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Internal ID UUID643fea6ebc223546268748
Scientific name Aspidosperma olivaceum
Authority Müll.Arg.
First published in Fl. Bras. 6(1): 57 (1860)

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Synonyms Top

Scientific name Authority First published in
Macaglia olivacea (Müll.Arg.) Kuntze Revis. Gen. Pl. 2: 416 (1891)
Aspidosperma bello-horizontinum Silveira Arq. Mus. Nac. Rio de Janeiro 23: 159 (1921)
Aspidosperma sellowii Müll.Arg. Fl. Bras. 6(1): 56 (1860)
Thyroma sellowii Miers Apocyn. S. Amer. : 24 (1878)
Aspidosperma olivaceum var. obtusifolium Müll.Arg. Fl. Bras. 6(1): 58 (1860)
Aspidosperma sellowii var. collinum Hassl. Repert. Spec. Nov. Regni Veg. 12: 263 (1913)
Aspidosperma sellowii var. genuinum Hassl. Repert. Spec. Nov. Regni Veg. 12: 263 (1913)

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Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000291329
Tropicos 1800140
KEW urn:lsid:ipni.org:names:22020-2
The Plant List kew-17330
Open Tree Of Life 5784596
NCBI Taxonomy 2072222
IPNI 22020-2
GBIF 7316913
Freebase /m/011srnpl
Wikipedia Aspidosperma_olivaceum
CMAUP NPO18827

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Lysosomal Exocytosis of Olivacine on the Way to Explain Drug Resistance in Cancer Cells Wiatrak B, Gębarowski T, Czwojdziński E, Gąsiorowski K, Tylińska B Int J Mol Sci 30-May-2022
PMCID:PMC9181543
doi:10.3390/ijms23116119
PMID:35682799
Studies on Activities and Chemical Characterization of Medicinal Plants in Search for New Antimalarials: A Ten Year Review on Ethnopharmacology Ceravolo IP, Aguiar AC, Adebayo JO, Krettli AU Front Pharmacol 22-Sep-2021
PMCID:PMC8493299
doi:10.3389/fphar.2021.734263
PMID:34630109
Evaluation of Interactions of Selected Olivacine Derivatives with DNA and Topoisomerase II Tylińska B, Dobosz A, Spychała J, Cwynar-Zając Ł, Czyżnikowska Ż, Kuźniarski A, Gębarowski T Int J Mol Sci 06-Aug-2021
PMCID:PMC8395211
doi:10.3390/ijms22168492
PMID:34445198
Bioactive Olivacine Derivatives—Potential Application in Cancer Therapy Tylińska B, Wiatrak B Biology (Basel) 21-Jun-2021
PMCID:PMC8235335
doi:10.3390/biology10060564
PMID:34205757
Plant-Based Indole Alkaloids: A Comprehensive Overview from a Pharmacological Perspective Omar F, Tareq AM, Alqahtani AM, Dhama K, Sayeed MA, Emran TB, Simal-Gandara J Molecules 15-Apr-2021
PMCID:PMC8071433
doi:10.3390/molecules26082297
PMID:33921093
Amino acid–derived defense metabolites from plants: A potential source to facilitate novel antimicrobial development Parthasarathy A, Borrego EJ, Savka MA, Dobson RC, Hudson AO J Biol Chem 19-Feb-2021
PMCID:PMC8024917
doi:10.1016/j.jbc.2021.100438
PMID:33610552
Role of Melatonin in the Synchronization of Asexual Forms in the Parasite Plasmodium falciparum Singh MK, Dias BK, Garcia CR Biomolecules 27-Aug-2020
PMCID:PMC7563138
doi:10.3390/biom10091243
PMID:32867164
Antitumor Activity of New Olivacine Derivatives Piasny J, Wiatrak B, Dobosz A, Tylińska B, Gębarowski T Molecules 28-May-2020
PMCID:PMC7321363
doi:10.3390/molecules25112512
PMID:32481577
Antiplasmodial natural products: an update Tajuddeen N, Van Heerden FR Malar J 05-Dec-2019
PMCID:PMC6896759
doi:10.1186/s12936-019-3026-1
PMID:31805944
Aspidosperma pyrifolium, a medicinal plant from the Brazilian caatinga, displays a high antiplasmodial activity and low cytotoxicity Ceravolo IP, Zani CL, Figueiredo FJ, Kohlhoff M, Santana AE, Krettli AU Malar J 26-Nov-2018
PMCID:PMC6257952
doi:10.1186/s12936-018-2568-y
PMID:30477525
Aspidosperma species as sources of anti-malarials: uleine is the major anti-malarial indole alkaloid from Aspidosperma parvifolium (Apocynaceae) Dolabela MF, Póvoa MM, Brandão GC, Rocha FD, Soares LF, de Paula RC, de Oliveira AB Malar J 10-Dec-2015
PMCID:PMC4676157
doi:10.1186/s12936-015-0997-4
PMID:26655827
Anti-malarial activity of indole alkaloids isolated from Aspidosperma olivaceum Chierrito TP, Aguiar AC, de Andrade IM, Ceravolo IP, Gonçalves RA, de Oliveira AJ, Krettli AU Malar J 14-Apr-2014
PMCID:PMC4006081
doi:10.1186/1475-2875-13-142
PMID:24731256
Enantiomeric Natural Products: Occurrence and Biogenesis Finefield JM, Sherman DH, Kreitman M, Williams RM Angew Chem Int Ed Engl 03-May-2012
PMCID:PMC3498912
doi:10.1002/anie.201107204
PMID:22555867

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / Hydroxybenzoic acid derivatives / Gallic acid and derivatives / Gallic acids
Gallic Acid 370 Click to see C1=C(C=C(C(=C1O)O)O)C(=O)O 170.12 unknown via CMAUP database
> Lignans, neolignans and related compounds / Furanoid lignans / Tetrahydrofuran lignans / 7,9-epoxylignans
5-(4-Hydroxy-3-methoxyphenyl)-3-[(4-hydroxy-3-methoxyphenyl)methyl]-4-(hydroxymethyl)oxolan-3-ol 586733 Click to see COC1=C(C=CC(=C1)CC2(COC(C2CO)C3=CC(=C(C=C3)O)OC)O)O 376.40 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / Phenolic glycosides
3-Methoxy-4-hydroxyphenyl 6-O-(3,4,5-trihydroxybenzoyl)-beta-D-glucopyranoside 102442448 Click to see COC1=C(C=CC(=C1)OC2C(C(C(C(O2)COC(=O)C3=CC(=C(C(=C3)O)O)O)O)O)O)O 454.40 unknown via CMAUP database
4-Hydroxy-3,5-dimethoxyphenyl 6-O-galloyl-beta-D-glucopyranoside 100916644 Click to see COC1=CC(=CC(=C1O)OC)OC2C(C(C(C(O2)COC(=O)C3=CC(=C(C(=C3)O)O)O)O)O)O 484.40 unknown via CMAUP database
> Organoheterocyclic compounds / Indoles and derivatives / Carbazoles
1,5-dimethyl-6H-pyrido[4,3-b]carbazole 5281407 Click to see CC1=C2C=CN=C(C2=CC3=C1NC4=CC=CC=C43)C 246.31 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavans / Catechins
Cianidanol 9064 Click to see C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O 290.27 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavans / Catechins / Epigallocatechins
Gallocatechin 65084 Click to see C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O 306.27 unknown via CMAUP database
> Phenylpropanoids and polyketides / Tannins
beta-Glucogallin 124021 Click to see C1=C(C=C(C(=C1O)O)O)C(=O)OC2C(C(C(C(O2)CO)O)O)O 332.26 unknown via CMAUP database
Pentagalloylglucose 65238 Click to see C1=C(C=C(C(=C1O)O)O)C(=O)OCC2C(C(C(C(O2)OC(=O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O)OC(=O)C5=CC(=C(C(=C5)O)O)O)OC(=O)C6=CC(=C(C(=C6)O)O)O 940.70 unknown via CMAUP database
> Phenylpropanoids and polyketides / Tannins / Complex tannins
(1R,2R,20R,42S,46S)-46-[(2R,3S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-6-yl]-7,8,9,12,13,14,25,26,27,30,31,32,35,36,37-pentadecahydroxy-3,18,21,41,43-pentaoxanonacyclo[27.13.3.138,42.02,20.05,10.011,16.023,28.033,45.034,39]hexatetraconta-5,7,9,11,13,15,23,25,27,29(45),30,32,34(39),35,37-pentadecaene-4,17,22,40,44-pentone 16167199 Click to see C1C(C(OC2=C1C(=C(C(=C2)O)C3C4C5C6C(COC(=O)C7=CC(=C(C(=C7C8=C(C(=C(C=C8C(=O)O6)O)O)O)O)O)O)OC(=O)C9=CC(=C(C(=C9C1=C(C(=C(C(=C1O)O)O)C1=C(C3=C(C(=C1O)O)O)C(=O)O4)C(=O)O5)O)O)O)O)C1=CC(=C(C=C1)O)O)O 1206.90 unknown via CMAUP database
Acutissimin A 16132408 Click to see C1C(C(OC2=C1C(=CC(=C2C3C4C5C6C(COC(=O)C7=CC(=C(C(=C7C8=C(C(=C(C=C8C(=O)O6)O)O)O)O)O)O)OC(=O)C9=CC(=C(C(=C9C1=C(C(=C(C(=C1O)O)O)C1=C(C3=C(C(=C1O)O)O)C(=O)O4)C(=O)O5)O)O)O)O)O)C1=CC(=C(C=C1)O)O)O 1206.90 unknown via CMAUP database
> Phenylpropanoids and polyketides / Tannins / Hydrolyzable tannins
3-(beta-D-Glucopyranosyloxy)-4,5-dihydroxybenzoic acid 101683334 Click to see C1=C(C=C(C(=C1O)O)OC2C(C(C(C(O2)CO)O)O)O)C(=O)O 332.26 unknown via CMAUP database

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