Isodon albopilosus

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Internal ID UUID643fdf7af1540150903256
Scientific name Isodon albopilosus
Authority (C.Y.Wu & H.W.Li) H.Hara
First published in J. Jap. Bot. 60: 233 (1985)

Ethnobotanical Use Top

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General Uses Top

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Common products:
Isodon albopilosus is not used in major commodity trade. Products are restricted to research-grade extracts and isolated specialized metabolites from aerial tissues.

Industrial and craft applications:
The plant is used as a source of phenolic specialized metabolites for model studies in natural products chemistry and metabolite profiling. Extracts serve in phytochemical screening and chemotaxonomic comparisons within the Lamiaceae. Tissue-culture and micropropagation protocols support controlled production and taxonomic verification, with herbarium material archived in botanical databases.

Food and beverages (non-medicinal):
No documented culinary or beverage uses.

Colorants and tanning:
Leaves accumulate phenolics (rosmarinic acid class, flavonoids) with a polyphenolic profile that is characteristic of the Lamiaceae. Rosmarinic acid and related polyphenols provide readily extractable brown–brownish colors and function as weak protein-binding agents, properties common to labiate phenolics; however, no specific dye/tannin applications have been reported for this species.

Wood and fiber:
Not applicable; I. albopilosus is an herbaceous subshrub without documented timber or fiber use.

Fragrance and cosmetics:
No documented fragrance or cosmetic uses; extracts are limited to analytical and research contexts.

Properties relevant to use:
Aerial tissues yield diterpenoids of the ent-kaurane type, phenolics (notably rosmarinic acid), flavonoids, and anthocyanins in stems. These chemistries are stable under ambient conditions and amenable to standard extraction and LC/MS profiling. As in other Isodon species, diterpenoid composition is chemotaxonomically informative.

Standards and regulation:
No industry or regulatory standards for I. albopilosus extracts. Products are handled under general laboratory and biodiversity-access regulations in China and adjacent countries.

Sustainability and sourcing:
The species is collected for research from natural habitats in southwestern China and northern Myanmar at ~1200–2400 m. No conservation status assessments or cultivation data are documented; sustainable sampling is advised to avoid local depletion. Herbarium specimens and cryo-collections provide non-extractive research resources.

Synonyms Top

Scientific name Authority First published in
Rabdosia albopilosa C.Y.Wu & H.W.Li Fl. Reipubl. Popularis Sin. 66: 590 (1977)

Common names Top

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Language Common/alternative name
Chinese 白柔毛香茶菜

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000217813
Tropicos 17607248
KEW urn:lsid:ipni.org:names:915108-1
The Plant List kew-102890
Open Tree Of Life 6084570
NCBI Taxonomy 2494282
IPNI 915108-1
GBIF 5610150
EOL 2898928

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Unveiling the Potential of Ent-Kaurane Diterpenoids: Multifaceted Natural Products for Drug Discovery Kibet S, Kimani NM, Mwanza SS, Mudalungu CM, Santos CB, Tanga CM Pharmaceuticals (Basel) 16-Apr-2024
PMCID:PMC11054903
doi:10.3390/ph17040510
PMID:38675469
Molecular and morphological evidence for a new species of Isodon (Lamiaceae) from southern China Chen YP, Huang CZ, Zhao Y, Xiang CL Plant Divers 14-Jul-2020
PMCID:PMC7987569
doi:10.1016/j.pld.2020.06.004
PMID:33778225
Alboatisins A-C, ent-atisene diterpenoids from Isodon albopilosus. Huang SX, Zhou Y, Yang LB, Zhao Y, Li SH, Lou LG, Han QB, Ding LS, Sun HD J Nat Prod 01-Jun-2007
doi:10.1021/NP070086A
PMID:17497809
ent-Kaurane Diterpenoids from Isodon albopilosus. Huang SX, Zhao QS, Xu G, Xiao WL, Li RT, Hou AJ, Peng SL, Ding LS, Sun HD J Nat Prod 01-Dec-2005
doi:10.1021/NP050342O
PMID:16378369

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Kaurane diterpenoids
(1R,2R,4S,5S,9R,10S,13S,16S)-2,16-dihydroxy-5,9-dimethyl-14-methylidene-15-oxotetracyclo[11.2.1.01,10.04,9]hexadecane-5-carbaldehyde 162962205 Click to see 332.40 unknown https://doi.org/10.1021/NP050342O
(1R,2R,4S,5S,9S,10S,12S,13S,14R,16R)-2,12,16-trihydroxy-5,9,14-trimethyl-15-oxotetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid 162981684 Click to see 366.40 unknown https://doi.org/10.1021/NP050342O
(1R,2R,4S,5S,9S,10S,13S,16S)-2,16-dihydroxy-5,9-dimethyl-14-methylidene-15-oxotetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid 163102056 Click to see 348.40 unknown https://doi.org/10.1021/NP050342O
(1S,2R,4S,5S,9R,10S,13S,14R,15R,16S)-2,15,16-trihydroxy-5-(hydroxymethyl)-5,9,14-trimethyltetracyclo[11.2.1.01,10.04,9]hexadecan-12-one 162887726 Click to see CC1C2C(C3(C1O)C(CC4C(CCCC4(C3CC2=O)C)(C)CO)O)O 352.50 unknown https://doi.org/10.1021/NP050342O
(2,12,16-Trihydroxy-5,9-dimethyl-14-methylidene-15-oxo-5-tetracyclo[11.2.1.01,10.04,9]hexadecanyl)methyl acetate 74315805 Click to see CC(=O)OCC1(CCCC2(C1CC(C34C2CC(C(C3O)C(=C)C4=O)O)O)C)C 392.50 unknown https://doi.org/10.1021/NP050342O
(5-Formyl-2,12,16-trihydroxy-5,9-dimethyl-14-methylidene-15-tetracyclo[11.2.1.01,10.04,9]hexadecanyl) acetate 73040964 Click to see CC(=O)OC1C(=C)C2C(CC3C1(C2O)C(CC4C3(CCCC4(C)C=O)C)O)O 392.50 unknown https://doi.org/10.1021/NP050342O
[(1S,2R,4S,5S,9R,10S,12S,13R,15R,16R)-2,12,16-trihydroxy-5-(hydroxymethyl)-5,9-dimethyl-14-methylidene-15-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 162987989 Click to see CC(=O)OC1C(=C)C2C(CC3C1(C2O)C(CC4C3(CCCC4(C)CO)C)O)O 394.50 unknown https://doi.org/10.1021/NP050342O
[(1S,2R,4S,5S,9R,10S,12S,15R,16R)-2,12,16-trihydroxy-5-(hydroxymethyl)-5,9-dimethyl-14-methylidene-15-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 163187502 Click to see 394.50 unknown https://doi.org/10.1021/NP050342O
[(1S,2R,4S,5S,9R,10S,13S,15R,16R)-2,16-dihydroxy-5-(hydroxymethyl)-5,9-dimethyl-14-methylidene-15-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 163037346 Click to see 378.50 unknown https://doi.org/10.1021/NP050342O
[(1S,2R,4S,5S,9R,10S,15R,16R)-2,16-dihydroxy-5-(hydroxymethyl)-5,9-dimethyl-14-methylidene-15-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 163194072 Click to see 378.50 unknown https://doi.org/10.1021/NP050342O
[(1S,2R,4S,5S,9S,10S,12S,13R,15R,16R)-5-formyl-2,12,16-trihydroxy-5,9-dimethyl-14-methylidene-15-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 162900016 Click to see CC(=O)OC1C(=C)C2C(CC3C1(C2O)C(CC4C3(CCCC4(C)C=O)C)O)O 392.50 unknown https://doi.org/10.1021/NP050342O
[(1S,2R,4S,5S,9S,10S,12S,15R,16R)-5-formyl-2,12,16-trihydroxy-5,9-dimethyl-14-methylidene-15-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 163190344 Click to see 392.50 unknown https://doi.org/10.1021/NP050342O
[2,12,16-Trihydroxy-14-(hydroxymethyl)-5,9-dimethyl-15-oxo-5-tetracyclo[11.2.1.01,10.04,9]hexadecanyl]methyl acetate 73007267 Click to see 410.50 unknown https://doi.org/10.1021/NP050342O
[2,12,16-Trihydroxy-5-(hydroxymethyl)-5,9-dimethyl-14-methylidene-15-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 73028825 Click to see 394.50 unknown https://doi.org/10.1021/NP050342O
[2,16-Dihydroxy-5-(hydroxymethyl)-5,9-dimethyl-14-methylidene-15-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate 73033607 Click to see CC(=O)OC1C(=C)C2CCC3C1(C2O)C(CC4C3(CCCC4(C)CO)C)O 378.50 unknown https://doi.org/10.1021/NP050342O
2,12,16-Trihydroxy-5-(hydroxymethyl)-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecan-15-one 14563761 Click to see CC1(CCCC2(C1CC(C34C2CC(C(C3O)C(=C)C4=O)O)O)C)CO 350.40 unknown https://doi.org/10.1021/NP050342O
2,12,16-Trihydroxy-5,9-dimethyl-14-methylidene-15-oxotetracyclo[11.2.1.01,10.04,9]hexadecane-5-carbaldehyde 14563769 Click to see 348.40 unknown https://doi.org/10.1021/NP050342O
2,12,16-Trihydroxy-5,9-dimethyl-14-methylidene-15-oxotetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid 75051952 Click to see 364.40 unknown https://doi.org/10.1021/NP050342O
2,12,16-Trihydroxy-5,9,14-trimethyl-15-oxotetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid 75051953 Click to see CC1C2C(CC3C4(CCCC(C4CC(C3(C2O)C1=O)O)(C)C(=O)O)C)O 366.40 unknown https://doi.org/10.1021/NP050342O
2,15,16-Trihydroxy-5-(hydroxymethyl)-5,9,14-trimethyltetracyclo[11.2.1.01,10.04,9]hexadecan-12-one 73026169 Click to see 352.50 unknown https://doi.org/10.1021/NP050342O
2,16-Dihydroxy-5-(hydroxymethyl)-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecan-15-one 72742985 Click to see 334.40 unknown https://doi.org/10.1021/NP050342O
2,16-Dihydroxy-5,9-dimethyl-14-methylidene-15-oxotetracyclo[11.2.1.01,10.04,9]hexadecane-5-carbaldehyde 73009339 Click to see 332.40 unknown https://doi.org/10.1021/NP050342O
2,16-Dihydroxy-5,9-dimethyl-14-methylidene-15-oxotetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid 72983420 Click to see CC12CCCC(C1CC(C34C2CCC(C3O)C(=C)C4=O)O)(C)C(=O)O 348.40 unknown https://doi.org/10.1021/NP050342O
5-(Hydroxymethyl)-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-2,12,16-triol 73062693 Click to see CC1(CCCC2(C1CC(C34C2CC(C(C3O)C(=C)C4)O)O)C)CO 336.50 unknown https://doi.org/10.1021/NP050342O
7,12,14-Trihydroxy-15-oxokaur-16-en-18-al 3035527 Click to see 348.40 unknown https://doi.org/10.1021/NP050342O
Albopilosin A 24721136 Click to see CC(=O)OCC1(CCCC2(C1CC(C34C2CC(C(C3O)C(=C)C4=O)O)O)C)C 392.50 unknown https://doi.org/10.1021/NP050342O
Albopilosin B 11610905 Click to see CC(=O)OC1C(=C)C2C(CC3C1(C2O)C(CC4C3(CCCC4(C)CO)C)O)O 394.50 unknown https://doi.org/10.1021/NP050342O
Albopilosin C 11646838 Click to see CC(=O)OC1C(=C)C2C(CC3C1(C2O)C(CC4C3(CCCC4(C)C=O)C)O)O 392.50 unknown https://doi.org/10.1021/NP050342O
Albopilosin D 11625073 Click to see 378.50 unknown https://doi.org/10.1021/NP050342O
Albopilosin E 11602783 Click to see 352.50 unknown https://doi.org/10.1021/NP050342O
Albopilosin F 11560591 Click to see 410.50 unknown https://doi.org/10.1021/NP050342O
Albopilosin G 11688617 Click to see 336.50 unknown https://doi.org/10.1021/NP050342O
Albopilosin H 11566162 Click to see CC1(CCCC2(C1CC(C34C2CCC(C3O)C(=C)C4=O)O)C)C=O 332.40 unknown https://doi.org/10.1021/NP050342O
Albopilosin I 11494013 Click to see 348.40 unknown https://doi.org/10.1021/NP050342O
Amethystonoic acid 44584280 Click to see CC12CCCC(C1CC(C34C2CC(C(C3O)C(=C)C4=O)O)O)(C)C(=O)O 364.40 unknown https://doi.org/10.1021/NP050342O
Coetsanoic acid 44584281 Click to see 366.40 unknown https://doi.org/10.1021/NP050342O
Excisanin C 15011613 Click to see 334.40 unknown https://doi.org/10.1021/NP050342O
Macrocalyxin C 14563770 Click to see CC1(CCCC2(C1CC(C34C2CC(C(C3O)C(=C)C4=O)O)O)C)C=O 348.40 unknown https://doi.org/10.1021/NP050342O
rabdokunmin C 14563762 Click to see CC1(CCCC2(C1CC(C34C2CC(C(C3O)C(=C)C4=O)O)O)C)CO 350.40 unknown https://doi.org/10.1021/NP050342O
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Villanovane, atisane, trachylobane or helvifulvane diterpenoids / Atisane diterpenoids
(1R,2R,4S,5S,9S,10S,12S,15S,16S)-2,15,16-trihydroxy-5-(hydroxymethyl)-5,9-dimethyl-13-methylidenetetracyclo[10.2.2.01,10.04,9]hexadecan-14-one 162940349 Click to see 350.40 unknown https://doi.org/10.1021/NP070086A
2,13,14-Trihydroxy-5,9-dimethyl-16-methylidene-15-oxotetracyclo[10.2.2.01,10.04,9]hexadecane-5-carbaldehyde 73316577 Click to see 348.40 unknown https://doi.org/10.1021/NP070086A
Alboatisin B 16737107 Click to see 348.40 unknown https://doi.org/10.1021/NP070086A
Alboatisin C 16737109 Click to see CC1(CCCC2(C1CC(C34C2CC(C(C3)O)C(=C)C4=O)O)C)CO 334.40 unknown https://doi.org/10.1021/NP070086A
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Diterpene glycosides
(1R,2R,4S,5S,9R,10S,12S,13R,14R,16R)-2,12,16-trihydroxy-5,9,14-trimethyl-5-[[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]tetracyclo[11.2.1.01,10.04,9]hexadecan-15-one 162983309 Click to see 514.60 unknown https://doi.org/10.1021/NP050342O
2,12,16-Trihydroxy-5,9,14-trimethyl-5-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]tetracyclo[11.2.1.01,10.04,9]hexadecan-15-one 73072752 Click to see 514.60 unknown https://doi.org/10.1021/NP050342O
Albopilosin J 11720463 Click to see CC1C2C(CC3C4(CCCC(C4CC(C3(C2O)C1=O)O)(C)COC5C(C(C(C(O5)CO)O)O)O)C)O 514.60 unknown https://doi.org/10.1021/NP050342O

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