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Internal ID UUID643fe8718be4b142386042
Scientific name Pogonopus tubulosus
Authority K.Schum.
First published in Fl. Bras. 6(6): 266 (1889)

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Synonyms Top

Scientific name Authority First published in
Howardia febrifuga Wedd. Ann. Sci. Nat., Bot. , sér. 4, 1: 67 (1854)
Howardia richardii Wedd. Ann. Sci. Nat., Bot. , sér. 4, 1: 69 (1854)
Macrocnemum tubulosum A.Rich. ex DC. Prodr. 4: 403 (1830)
Pogonopus febrifugus (Wedd.) Benth. & Hook.f. ex Hieron. Pl. Diaph. Fl. Argent. 139. 1882
Calycophyllum tubulosum DC. Prodr. 4: 367 (1830)
Pogonopus febrifugus var. macrosema Hutch. Bull. Misc. Inform. Kew 1910: 200 (1910)
Chrysoxylon febrifugum Wedd. Hist. Nat. Quinquinas : 100 (1849)
Chrysoxylon tubulosum Kuntze Revis. Gen. Pl. 1: 278 (1891)
Macrocnemum tubulosum A.Rich. Mém. Rubiac. 199 1830

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Southern America
    • Brazil
      • Brazil North
      • Brazil West-central
    • Southern South America
      • Argentina Northwest
      • Paraguay
    • Western South America
      • Bolivia
      • Peru

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000279634
Tropicos 27904055
KEW urn:lsid:ipni.org:names:204805-2
The Plant List kew-162075
Open Tree Of Life 153784
NCBI Taxonomy 128352
IUCN Red List 194014519
IPNI 204805-2
GBIF 5340245
EOL 1111416

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Title Authors Publication Released IDs
IL-6/JAK/STAT3 Signaling in Breast Cancer Metastasis: Biology and Treatment Manore SG, Doheny DL, Wong GL, Lo HW Front Oncol 15-Mar-2022
PMCID:PMC8964978
doi:10.3389/fonc.2022.866014
PMID:35371975
Tubulosine selectively inhibits JAK3 signalling by binding to the ATP‐binding site of the kinase of JAK3 Kim B, Yi EH, Jee J, Jeong AJ, Sandoval C, Park I, Baeg GH, Ye S J Cell Mol Med 17-Jun-2020
PMCID:PMC7339168
doi:10.1111/jcmm.15362
PMID:32558259
Anticancer Activity of Tubulosine through Suppression of Interleukin-6-Induced Janus Kinase 2/Signal Transducer and Activation of Transcription 3 Signaling Kim BH, Yi EH, Li YC, Park IC, Park JY, Ye SK J Breast Cancer 02-Aug-2019
PMCID:PMC6769386
doi:10.4048/jbc.2019.22.e34
PMID:31598337
Larvicidal efficacies of plants from Midwestern Brazil: melianodiol from Guarea kunthiana as a potential biopesticide against Aedes aegypti Sarmento UC, Miguita CH, Almeida LH, Gaban CR, da Silva LM, de Souza AS, Garcez WS, Garcez FR Mem Inst Oswaldo Cruz 13-Jun-2016
PMCID:PMC4957500
doi:10.1590/0074-02760160134
PMID:27333366
Secondary Metabolites from Rubiaceae Species Martins D, Nunez CV Molecules 22-Jul-2015
PMCID:PMC6331836
doi:10.3390/molecules200713422
PMID:26205062
Antimalarial Activity of Alkaloids fromPogonopus tubulosus Michel Sauvain, Christian Moretti, José-Antonio Bravo, Jorgia Callapa, Victoria Muñoz, Enma Ruiz, Bernard Richard, Louisette Le Men-Olivier Wiley 02-Dec-2005
doi:10.1002/(SICI)1099-1573(199605)10:3<198::AID-PTR798>3.0.CO;2-Z

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Emetine alkaloids
Cephaeline 442195 Click to see CCC1CN2CCC3=CC(=C(C=C3C2CC1CC4C5=CC(=C(C=C5CCN4)O)OC)OC)OC 466.60 unknown https://doi.org/10.1002/(SICI)1099-1573(199605)10:3<198::AID-PTR798>3.0.CO;2-Z
Psychotrine 65380 Click to see CCC1CN2CCC3=CC(=C(C=C3C2CC1CC4=NCCC5=CC(=C(C=C54)OC)O)OC)OC 464.60 unknown https://doi.org/10.1002/(SICI)1099-1573(199605)10:3<198::AID-PTR798>3.0.CO;2-Z
> Alkaloids and derivatives / Harmala alkaloids
Tubulosine 72341 Click to see CCC1CN2CCC3=CC(=C(C=C3C2CC1CC4C5=C(CCN4)C6=C(N5)C=CC(=C6)O)OC)OC 475.60 unknown https://doi.org/10.1002/(SICI)1099-1573(199605)10:3<198::AID-PTR798>3.0.CO;2-Z

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