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Mitragyna parvifolia

Mitragyna parvifolia - Unknown
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Author: Public Domain - WikiMedia
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Table of Contents

Details
Description
Synonyms
Common Names
Subtypes (subspecies, varieties, subvarieties, forms)
Germination/Propagation
Distribution
Links to other databases
Genome
Scientific Literature
Phytochemical Profile
Biological Material
Contributors
Collections

Details Top

Internal ID UUID643fe38f10546948567097
Scientific name Mitragyna parvifolia
Authority Korth.
First published in Observ. Naucl. Indic. : 19 (1839)

Description Top

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Mitragyna parvifolia is a tree species native to India and Sri Lanka, reaching heights of 50 feet with a branch spread of 15 feet. Its leaves and stem bark have been traditionally used by various tribes for medicinal purposes, such as treating jaundice, pain, and fever. The tree also has religious significance, being associated with Lord Krishna in Vrindavana. Phytochemical analysis has revealed the presence of various alkaloids in M. parvifolia, making it a valuable plant for its medicinal properties. Additionally, the caterpillars of a butterfly species use this tree as a food source.

Synonyms Top

Scientific name Authority First published in
Nauclea parvifolia Roxb. Pl. Coromandel 1: 40 (1795)
Stephegyne parvifolia (Roxb.) Korth. Verh. Nat. Gesch. Ned. Bezitt., Bot. : 161 (1842)
Nauclea parvifolia var. diversifolia Kurz J. Asiat. Soc. Bengal 46(2): 127 1877

Common names Top

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Language Common/alternative name
Bengali কেলি কদম
Kannada ನೀರ ಕದಂಬ
Malayalam പൂച്ചക്കടമ്പ്
Tamil நீர்க்கடம்ப மரம்

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Name Authority First published in
Mitragyna parvifolia var. microphylla (Kurz) Ridsdale Blumea 24: 64 (1978)
Mitragyna parvifolia var. parvifolia Unknown

Subvarieties (abbr. subvar.) Top

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No subvariety added yet.

Forms (abbr. f.) Top

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No forms added yet.

Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-tropical
    • Indian Subcontinent
      • Bangladesh
      • India
      • Nepal
      • Sri Lanka
      • West Himalaya
    • Indo-China
      • Andaman Islands
      • Cambodia
      • Myanmar
      • Nicobar Nicobar

Links to other databases Top

Suggest others/fix!
Database ID/link to page
World Flora Online wfo-0000244938
Tropicos 27900206
KEW urn:lsid:ipni.org:names:756300-1
The Plant List kew-128800
Open Tree Of Life 830322
NCBI Taxonomy 1288021
IPNI 756300-1
iNaturalist 542917
GBIF 2900484
Freebase /m/0dyz82
EOL 1106503
USDA GRIN 312842
Wikipedia Mitragyna_parvifolia

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Induction of Monoterpenoid Oxindole Alkaloids Production and Related Biosynthetic Gene Expression in Response to Signaling Molecules in Hamelia patens Plant Cultures López-Vázquez AL, Sepúlveda-García EB, Rubio-Rodríguez E, Ponce-Noyola T, Trejo-Tapia G, Barrera-Cortés J, Cerda-García-Rojas CM, Ramos-Valdivia AC Plants (Basel) 27-Mar-2024
PMCID:PMC11013434
doi:10.3390/plants13070966
PMID:38611495
De novo biosynthesis of antiarrhythmic alkaloid ajmaline Guo J, Gao D, Lian J, Qu Y Nat Commun 11-Jan-2024
PMCID:PMC10784492
doi:10.1038/s41467-024-44797-z
PMID:38212296
Preliminary Evaluation of Lablab purpureus Phytochemicals for Anti-BoHV-1 Activity Using In Vitro and In Silico Approaches Bhat SS, Pradeep S, Patil SS, Flores-Holguín N, Glossman-Mitnik D, Frau J, Sommano SR, Ali N, Mohany M, Shivamallu C, Prasad SK, Kollur SP ACS Omega 14-Jun-2023
PMCID:PMC10308559
doi:10.1021/acsomega.3c01478
PMID:37396248
Comparative metabolomics analysis reveals alkaloid repertoires in young and mature Mitragyna speciosa (Korth.) Havil. Leaves Veeramohan R, Zamani AI, Azizan KA, Goh HH, Aizat WM, Razak MF, Yusof NS, Mansor SM, Baharum SN, Ng CL PLoS One 21-Mar-2023
PMCID:PMC10030037
doi:10.1371/journal.pone.0283147
PMID:36943850
Inventorization and Consensus Analysis of Ethnoveterinary Medicinal Knowledge Among the Local People in Eastern India: Perception, Cultural Significance, and Resilience Mandal SK, Rahaman CH Front Pharmacol 29-Apr-2022
PMCID:PMC9099233
doi:10.3389/fphar.2022.861577
PMID:35571138
In Vitro Propagation, Genetic Assessment, and Medium-Term Conservation of the Coastal Endangered Species Tetraclinis articulata (Vahl) Masters (Cupressaceae) from Adult Trees Juan-Vicedo J, Serrano-Martínez F, Cano-Castillo M, Casas JL Plants (Basel) 11-Jan-2022
PMCID:PMC8778163
doi:10.3390/plants11020187
PMID:35050075
The Adverse Cardiovascular Effects and Cardiotoxicity of Kratom (Mitragyna speciosa Korth.): A Comprehensive Review Leong Bin Abdullah MF, Singh D Front Pharmacol 27-Sep-2021
PMCID:PMC8504575
doi:10.3389/fphar.2021.726003
PMID:34646135
An improved micropropagation protocol for the ex situ conservation of Mitragyna parvifolia (Roxb.) Korth. (Rubiaceae): an endangered tree of pharmaceutical importance Patel AK, Lodha D, Shekhawat NS In Vitro Cell Dev Biol Plant 22-Jun-2020
PMCID:PMC7307943
doi:10.1007/s11627-020-10089-6
PMID:32837138
Efficacy and Mechanism of Traditional Medicinal Plants and Bioactive Compounds against Clinically Important Pathogens Mickymaray S Antibiotics (Basel) 09-Dec-2019
PMCID:PMC6963422
doi:10.3390/antibiotics8040257
PMID:31835403
Unnatural spirocyclic oxindole alkaloids biosynthesis in Uncaria guianensis Lopes AA, Chioca B, Musquiari B, Crevelin EJ, França SD, Fernandes da Silva MF, Pereira AM Sci Rep 05-Aug-2019
PMCID:PMC6683290
doi:10.1038/s41598-019-47706-3
PMID:31383908
Infrequent use of medicinal plants from India in snakebite treatment Upasani MS, Upasani SV, Beldar VG, Beldar CG, Gujarathi PP Integr Med Res 06-Nov-2017
PMCID:PMC5884010
doi:10.1016/j.imr.2017.10.003
PMID:29629287
Medicinal Plants for the Treatment of Local Tissue Damage Induced by Snake Venoms: An Overview from Traditional Use to Pharmacological Evidence Félix-Silva J, Silva-Junior AA, Zucolotto SM, Fernandes-Pedrosa MD Evid Based Complement Alternat Med 21-Aug-2017
PMCID:PMC5585606
doi:10.1155/2017/5748256
PMID:28904556
Leptadenia reticulata (Retz.) Wight & Arn. (Jivanti): Botanical, Agronomical, Phytochemical, Pharmacological, and Biotechnological Aspects Mohanty SK, Swamy MK, Sinniah UR, Anuradha M Molecules 19-Jun-2017
PMCID:PMC6152761
doi:10.3390/molecules22061019
PMID:28629185
Biochemical Benefits, Diagnosis, and Clinical Risks Evaluation of Kratom Fluyau D, Revadigar N Front Psychiatry 24-Apr-2017
PMCID:PMC5402527
doi:10.3389/fpsyt.2017.00062
PMID:28484399
Ethnomedicinal plants used for snakebite in India: a brief overview Upasani SV, Beldar VG, Tatiya AU, Upasani MS, Surana SJ, Patil DS Integr Med Res 20-Mar-2017
PMCID:PMC5478250
doi:10.1016/j.imr.2017.03.001
PMID:28664135

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Corynanthean-type alkaloids
18,19-Dihydrocorynantheine 5351579 Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=CC=CC=C34 368.50 unknown https://doi.org/10.1055/S-0028-1099827
methyl (Z)-2-[(2R,3S,12bR)-3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate 101358740 Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=CC=CC=C34 368.50 unknown https://doi.org/10.1055/S-0028-1099827
https://doi.org/10.1055/S-0028-1099568
Methyl 2-(3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyprop-2-enoate 415704 Click to see CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=CC=CC=C34 368.50 unknown https://doi.org/10.1055/S-0028-1099827
https://doi.org/10.1055/S-0028-1099568
> Alkaloids and derivatives / Yohimbine alkaloids
3-Isoajmalicine 11416867 Click to see CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=CC=CC=C45 352.40 unknown https://doi.org/10.1055/S-0028-1099932
Lamuran 251561 Click to see CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=CC=CC=C45 352.40 unknown https://doi.org/10.1055/S-0028-1099876
https://doi.org/10.1055/S-0028-1099827
https://doi.org/10.1055/S-0028-1099932
methyl (1R,15R,16R,20R)-16-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,18-pentaene-19-carboxylate 969486 Click to see CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=CC=CC=C45 352.40 unknown https://doi.org/10.1055/S-0028-1099827
methyl (1R,15R,16S,20R)-16-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,18-pentaene-19-carboxylate 7067845 Click to see CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=CC=CC=C45 352.40 unknown https://doi.org/10.1055/S-0028-1099876
https://doi.org/10.1055/S-0028-1099932
methyl (1S,3R,4R,4aR,5aS,6R,10aR)-3-hydroxy-1-methyl-2'-oxospiro[1,3,4,4a,5,5a,7,8,10,10a-decahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate 162997622 Click to see CC1C2CN3CCC4(C3CC2C(C(O1)O)C(=O)OC)C5=CC=CC=C5NC4=O 386.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.06.017
methyl (1S,3R,4R,4aS,5aS,6R,10aR)-3-hydroxy-1-methyl-2'-oxospiro[1,3,4,4a,5,5a,7,8,10,10a-decahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate 162997621 Click to see CC1C2CN3CCC4(C3CC2C(C(O1)O)C(=O)OC)C5=CC=CC=C5NC4=O 386.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.06.017
methyl (1S,3R,4R,4aS,5aS,6S,10aR)-3-hydroxy-1-methyl-2'-oxospiro[1,3,4,4a,5,5a,7,8,10,10a-decahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate 162997619 Click to see CC1C2CN3CCC4(C3CC2C(C(O1)O)C(=O)OC)C5=CC=CC=C5NC4=O 386.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.06.017
methyl 3-hydroxy-1-methyl-2'-oxospiro[1,3,4,4a,5,5a,7,8,10,10a-decahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate 162997618 Click to see CC1C2CN3CCC4(C3CC2C(C(O1)O)C(=O)OC)C5=CC=CC=C5NC4=O 386.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.06.017
> Organoheterocyclic compounds / Indoles and derivatives / Indoles / 3-alkylindoles
methyl (Z)-2-[(3R,6'S,7'R,8'aS)-6'-ethyl-4-hydroxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate 163187294 Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4O)NC3=O 400.50 unknown https://doi.org/10.1055/S-0028-1100162
methyl 2-(6'-ethyl-4-hydroxy-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl)-3-methoxyprop-2-enoate 634020 Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=C(C=CC=C4O)NC3=O 400.50 unknown https://doi.org/10.1055/S-0028-1100162
> Organoheterocyclic compounds / Indoles and derivatives / Pyridoindoles / Beta carbolines
(2S,3R,12bR)-3-ethenyl-2-[(E)-2-methoxyethenyl]-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine 163190324 Click to see COC=CC1CC2C3=C(CCN2CC1C=C)C4=CC=CC=C4N3 308.40 unknown https://doi.org/10.1055/S-0028-1099568
2-(3-Ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)ethanol 495273 Click to see CCC1CN2CCC3=C(C2CC1CCO)NC4=CC=CC=C34 298.40 unknown https://doi.org/10.1055/S-0028-1099465
3-Ethenyl-2-(2-methoxyethenyl)-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine 162967699 Click to see COC=CC1CC2C3=C(CCN2CC1C=C)C4=CC=CC=C4N3 308.40 unknown https://doi.org/10.1055/S-0028-1099568
Corynan-17-ol 164952 Click to see CCC1CN2CCC3=C(C2CC1CCO)NC4=CC=CC=C34 298.40 unknown https://doi.org/10.1055/S-0028-1099465
Corynantheidol 11044739 Click to see CCC1CN2CCC3=C(C2CC1CCO)NC4=CC=CC=C34 298.40 unknown https://doi.org/10.1055/S-0028-1099465
> Organoheterocyclic compounds / Indolizidines
(3R,20S)-19alpha-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester 98363 Click to see CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O 368.40 unknown https://doi.org/10.1055/S-0028-1099876
https://doi.org/10.1055/S-0028-1099827
https://doi.org/10.1016/J.PHYTOCHEM.2006.06.017
Isocorynoxeine 3037448 Click to see COC=C(C1CC2C3(CCN2CC1C=C)C4=CC=CC=C4NC3=O)C(=O)OC 382.50 unknown https://doi.org/10.1055/S-0028-1099568
Isomitraphylline 11726520 Click to see CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O 368.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.06.017
Isopteropodine 9885603 Click to see CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O 368.40 unknown https://doi.org/10.1055/S-0028-1099827
https://doi.org/10.1055/S-0028-1099876
methyl (Z)-2-[(3S,6'S,7'R,8'aR)-6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate 1245595 Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O 384.50 unknown https://doi.org/10.1055/S-0028-1099840
https://doi.org/10.1055/S-0028-1099827
https://doi.org/10.1055/S-0028-1100162
methyl 2-(6'-ethenyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl)-3-methoxyprop-2-enoate 73081505 Click to see COC=C(C1CC2C3(CCN2CC1C=C)C4=CC=CC=C4NC3=O)C(=O)OC 382.50 unknown https://doi.org/10.1055/S-0028-1099568
methyl 2-(6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl)-3-methoxyprop-2-enoate 409518 Click to see CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O 384.50 unknown https://doi.org/10.1055/S-0028-1099827
https://doi.org/10.1055/S-0028-1099840
https://doi.org/10.1055/S-0028-1100162
Mitraphylline 94160 Click to see CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O 368.40 unknown https://doi.org/10.1016/J.PHYTOCHEM.2006.06.017

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