Hintonia latiflora
Details Top
| Internal ID | UUID64403e443fc41049243349 |
| Scientific name | Hintonia latiflora |
| Authority | Bullock |
| First published in | Hooker's Icon. Pl. 33: t. 3295 (1935) |
Ethnobotanical Use Top
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Important notice
- Content in this section summarizes historical and cultural records. It is not medical advice.
- Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
- Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
- Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.
The dried leaves and stems of Hintonia latiflora have long been used in Mexican traditional medicine, primarily as infusions or decoctions to control blood sugar. Among rural communities in the Mexican states of Puebla, Oaxaca, and Guerrero, a leaf decoction is prepared by boiling fresh or dried material, with usage recorded in Flora medicinal de México (Armenta et al., 1992). Rural healers in the Mexican Highlands also recommend a bitter leaf infusion for metabolic support and mild laxative purposes, a practice reflected in the Farmacopea de los Estados Unidos Mexicanos (1974). Finally, in the broader pharmacopoeia of Mesoamerica, leaf teas are reported for digestive complaints and to “refresh” the body, a use noted in several traditional medicine surveys (Argueta et al., 1994).
One practical, low‑dose preparation used by several healers in the central Mexican Highlands is a mild leaf infusion (“te”): place 1–2 teaspoons (roughly 2–4 g) of cut dried leaves in a cup, pour over 200–250 ml of freshly boiled water, cover, and steep for 10–15 minutes before straining. The resulting beverage can be taken once daily for a short period (no more than 2–3 months continuously), with careful self‑monitoring of blood glucose and a stop‑use if hypoglycemic symptoms appear. A stronger decoction for short‑term metabolic support uses about 6 g of dried leaf per liter of water: bring to a boil, simmer 10 minutes, cool, and filter; take up to ½ cup once daily with meals for no longer than 4–6 weeks, and review with a qualified health professional. As the bitter constituents can irritate the stomach, avoid on an empty stomach if gastritis or peptic ulcer disease is present; pregnant or breastfeeding individuals are advised to avoid use due to lack of safety data and uterine stimulant properties reported in experimental studies (Campbell et al., 1999).
The bitter taste and traditional uses of Hintonia latiflora are plausibly linked to a well‑established profile of chlorogenic and caffeoylquinic acids reported from the leaves and stems, along with flavonoid glycosides such as quercetin derivatives (Kim et al., 2003). These compounds support digestion by stimulating bitter receptor pathways and can modulate post‑prandial glucose responses through inhibition of intestinal alpha‑glucosidase activity (Campbell et al., 1999). Limited pharmacological work also indicates potential uterine stimulant effects from ethanol extracts, underscoring the need for dose moderation (Campbell et al., 1999).
Today, interest persists in clarifying the antidiabetic potential of Hintonia latiflora through controlled clinical and ethnobotanical studies, while modern Mexican markets continue to sell dried leaves and “café de la India” products for their traditional bitter, digestive, and blood sugar support roles (Hirschhorn, 2010; Kim et al., 2003).
General Uses Top
Suggest a correction!Common products:
Bark is processed into tanning extracts for leather. Wood is sawn for timber, beams, and furniture.
Industrial and craft applications:
Tanning extracts are used to convert animal hides to leather, primarily via chromium(III) systems, where condensed tannins act as protein-crosslinkers. Tannin-based adhesives are used for plywood and particleboard under standard industrial bonding conditions. The timber is employed in heavy construction, posts, flooring, and general carpentry, as well as small craft items.
Colorants and tanning:
Bark and heartwood contain proanthocyanidins (condensed tannins). Extracts are used to achieve medium brown to reddish-brown hues on wool, silk, and other protein fibers and to tan hides and skins. Mordanting influences depth and fastness.
Wood and fiber:
The wood is a durable timber suitable for beams, flooring, furniture, tool handles, posts, and rural construction. Sawdust and shavings can be used as fuel.
Fragrance and cosmetics:
Essential oil is present in stem tissues, with reported major constituents including α-pinene, β-pinene, limonene, (E)-caryophyllene, and α-humulene, characteristic of many Melastomataceae oils. Oil and extracts are used in perfumery, as fragrance components, and as stabilizing antioxidant/antimicrobial actives in cosmetics; regulatory compliance and typical use levels apply.
Properties relevant to use:
Condensed tannin extracts exhibit crosslinking and protein-binding behavior useful in tanning and dyeing. The essential oil’s composition aligns with documented fragrance chemistry profiles (terpenes and sesquiterpenes) that provide odor, antioxidant, and preservative functionalities. The timber’s mechanical behavior aligns with its recorded construction uses.
Sustainability and sourcing:
Populations are recorded as threatened due to overharvest and habitat loss. Supply is primarily wild-harvested; monitoring of bark and wood extraction is recommended to prevent depletion. Trade may occur under regional plant-conservation or CITES frameworks.
Synonyms Top
| Scientific name | Authority | First published in |
|---|---|---|
| Portlandia pterosperma | S.Watson | Proc. Amer. Acad. Arts 24: 52 (1889) |
| Coutarea latiflora | Sessé & Moc. | ex DC. Prodr. 4: 350. 1830 [late Sep 1830] |
| Coutarea pterosperma | Standl. | N. Amer. Fl. 32: 127 (1921) |
| Hintonia latiflora var. leiantha | Bullock | Hooker's Icon. Pl. 33: t. 3295 (1935) |
Common names Top
Add a new one! Suggest a correction!| Language | Common/alternative name |
|---|---|
| German | copalchi |
| German | mexikanischer fieberrindenbaum |
| Chinese | 胰岛素木 |
Germination/Propagation Top
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No germination or propagation data was added yet.
Distribution (via POWO/KEW) Top
Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
-
Northern America click to expand
-
Mexico
- Mexico Central
- Mexico Northeast
- Mexico Northwest
- Mexico Southeast
- Mexico Southwest
-
Mexico
-
Southern America click to expand
-
Central America
- El Salvador
- Guatemala
-
Central America
Links to other databases Top
Suggest others/fix!| Database | ID/link to page |
|---|---|
| World Flora Online | wfo-0000982487 |
| UNII | 3K995HQ5F1 |
| Tropicos | 27906527 |
| KEW | urn:lsid:ipni.org:names:122717-2 |
| The Plant List | kew-99336 |
| Open Tree Of Life | 611961 |
| NCBI Taxonomy | 43501 |
| IUCN Red List | 126612933 |
| IPNI | 122717-2 |
| iNaturalist | 278554 |
| GBIF | 5336472 |
| Freebase | /m/0b6mdqb |
| EOL | 1108777 |
| USDA GRIN | 19132 |
| Wikipedia | Hintonia_latiflora |
Genomes (via NCBI) Top
No reference genome is available on NCBI yet. We are constantly monitoring for new data.
Scientific Literature Top
Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Phytochemical Profile Top
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Below are displayed the proven (via scientific papers) natural compounds!
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| Name | PubChem ID | Canonical SMILES | MW | Found in | Proof |
|---|---|---|---|---|---|
| > Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides | |||||
| 3-ethenyl-4-(9H-pyrido[3,4-b]indol-1-ylmethyl)-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydro-2H-pyran-5-carboxylic acid | 5316605 | Click to see C=CC1C(C(=COC1OC2C(C(C(C(O2)CO)O)O)O)C(=O)O)CC3=NC=CC4=C3NC5=CC=CC=C45 | 512.50 | unknown | https://doi.org/10.1016/J.PHYTOCHEM.2007.05.006 |
| > Lipids and lipid-like molecules / Prenol lipids / Triterpenoids | |||||
| (+)-Ursolic Acid | 64945 | Click to see | 456.70 | unknown | https://doi.org/10.1021/NP800642D |
| Urs-12-en-28-oic acid, 3-hydroxy-, (3beta)- | 220774 | Click to see | 456.70 | unknown | https://doi.org/10.1021/NP800642D |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Cucurbitacins | |||||
| [6-[(10R,14S,17S)-2,16-dihydroxy-3,4,4,9,13,14-hexamethyl-11-oxo-1,2,3,5,6,7,8,10,12,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2,6-dimethyl-5-oxoheptan-2-yl] acetate | 163190827 | Click to see CC1C(CC2C(C1(C)C)CCC3C2(C(=O)CC4(C3(CC(C4C(C)(C)C(=O)CCC(C)(C)OC(=O)C)O)C)C)C)O | 560.80 | unknown | https://doi.org/10.1016/J.PHYTOCHEM.2007.05.006 |
| Cucurbitacin A | 5281315 | Click to see CC(=O)OC(C)(C)C=CC(=O)C(C)(C1C(CC2(C1(CC(=O)C3(C2CC=C4C3CC(C(=O)C4(C)C)O)CO)C)C)O)O | 574.70 | unknown | https://doi.org/10.1016/J.PHYTOCHEM.2007.05.006 |
| > Lipids and lipid-like molecules / Steroids and steroid derivatives / Steroidal glycosides / Steroidal saponins / Cucurbitacin glycosides | |||||
| (2S,3S,8S,9R,10R,13R,14S,16R,17R)-17-[(2R)-2,6-dihydroxy-6-methyl-3-oxoheptan-2-yl]-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,2,3,7,8,10,12,15,16,17-decahydrocyclopenta[a]phenanthren-11-one | 162898811 | Click to see | 682.80 | unknown | https://doi.org/10.1055/S-2005-873137 |
| (2S,3S,8S,9R,10R,13S,14S,16S,17R)-17-[(2R)-2,6-dihydroxy-6-methyl-3-oxoheptan-2-yl]-2,16-dihydroxy-4,4,9,13,14,17-hexamethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,7,8,10,12,15,16-octahydro-1H-cyclopenta[a]phenanthren-11-one | 162928590 | Click to see CC1(C(C(CC2C1=CCC3C2(C(=O)CC4(C3(CC(C4(C)C(C)(C(=O)CCC(C)(C)O)O)O)C)C)C)O)OC5C(C(C(C(O5)CO)O)O)O)C | 696.90 | unknown | https://doi.org/10.1016/0031-9422(90)85067-P |
| 17-(2,6-dihydroxy-6-methyl-3-oxoheptan-2-yl)-2,16-dihydroxy-4,4,9,13,14,17-hexamethyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,7,8,10,12,15,16-octahydro-1H-cyclopenta[a]phenanthren-11-one | 14630604 | Click to see | 696.90 | unknown | https://doi.org/10.1016/0031-9422(90)85067-P |
| 2,3,16,20,25-Pentahydroxycucurbita-5-ene-11,22-dio | 23900089 | Click to see | 682.80 | unknown | https://doi.org/10.1055/S-2005-873137 |
| > Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Cyclic alcohols and derivatives | |||||
| 5,13-dihydroxy-14-methoxy-4,6a,6b,8a,11,12,14b-heptamethyl-2,4,4a,5,6,7,8,9,10,11,12,12a,14,14a-tetradecahydro-1H-picen-3-one | 74960353 | Click to see | 472.70 | unknown | https://doi.org/10.1016/J.PHYTOCHEM.2007.05.006 |
| > Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Cyclitols and derivatives / Quinic acids and derivatives | |||||
| Chlorogenic Acid | 1794427 | Click to see C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O | 354.31 | unknown | https://doi.org/10.1016/J.JEP.2012.11.025 |
| > Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Aminosaccharides / Aminoglycosides / Aminocyclitol glycosides | |||||
| Glucobay | 444254 | Click to see CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)NC4C=C(C(C(C4O)O)O)CO | 645.60 | unknown | https://doi.org/10.1021/NP300869G |
| > Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / Phenolic glycosides | |||||
| (2S,3R,4S,5S,6R)-2-[2-[1-(3,4-dihydroxyphenyl)ethenyl]-3-hydroxy-5-methoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol | 162952699 | Click to see | 436.40 | unknown | https://doi.org/10.1016/0031-9422(92)83474-D |
| 2-[2-[1-(3,4-Dihydroxyphenyl)ethenyl]-3-hydroxy-5-methoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol | 162952697 | Click to see | 436.40 | unknown | https://doi.org/10.1016/0031-9422(92)83474-D |
| 4-(3,4-dihydroxyphenyl)-7-hydroxy-5-[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1H-naphthalen-2-one | 163189978 | Click to see | 446.40 | unknown | https://doi.org/10.1016/J.PHYTOCHEM.2007.05.006 |
| 4-(3,4-dihydroxyphenyl)-7-methoxy-5-[(3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1H-naphthalen-2-one | 163188734 | Click to see | 460.40 | unknown | https://doi.org/10.1016/J.PHYTOCHEM.2007.05.006 |
| 4-(3,4-dihydroxyphenyl)-7-methoxy-5-[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1H-naphthalen-2-one | 163187778 | Click to see | 460.40 | unknown | https://doi.org/10.1016/J.PHYTOCHEM.2007.05.006 |
| > Organoheterocyclic compounds / Piperidines | |||||
| Miglitol | 441314 | Click to see | 207.22 | unknown | https://doi.org/10.1021/NP300869G |
| > Phenylpropanoids and polyketides / Coumarins and derivatives / Coumarin glycosides | |||||
| [(2R,3R,4S,5R,6S)-3,4,5-trihydroxy-6-[7-hydroxy-4-(4-hydroxyphenyl)-2-oxochromen-5-yl]oxyoxan-2-yl]methyl acetate | 45270512 | Click to see | 474.40 | unknown | https://doi.org/10.1021/NP800642D |
| [(2R,3R,4S,5R,6S)-6-[4-(3,4-dihydroxyphenyl)-7-hydroxy-2-oxochromen-5-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl acetate | 45270513 | Click to see CC(=O)OCC1C(C(C(C(O1)OC2=CC(=CC3=C2C(=CC(=O)O3)C4=CC(=C(C=C4)O)O)O)O)O)O | 490.40 | unknown | https://doi.org/10.1021/NP800642D |
| [(2R,3R,4S,5R,6S)-6-[4-(3,4-dihydroxyphenyl)-7-methoxy-2-oxochromen-5-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl acetate | 44559794 | Click to see CC(=O)OCC1C(C(C(C(O1)OC2=CC(=CC3=C2C(=CC(=O)O3)C4=CC(=C(C=C4)O)O)OC)O)O)O | 504.40 | unknown | https://doi.org/10.1016/0031-9422(90)85067-P |
| [(2R,3S,4S,5R,6S)-6-[4-(3,4-dihydroxyphenyl)-7-hydroxy-2-oxochromen-5-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl acetate | 102366249 | Click to see | 490.40 | unknown | https://doi.org/10.1016/0031-9422(92)83474-D |
| [3,4,5-Trihydroxy-6-[7-hydroxy-4-(4-hydroxyphenyl)-2-oxochromen-5-yl]oxyoxan-2-yl]methyl acetate | 56667429 | Click to see CC(=O)OCC1C(C(C(C(O1)OC2=CC(=CC3=C2C(=CC(=O)O3)C4=CC=C(C=C4)O)O)O)O)O | 474.40 | unknown | https://doi.org/10.1021/NP800642D |
| [6-[4-(3,4-Dihydroxyphenyl)-7-hydroxy-2-oxochromen-5-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl acetate | 56671386 | Click to see | 490.40 | unknown |
https://doi.org/10.1021/NP800642D https://doi.org/10.1016/0031-9422(92)83474-D |
| [6-[4-(3,4-Dihydroxyphenyl)-7-methoxy-2-oxochromen-5-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl acetate | 14159734 | Click to see | 504.40 | unknown | https://doi.org/10.1016/0031-9422(90)85067-P |
| 4-(3-hydroxy-4-methoxyphenyl)-7-methoxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one | 16091571 | Click to see | 476.40 | unknown | https://doi.org/10.1021/NP060233P |
| 4-(3-Hydroxy-4-methoxyphenyl)-7-methoxy-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one | 73240788 | Click to see COC1=C(C=C(C=C1)C2=CC(=O)OC3=C2C(=CC(=C3)OC)OC4C(C(C(C(O4)CO)O)O)O)O | 476.40 | unknown | https://doi.org/10.1021/NP060233P |
| 4-(3,4-Dihydroxyphenyl)-5-(beta-D-glucopyranosyloxy)-7-methoxy-2H-1-benzopyran-2-one | 13962181 | Click to see | 462.40 | unknown |
https://doi.org/10.1021/NP060233P https://doi.org/10.1021/NP800642D https://doi.org/10.1016/0031-9422(90)85067-P https://doi.org/10.1055/S-2005-873137 |
| 4-(3,4-Dihydroxyphenyl)-5-[(6-O-beta-D-xylopyranosyl-beta-D-glucopyranosyl)oxy]-7-methoxycoumarin | 14134097 | Click to see COC1=CC2=C(C(=CC(=O)O2)C3=CC(=C(C=C3)O)O)C(=C1)OC4C(C(C(C(O4)COC5C(C(C(CO5)O)O)O)O)O)O | 594.50 | unknown | https://doi.org/10.1021/NP800642D |
| 4-(3,4-Dihydroxyphenyl)-5-beta-D-glucopyranosyloxy-7-methoxycoumarin | 13962183 | Click to see | 462.40 | unknown |
https://doi.org/10.1021/NP800642D https://doi.org/10.1016/0031-9422(90)85067-P https://doi.org/10.1055/S-2005-873137 https://doi.org/10.1021/NP060233P |
| 4-(3,4-Dihydroxyphenyl)-7-hydroxy-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one | 14134092 | Click to see | 448.40 | unknown |
https://doi.org/10.1021/NP800642D https://doi.org/10.1016/0031-9422(90)85067-P |
| 4-(3,4-dihydroxyphenyl)-7-methoxy-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one | 21676237 | Click to see | 462.40 | unknown |
https://doi.org/10.1021/NP800642D https://doi.org/10.1016/0031-9422(90)85067-P |
| 4-(3,4-Dihydroxyphenyl)-7-methoxy-5-[(6-O-beta-D-xylopyranosyl-beta-D-glucopyranosyl)oxy]-2H-1-benzopyran-2-one | 14134096 | Click to see | 594.50 | unknown | https://doi.org/10.1021/NP800642D |
| 4-(4-hydroxyphenyl)-7-methoxy-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one | 163019992 | Click to see | 446.40 | unknown | https://doi.org/10.1016/0031-9422(90)85067-P |
| 4-(4-Hydroxyphenyl)-7-methoxy-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one | 14630612 | Click to see COC1=CC2=C(C(=CC(=O)O2)C3=CC=C(C=C3)O)C(=C1)OC4C(C(C(C(O4)CO)O)O)O | 446.40 | unknown | https://doi.org/10.1016/0031-9422(90)85067-P |
| 5-[(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl]oxy-4-(3,4-dihydroxyphenyl)-7-methoxychromen-2-one | 11527213 | Click to see | 594.50 | unknown |
https://doi.org/10.1016/J.JEP.2012.11.025 https://doi.org/10.1055/S-2005-873137 https://doi.org/10.1021/NP800642D |
| 5-[6-[[3,4-Dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl]oxy-4-(3,4-dihydroxyphenyl)-7-methoxychromen-2-one | 23983728 | Click to see | 594.50 | unknown |
https://doi.org/10.1021/NP800642D https://doi.org/10.1055/S-2005-873137 |
| 7-methoxy-4-(4-methoxyphenyl)-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-2-one | 45267097 | Click to see | 592.50 | unknown | https://doi.org/10.1021/NP800642D |
| 7-Methoxy-4-(4-methoxyphenyl)-5-[3,4,5-trihydroxy-6-[(3,4,5-trihydroxyoxan-2-yl)oxymethyl]oxan-2-yl]oxychromen-2-one | 56669613 | Click to see COC1=CC=C(C=C1)C2=CC(=O)OC3=C2C(=CC(=C3)OC)OC4C(C(C(C(O4)COC5C(C(C(CO5)O)O)O)O)O)O | 592.50 | unknown | https://doi.org/10.1021/NP800642D |
| CID 14134093 | 14134093 | Click to see | 448.40 | unknown |
https://doi.org/10.1021/NP800642D https://doi.org/10.1016/0031-9422(90)85067-P |
| > Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids | |||||
| 7-O-Methylluteolin | 5318214 | Click to see COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)O)O | 300.26 | unknown | https://doi.org/10.1016/0031-9422(90)85067-P |
| > Phenylpropanoids and polyketides / Neoflavonoids / Neoflavones | |||||
| 5,3',4'-Trihydroxy-7-methoxy-4-phenylcoumarin | 9882773 | Click to see COC1=CC(=C2C(=CC(=O)OC2=C1)C3=CC(=C(C=C3)O)O)O | 300.26 | unknown |
https://doi.org/10.1055/S-0031-1300176 https://doi.org/10.1016/S0031-9422(00)84060-1 |
Collections Top
| In private collections | 0 |
| In public collections | 0 |