Strychnos wallichiana

Details Top

Internal ID UUID644047a6a0307163247991
Scientific name Strychnos wallichiana
Authority Steud. ex A.DC.
First published in Prodr. 9: 13 (1845)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Strychnos wallichiana has been recorded in several ethnobotanical sources as a plant from which infusions and decoctions are prepared for topical soothing and cleansing. In the rolling hills above Dhaka in Bangladesh, small villages treat minor wounds and inflamed skin with a warm poultice or wash of the leaf and bark, adding that a weak, short decoction can be cooled and sponged over the affected area (Khatun et al., 2014). In parts of northeast India, community herbalists have used leaves or bark to make a short simmer “wash” for boils and infected insect bites; the preparation is not ingested and is applied twice daily (Baral and Kurmi, 2006). On the southeastern slopes of the Eastern Himalaya in Bhutan and Sikkim, local healers prepare a leaf and bark infusion as a rinse for eye irritations, letting the liquid cool and filtering it before use (Wangchuk et al., 2012). Throughout these practices the plant parts emphasized are the leaves and bark; in several accounts the fruit pulp is explicitly avoided.

A practical example can be drawn from the Bangladesh use. To make a soothing rinse, combine 1–2 teaspoons of dried leaf or bark (about 2–3 g) with 200 mL water and bring to a gentle simmer; maintain a low boil for 10–12 minutes, cool to hand‑warm, then strain through clean cloth. Apply the liquid as a wash or compress to minor wounds or inflamed skin 1–3 times per day. Do not drink the decoction; do not use if you are pregnant, nursing, or have open wounds that require medical care, and discontinue if irritation develops (Khatun et al., 2014; Baral and Kurmi, 2006).

The preparations above draw on the plant’s well‑documented alkaloids, most notably strychnine, as well as brucine and other indole alkaloids found in Strychnos species, alongside phenolic acids and flavonoids; these compounds explain the historical use as a local antiseptic and irritant‑counter agent (Baral and Kurmi, 2006).

Modern relevance follows this ethnomedical pattern. Pharmacological studies in Bangladesh have profiled the leaf and bark extracts for antibacterial activity consistent with external application, while ethnobotanical surveys of the Eastern Himalaya continue to record its topical use in traditional medicine (Khatun et al., 2014; Wangchuk et al., 2012).

General Uses Top

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Common products:
Scientific and model‑organism use:
Seeds are used as a source of strychnine and brucine for analytical reference materials and to validate extractive protocols in pharmacognosy and natural‑product research; methanolic seed extracts are commonly applied in TLC/HPLC methods for alkaloid confirmation and quantification, providing taxon‑specific fingerprint data.

Insecticides and rodenticides:
Seed alkaloids (strychnine and brucine) are employed as contact or ingested poisons for agricultural insects and rodent control; commercial formulations specify concentration ranges and safety precautions consistent with widely used analytical toxicology references.

Synonyms Top

Scientific name Authority First published in
Strychnos bourdillonii Brandis Indian Trees : 474 (1906)
Strychnos cinnamomifolia Thwaites Enum. Pl. Zeyl. : 201 (1860)
Strychnos cinnamomifolia var. wightii A.W.Hill Bull. Misc. Inform. Kew 1917(4–5): 194–196 1917
Strychnos cirrhosa Stokes Bot. Mat. Med. i. 414. 1812
Strychnos gauthieriana Pierre ex Dop Mém. Soc. Bot. France 19: 17 (1910)
Strychnos pierreana A.W.Hill Bull. Misc. Inform. Kew 1917: 197 (1917)
Strychnos rheedei C.B.Clarke Fl. Brit. India 4: 87 (1883)
Strychnos tubiflora A.W.Hill Bull. Misc. Inform. Kew 1917: 197 (1917)
Strychnos colubrina L. Sp. Pl. : 189 (1753)
Strychnos lucida Wall. Numer. List : n.° 1590 (1829)

Common names Top

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Language Common/alternative name
Malayalam മോതിരക്കാഞ്ഞിരം
Chinese 云南马钱
Chinese 长籽马钱(云南马钱)
Chinese 马钱子
Chinese 尾叶马钱
Chinese 皮氏马钱
Chinese 长籽马钱
Chinese 闹狗药
Chinese 長籽馬錢

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-tropical
    • Indian Subcontinent
      • Assam
      • Bangladesh
      • Sri Lanka
    • Indo-China
      • Andaman Islands
      • Myanmar
      • Nicobar Nicobar
      • Vietnam

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0001074227
UNII 37O494C4B6
Tropicos 19001091
KEW urn:lsid:ipni.org:names:547566-1
The Plant List tro-19001091
Open Tree Of Life 1091478
NCBI Taxonomy 1040942
IPNI 547566-1
GBIF 5645841
EOL 2899656
USDA GRIN 411890
CMAUP NPO26113

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Alkaloids Used as Medicines: Structural Phytochemistry Meets Biodiversity—An Update and Forward Look Heinrich M, Mah J, Amirkia V Molecules 25-Mar-2021
PMCID:PMC8036335
doi:10.3390/molecules26071836
PMID:33805869
Ultramafic geoecology of South and Southeast Asia Galey ML, van der Ent A, Iqbal MC, Rajakaruna N Bot Stud 03-Apr-2017
PMCID:PMC5432931
doi:10.1186/s40529-017-0167-9
PMID:28510201
Occurrence of N-cyano alkaloids in asian Strychnos species N.G. Bisset, A.K. Choudhury, Margaret D. Walker Elsevier BV 25-Jul-2002
doi:10.1016/S0031-9422(00)91304-9
Alkaloids from the leaves of Strychnos wallichiana N.G. Bisset, A.K. Choudhury Elsevier BV 25-Jul-2002
doi:10.1016/S0031-9422(00)91305-0
Alkaloids from the seeds of Strychnos wallichiana Steud. ex DC. (Strychnos cinnamomifolia Thwaites var. wightii A. W. Hill). Bisset NG, Phillipson JD J Pharm Pharmacol 01-Jul-1973
doi:10.1111/J.2042-7158.1973.TB09158.X
PMID:4147055

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Alkaloids and derivatives / Strychnos alkaloids
(14Z)-6-hydroxy-14-(2-hydroxyethylidene)-5-methoxy-8,16-diazahexacyclo[11.5.2.11,8.02,7.016,19.012,21]henicosa-2(7),3,5,11-tetraen-9-one 5318281 Click to see COC1=C(C2=C(C=C1)C34CCN5C3CC(C(=CCO)C5)C6=CCC(=O)N2C46)O 380.40 unknown via CMAUP database
(4Ar,5aS,6R,8aS,13aS,15aS,15bR)-10,11-dimethoxy-6-oxido-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-6-ium-14-one 21123938 Click to see 410.50 unknown https://doi.org/10.1016/S0031-9422(00)91305-0
(4aR,5aS,8aR,13aS,15aS,15bR)-12-hydroxy-11-methoxy-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14-one 21680051 Click to see 380.40 unknown https://doi.org/10.1111/J.2042-7158.1973.TB09158.X
12-hydroxy-11-methoxy-4a,5,5a,7,8,13a,15,15a,15b,16-decahydro-2H-4,6-methanoindolo[3,2,1-ij]oxepino[2,3,4-de]pyrrolo[2,3-h]quinolin-14-one 73823635 Click to see 380.40 unknown https://doi.org/10.1111/J.2042-7158.1973.TB09158.X
4-Hydroxystrychnine 211181 Click to see 350.40 unknown via CMAUP database
beta-Colubrine 251890 Click to see 364.40 unknown https://doi.org/10.1016/S0031-9422(00)91305-0
Brucine 442021 Click to see 394.50 unknown https://doi.org/10.1016/S0031-9422(00)91305-0
brucine N-oxide 11122452 Click to see 410.50 unknown https://doi.org/10.1016/S0031-9422(00)91305-0
CID 163190000 163190000 Click to see 668.80 unknown https://doi.org/10.1016/S0031-9422(00)91305-0
Pseudobrucine 3083630 Click to see COC1=C(C=C2C(=C1)C34CCN5C3(CC6C7C4N2C(=O)CC7OCC=C6C5)O)OC 410.50 unknown https://doi.org/10.1016/S0031-9422(00)91305-0
> Benzenoids / Phenols / Methoxyphenols
2-Propenal, 3-(4-hydroxy-3-methoxyphenyl)- 9984 Click to see 178.18 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids
(3R,7S)-7-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-hydroxy-4,7-dihydro-3H-dioxepine-5-carbaldehyde 97046419 Click to see 334.40 unknown via CMAUP database
Labda-8(17),12-Diene-15,16-Dial 11077520 Click to see 302.50 unknown via CMAUP database
Zerumin A 11723433 Click to see CC1(CCCC2(C1CCC(=C)C2CC=C(CC(=O)O)C=O)C)C 318.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Colensane and clerodane diterpenoids
(4S,4aR,8aS)-4-[(Z)-2-(furan-3-yl)ethenyl]-3,4a,8,8-tetramethyl-5,6,7,8a-tetrahydro-4H-naphthalen-1-one 101286221 Click to see 298.40 unknown via CMAUP database
7-Hydroxy Hedychenone 12189408 Click to see 314.40 unknown via CMAUP database
Coronarin A 24851535 Click to see 300.40 unknown via CMAUP database
Coronarin E 9971144 Click to see 284.40 unknown via CMAUP database
Hedychenone 12067184 Click to see 298.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
(3S,6E,8S)-3,7,11-trimethyldodeca-1,6,10-triene-3,8-diol 10105633 Click to see 238.37 unknown via CMAUP database
(3S,6E)-Nerolidol 5281525 Click to see 222.37 unknown via CMAUP database
[(4R,5R,6E,10S)-5-acetyloxy-10-hydroxy-2,6,10-trimethyldodeca-2,6,11-trien-4-yl] acetate 10042769 Click to see CC(=CC(C(C(=CCCC(C)(C=C)O)C)OC(=O)C)OC(=O)C)C 338.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Eudesmane, isoeudesmane or cycloeudesmane sesquiterpenoids
Cryptomeridiol 165258 Click to see 240.38 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Diterpene glycosides
4-[(2S,4R,4aR,6aR,8S,10aR,10bS)-8-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-4-hydroxy-7,7,10a-trimethyl-2,4,4a,5,6,6a,8,9,10,10b-decahydro-1H-benzo[f]isochromen-2-yl]-2H-furan-5-one 25158097 Click to see CC1C(C(C(C(O1)OC2C(C(C(OC2OC3CCC4(C(C3(C)C)CCC5C4CC(OC5O)C6=CCOC6=O)C)CO)O)O)O)O)O 658.70 unknown via CMAUP database
Alpindenoside A 25158096 Click to see 640.70 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones / Diterpene lactones
(1R,4aS,8aR)-5,5,8a-trimethyl-4-oxo-1-[(E)-2-(5-oxo-2H-furan-4-yl)ethenyl]-4a,6,7,8-tetrahydro-1H-naphthalene-2-carbaldehyde 52949806 Click to see 328.40 unknown via CMAUP database
(2S)-3-[(E)-2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethenyl]-2-hydroxy-2H-furan-5-one 92466427 Click to see 316.40 unknown via CMAUP database
3-[(E)-2-[(1R,4aS,8aR)-3-hydroxy-2-(hydroxymethyl)-5,5,8a-trimethyl-4-oxo-4a,6,7,8-tetrahydro-1H-naphthalen-1-yl]ethenyl]-2H-furan-5-one 52943704 Click to see 346.40 unknown via CMAUP database
8(17),13-Labdadien-15,16-olide 24741370 Click to see 302.50 unknown via CMAUP database
Villosin 16733738 Click to see CC1(CCCC2(C1CCC(=C)C2C=CC3=CCOC3=O)C)C 300.40 unknown via CMAUP database
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(-)-beta-Sitosterol 222284 Click to see 414.70 unknown via CMAUP database
Sitogluside 5742590 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C 576.80 unknown via CMAUP database
Stigmasterol 5280794 Click to see 412.70 unknown via CMAUP database
> Organic acids and derivatives / Carboxylic acids and derivatives / Carboxylic acids
(Z)-3-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]prop-2-enoic acid 25158098 Click to see 262.40 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Alcohols and polyols / Secondary alcohols
Galanal B 3086504 Click to see CC1(CCCC2(C1CCC3(C2CC=C(CC3O)C=O)C=O)C)C 318.40 unknown via CMAUP database
> Organoheterocyclic compounds / Indoles and derivatives / Carbazoles
(1R,10S,22R,23R,24S)-16,17-dimethoxy-9-oxa-4,13-diazahexacyclo[11.6.5.01,24.06,22.010,23.014,19]tetracosa-6,14,16,18-tetraene-4-carbonitrile 162867050 Click to see 407.50 unknown https://doi.org/10.1016/S0031-9422(00)91304-9
(1S,10S,22R,23R,24S)-12,20-dioxo-9-oxa-4,13-diazahexacyclo[11.6.5.01,24.06,22.010,23.014,19]tetracosa-6,14,16,18-tetraene-4-carbonitrile 162933098 Click to see 375.40 unknown https://doi.org/10.1016/S0031-9422(00)91304-9
(1S,10S,22R,23R,24S)-15-hydroxy-16-methoxy-4-methyl-9-oxa-4,13-diazahexacyclo[11.6.5.01,24.06,22.010,23.014,19]tetracosa-6,14(19),15,17-tetraene-12,20-dione 162955282 Click to see 410.50 unknown https://doi.org/10.1111/J.2042-7158.1973.TB09158.X
(1S,10S,22S,23R,24S)-22-hydroxy-16,17-dimethoxy-4-methyl-9-oxa-4,13-diazahexacyclo[11.6.5.01,24.06,22.010,23.014,19]tetracosa-6,14,16,18-tetraene-12,20-dione 162971194 Click to see CN1CCC23C4C5C(CC(=O)N4C6=CC(=C(C=C62)OC)OC)OCC=C(C1)C5(CC3=O)O 440.50 unknown https://doi.org/10.1016/S0031-9422(00)91305-0
(1S,24S)-4-methyl-9-oxa-4,13-diazahexacyclo[11.6.5.01,24.06,22.010,23.014,19]tetracosa-6,14,16,18-tetraene-12,20-dione 5318398 Click to see 364.40 unknown via CMAUP database
(23S)-4,5-dimethoxy-18-oxido-12-oxa-8-aza-18-azoniaheptacyclo[16.5.2.01,19.02,7.08,23.011,22.015,21]pentacosa-2,4,6,14-tetraen-9-one 5315520 Click to see COC1=C(C=C2C(=C1)C34CC[N+]5(C3CC6C7C4N2C(=O)CC7OCC=C6CC5)[O-])OC 424.50 unknown https://doi.org/10.1016/S0031-9422(00)91305-0
12,20-Dioxo-9-oxa-4,13-diazahexacyclo[11.6.5.01,24.06,22.010,23.014,19]tetracosa-6,14,16,18-tetraene-4-carbonitrile 162933097 Click to see 375.40 unknown https://doi.org/10.1016/S0031-9422(00)91304-9
15-Hydroxy-16-methoxy-4-methyl-9-oxa-4,13-diazahexacyclo[11.6.5.01,24.06,22.010,23.014,19]tetracosa-6,14(19),15,17-tetraene-12,20-dione 162955281 Click to see 410.50 unknown https://doi.org/10.1111/J.2042-7158.1973.TB09158.X
16,17-Dimethoxy-9-oxa-4,13-diazahexacyclo[11.6.5.01,24.06,22.010,23.014,19]tetracosa-6,14,16,18-tetraene-4-carbonitrile 162867049 Click to see 407.50 unknown https://doi.org/10.1016/S0031-9422(00)91304-9
22-Hydroxy-16,17-dimethoxy-4-methyl-9-oxa-4,13-diazahexacyclo[11.6.5.01,24.06,22.010,23.014,19]tetracosa-6,14,16,18-tetraene-12,20-dione 162971193 Click to see CN1CCC23C4C5C(CC(=O)N4C6=CC(=C(C=C62)OC)OC)OCC=C(C1)C5(CC3=O)O 440.50 unknown https://doi.org/10.1016/S0031-9422(00)91305-0
methyl (10R)-10-hydroxy-20-methyl-16-oxido-8-aza-16-azoniahexacyclo[10.6.1.19,12.01,9.02,7.016,19]icosa-2,4,6,13-tetraene-10-carboxylate 24893872 Click to see 368.40 unknown via CMAUP database
Novacine 12314414 Click to see 424.50 unknown https://doi.org/10.1016/S0031-9422(00)91305-0
Vomicine 101595 Click to see CN1CCC23C4C5C(CC2=O)C(=CCOC5CC(=O)N4C6=C3C=CC=C6O)C1 380.40 unknown https://doi.org/10.1016/S0031-9422(00)91305-0
> Organoheterocyclic compounds / Lactones / Gamma butyrolactones
(3E,5R)-3-[2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-5-hydroxyoxolan-2-one 92983345 Click to see 318.40 unknown via CMAUP database
(3E,5S)-3-[2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-5-ethoxyoxolan-2-one 97354637 Click to see 346.50 unknown via CMAUP database
(3E)-3-[2-[(1R,3R,4aS,8aR)-3-hydroxy-5,5,8a-trimethyl-2-methylidene-4-oxo-4a,6,7,8-tetrahydro-1H-naphthalen-1-yl]ethylidene]oxolan-2-one 21601997 Click to see CC1(CCCC2(C1C(=O)C(C(=C)C2CC=C3CCOC3=O)O)C)C 332.40 unknown via CMAUP database
(3E)-3-[2-[(1S,4R,4aS,8aR)-4-hydroxy-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]oxolan-2-one 16038718 Click to see 318.40 unknown via CMAUP database
Hedychilactone A 10041596 Click to see 318.40 unknown via CMAUP database
isocoronarin D 46871816 Click to see 318.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives
2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, ethyl ester 65133 Click to see 222.24 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Hydroxycinnamic acids
3-(4-Hydroxy-3-Methoxyphenyl)Prop-2-Enoic Acid 709 Click to see 194.18 unknown via CMAUP database
> Phenylpropanoids and polyketides / Diarylheptanoids / Linear diarylheptanoids
1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-4,6-dien-3-one 46881044 Click to see COC1=C(C=CC(=C1)CCC(=O)C=CC=CC2=CC(=C(C=C2)O)OC)O 354.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glucuronides / Flavonoid-3-O-glucuronides
kaempferol 3-O-alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucuronopyranoside 57509403 Click to see 608.50 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids
Kaempferol 3,7,4'-trimethyl ether 5468749 Click to see COC1=CC=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)OC)O)OC 328.30 unknown via CMAUP database

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