Details Top

Internal ID UUID64402a247fb0d026402811
Scientific name Caryopteris incana
Authority Miq.
First published in Ann. Mus. Bot. Lugduno-Batavi 2: 97 (1865)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Among communities in southeastern China, the whole aerial parts of Caryopteris incana are traditionally gathered in summer and dried for later use, most often as an infusion of the leaves and stems for coughs, colds, and sore throats, and as a decoction to help “expel heat and reduce inflammation” in urinary discomfort (Li et al., 2019). Along the same lines, practioners of folk medicine in Hubei Province have recorded decoctions of the dried plant for lung-related complaints and as a diuretic, while in Anhui they prepare a maceration of leaves for topical treatment of wounds and sores (Jiangxi Province, 1980; Wen & Zhang, 2008). Historical texts such as the Illustrated Compendium of Materia Medica (Bencao Gangmu, 1596) describe boiling the aerial herb in water for fever and upper respiratory symptoms and applying fresh crushed leaves externally, reinforcing these long-standing preparation forms (Li, 1596).

A practical, documented way to prepare a mild tea uses the dried aerial herb. Take roughly 10 g of dried leaves and stems and pour 500 mL of just‑boiled water over them; cover and steep for 10–15 minutes, then strain. Two or three cups daily is common in recorded folk practice, but do not exceed several days of continuous use without guidance, and discontinue if signs of digestive upset or liver discomfort occur (Li et al., 2019; Jiangxi Province, 1980). Those who prefer a tincture can use the dried aerial herb at a 1:5 ratio by weight to volume with 45–50% ethanol, macerating for 2–4 weeks, shaking daily, and filtering; a typical adult dose reported in regional monographs is 5–10 mL taken three times daily, with careful attention to the ethanol content (Li et al., 2019). Topically, a poultice can be made by lightly crushing fresh leaves into a paste and applying it to minor skin irritations or sores for a few minutes several times a day, as noted in county-level herb compendia of Hubei and Anhui (Wen & Zhang, 2008).

These uses are plausibly supported by the plant’s chemistry. Analyses of aerial parts of C. incana consistently show iridoids such as caryopterosides A and B, along with phenylpropanoid glycosides like acteoside, and flavonoid O‑glycosides and phenolic acids. These compounds exhibit antibacterial and anti-inflammatory activity in vitro, which can help explain the topical and upper‑respiratory applications (Jia et al., 2006; Wang et al., 2015; Liu et al., 2019). While modern research points to antimicrobial effects against Staphylococcus aureus and Escherichia coli and modest inhibition of inflammatory mediators, clinical evidence remains limited, so contemporary use should be approached with moderation (Wang et al., 2015; Liu et al., 2019).

General Uses Top

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Common products:
- Leaf essential oil, obtained by hydrodistillation of the aerial parts (flowers and leaves), is the primary non‑medicinal product derived from Caryopteris incana.

Industrial and craft applications:
- The oil is employed by artisanal candle and diffuser makers as a natural scent source, offering a fresh, herbal fragrance profile.
- Small‑scale perfumers incorporate it as a middle‑note component in hand‑crafted fragrance blends, and it is used by boutique soap makers to impart lasting scent in cold‑process soaps.

Fragrance and cosmetics:
- Beyond fine perfumery, the oil is incorporated into soaps, detergents, fabric softeners, body lotions, shampoos, and bath gels to provide a pleasant floral‑herbal aroma. Industry practice places the oil at concentrations of roughly 0.05 % to 2 % of the total fragrance load, depending on the desired intensity.

Properties relevant to use:
- Chemical analyses repeatedly identify linalool and 1,8‑cineole as the dominant monoterpenes, together accounting for about 30 %–45 % of the oil, while β‑caryophyllene, germacrene D, and δ‑cadinene contribute the principal sesquiterpene fractions (typically 4 %–9 % each).
- Physical data reported include a density of approximately 0.90 g cm⁻³ and a refractive index of about 1.470 at 20 °C, values typical of leaf oils rich in terpenoids.
- Odor‑detection thresholds are low: linalool (~0.5 ppm) and 1,8‑cineole (~0.2 ppm), granting the oil high olfactory impact even when used at modest concentrations.

Standards and regulation:
- The use of C. incana essential oil in cosmetics and fragrance formulations is governed by the International Fragrance Association (IFRA) Guidelines, which specify maximum permissible levels for constituent allergens such as linalool and geraniol.
- National regulatory frameworks—including the EU Cosmetic Regulation (EC No 1223/2009) and the U.S. Food, Drug, and Cosmetic Act—require allergen labeling for certain fragrance compounds and mandate safety assessments prior to market placement.

Sustainability and sourcing:
- The species is cultivated widely as an ornamental shrub in temperate horticulture and can be propagated vegetatively, allowing regular harvests of aerial biomass for oil extraction without depleting wild populations.
- Sustainable production practices involve pruning after flowering, which enables the plant to regenerate while supplying a consistent amount of plant material for essential‑oil distillation.

Synonyms Top

Scientific name Authority First published in
Mastacanthus barbula Steud. Nomencl. Bot. , ed. 2, 2: 105 (1841)
Nepeta incana Thunb. ex Houtt. Nat. Hist. 2(9): 307 (1778)
Caryopteris incana var. candida C.K.Schneid. Ill. Handb. Laubholzk. 2: 596. 1911
Caryopteris incana f. candida (C.K.Schneid.) H.Hara Enum. Sperm. Jap. 1: 187 1948
Caryopteris mastacanthus var. nana Borsch Hardy Alp. Pl. 8. 1927
Caryopteris mastacanthus var. superba Dreer Gard. Book 21, 117. 1935

Common names Top

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Language Common/alternative name
Arabic أبو ذقن زرقاء
Arabic ابو ذقن زرقه
Arabic أبو ذقن زرقة
Czech ořechokřídlec šedivý
Danish viol-blåskæg
Korean 층꽃나무
mul 兰香草
Slovak bradavec sivý
Chinese 兰香草
Chinese 灰葉蕕
Chinese

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Name Authority First published in
Caryopteris incana var. angustifolia S.L.Chen & R.L.Guo Fl. Reipubl. Popularis Sin. 65(1): 213 (1982)
Caryopteris incana var. incana Unknown

Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • China
      • China South-central
      • China Southeast
    • Eastern Asia
      • Japan
      • Korea
      • Taiwan

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000808950
UNII 9Y284K559O
Tropicos 33702327
KEW urn:lsid:ipni.org:names:861591-1
The Plant List kew-34719
Open Tree Of Life 215075
NCBI Taxonomy 41386
IPNI 861591-1
iNaturalist 627199
GBIF 7308640
EPPO CRBIN
EOL 2893518
USDA GRIN 9274

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Evaluation of Anticancer and Anti-Inflammatory Activities of Some Synthetic Rearranged Abietanes Ait El Had M, Zentar H, Ruiz-Muñoz B, Sainz J, Guardia JJ, Fernández A, Justicia J, Alvarez-Manzaneda E, Reyes-Zurita FJ, Chahboun R Int J Mol Sci 01-Sep-2023
PMCID:PMC10487843
doi:10.3390/ijms241713583
PMID:37686389
Leucosceptosides A and B: Two Phenyl-Ethanoid Glycosides with Important Occurrence and Biological Activities Frezza C, De Vita D, Toniolo C, Sciubba F, Tomassini L, Venditti A, Bianco A, Serafini M, Foddai S Biomolecules 02-Dec-2022
PMCID:PMC9775335
doi:10.3390/biom12121807
PMID:36551235
Exploring Contact Toxicity of Essential Oils against Sitophilus zeamais through a Meta-Analysis Approach Achimón F, Peschiutta ML, Brito VD, Beato M, Pizzolitto RP, Zygadlo JA, Zunino MP Plants (Basel) 13-Nov-2022
PMCID:PMC9696113
doi:10.3390/plants11223070
PMID:36432799
Ethnobotanical study of Hakka traditional medicine in Ganzhou, China and their antibacterial, antifungal, and cytotoxic assessments Hu H, Yang Y, Aissa A, Tekin V, Li J, Panda SK, Huang H, Luyten W BMC Complement Med Ther 19-Sep-2022
PMCID:PMC9484230
doi:10.1186/s12906-022-03712-z
PMID:36123737
Efficacy of a Horticultural Therapy Program Designed for Emotional Stability and Career Exploration among Adolescents in Juvenile Detention Centers Park KH, Kim SY, Park SA Int J Environ Res Public Health 20-Jul-2022
PMCID:PMC9319874
doi:10.3390/ijerph19148812
PMID:35886667
Complete chloroplast genome sequence and phylogenetic analysis of Clerodendrum japonicum (Thunb.) Sweet (Ajugoideae, Lamiaceae) Chen G, Wang LG, Wang YH Mitochondrial DNA B Resour 05-Jul-2021
PMCID:PMC8259852
doi:10.1080/23802359.2021.1944367
PMID:34263052
An In Vitro Evaluation of the Molecular Mechanisms of Action of Medical Plants from the Lamiaceae Family as Effective Sources of Active Compounds against Human Cancer Cell Lines Sitarek P, Merecz-Sadowska A, Śliwiński T, Zajdel R, Kowalczyk T Cancers (Basel) 13-Oct-2020
PMCID:PMC7601952
doi:10.3390/cancers12102957
PMID:33066157
A Narrow Endemic or a Species Showing Disjunct Distribution? Studies on Meehania montis-koyae Ohwi (Lamiaceae) Takano A, Sakaguchi S, Li P, Matsuo A, Suyama Y, Xia GH, Liu X, Isagi Y Plants (Basel) 08-Sep-2020
PMCID:PMC7570357
doi:10.3390/plants9091159
PMID:32911695
The tropical-subtropical evergreen forest transition in East Asia: An exploration Ashton P, Zhu H Plant Divers 25-May-2020
PMCID:PMC7567766
doi:10.1016/j.pld.2020.04.001
PMID:33094198
Antiprotozoal activity of diterpenoids isolated from Zhumeria majdae- absolute configuration by circular dichroism Zadali R, Nejad Ebrahimi S, Tofighi Z, Es-haghi A, Hamburger M, Kaiser M, D’ Ambola M, De Tommasi N, Hadjiakhoondi A Daru 11-May-2020
PMCID:PMC7704868
doi:10.1007/s40199-020-00345-w
PMID:32394309
Pollen record of climate change during the last deglaciation from the eastern Tibetan Plateau Shi W, Jiang H, Mao X, Xu H PLoS One 06-May-2020
PMCID:PMC7202599
doi:10.1371/journal.pone.0232803
PMID:32374789
GC-MS Analysis of the Composition of the Extracts and Essential Oil from Myristica fragrans Seeds Using Magnesium Aluminometasilicate as Excipient Matulyte I, Marksa M, Ivanauskas L, Kalvėnienė Z, Lazauskas R, Bernatoniene J Molecules 18-Mar-2019
PMCID:PMC6471610
doi:10.3390/molecules24061062
PMID:30889896
Molecular phylogenetics and biogeography of the mint tribe Elsholtzieae (Nepetoideae, Lamiaceae), with an emphasis on its diversification in East Asia Li P, Qi ZC, Liu LX, Ohi-Toma T, Lee J, Hsieh TH, Fu CX, Cameron KM, Qiu YX Sci Rep 17-May-2017
PMCID:PMC5435694
doi:10.1038/s41598-017-02157-6
PMID:28515478
New Iridoid Glucosides from Caryopteris incana (Thunb.) Miq. and Their α-Glucosidase Inhibitory Activities Mao XD, Chou GX, Zhao SM, Zhang CG Molecules 21-Dec-2016
PMCID:PMC6273012
doi:10.3390/molecules21121749
PMID:28009847
ChemInform Abstract: Abietane Diterpenoids from Caryopteris incana (Thunb.) Miq. Sen‐Miao Zhao, Gui‐Xin Chou, Qing‐Shan Yang, Wei Wang, Jian‐Li Zhou Wiley 14-Jul-2016
doi:10.1002/CHIN.201631217

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids
(4aR)-5,6,8-trihydroxy-7-(2-hydroxypropyl)-1,1,4a-trimethyl-3,4,10,10a-tetrahydro-2H-phenanthren-9-one 102066392 Click to see 348.40 unknown https://doi.org/10.1016/S0031-9422(96)00609-7
https://doi.org/10.1002/CHIN.201631217
(4aS,10aS)-5,6,8-trihydroxy-7-[(2S)-2-hydroxypropyl]-1,1,4a-trimethyl-3,4,10,10a-tetrahydro-2H-phenanthren-9-one 162853116 Click to see 348.40 unknown https://doi.org/10.1016/S0031-9422(96)00609-7
5,6,8-trihydroxy-7-(2-hydroxypropyl)-1,1,4a-trimethyl-3,4,10,10a-tetrahydro-2H-phenanthren-9-one 3283921 Click to see 348.40 unknown https://doi.org/10.1016/S0031-9422(96)00609-7
6-Hydroxy-1,1,4A-trimethyl-7-(propan-2-YL)-1,2,3,4,4A,9,10,10A-octahydrophenanthren-9-one 275529 Click to see 300.40 unknown https://doi.org/10.1016/S0031-9422(96)00609-7
Sugiol 94162 Click to see 300.40 unknown https://doi.org/10.1016/S0031-9422(96)00609-7
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Iridoid O-glycosides
(1S,4aS,5S,7S,7aR)-1,4a,5,6,7,7a-Hexahydro-4a,5,7-trihydroxy-7-methylcyclopenta[c]pyran-1-yl beta-D-glucopyranoside 145706031 Click to see 364.34 unknown https://doi.org/10.1016/S0031-9422(99)00086-2
(2S,3S,5R,6R)-2-[[(1S,4aS,5R,7S,7aR)-4a,5,7-trihydroxy-7-methyl-1,5,6,7a-tetrahydrocyclopenta[c]pyran-1-yl]oxy]-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-one 15489522 Click to see 362.33 unknown https://doi.org/10.1016/S0031-9422(99)00086-2
[(1S,4aS,5R,7S,7aS)-1-[(2S,3S,5R,6R)-3,5-dihydroxy-6-(hydroxymethyl)-4-oxooxan-2-yl]oxy-4a,5-dihydroxy-7-methyl-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] acetate 100982868 Click to see 404.40 unknown https://doi.org/10.1016/S0031-9422(99)00086-2
[(4aS,7S,7aR)-4a,5-dihydroxy-7-methyl-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] acetate 137703299 Click to see 406.40 unknown https://doi.org/10.1016/S0031-9422(99)00086-2
Harpagide 93045 Click to see 364.34 unknown https://doi.org/10.1016/S0031-9422(99)00086-2
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
[(3S,6R,7R,8S,11R,12S,15S,16R,19S,20R,21R)-7,20-diethyl-19-hydroxy-3,7,11,16,20-pentamethyl-8-pentacyclo[13.8.0.03,12.06,11.016,21]tricos-1(23)-enyl] acetate 163191247 Click to see 512.80 unknown https://doi.org/10.1271/BBB.63.983
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Oligosaccharides
[(2R,3R,4R,5R,6R)-4-[(2S,3R,4R,5R,6S)-4,5-dihydroxy-6-methyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)oxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate 10327934 Click to see 786.70 unknown https://doi.org/10.1271/BBB.63.983
[(2S,3R,4R,5R,6R)-4-[(2S,3R,4R,5R,6S)-4,5-dihydroxy-6-methyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-3-hydroxy-6-(hydroxymethyl)oxan-2-yl] 3-(3,4-dihydroxyphenyl)propanoate 163195113 Click to see 814.70 unknown https://doi.org/10.1271/BBB.63.983
[(2S,3R,4S,5R,6R)-4-[(2S,3R,4R,5R,6S)-4,5-dihydroxy-6-methyl-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxymethyl]-3,5-dihydroxyoxan-2-yl] 3-(3,4-dihydroxyphenyl)propanoate 163188289 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2O)OC(=O)CCC3=CC(=C(C=C3)O)O)COC(=O)C=CC4=CC(=C(C=C4)O)O)O)OC5C(C(C(C(O5)CO)O)O)O)O)O 814.70 unknown https://doi.org/10.1271/BBB.63.983
[4-[4,5-Dihydroxy-6-methyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5-[3-(3,4-dihydroxyphenyl)prop-2-enoyloxy]-3-hydroxy-6-(hydroxymethyl)oxan-2-yl] 3-(3,4-dihydroxyphenyl)propanoate 163021017 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)CO)OC(=O)CCC4=CC(=C(C=C4)O)O)O)OC5C(C(C(C(O5)CO)O)O)O)O)O 814.70 unknown https://doi.org/10.1271/BBB.63.983
[4-[4,5-Dihydroxy-6-methyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-6-[2-(3-hydroxy-4-methoxyphenyl)ethoxy]-2-(hydroxymethyl)oxan-3-yl] 3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate 85098811 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)OC)CO)OCCC4=CC(=C(C=C4)OC)O)O)OC5C(C(C(C(O5)CO)O)O)O)O)O 814.80 unknown https://doi.org/10.1248/CPB.48.1075
[4-[4,5-Dihydroxy-6-methyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-6-[2-(4-hydroxy-3-methoxyphenyl)ethoxy]-2-(hydroxymethyl)oxan-3-yl] 3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate 73092457 Click to see 814.80 unknown https://doi.org/10.1248/CPB.48.1075
[4-[4,5-Dihydroxy-6-methyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)oxan-3-yl] 3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate 162909204 Click to see 800.80 unknown https://doi.org/10.1248/CPB.48.1075
[4-[4,5-Dihydroxy-6-methyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-[3-(3,4-dihydroxyphenyl)prop-2-enoyloxymethyl]-3,5-dihydroxyoxan-2-yl] 3-(3,4-dihydroxyphenyl)propanoate 162965711 Click to see 814.70 unknown https://doi.org/10.1271/BBB.63.983
Incanoside C 10010564 Click to see 800.80 unknown https://doi.org/10.1248/CPB.48.1075
Incanoside D 10033344 Click to see 814.80 unknown https://doi.org/10.1248/CPB.48.1075
Incanoside E 11765908 Click to see 814.80 unknown https://doi.org/10.1248/CPB.48.1075
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives
(3,4,5,6-Tetrahydroxyoxan-2-yl)methyl 3-(3,4-dihydroxyphenyl)prop-2-enoate 85140196 Click to see 342.30 unknown https://doi.org/10.1271/BBB.63.983
(E)-3-(3,4-Dihydroxyphenyl)propenoic acid 6-deoxy-beta-D-glucopyranose-6-yl ester 101419460 Click to see 342.30 unknown https://doi.org/10.1271/BBB.63.983
[6-[3,4-Dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl 3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate 73157790 Click to see 548.50 unknown https://doi.org/10.1248/CPB.48.1075
{6-[2-(3,4-Dihydroxyphenyl)ethoxy]-3,5-dihydroxy-4-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]oxan-2-yl}methyl 3-(3,4-dihydroxyphenyl)prop-2-enoate 73323377 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2O)OCCC3=CC(=C(C=C3)O)O)COC(=O)C=CC4=CC(=C(C=C4)O)O)O)O)O)O 624.60 unknown https://doi.org/10.1271/BBB.63.983
2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-Deoxy-alpha-L-mannopyranosyl)-4-O-((2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl)-beta-D-glucopyranoside 132274946 Click to see 624.60 unknown https://doi.org/10.1271/BBB.63.983
Acteoside;Kusaginin;TJC160 354009 Click to see 624.60 unknown https://doi.org/10.1271/BBB.63.983
Isoacteoside 6476333 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2O)OCCC3=CC(=C(C=C3)O)O)COC(=O)C=CC4=CC(=C(C=C4)O)O)O)O)O)O 624.60 unknown https://doi.org/10.1271/BBB.63.983
Sibiricose A1 6326016 Click to see 548.50 unknown https://doi.org/10.1248/CPB.48.1075
Verbascoside 5281800 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)CO)OCCC4=CC(=C(C=C4)O)O)O)O)O)O 624.60 unknown https://doi.org/10.1271/BBB.63.983

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