Salvia pachyphylla in Genus Salvia

Details Top

Internal ID	UUID643febd73e907769079106
Scientific name	Salvia pachyphylla
Authority	Epling ex Munz
First published in	Man. S. Calif. Bot. : 600 (1935)

Description Top

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Salvia pachyphylla, also known as Blue sage or Mountain desert sage, is a perennial shrub found in California, Nevada, and Arizona. It grows at high elevations on dry rocky slopes and blooms from July to September. This plant reaches a height of 1 to 2 feet and has blue-violet flowers, with some rare instances of rose-colored flowers. A recent study by Ivan C. Guerrero and colleagues focused on the chemical composition of Salvia pachyphylla and Salvia clevelandii, both used in traditional Latin American medicine. The researchers isolated and tested the secondary metabolites from these plants and found that eight of them had cytotoxic effects on five different types of human cancer cells. These compounds include carnosol, rosmanol, carnosic acid, and pachyphyllone.

Synonyms Top

Scientific name	Authority	First published in
Ramona pachystachya	A.Heller	Muhlenbergia 1: 4. 1900
Audibertia incana var. pachystachya	A.Gray	Syn. Fl. N. Amer. 2(1): 461 (1886)
Audibertia pachystachya	Parish	Erythea 6: 91 (1898)
Salvia carnosa var. compacta	H.M.Hall	Univ. Calif. Publ. Bot. 1: 111 (1902)
Salvia compacta	Munz	Bull. S. Calif. Acad. Sci. 26: 22. 1927

Common names Top

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Language	Common/alternative name
English	blue sage

Subspecies (abbr. subsp./ssp.) Top

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Name	Authority	First published in
Salvia pachyphylla subsp. eremopictus	R.M.Taylor	Madroño 53: 21 (2006)
Salvia pachyphylla subsp. meridionalis	R.M.Taylor	Madroño 53: 22 (2006)
Salvia pachyphylla subsp. pachyphylla		Unknown

Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:

- Doubtful data

- Extinct

- Introduced

- Native

Northern America click to expand
- Mexico
  - Mexico Northwest
- Southwestern U.S.A.
  - Arizona
  - California
  - Nevada

Links to other databases Top

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Database	ID/link to page
World Flora Online	wfo-0000301825
USDA Plants	SAPA5
Tropicos	17601718
KEW	urn:lsid:ipni.org:names:289829-2
The Plant List	kew-183412
Open Tree Of Life	1061909
NCBI Taxonomy	207759
Nature Serve	2.148437
IPNI	289829-2
iNaturalist	78972
GBIF	2927034
Freebase	/m/0bs0qc7
EOL	578480
Calflora (Californian flora)	7314
USDA GRIN	32952
Wikipedia	Salvia_pachyphylla
CMAUP	NPO20067

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.

Title

Authors

Publication

Released

IDs

An Integrated Approach of Bioassays and Non-Target Screening for the Assessment of Endocrine-Disrupting Activities in Tap Water and Identification of Novel Endocrine-Disrupting Chemicals

Liu S, Liu J

Toxics

28-Mar-2024

PMCID:	PMC11054029
doi:	10.3390/toxics12040247
PMID:	38668470

Carnosol Alleviates Collagen-Induced Arthritis by Inhibiting Th17-Mediated Immunity and Favoring Suppressive Activity of Regulatory T Cells

Chen J, Sun N, Li F, Li H, Tian J, Zheng S, Zhang L, Wang H, Luo Y

Biomed Res Int

28-Jun-2023

PMCID:	PMC10322527
doi:	10.1155/2023/1179973
PMID:	37415927

Natural Products as Novel Neuroprotective Agents; Computational Predictions of the Molecular Targets, ADME Properties, and Safety Profile

Alghamdi SS, Suliman RS, Aljammaz NA, Kahtani KM, Aljatli DA, Albadrani GM

Plants (Basel)

18-Feb-2022

PMCID:	PMC8878483
doi:	10.3390/plants11040549
PMID:	35214883

Terpenoids as Potential Geroprotectors

Proshkina E, Plyusnin S, Babak T, Lashmanova E, Maganova F, Koval L, Platonova E, Shaposhnikov M, Moskalev A

Antioxidants (Basel)

17-Jun-2020

PMCID:	PMC7346221
doi:	10.3390/antiox9060529
PMID:	32560451

Reversal of Epithelial–Mesenchymal Transition by Natural Anti-Inflammatory and Pro-Resolving Lipids

Lee CH

Cancers (Basel)

21-Nov-2019

PMCID:	PMC6966475
doi:	10.3390/cancers11121841
PMID:	31766574

Biological Activities of Extracts from Aerial Parts of Salvia pachyphylla Epling Ex Munz

Almada-Taylor G, Díaz-Rubio L, Salazar-Aranda R, Waksman de Torres N, Uranga-Solis C, Delgadillo-Rodríguez J, Ramos MA, Padrón JM, Hernández-Martínez R, Córdova-Guerrero I

Plants (Basel)

23-Nov-2018

PMCID:	PMC6314080
doi:	10.3390/plants7040105
PMID:	30477162

Abietane diterpenoids from Salvia pachyphylla and S. clevelandii with cytotoxic activity against human cancer cell lines.

Guerrero IC, Andrés LS, León LG, Machín RP, Padrón JM, Luis JG, Delgadillo J

J Nat Prod

01-Dec-2006

doi:	10.1021/NP060279I
PMID:	17190465

Staminal Evolution in the Genus Salvia (Lamiaceae): Molecular Phylogenetic Evidence for Multiple Origins of the Staminal Lever

Walker JB, Sytsma KJ

Ann Bot

22-Aug-2006

PMCID:	PMC2735309
doi:	10.1093/aob/mcl176
PMID:	16926227

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name	PubChem ID	Canonical SMILES	MW	Found in	Proof
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids
(1R,8R,9S,10S)-3,4,8-trihydroxy-11,11-dimethyl-5-propan-2-yltetracyclo[7.5.2.01,10.02,7]hexadeca-2,4,6-trien-15-one	125181923	Click to see CC(C)C1=C(C(=C2C(=C1)C(C3CC(=O)C24C3C(CCC4)(C)C)O)O)O	344.40	unknown	https://doi.org/10.1021/NP060279I
(4aS)-6-methoxy-1,1,4a-trimethyl-7-propan-2-yl-3,4-dihydro-2H-phenanthren-9-one	11312990	Click to see CC(C)C1=C(C=C2C(=C1)C(=O)C=C3C2(CCCC3(C)C)C)OC	312.40	unknown	https://doi.org/10.1021/NP060279I
(4bS,8aS)-4b,8,8-trimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthrene-3,4-dione	15241261	Click to see CC(C)C1=CC2=C(C(=O)C1=O)C3(CCCC(C3CC2)(C)C)C	300.40	unknown	https://doi.org/10.1021/NP060279I
20-Deoxocarnosol	13855851	Click to see CC(C)C1=C(C(=C2C(=C1)C3CC4C2(CCCC4(C)C)CO3)O)O	316.40	unknown	https://doi.org/10.1021/NP060279I
8-Hydroxyabieta-9(11),13-diene-12-one	44427460	Click to see CC(C)C1=CC2(CCC3C(CCCC3(C2=CC1=O)C)(C)C)O	302.50	unknown	https://doi.org/10.1021/NP060279I
Carnosic acid	65126	Click to see CC(C)C1=C(C(=C2C(=C1)CCC3C2(CCCC3(C)C)C(=O)O)O)O	332.40	unknown	https://doi.org/10.1021/NP060279I
Pachyphyllone	44566415	Click to see CC(C)C1=CC23CCC4C(CCCC4(C2=C(C1=O)O)CO3)(C)C	316.40	unknown	via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones / Diterpene lactones
(1R,8S,9S)-3,4,8-trihydroxy-11,11-dimethyl-5-propan-2-yl-16-oxatetracyclo[7.5.2.01,10.02,7]hexadeca-2,4,6-trien-15-one	455261	Click to see CC(C)C1=C(C(=C2C(=C1)C(C3C4C2(CCCC4(C)C)C(=O)O3)O)O)O	346.40	unknown	https://doi.org/10.1021/NP060279I
(1S,8S,10S)-3,4-dihydroxy-8-methoxy-11,11-dimethyl-5-propan-2-yl-16-oxatetracyclo[7.5.2.01,10.02,7]hexadeca-2,4,6-trien-15-one	163194676	Click to see CC(C)C1=C(C(=C2C(=C1)C(C3C4C2(CCCC4(C)C)C(=O)O3)OC)O)O	360.40	unknown	https://doi.org/10.1021/NP060279I
(1S,8S,9S,10S)-3,4-dihydroxy-8-methoxy-11,11-dimethyl-5-propan-2-yl-16-oxatetracyclo[7.5.2.01,10.02,7]hexadeca-2,4,6-trien-15-one	163049544	Click to see CC(C)C1=C(C(=C2C(=C1)C(C3C4C2(CCCC4(C)C)C(=O)O3)OC)O)O	360.40	unknown	https://doi.org/10.1021/NP060279I
16-Hydroxycarnosol	44566424	Click to see CC(CO)C1=C(C(=C2C(=C1)C3CC4C2(CCCC4(C)C)C(=O)O3)O)O	346.40	unknown	via CMAUP database
Carnosol	442009	Click to see CC(C)C1=C(C(=C2C(=C1)C3CC4C2(CCCC4(C)C)C(=O)O3)O)O	330.40	unknown	via CMAUP database
Isorosmanol	13820511	Click to see CC(C)C1=C(C(=C2C(=C1)C3C(C4C2(CCCC4(C)C)C(=O)O3)O)O)O	346.40	unknown	https://doi.org/10.1021/NP060279I
> Organoheterocyclic compounds / Benzofurans
Rosmadial	15801061	Click to see CC(C)C1=C(C2=C(C(=C1)C=O)C3(CCCC(C3C=O)(C)C)C(=O)O2)O	344.40	unknown	via CMAUP database

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Salvia pachyphylla

Table of Contents

Details Top

Description Top

Synonyms Top

Common names Top

Subspecies (abbr. subsp./ssp.) Top

Varieties (abbr. var.) Top

Subvarieties (abbr. subvar.) Top

Forms (abbr. f.) Top

Germination/Propagation Top

Distribution (via POWO/KEW) Top

Links to other databases Top

Genomes (via NCBI) Top

Scientific Literature Top

Phytochemical Profile Top

Biological Material Top

Contributors Top

Collections Top