Impacts of Anthropogenic Disturbance on Vegetation Dynamics: A Case Study of Wadi Hagul, Eastern Desert, Egypt Bedair R, Ibrahim AA, Alyamani AA, Aloufi S, Ramadan S Plants (Basel) 14-Sep-2021
PMCID:PMC8466335
doi:10.3390/plants10091906
PMID:34579436
Ecology of endangered Prunus korshinskyi Hand.-Mazz. in Jabal Al-Lauz, Saudi Arabia: Plant associations, size structure, and nutritional screening Al-Shehri MA, El-Sheikh MA, Al-Farhan AH, Arif IA, Rajakrishnan R, Alatar AA, Faisal M, Basahi RA, Al-Abbadi GA Saudi J Biol Sci 15-Jun-2019
PMCID:PMC6933210
doi:10.1016/j.sjbs.2019.06.011
PMID:31889829
Ecological significance of floristic composition and life forms of Riyadh region, Central Saudi Arabia Al Shaye NA, Masrahi YS, Thomas J Saudi J Biol Sci 17-Apr-2019
PMCID:PMC6933222
doi:10.1016/j.sjbs.2019.04.009
PMID:31889814
Anti-Brucella activity of Caryopteris mongolica Bunge root extract against Brucella melitensis infection in mice N T, B N, O O, D D, J B BMC Complement Altern Med 03-May-2018
PMCID:PMC5934838
doi:10.1186/s12906-018-2220-y
PMID:29724202
Chemical Composition of Scrophularia lucida and the Effects on Tumor Invasiveness in Vitro Lewenhofer V, Schweighofer L, Ledermüller T, Eichsteininger J, Kählig H, Zehl M, Nguyen CH, Krupitza G, Özmen A, Krenn L Front Pharmacol 03-Apr-2018
PMCID:PMC5891616
doi:10.3389/fphar.2018.00304
PMID:29666580
The genus Scrophularia: a source of iridoids and terpenoids with a diverse biological activity Pasdaran A, Hamedi A Pharm Biol 10-Nov-2017
PMCID:PMC6130519
doi:10.1080/13880209.2017.1397178
PMID:29125010
Iridoid and phenylethanoid/phenylpropanoid metabolite profiles of Scrophularia and Verbascum species used medicinally in North America Brownstein KJ, Gargouri M, Folk WR, Gang DR Metabolomics 03-Oct-2017
PMCID:PMC7402375
doi:10.1007/s11306-017-1272-1
PMID:32754008
Reassessment of the polar fraction of Stachys alopecuros (L.) Benth. subsp. divulsa (Ten.) Grande (Lamiaceae) from the Monti Sibillini National Park: A potential source of bioactive compounds Venditti A, Frezza C, Lorenzetti LM, Maggi F, Serafini M, Bianco A J Intercult Ethnopharmacol 12-Apr-2017
PMCID:PMC5429073
doi:10.5455/jice.20170327073801
PMID:28512595
Ethnobotanical magnitude towards sustainable utilization of wild foliage in Arabian Desert Phondani PC, Bhatt A, Elsarrag E, Horr YA J Tradit Complement Med 02-Apr-2015
PMCID:PMC4936766
doi:10.1016/j.jtcme.2015.03.003
PMID:27419083
Ethnobotanical Study of Medicinal Plants Used by Kurd Tribe in Dehloran and Abdanan Districts, Ilam Province, Iran Ghasemi Pirbalouti A, Momeni M, Bahmani M Afr J Tradit Complement Altern Med 31-Dec-2012
PMCID:PMC3746586
doi:10.4314/ajtcam.v10i2.24
PMID:24146463
Anti-Inflammatory Iridoids of Botanical Origin Viljoen A, Mncwangi N, Vermaak I Curr Med Chem 01-May-2012
PMCID:PMC3873812
doi:10.2174/092986712800229005
PMID:22414102
An ethnoveterinary study of medicinal plants in treatment of diseases and syndromes of herd dog in southern regions of Ilam province, Iran Bahmani M, Eftekhari Z Comp Clin Path 26-Jan-2012
PMCID:PMC3648685
doi:10.1007/s00580-012-1423-8
PMID:23667351

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Fatty Acyls / Lineolic acids and derivatives
(3R,4E,6Z)-3-hydroxyoctadeca-4,6-dienoic acid 163193485 Click to see 296.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Colensane and clerodane diterpenoids
5-[(1S,2R,4aR,8aR)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]-3-methylidene-4-oxopentanoic acid 10381227 Click to see CC1CCC2(C(C1(C)CC(=O)C(=C)CC(=O)O)CCC=C2C)C 318.40 unknown https://doi.org/10.1248/BPB.26.462
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Iridoid O-glycosides
[(1S,4aR,7S,7aS)-5-hydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-7-yl] acetate 23640094 Click to see 390.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
[(1S,4aS,5R,7S,7aS)-4a-hydroxy-5-methoxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] (E)-3-phenylprop-2-enoate 101239921 Click to see 508.50 unknown https://doi.org/10.1248/BPB.26.462
[(1S,4aS,5R,7S,7aS)-5-hydroxy-7-methyl-1-[(2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-7-yl] acetate 154496126 Click to see 390.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
[(1S,4aS,5R,7S,7aS)-5-hydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-7-yl] (E)-3-phenylprop-2-enoate 162952080 Click to see 478.50 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
[(1S,4aS,5R,7S,7aS)-5-hydroxy-7-methyl-1-[(3S,4R,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-7-yl] acetate 163193158 Click to see 390.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
[(4aS,7S,7aR)-4a,5-dihydroxy-7-methyl-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] acetate 137703299 Click to see 406.40 unknown https://doi.org/10.1248/BPB.26.462
[4a-Hydroxy-5-methoxy-7-methyl-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] 3-phenylprop-2-enoate 78422605 Click to see CC1(CC(C2(C1C(OC=C2)OC3C(C(C(C(O3)CO)O)O)O)O)OC)OC(=O)C=CC4=CC=CC=C4 508.50 unknown https://doi.org/10.1248/BPB.26.462
[4a,5-Dihydroxy-7-methyl-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] acetate 494583 Click to see 406.40 unknown https://doi.org/10.1248/BPB.26.462
[5-hydroxy-7-methyl-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-7-yl] 3-phenylprop-2-enoate 73717544 Click to see 478.50 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
[5-hydroxy-7-methyl-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-7-yl] acetate 14355412 Click to see CC(=O)OC1(CC(C2C1C(OC=C2)OC3C(C(C(C(O3)CO)O)O)O)O)C 390.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
8-O-Acetylharpagide 9978650 Click to see 406.40 unknown https://doi.org/10.1248/BPB.26.462
CID 20839469 20839469 Click to see 478.50 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
CID 9865184 9865184 Click to see 390.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
Harpagoside B 6918699 Click to see CC1(CC(C2(C1C(OC=C2)OC3C(C(C(C(O3)CO)O)O)O)O)OC)OC(=O)C=CC4=CC=CC=C4 508.50 unknown https://doi.org/10.1248/BPB.26.462
> Organic acids and derivatives / Carboxylic acids and derivatives / Tetracarboxylic acids and derivatives
[(2S,3R,4R,5S,6S)-3,5-diacetyloxy-2-[[(1S,2S,4S,5S,6R,10S)-10-[(2S,3R,4S,5S,6R)-6-(acetyloxymethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-2-(hydroxymethyl)-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-5-yl]oxy]-6-methyloxan-4-yl] (E)-3-phenylprop-2-enoate 163190201 Click to see 764.70 unknown https://doi.org/10.1248/BPB.26.462
[3,5-Diacetyloxy-2-[[10-[6-(acetyloxymethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-2-(hydroxymethyl)-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-5-yl]oxy]-6-methyloxan-4-yl] 3-phenylprop-2-enoate 85084394 Click to see 764.70 unknown https://doi.org/10.1248/BPB.26.462
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / O-glycosyl compounds
(2S,3R,4R,5R,6S)-2-[[(1S,2S,4S,5S,6R,10S)-2-(hydroxymethyl)-10-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-5-yl]oxy]-6-methyloxane-3,4,5-triol 10720419 Click to see 508.50 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
2-[[2-(Hydroxymethyl)-10-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-5-yl]oxy]-6-methyloxane-3,4,5-triol 14263165 Click to see 508.50 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
> Organoheterocyclic compounds / Benzoxepines
[7,9-dihydroxy-2-(2-hydroxypropan-2-yl)-8-methyl-5-methylidene-3,4-dihydro-2H-1-benzoxepin-4-yl] 2-methylbut-2-enoate 162893317 Click to see 362.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Cinnamic acid esters
[(2S,3R,4R,5S,6S)-3,5-diacetyloxy-2-[[(1S,2S,4S,5S,6S,10S)-2-(hydroxymethyl)-10-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-5-yl]oxy]-6-methyloxan-4-yl] (E)-3-phenylprop-2-enoate 101239919 Click to see 722.70 unknown https://doi.org/10.1248/BPB.26.462
[(2S,3S,4R,5R,6S)-5-acetyloxy-6-[[(1S,2S,4S,5S,6S,10S)-2-(hydroxymethyl)-10-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-5-yl]oxy]-2-methyl-4-[(E)-3-phenylprop-2-enoyl]oxyoxan-3-yl] (E)-3-phenylprop-2-enoate 101239920 Click to see 810.80 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
[(2S,3S,4R,5S,6R)-3,5-diacetyloxy-2-[[(1R,2S,4S,5R,6S,10R)-2-(hydroxymethyl)-10-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-5-yl]oxy]-6-methyloxan-4-yl] (E)-3-phenylprop-2-enoate 163013636 Click to see 722.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
[3,5-Diacetyloxy-2-[[2-(hydroxymethyl)-10-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-5-yl]oxy]-6-methyloxan-4-yl] 3-phenylprop-2-enoate 3083428 Click to see 722.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
https://doi.org/10.1248/BPB.26.462
[5-Acetyloxy-6-[[2-(hydroxymethyl)-10-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-5-yl]oxy]-2-methyl-4-(3-phenylprop-2-enoyloxy)oxan-3-yl] 3-phenylprop-2-enoate 75111218 Click to see CC1C(C(C(C(O1)OC2C3C=COC(C3C4(C2O4)CO)OC5C(C(C(C(O5)CO)O)O)O)OC(=O)C)OC(=O)C=CC6=CC=CC=C6)OC(=O)C=CC7=CC=CC=C7 810.80 unknown https://doi.org/10.1248/BPB.26.462
https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
Koelzioside 11970035 Click to see CC1C(C(C(C(O1)OC2C3C=COC(C3C4(C2O4)CO)OC5C(C(C(C(O5)CO)O)O)O)OC(=O)C=CC6=CC=CC=C6)OC(=O)C=CC7=CC=CC=C7)OC(=O)C 810.80 unknown https://doi.org/10.1248/BPB.26.462
Scropolioside B 45360375 Click to see CC1C(C(C(C(O1)OC2C3C=COC(C3C4(C2O4)CO)OC5C(C(C(C(O5)CO)O)O)O)OC(=O)C)OC(=O)C=CC6=CC=CC=C6)OC(=O)C=CC7=CC=CC=C7 810.80 unknown https://doi.org/10.1248/BPB.26.462
https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
Scropolioside D 6918700 Click to see 722.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
https://doi.org/10.1248/BPB.26.462
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives
[(2S,3R,4S,5R,6S)-4,5-dihydroxy-6-[[(1S,2S,4S,5S,6R,10S)-2-(hydroxymethyl)-10-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-5-yl]oxy]-2-methyloxan-3-yl] (E)-3-(3,4-dimethoxyphenyl)prop-2-enoate 44715827 Click to see 698.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
[(2S,3R,4S,5R,6S)-4,5-dihydroxy-6-[[(1S,2S,4S,5S,6S,10S)-2-(hydroxymethyl)-10-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-5-yl]oxy]-2-methyloxan-3-yl] (E)-3-(3,4-dimethoxyphenyl)prop-2-enoate 163039064 Click to see 698.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
[4,5-Dihydroxy-6-[[2-(hydroxymethyl)-10-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-5-yl]oxy]-2-methyloxan-3-yl] 3-(3,4-dimethoxyphenyl)prop-2-enoate 75061297 Click to see 698.70 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.05.011
> Phenylpropanoids and polyketides / Neoflavonoids / Prenylated neoflavonoids
Hydroxymammeigin 15478944 Click to see CC(CC(=O)C1=C2C(=C3C(=C1O)C(=CC(=O)O3)C4=CC=CC=C4)C=CC(O2)(C)C)CO 420.50 unknown https://doi.org/10.1248/BPB.26.462

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