Quillaja saponaria

Details Top

Internal ID UUID64402223e1270246275876
Scientific name Quillaja saponaria
Authority Molina
First published in Sag. Stor. Nat. Chili : 355 (1782)

Ethnobotanical Use Top

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General Uses Top

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Common products:
Quillaja saponaria (soapbark) is the source of commercial quillaja saponin extracts, standardized for foaming and surfactant applications in food, beverages, and consumer products. Tinctures and flavoring preparations, as well as powdered extracts, are traded for use as foaming agents and flavor components.

Industrial and craft applications:
The extracts are used as high-foaming surfactants and wetting agents in fire-fighting foams for hydrocarbon and solvent fires, and as emulsifiers and stabilizers in agricultural pesticide formulations and adjuvants for agrochemical spray solutions. They also serve as detergents or co-surfactants in industrial and institutional cleaning products, as dispersants in microencapsulation and nanomaterials, and as assay reagents (e.g., hemolytic activity, protein precipitation) in laboratory protocols.

Food and beverages (non-medicinal):
Quillaja extracts are employed as natural foaming agents in beverages such as root beers and alcoholic malt beverages to produce stable foams, and as flavoring ingredients in confectionery and baked goods where a mild characteristic taste is desired.

Colorants and tanning:
The bark is rich in condensed tannins and yields brown colorants used historically for dyeing protein fibers. The same tannin-rich material is used in vegetable leather tanning to produce firm, brown-colored leathers.

Wood and fiber:
Dense, durable wood is used locally for fuel, charcoal, and general construction; small-dimension uses are also reported in Chile.

Fragrance and cosmetics:
Quillaja extracts are used in shampoos, body washes, and other rinse-off cosmetics as foaming and cleansing agents; they also function as natural surfactant systems in skin-care and hair-care preparations.

Properties relevant to use:
Commercial extracts deliver defined saponin profiles that confer strong surface activity, rapid foam generation, and stable emulsions suitable for food and agrochemical systems. Bark tannin composition supports durable vegetable tanning and provides brown hues on protein fibers. The heartwood is hard and dense, conferring durability in fuel and structural uses.

Standards and regulation:
Saponin-containing extracts are regulated as natural flavoring agents in many jurisdictions when used in foods and beverages; corresponding regulations govern labeling and maximum use levels. Specified mixtures of quillaja saponins are recognized as vaccine adjuvants in regulatory frameworks for human vaccines, and foams employing quillaja surfactants must comply with relevant fire-fighting foam specifications.

Sustainability and sourcing:
Commercial material is primarily wild-harvested in Chile, with national regulations controlling extraction volumes to address concerns about overharvesting and habitat impacts. Industry activities include management plans, planting programs, and product traceability measures to support long-term supply.

Synonyms Top

Scientific name Authority First published in
Quillaja poeppigii Walp. Repert. Bot. Syst. 2: 52 (1843)
Quillaja saponaria Poir. Encycl. [J. Lamarck & al.] 6(1): 33. 1804 [2 Oct 1804]
Smegmadermos emarginata Ruiz & Pav. Syst. Veg. Fl. Peruv. Chil. 1: 288. 1798 [late Dec 1798]
Leucoxyla saponaria Rojas Acosta Cat. Hist. Nat. Corrientes 69 (1897).
Quillaja molinae Ser. Prodr. [A. P. de Candolle] 2: 547. 1825 [mid Nov 1825]
Quillaja smegmadermis St.-Lag. Ann. Soc. Bot. Lyon vii. (1880) 133.
Quillaja smegmadermos Ser. Prodr. [A. P. de Candolle] 2: 547. 1825 [mid Nov 1825]
Smegmaria emarginata Willd. Sp. Pl., ed. 4 [Willdenow] 4(2): 1123. 1806 [Apr 1806]

Common names Top

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Language Common/alternative name
English soapbark
Spanish quillaja smegmadermos
Spanish quillaja poeppigii
Spanish quillaja molinae
Spanish quillay
Arabic القلاجة الصابونية
Arabic كلاجة صابونية
Arabic قلاجة صابونية
Belarusian Мыльнае дрэва
Bulgarian сапунена кора
Czech mydlokor tupolistý
Esperanto kilajoarbo
Estonian tšiili seebikoorepuu
Persian کویلاجا ساپناریا
Finnish suopapuu
French bois de panama
io quilayo
Icelandic sáputré
Japanese 石鹸木
Japanese シャボンの木
Japanese シャボンノキ
Japanese キラヤ
Japanese サボンの木
Japanese キラジャ
Norwegian Bokmål såpetre
Polish mydłodrzew właściwy
Portuguese quilaia
Russian Квиллайя настоящая
Russian Квилаха мыльная
Russian Квиллайя мыльная
Russian Квилаха настоящая
Swedish såpträd

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Southern America
    • Southern South America
      • Chile Central
    • Western South America
      • Bolivia

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000734711
UNII HIU9R169Y7
USDA Plants QUSA4
Tropicos 27802509
KEW urn:lsid:ipni.org:names:731377-1
The Plant List kew-2870262
PFAF Quillaja saponaria
Open Tree Of Life 156933
Observations.org 187696
NCBI Taxonomy 32244
IUCN Red List 131407078
IPNI 731377-1
iNaturalist 181934
GBIF 3029379
Freebase /m/04grdf
EPPO QILSA
EOL 241669
Calflora (Californian flora) 13010
USDA GRIN 30776
Wikipedia Quillaja_saponaria

Genomes (via NCBI) Top

Below is displayed the reference genome only!
If you wish to browse all genomes for this plant click here.
Accession Assembly
Name Level Submitter Released Coverage Size
GCA_029379385.1 Quisap_AO_1.2 Chromosome John Innes Centre 2023-03-24 74.94 338.45 Mb

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
The protective role of prebiotics and probiotics on diarrhea and gut damage in the rotavirus-infected piglets Yang H, Fan X, Mao X, Yu B, He J, Yan H, Wang J J Anim Sci Biotechnol 03-May-2024
PMCID:PMC11067158
doi:10.1186/s40104-024-01018-3
PMID:38698473
Campylobacter jejuni virulence factors: update on emerging issues and trends Tikhomirova A, McNabb ER, Petterlin L, Bellamy GL, Lin KH, Santoso CA, Daye ES, Alhaddad FM, Lee KP, Roujeinikova A J Biomed Sci 01-May-2024
PMCID:PMC11064354
doi:10.1186/s12929-024-01033-6
PMID:38693534
Lot-to-lot immunogenicity consistency of the respiratory syncytial virus prefusion F protein vaccine in older adults Ferguson M, Murray A, Pliamm L, Rombo L, Sanmartin Berglund J, David MP, De Schrevel N, Maschino F, Kotb S, Olivier A, Hulstrøm V Vaccine X 27-Apr-2024
PMCID:PMC11090873
doi:10.1016/j.jvacx.2024.100494
PMID:38746060
Differential Utility Losses in Herpes Zoster Cases Between Vaccinated and Unvaccinated Subjects: A Meta-analysis of Three Clinical Trials Giannelos N, Francq B, Curran D Clin Drug Investig 25-Apr-2024
PMCID:PMC11088541
doi:10.1007/s40261-024-01355-1
PMID:38662318
AdjuvareDB: A comprehensive database for candidate adjuvant compendium in clinic Ren D, Jin J, Xiong S, Xia D, Zhao X, Guo H, Yang X, Yu J, Liang T, Guo L Clin Transl Med 24-Apr-2024
PMCID:PMC11043087
doi:10.1002/ctm2.1669
PMID:38659057
Lung mucosal immunity to NTHi vaccine antigens: Antibodies in sputum of chronic obstructive pulmonary disease patients Baffetta F, Buonsanti C, Moraschini L, Aprea S, Canè M, Lombardi S, Contorni M, Rondini S, Arora AK, Bardelli M, Finco O, Serruto D, Paccani SR Hum Vaccin Immunother 24-Apr-2024
PMCID:PMC11057560
doi:10.1080/21645515.2024.2343544
PMID:38655676
Saponin Extracts Utilization as Dietary Additive in Ruminant Nutrition: A Meta-Analysis of In Vivo Studies Yanza YR, Irawan A, Jayanegara A, Ramadhani F, Respati AN, Fitri A, Hidayat C, Niderkorn V, Cieslak A, Szumacher-Strabel M, Hidayat R, Tanuwiria UH Animals (Basel) 19-Apr-2024
PMCID:PMC11047613
doi:10.3390/ani14081231
PMID:38672383
Monophosphoryl Lipid A–based Adjuvant to Promote the Immunogenicity of Multivalent Meningococcal Polysaccharide Conjugate Vaccines Alugupalli KR Immunohorizons 16-Apr-2024
PMCID:PMC11066721
doi:10.4049/immunohorizons.2400013
PMID:38625118
Synthesis of Quillaic Acid through Sustainable C–H Bond Activations Wang YC, Chen CR, Chen CY, Liang PH J Org Chem 10-Apr-2024
PMCID:PMC11040720
doi:10.1021/acs.joc.3c02958
PMID:38595071
Quillaja saponin mitigates methotrexate-provoked renal injury; insight into Nrf-2/Keap-1 pathway modulation with suppression of oxidative stress and inflammation Abdel-Reheim MA, Ali ME, Gaafar AG, Ashour AA J Pharm Health Care Sci 09-Apr-2024
PMCID:PMC11003044
doi:10.1186/s40780-024-00330-4
PMID:38594773
Impact of Heavy Metal Pollution in the Environment on the Metabolic Profile of Medicinal Plants and Their Therapeutic Potential Asiminicesei DM, Fertu DI, Gavrilescu M Plants (Basel) 21-Mar-2024
PMCID:PMC10976221
doi:10.3390/plants13060913
PMID:38592933
Immune response to the recombinant herpes zoster vaccine in people living with HIV over 50 years of age compared to non-HIV age-/gender-matched controls (SHINGR’HIV): a multicenter, international, non-randomized clinical trial study protocol Hentzien M, Bonnet F, Bernasconi E, Biver E, Braun DL, Munting A, Leuzinger K, Leleux O, Musardo S, Prendki V, Schmid P, Staehelin C, Stoeckle M, Walti CS, Wittkop L, Appay V, Didierlaurent AM, Calmy A BMC Infect Dis 19-Mar-2024
PMCID:PMC10949601
doi:10.1186/s12879-024-09192-5
PMID:38504173
GD2-targeting therapy: a comparative analysis of approaches and promising directions Philippova J, Shevchenko J, Sennikov S Front Immunol 15-Mar-2024
PMCID:PMC10979305
doi:10.3389/fimmu.2024.1371345
PMID:38558810
Terpenes and Terpenoids Conjugated with BODIPYs: An Overview of Biological and Chemical Properties Stanková J, Jurášek M, Hajdúch M, Džubák P J Nat Prod 14-Mar-2024
PMCID:PMC11061839
doi:10.1021/acs.jnatprod.3c00961
PMID:38482846
Extracted Eucalyptus globulus Bark Fiber as a Potential Substrate for Pinus radiata and Quillaja saponaria Germination Ferrer-Villasmil V, Fuentealba C, Reyes-Contreras P, Rubilar R, Cabrera-Barjas G, Bravo-Arrepol G, Escobar-Avello D Plants (Basel) 11-Mar-2024
PMCID:PMC10975318
doi:10.3390/plants13060789
PMID:38592776

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lignans, neolignans and related compounds / Lignan glycosides
(+)-Lyoniresinol 3alpha-O-beta-D-glucopyranoside 10483388 Click to see 582.60 unknown https://doi.org/10.1016/0031-9422(95)00496-T
2-((7-Hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)-3-(hydroxymethyl)-6,8-dimethoxy-1,2,3,4-tetrahydronaphthalen-2-yl)methoxy)-6-(hydroxymethyl)oxane-3,4,5-triol 14521083 Click to see 582.60 unknown https://doi.org/10.1016/0031-9422(95)00496-T
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Branched fatty acids / Methyl-branched fatty acids
2-Methylbutanoic Acid 8314 Click to see 102.13 unknown https://doi.org/10.1016/S0008-6215(00)00248-2
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
9-Formyl-5,10-dihydroxy-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid 4483642 Click to see 486.70 unknown https://doi.org/10.1111/J.2042-7158.2011.01263.X
https://doi.org/10.1016/J.JEP.2010.09.016
Gypsogenin 92825 Click to see 470.70 unknown https://doi.org/10.1016/S0031-9422(97)00716-4
Quillaic Acid 101810 Click to see 486.70 unknown https://doi.org/10.1016/S0031-9422(97)00716-4
https://doi.org/10.1111/J.2042-7158.2011.01263.X
https://doi.org/10.1016/J.JEP.2010.09.016
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Glycosyl compounds / Phenolic glycosides
2-(Hydroxymethyl)-6-(3,4,5-trimethoxyphenoxy)oxane-3,4,5-triol 13922637 Click to see 346.33 unknown https://doi.org/10.1016/0031-9422(95)00496-T
3,4,5-Trimethoxyphenyl beta-D-glucopyranoside 636454 Click to see 346.33 unknown https://doi.org/10.1016/0031-9422(95)00496-T
7-[(6-O-I+/--L-Arabinopyranosyl-I(2)-D-glucopyranosyl)oxy]-4-methyl-1(3H)-isobenzofuranone 162979832 Click to see 458.40 unknown https://doi.org/10.1016/0031-9422(95)00496-T
7-Hydroxy-4-methylphthalide O-[arabinosyl-(1->6)-glucoside] 22297293 Click to see CC1=C2COC(=O)C2=C(C=C1)OC3C(C(C(C(O3)COC4C(C(C(CO4)O)O)O)O)O)O 458.40 unknown https://doi.org/10.1016/0031-9422(95)00496-T

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