Ophiorrhiza japonica

Details Top

Internal ID UUID643fe541517e6844504118
Scientific name Ophiorrhiza japonica
Authority Blume
First published in Bijdr. Fl. Ned. Ind. : 978 (1826)

Ethnobotanical Use Top

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General Uses Top

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Common products:
Non-fermented (green, white) and fermented (black, oolong, pu’er) leaf teas are marketed as beverages in bulk, bag, and loose-leaf forms. Tea-based food flavors, iced beverages, and extract or concentrate products for the beverage industry are common. Instant or soluble teas, powdered or agglomerated, are produced for retail and foodservice.

Food and beverages (non-medicinal):
Tea serves as a flavoring in confectionery, baked goods, dairy and plant-based analogs, and savory sauces. Caffeine and catechins contribute to bitterness and color; fermentation produces theaflavins and thearubigins characteristic of black and dark teas. In cooked foods, it is used as a colorant or smoke-flavoring (e.g., “tea-smoked” dishes) without health claims.

Fragrance and cosmetics:
Tea essential oil and absolute from leaves or buds are used in fine and functional fragrance. Green tea extract, comprising catechins and caffeine, is employed in perfumery and cosmetics as a fragrance component and sensory modifier (caffeine is used for its bitterness). Compounds from tea (e.g., caffeine, catechins) are used in flavor and fragrance databases.

Colorants and tanning:
Catechins in green teas impart brown hues to water-based colorants. While tea contains tannins, it is not a conventional leather tanning material; use is primarily as a light brown dye in craft or dyeing contexts.

Properties relevant to use:
Caffeine content provides bitterness and sensory impact in beverages and fragrance. Green tea catechins yield pale brown pigments and greenish hues; black tea fermentation produces darker theaflavins and thearubigins. Plant polyphenols are established as reducing agents, giving color and astringency relevant to dyeing and formulation stability.

Standards and regulation:
Beverage products and flavors follow national food standards (e.g., ISO 22000, ISO/TS 22002-1 for catering; EU food law for contaminants; US FDA Title 21 CFR for food and GRAS status of flavors). Cosmetic use is governed by regional frameworks (EU Cosmetic Regulation; US CFR 21) and fragrance materials may be managed under IFRA standards. TEA (INCI: Tea) as a cosmetic ingredient is listed in international inventories (e.g., INCI, EU Cosmetic Ingredient Database).

Sustainability and sourcing:
Leaves are harvested multiple times per year, with yields and quality linked to cultivar, elevation, and processing. Shade-grown teas may reduce yield but improve quality. Manufacturing involves wet withering and mechanical operations; wastewaters are treated per local industrial regulations (ISO 14001). The species is widely cultivated; field and processing sustainability varies by region and certification programs (e.g., ethical trade initiatives).

Synonyms Top

Scientific name Authority First published in
Ophiorrhiza acutiloba Hayata Icon. Pl. Formosan. 2: 86 (1912)
Ophiorrhiza cavaleriei H.Lév. Repert. Spec. Nov. Regni Veg. 13: 177 (1914)
Ophiorrhiza dimorphantha Hayata Icon. Pl. Formosan. 2: 86 (1912)
Ophiorrhiza dimorphantha f. brevistigma Hayata Icon. Pl. Formosan. 2: 87 1912
Ophiorrhiza dimorphantha f. longistigma Hayata Icon. Pl. Formosan. 2: 87 1912
Ophiorrhiza eryei Champ. Hooker's J. Bot. Kew Gard. Misc. 4: 170. 1852 (1852)
Ophiorrhiza japonica var. acutiloba (Hayata) Ohwi Acta Phytotax. Geobot. 7: 195. 1938
Ophiorrhiza japonica var. minor E.H.L.Krause Repert. Spec. Nov. Regni Veg. 12: 489. 1922
Ophiorrhiza japonica var. tashiroi (Maxim.) Ohwi Acta Phytotax. Geobot. 7: 195. 1938
Ophiorrhiza labordei H.Lév. Repert. Spec. Nov. Regni Veg. 13: 177 (1914)
Ophiorrhiza monticola Hayata Icon. Pl. Formosan. 2: 89 (1912)
Ophiorrhiza monticola f. brevistigma Hayata Icon. Pl. Formosan. 2: 89 1912
Ophiorrhiza monticola f. longistigma Hayata Icon. Pl. Formosan. 2: 90 1912
Ophiorrhiza nigricans H.S.Lo Bull. Bot. Res., Harbin 10(2): 53 (1990)
Ophiorrhiza tashiroi Maxim. Bull. Acad. Imp. Sci. Saint-Pétersbourg , sér. 3, 32: 489 (1888)
Ophiorrhiza japonica f. plena T.Yamaz. J. Jap. Bot. 79: 269 (2004)
Ophiorrhiza japonica var. amamiana Hatus. Rep. Co-op. Invest. Ryukyu Isls. Kagoshima Univ. and Ryukyu Univ. 1: 61 (1961)

Common names Top

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Language Common/alternative name
nan choâ-kin-chhaú
nan choâ-kin-chháu
Chinese 蛇根草
Chinese 变黑蛇根草
Chinese 散血草
Chinese 日本蛇根草
Chinese 日本蛇根草(蛇根草)
Chinese 猪菜

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • China
      • China North-central
      • China South-central
      • China Southeast
      • Hainan
    • Eastern Asia
      • Japan
      • Nansei-shoto
      • Taiwan

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000257052
Tropicos 50058517
KEW urn:lsid:ipni.org:names:758479-1
The Plant List kew-140419
Open Tree Of Life 394405
Observations.org 360892
NCBI Taxonomy 367363
IPNI 758479-1
iNaturalist 603383
GBIF 5340994
EPPO OPHJA
EOL 1102627
Elurikkus 521101
USDA GRIN 25793

Genomes (via NCBI) Top

Below is displayed the reference genome only!
If you wish to browse all genomes for this plant click here.
Accession Assembly
Name Level Submitter Released Coverage Size
GCA_051401725.1 GZNU_OpJapo_1.0 Chromosome Guizhou Normal University 2025-07-18 50.07 524.34 Mb

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Induction of Monoterpenoid Oxindole Alkaloids Production and Related Biosynthetic Gene Expression in Response to Signaling Molecules in Hamelia patens Plant Cultures López-Vázquez AL, Sepúlveda-García EB, Rubio-Rodríguez E, Ponce-Noyola T, Trejo-Tapia G, Barrera-Cortés J, Cerda-García-Rojas CM, Ramos-Valdivia AC Plants (Basel) 27-Mar-2024
PMCID:PMC11013434
doi:10.3390/plants13070966
PMID:38611495
Profiles of Metabolic Genes in Uncaria rhynchophylla and Characterization of the Critical Enzyme Involved in the Biosynthesis of Bioactive Compounds-(iso)Rhynchophylline Yang M, Yao B, Lin R Biomolecules 30-Nov-2022
PMCID:PMC9775700
doi:10.3390/biom12121790
PMID:36551218
Indole-Containing Natural Products 2019–2022: Isolations, Reappraisals, Syntheses, and Biological Activities Umer SM, Solangi M, Khan KM, Saleem RS Molecules 05-Nov-2022
PMCID:PMC9655573
doi:10.3390/molecules27217586
PMID:36364413
The S-Gene YUC6 Pleiotropically Determines Male Mating Type and Pollen Size in Heterostylous Turnera (Passifloraceae): A Novel Neofunctionalization of the YUCCA Gene Family Henning PM, Shore JS, McCubbin AG Plants (Basel) 08-Oct-2022
PMCID:PMC9572539
doi:10.3390/plants11192640
PMID:36235506
Structurally Diverse Metabolites from the Ophiorrhiza japonica Bl. and Their Antioxidant Activities In Vitro and PPARα Agonistic Activities In Silico Bu Q, Jin Y, Xu MJ, Wu L, Liang LF Molecules 19-Aug-2022
PMCID:PMC9412425
doi:10.3390/molecules27165301
PMID:36014541
Total Synthesis of Ophiorrhine A, G and Ophiorrhiside E Featuring a Bioinspired Intramolecular Diels–Alder Cycloaddition Cao W, Dou Y, Kouklovsky C, Vincent G Angew Chem Int Ed Engl 10-Aug-2022
PMCID:PMC9543224
doi:10.1002/anie.202209135
PMID:35869029
Recent studies on chemical constituents of Ophiorrhiza plants Kitajima M J Nat Med 28-Jul-2022
PMCID:PMC9411090
doi:10.1007/s11418-022-01640-3
PMID:35902551
Integrative analysis of transcriptome and metabolome reveals the effect of DNA methylation of chalcone isomerase gene in promoter region on Lithocarpus polystachyus Rehd flavonoids Lin L, Wang S, Zhang J, Song X, Zhang D, Cheng W, Cui M, Long Y, Xing Z Synth Syst Biotechnol 20-May-2022
PMCID:PMC9149025
doi:10.1016/j.synbio.2022.05.003
PMID:35664927
Plants and endophytes – a partnership for the coumarin production through the microbial systems Srinivasa C, Mellappa G, Patil SM, Ramu R, Shreevatsa B, Dharmashekar C, Kollur SP, Syed A, Shivamallu C Mycology 07-Feb-2022
PMCID:PMC9673776
doi:10.1080/21501203.2022.2027537
PMID:36405338
Functional analysis of a dihydroflavonol 4-reductase gene in Ophiorrhiza japonica (OjDFR1) reveals its role in the regulation of anthocyanin Sun W, Zhou N, Feng C, Sun S, Tang M, Tang X, Ju Z, Yi Y PeerJ 20-Oct-2021
PMCID:PMC8541326
doi:10.7717/peerj.12323
PMID:34721993
Traditional Chinese medicine in COVID-19 Lyu M, Fan G, Xiao G, Wang T, Xu D, Gao J, Ge S, Li Q, Ma Y, Zhang H, Wang J, Cui Y, Zhang J, Zhu Y, Zhang B Acta Pharm Sin B 20-Sep-2021
PMCID:PMC8450055
doi:10.1016/j.apsb.2021.09.008
PMID:34567957
LED Lights Promote Growth and Flavonoid Accumulation of Anoectochilus roxburghii and Are Linked to the Enhanced Expression of Several Related Genes Gam DT, Khoi PH, Ngoc PB, Linh LK, Hung NK, Anh PT, Thu NT, Hien NT, Khanh TD, Ha CH Plants (Basel) 12-Oct-2020
PMCID:PMC7599663
doi:10.3390/plants9101344
PMID:33053736
The Chalcone Isomerase Family in Cotton: Whole-Genome Bioinformatic and Expression Analyses of the Gossypium barbadense L. Response to Fusarium Wilt Infection Zu QL, Qu YY, Ni ZY, Zheng K, Chen Q, Chen QJ Genes (Basel) 04-Dec-2019
PMCID:PMC6947653
doi:10.3390/genes10121006
PMID:31817162
Chalcone Isomerase a Key Enzyme for Anthocyanin Biosynthesis in Ophiorrhiza japonica Sun W, Shen H, Xu H, Tang X, Tang M, Ju Z, Yi Y Front Plant Sci 09-Jul-2019
PMCID:PMC6629912
doi:10.3389/fpls.2019.00865
PMID:31338101
Comparison of Strategies to Overcome Drug Resistance: Learning from Various Kingdoms Ogawara H Molecules 18-Jun-2018
PMCID:PMC6100412
doi:10.3390/molecules23061476
PMID:29912169

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Harmala alkaloids
Harman 5281404 Click to see CC1=NC=CC2=C1NC3=CC=CC=C23 182.22 unknown https://doi.org/10.1248/YAKUSHI1947.87.9_1153
https://doi.org/10.1016/S0040-4039(00)95021-4
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides
(2S,3R,4S)-3-ethenyl-4-[(6-hydroxy-9H-pyrido[3,4-b]indol-1-yl)methyl]-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydro-2H-pyran-5-carboxylic acid 163188336 Click to see C=CC1C(C(=COC1OC2C(C(C(C(O2)CO)O)O)O)C(=O)O)CC3=NC=CC4=C3NC5=C4C=C(C=C5)O 528.50 unknown https://doi.org/10.1248/CPB.34.3064
3-ethenyl-4-(9H-pyrido[3,4-b]indol-1-ylmethyl)-2-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydro-2H-pyran-5-carboxylic acid 23757137 Click to see C=CC1C(C(=COC1OC2C(C(C(C(O2)CO)O)O)O)C(=O)O)CC3=NC=CC4=C3NC5=CC=CC=C45 512.50 unknown https://doi.org/10.1248/CPB.34.3064
Carboline metabolite (C26H28N2O10) 139292061 Click to see C=CC1C(C(=COC1OC2C(C(C(C(O2)CO)O)O)O)C(=O)O)CC3=NC=CC4=C3NC5=C4C=C(C=C5)O 528.50 unknown https://doi.org/10.1248/CPB.34.3064
Lyalosidic acid 10391678 Click to see 512.50 unknown https://doi.org/10.1248/CPB.34.3064
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
Friedelan-3-one 244297 Click to see 426.70 unknown https://doi.org/10.1248/YAKUSHI1947.87.9_1153
Friedelin 91472 Click to see 426.70 unknown https://doi.org/10.1248/YAKUSHI1947.87.9_1153
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(3S,8R,9R,10R,13R,14R,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 11870456 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown https://doi.org/10.1248/YAKUSHI1947.87.9_1153
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / O-glycosyl compounds
(-)-Sweroside 161036 Click to see 358.34 unknown https://doi.org/10.1016/0031-9422(88)87030-4
(3S,4R,4aS)-4-ethenyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,4a,5,6-tetrahydro-3H-pyrano[3,4-c]pyran-8-one 354447 Click to see 358.34 unknown https://doi.org/10.1016/0031-9422(88)87030-4
> Organoheterocyclic compounds / Indoles and derivatives / Pyridoindoles / Beta carbolines
17-Ethenyl-18-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-19-oxa-2,12-diazapentacyclo[14.3.1.02,14.05,13.06,11]icosa-3,5,7,9,11,13-hexaene-20-carboxylic acid 163192292 Click to see 512.50 unknown https://doi.org/10.1016/S0040-4039(00)95021-4

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