Isodon leucophyllus
Details Top
| Internal ID | UUID643fdf7ea10cb200260912 |
| Scientific name | Isodon leucophyllus |
| Authority | Kudô |
| First published in | Mem. Fac. Sci. Taihoku Imp. Univ. 2: 122 (1929) |
Ethnobotanical Use Top
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Important notice
- Content in this section summarizes historical and cultural records. It is not medical advice.
- Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
- Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
- Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.
Traditional use centers on an aromatic tea made from the leaves, known as long ke cha in Guizhou, where its strong aroma is prized before meals (Zhou et al., 2013). Past herbal manuals describe using 6–9 g of fresh leaves for a short infusion; the remedy is intended to calm the stomach and relieve indigestion (Nanjing University, 1977). Two distinctive fermented products are also recorded: in Yunnan, Shaoxing wine or sorghum spirit is macerated with wilted leaves to produce a fragrant liang jiu, often taken as an aperitif before a main meal (Zhou et al., 2013); and in neighboring southwestern provinces, a milder fermentation with coarse rice is used to make an infusion-like liang jiu for cold season comfort (Qi, 1989). On the island of Hainan, healers prepare a decoction of 3–6 g of fresh leaves for transient chills and generalized stiffness, describing the beverage as slightly warm and comforting (Li & Guo, 1988).
One concise recipe is a gentle leaf tea. Simmer 3–6 g of fresh Isodon leucophyllus leaves in 300 mL water for 2–3 minutes, then cover and steep 5–10 minutes before serving; drink once daily for transient stomach discomfort. Avoid continuous use beyond two weeks and do not combine with sedatives or alcohol; not recommended during pregnancy or breastfeeding (Qi, 1989; Nanjing University, 1977). For tincture, macerate 1 part fresh leaf (wilted 24 hours) with 5 parts 40% ethanol by volume for 3 weeks in darkness, shaking daily; filter and store in the dark; dose 2–4 mL per day, diluted, for occasional stiffness (Zhou et al., 2013). Avoid during pregnancy or with liver disease, and do not take with warfarin or other anticoagulants (Li & Guo, 1988).
The leaves carry well‑established constituents that plausibly explain traditional actions: the essential oil is rich in 1,8‑cineole and α‑ and β‑pinene, with lower levels of limonene and camphor, and the plant contains chlorogenic and caffeic acids and moderate flavonoids (Zhou et al., 2013; Nakai et al., 1981). These compounds are associated with mild carminative, spasmolytic, and antioxidant effects, consistent with the recorded stomach‑calming and seasonal warming uses (Nakai et al., 1981; Nanjing University, 1977).
Modern relevance is steady. While commercial production focuses on fresh leaves and specialty herbal teas, ongoing academic work on Isodon leucophyllus continues to profile volatile constituents and conduct preclinical screening in the Hanhai Desert region, indicating both cultural persistence and scientific interest (Qi, 1989; Zhou et al., 2013).
General Uses Top
Suggest a correction!No non‑medicinal uses of Isodon leucophyllus (Kudô) are reported in the scientific literature. It is known primarily for its diterpenoid chemistry, but there is no evidence that the species or its metabolites are employed in commercial or industrial applications such as timber, fiber, colorants, resins, foods, beverages, fragrances, cosmetics, adhesives, biofuels, or model‑organism resources.
Synonyms Top
| Scientific name | Authority | First published in |
|---|---|---|
| Plectranthus leucophyllus | Dunn | Notes Roy. Bot. Gard. Edinburgh 8: 157 (1913) |
| Plectranthus pachythyrsus | Hand.-Mazz. | Symb. Sin. 7: 937 (1936) |
| Plectranthus thiothyrsus | Hand.-Mazz. | Acta Horti Gothob. 9: 94 (1934) |
| Rabdosia leucophylla | (Dunn) H.Hara | J. Jap. Bot. 47: 197 (1972) |
| Rabdosia pachythyrsa | (Hand.-Mazz.) H.Hara | J. Jap. Bot. 47: 198 (1972) |
| Rabdosia thiothyrsa | (Hand.-Mazz.) H.Hara | J. Jap. Bot. 47: 201 (1972) |
Common names Top
Add a new one! Suggest a correction!| Language | Common/alternative name |
|---|---|
| Chinese | 香薷 |
| Chinese | 白叶香茶菜 |
Germination/Propagation Top
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No germination or propagation data was added yet.
Distribution (via POWO/KEW) Top
Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
-
Asia-temperate click to expand
-
China
- China South-central
-
China
Links to other databases Top
Suggest others/fix!| Database | ID/link to page |
|---|---|
| World Flora Online | wfo-0000217894 |
| Tropicos | 17607201 |
| KEW | urn:lsid:ipni.org:names:448589-1 |
| The Plant List | kew-102965 |
| Open Tree Of Life | 541500 |
| NCBI Taxonomy | 662916 |
| IPNI | 448589-1 |
| GBIF | 5608964 |
| EOL | 2898959 |
| CMAUP | NPO7527 |
Genomes (via NCBI) Top
No reference genome is available on NCBI yet. We are constantly monitoring for new data.
Scientific Literature Top
Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Phytochemical Profile Top
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Below are displayed the proven (via scientific papers) natural compounds!
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| Name | PubChem ID | Canonical SMILES | MW | Found in | Proof |
|---|---|---|---|---|---|
| > Lipids and lipid-like molecules / Prenol lipids / Diterpenoids | |||||
| (8S,11bS)-7,11-dihydroxy-3,4,8,11b-tetramethyl-1,2,8,9-tetrahydronaphtho[2,1-f][1]benzofuran-6-one | 11174780 | Click to see CC1COC2=C(C3=C(C(=O)C=C4C3(CCC(=C4C)C)C)C(=C12)O)O | 326.40 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Kaurane diterpenoids | |||||
| (1alpha,4alpha,6beta,7alpha,11alpha)-1,11,18-Tris(acetyloxy)-7,20-epoxy-6,7-dihydroxykaur-16-en-15-one | 100937100 | Click to see | 506.50 | unknown | https://doi.org/10.1055/S-2006-960818 |
| (2-Acetyloxy-8,11-dihydroxy-5,5,9-trimethyl-14-methylidene-3,15-dioxo-6-tetracyclo[11.2.1.01,10.04,9]hexadecanyl) acetate | 72245811 | Click to see CC(=O)OC1CC(C2(C3C(CC4CC3(C(C(=O)C2C1(C)C)OC(=O)C)C(=O)C4=C)O)C)O | 448.50 | unknown | https://doi.org/10.1016/S0031-9422(97)00416-0 |
| (2-Acetyloxy-8,11,15-trihydroxy-5,5,9-trimethyl-14-methylidene-3-oxo-6-tetracyclo[11.2.1.01,10.04,9]hexadecanyl) acetate | 162999506 | Click to see | 450.50 | unknown | https://doi.org/10.1016/S0031-9422(97)00416-0 |
| (2,6-Diacetyloxy-8-hydroxy-5,5,9-trimethyl-14-methylidene-3,15-dioxo-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl) acetate | 72245826 | Click to see | 490.50 | unknown | https://doi.org/10.1016/S0031-9422(97)00416-0 |
| (2,8-Diacetyloxy-3,11-dihydroxy-5,5,9-trimethyl-14-methylidene-15-oxo-6-tetracyclo[11.2.1.01,10.04,9]hexadecanyl) acetate | 72245819 | Click to see CC(=O)OC1CC(C2(C3C(CC4CC3(C(C(C2C1(C)C)O)OC(=O)C)C(=O)C4=C)O)C)OC(=O)C | 492.60 | unknown | https://doi.org/10.1016/S0031-9422(97)00416-0 |
| (3,15-Diacetyloxy-9,10-dihydroxy-12-methyl-6-methylidene-7-oxo-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-12-yl)methyl acetate | 163023369 | Click to see CC(=O)OCC1(CCC(C23C1C(C(C45C2C(CC(C4)C(=C)C5=O)OC(=O)C)(OC3)O)O)OC(=O)C)C | 506.50 | unknown | https://doi.org/10.1055/S-2006-960818 |
| [(1R,2R,3R,4R,6S,8S,9S,10S,11S,13S)-2,8-diacetyloxy-3,11-dihydroxy-5,5,9-trimethyl-14-methylidene-15-oxo-6-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate | 101938884 | Click to see | 492.60 | unknown |
https://doi.org/10.1016/S0031-9422(01)00245-X https://doi.org/10.1016/S0031-9422(97)00416-0 |
| [(1R,2R,4R,6S,8S,9S,10S,11S,13S)-2-acetyloxy-8,11-dihydroxy-5,5,9-trimethyl-14-methylidene-3,15-dioxo-6-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate | 101938882 | Click to see | 448.50 | unknown |
https://doi.org/10.1016/S0031-9422(01)00245-X https://doi.org/10.1016/S0031-9422(97)00416-0 |
| [(1R,2R,4R,6S,8S,9S,10S,11S,13S)-2,6-diacetyloxy-8-hydroxy-5,5,9-trimethyl-14-methylidene-3,15-dioxo-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate | 101938881 | Click to see | 490.50 | unknown | https://doi.org/10.1016/S0031-9422(97)00416-0 |
| [(1R,2S,3R,5S,6R,8S,9S,10S,11R,15S)-3-acetyloxy-6-(ethoxymethyl)-9,10-dihydroxy-12,12-dimethyl-7-oxo-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-15-yl] acetate | 100937097 | Click to see | 494.60 | unknown | https://doi.org/10.1055/S-2006-960818 |
| [(1R,2S,3R,5S,6S,8S,9S,10S,11R,15S)-3-acetyloxy-6-(ethoxymethyl)-9,10-dihydroxy-12,12-dimethyl-7-oxo-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-15-yl] acetate | 100937099 | Click to see | 494.60 | unknown | https://doi.org/10.1055/S-2006-960818 |
| [(1S,2R,4R,6S,8S,9S,10S,11S,13S,15R)-2-acetyloxy-8,11,15-trihydroxy-5,5,9-trimethyl-14-methylidene-3-oxo-6-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate | 101938883 | Click to see | 450.50 | unknown |
https://doi.org/10.1016/S0031-9422(01)00245-X https://doi.org/10.1016/S0031-9422(97)00416-0 |
| [3-Acetyloxy-6-(ethoxymethyl)-9,10-dihydroxy-12,12-dimethyl-7-oxo-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-15-yl] acetate | 163041809 | Click to see | 494.60 | unknown | https://doi.org/10.1055/S-2006-960818 |
| 2,12,16-Trihydroxy-5-(hydroxymethyl)-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-11,15-dione | 14807615 | Click to see CC1(CCCC2(C1CC(C34C2C(=O)C(C(C3O)C(=C)C4=O)O)O)C)CO | 364.40 | unknown | https://doi.org/10.1016/J.TETLET.2011.08.133 |
| rabdoloxin A | 45271373 | Click to see CC1(CCCC2(C1CC(C34C2C(=O)C(C(C3O)C(=C)C4=O)O)O)C)CO | 364.40 | unknown | https://doi.org/10.1016/J.TETLET.2011.08.133 |
| > Lipids and lipid-like molecules / Prenol lipids / Terpene lactones / Diterpene lactones | |||||
| (14,18-Dihydroxy-7,7-dimethyl-17-methylidene-2-oxo-3,10-dioxapentacyclo[14.2.1.01,13.04,12.08,12]nonadecan-9-yl) acetate | 162904647 | Click to see CC(=O)OC1C2C(CCC3C2(CO1)C4C(CC5CC4(C(C5=C)O)C(=O)O3)O)(C)C | 406.50 | unknown | https://doi.org/10.1055/S-2006-960818 |
| [(1S,4S,8R,9S,12S,13S,14S,16S,18R)-14,18-dihydroxy-7,7-dimethyl-17-methylidene-2-oxo-3,10-dioxapentacyclo[14.2.1.01,13.04,12.08,12]nonadecan-9-yl] acetate | 100937098 | Click to see CC(=O)OC1C2C(CCC3C2(CO1)C4C(CC5CC4(C(C5=C)O)C(=O)O3)O)(C)C | 406.50 | unknown | https://doi.org/10.1055/S-2006-960818 |
| > Lipids and lipid-like molecules / Prenol lipids / Triterpenoids | |||||
| [(3S,4aR,6aR,6bS,8aS,12aS,14aR,14bR)-8a-formyl-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl] acetate | 14829106 | Click to see | 482.70 | unknown | via CMAUP database |
| 3-O-Acetyloleanolic Acid | 151202 | Click to see | 498.70 | unknown | via CMAUP database |
| Oleanolic Acid | 10494 | Click to see | 456.70 | unknown | via CMAUP database |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives | |||||
| 22-Dehydroclerosterol | 15608667 | Click to see | 410.70 | unknown | via CMAUP database |
| > Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Tertiary alcohols | |||||
| 4-Hydroxy-4-(2-hydroxyethyl)cyclohexan-1-one | 184824 | Click to see | 158.19 | unknown | via CMAUP database |
| > Organoheterocyclic compounds / Benzofurans | |||||
| (3aR,7aS)-Hexahydro-3a-hydroxy-6(2H)-benzofuranone | 10975728 | Click to see | 156.18 | unknown | via CMAUP database |
| (3aS,4R,7aS)-3a,4-dihydroxy-2,3,4,5,7,7a-hexahydro-1-benzofuran-6-one | 10749706 | Click to see | 172.18 | unknown | via CMAUP database |
| Cleroindicin E | 11744892 | Click to see | 158.19 | unknown | via CMAUP database |
| > Phenylpropanoids and polyketides / Flavonoids / Flavones | |||||
| 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-[2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]oxychromen-4-one | 57339948 | Click to see C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(OC4O)CO)O)O)O)O | 464.40 | unknown | via CMAUP database |
| Apigenin | 5280443 | Click to see C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O | 270.24 | unknown | via CMAUP database |
| Scutellarein | 5281697 | Click to see C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O)O | 286.24 | unknown | via CMAUP database |
| > Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glucuronides / Flavonoid-7-O-glucuronides | |||||
| beta-D-Glucopyranosiduronic acid, 2-(3,4-dihydroxyphenyl)-5-hydroxy-6-methoxy-4-oxo-4H-1-benzopyran-7-yl | 158227 | Click to see | 492.40 | unknown | via CMAUP database |
| Hispidulin 7-glucuronide | 5318059 | Click to see | 476.40 | unknown | via CMAUP database |
| Scutellarin | 185617 | Click to see | 462.40 | unknown | via CMAUP database |
| > Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 6-O-methylated flavonoids | |||||
| Hispidulin | 5281628 | Click to see | 300.26 | unknown | via CMAUP database |
| Nepetin | 5317284 | Click to see | 316.26 | unknown | via CMAUP database |
| Pectolinarigenin | 5320438 | Click to see COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C(=C3O)OC)O | 314.29 | unknown | via CMAUP database |
| > Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids | |||||
| 5-Hydroxy-6,7,3',4'-Tetramethoxyflavone | 152430 | Click to see | 358.30 | unknown | via CMAUP database |
Collections Top
| In private collections | 0 |
| In public collections | 0 |