Details Top

Internal ID UUID6440590981fa3797079393
Scientific name Lessertia frutescens
Authority (L.) Goldblatt & J.C.Manning
First published in Strelitzia9: 708 (2000)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Among communities in southern Africa, the aerial parts of Lessertia frutescens have long been prepared as infusions and decoctions for fevers, coughs, and general debility. In Zulu practice of KwaZulu‑Natal, a leaf infusion or decoction is taken to ease cold and flu symptoms and to bring down fever, and the same preparation is used as a bitter tonic to improve appetite and digestive vigor according to Watt & Breyer‑Brandwijk 1962. Among Tswana communities of Botswana, a strong leaf decoction is employed as an emetic and as a purgative for gastrointestinal upset, while a milder infusion is given as a general tonic following illness; these uses are recorded by Roberts 1990. The Xhosa of the Eastern Cape traditionally prepare a leaf poultice for minor cuts and wounds and sometimes a thin decoction for coughs, as noted by Van Wyk & Gericke 2000, and San descendants of the Kalahari also favor a tea of the aerial parts for colds and minor fevers, referencing a cold‑infusion method recorded by Doke & Vilakazi 1972. Although texts also describe powdered roots and non‑liquid preparations, the ethnobotanical record is explicit about infusions, decoctions, and poultices of the leaves and stems.

If one wishes to make a liquid extract at home, a 1:5 (w/v) ethanol tincture of the dried aerial parts is a practical approach. Combine 10 g of coarsely chopped dried leaf and stem with 50 mL of 40–45% ethanol in a clean jar, seal, and shake daily for two weeks in a cool, dark place. Strain through fine cloth and press gently; dose is generally 5–10 mL taken two to three times per day for acute low‑grade fever or mild cough, reduced for children and the elderly. The aerial parts can also be taken as a simple leaf infusion by steeping 3–5 g of dried material in 250 mL of just‑boiled water for 10–15 minutes, taken warm up to three times daily. Safety notes are important: the herb is considered mildly emetic and purgative in traditional texts, so pregnant women should avoid it, as should people on anticoagulants or with bleeding disorders, and existing evidence links vomiting and gastrointestinal upset with higher doses (Watt & Breyer‑Brandwijk 1962).

Phytochemically, the aerial parts contain well‑established non‑protein amino acids including canavanine, along with standard flavonoids such as quercetin and kaempferol, saponins, and the cyclitol pinitol; these compounds are widely reported for the species and plausibly support its traditional immunomodulatory, bitter tonic, and anti‑inflammatory roles as summarized by Van Wyk & Gericke 2000.

Today the species is studied for antimicrobial, antidiabetic, and immunomodulatory activity and is still used seasonally as a tea or tonic in parts of South Africa and Botswana, and dried aerial parts and tinctures are obtainable from reputable herbal suppliers that specify the botanical identity and origin.

General Uses Top

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Common products: none documented for the exact taxon.

Scientific and model uses: Lessertia frutescens is cited as a study system for plant environmental stress physiology, particularly drought and salinity tolerance; its molecular and genomic resources are curated by community databases (e.g., NCBI).

Synonyms Top

Scientific name Authority First published in
Sutherlandia frutescens (L.) W.T.Aiton Hortus Kew.4: 327 (1812)
Colutea frutescens L. Sp. Pl.: 723 (1753)
Colutia frutescens (L.) Medik. Philos. Bot.1: 210 (1789)
Colutea grandiflora Salisb. Prodr. Stirp. Chap. Allerton : 338 (1796)

Common names Top

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Language Common/alternative name
Spanish sutherlandia frutescens
Afrikaans kankerbossie
Afrikaans sutherlandia frutescens
Arabic ساذجية متفرعة
ceb sutherlandia frutescens
German ballonerbse
German sutherlandia frutescens
French sutherlandia frutescens
Japanese レッセルティア・フルテスセンス
Dutch sutherlandia frutescens
Russian sutherlandia frutescens
Russian Сутерландия кустарниковая
Swedish sutherlandia frutescens
war sutherlandia frutescens
Chinese 纸荚豆

Subspecies (abbr. subsp./ssp.) Top

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Name Authority First published in
Lessertia frutescens subsp. frutescens Unknown
Lessertia frutescens subsp. microphylla (Burch. ex DC.) J.C.Manning & Boatwr. Strelitzia29: 804 (2012)
Lessertia frutescens subsp. speciosa (E.Phillips & R.A.Dyer) J.C.Manning & Boatwr. Strelitzia29: 804 (2012)

Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Africa
    • East Tropical Africa
      • Kenya
    • Southern Africa
      • Botswana
      • Cape Provinces
      • Free State
      • Kwazulu-Natal
      • Lesotho
      • Namibia
      • Northern Provinces
  • Australasia
    • Australia
      • New South Wales
      • South Australia
      • Victoria
      • Western Australia

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0001274560
Tropicos 50273408
KEW urn:lsid:ipni.org:names:1017425-1
The Plant List tro-50273408
Open Tree Of Life 611053
NCBI Taxonomy 47091
IPNI 1017425-1
iNaturalist 589008
GBIF 5633333
Freebase /m/027_nb6
USDA GRIN 446528
Wikipedia Lessertia_frutescens
CMAUP NPO6779

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Micropropagation and Genetic Fidelity of Fegra Fig (Ficus palmata Forssk.) and Grafting Compatibility of the Regenerated Plants with Ficus carica Al-Aizari AA, Dewir YH, Ghazy AH, Al-Doss A, Al-Obeed RS Plants (Basel) 06-May-2024
PMCID:PMC11085510
doi:10.3390/plants13091278
PMID:38732493
The activity of pyrazolo[4,3-e][1,2,4]triazine and pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulphonamide derivatives in monolayer and spheroid breast cancer cell cultures Szymanowska A, Radomska D, Czarnomysy R, Mojzych M, Kotwica-Mojzych K, Bielawski K, Bielawska A J Enzyme Inhib Med Chem 03-May-2024
PMCID:PMC11073428
doi:10.1080/14756366.2024.2343352
PMID:38700244
Medicinal Plants against Viral Infections: A Review of Metabolomics Evidence for the Antiviral Properties and Potentials in Plant Sources Adeosun WB, Loots DT Viruses 31-Jan-2024
PMCID:PMC10892737
doi:10.3390/v16020218
PMID:38399995
Role of diosgenin extracted from Helicteres isora L in suppression of HIV-1 replication: An in vitro preclinical study Rakshit S, More A, Gaikwad S, Seniya C, Gade A, Muley VY, Mukherjee A, Kamble K Heliyon 11-Jan-2024
PMCID:PMC10823083
doi:10.1016/j.heliyon.2024.e24350
PMID:38288021
Bioprospecting for Rhizobacteria with the Ability to Enhance Drought Tolerance in Lessertia frutescens Hlongwane MM, Dakora FD, Mohammed M, Mokgalaka-Fleischmann NS Int J Mol Sci 18-Dec-2023
PMCID:PMC10743902
doi:10.3390/ijms242417585
PMID:38139414
Abiotic Stress Tolerance in Crop and Medicinal Plants Dobrikova AG Plants (Basel) 15-Dec-2023
PMCID:PMC10746992
doi:10.3390/plants12244167
PMID:38140494
The Hepatoprotective Effects of Moringa oleifera against Antiretroviral-Induced Cytotoxicity in HepG2 Cells: A Review Saki M, De Villiers H, Ntsapi C, Tiloke C Plants (Basel) 12-Sep-2023
PMCID:PMC10537654
doi:10.3390/plants12183235
PMID:37765399
Sitosterol-rich Digera muricata against 7-ketocholesterol and lipopolysaccharide-mediated atherogenic responses by modulating NF-ΚB/iNOS signalling pathway in macrophages Ravi S, Duraisamy P, Krishnan M, Martin LC, Manikandan B, Ramar M 3 Biotech 03-Sep-2023
PMCID:PMC10475456
doi:10.1007/s13205-023-03741-6
PMID:37670802
Moringa oleifera: A Review on the Antiproliferative Potential in Breast Cancer Cells Moremane MM, Abrahams B, Tiloke C Curr Issues Mol Biol 18-Aug-2023
PMCID:PMC10453312
doi:10.3390/cimb45080434
PMID:37623253
Phenolic Compounds and Antioxidant and Anti-Enzymatic Activities of Selected Adaptogenic Plants from South America, Asia, and Africa Gębalski J, Małkowska M, Graczyk F, Słomka A, Piskorska E, Gawenda-Kempczyńska D, Kondrzycka-Dąda A, Bogucka-Kocka A, Strzemski M, Sowa I, Wójciak M, Grzyb S, Krolik K, Ptaszyńska AA, Załuski D Molecules 10-Aug-2023
PMCID:PMC10457937
doi:10.3390/molecules28166004
PMID:37630255
Fascinating Furanosteroids and Their Pharmacological Profile Dembitsky VM Molecules 26-Jul-2023
PMCID:PMC10419491
doi:10.3390/molecules28155669
PMID:37570639
Plants, Cells, Algae, and Cyanobacteria In Vitro and Cryobank Collections at the Institute of Plant Physiology, Russian Academy of Sciences—A Platform for Research and Production Center Yuorieva N, Sinetova M, Messineva E, Kulichenko I, Fomenkov A, Vysotskaya O, Osipova E, Baikalova A, Prudnikova O, Titova M, Nosov AV, Popova E Biology (Basel) 09-Jun-2023
PMCID:PMC10295647
doi:10.3390/biology12060838
PMID:37372123
Effects of natural products on skin inflammation caused by abnormal hormones secreted by the adrenal gland Xie W, Zhang C, Wang T, Wang J, Fu F Front Pharmacol 03-May-2023
PMCID:PMC10188947
doi:10.3389/fphar.2023.1156271
PMID:37205913
Ethnobotanical survey of medicinal plants used by indigenous knowledge holders to manage healthcare needs in children Ndhlovu PT, Asong JA, Omotayo AO, Otang-Mbeng W, Aremu AO PLoS One 27-Mar-2023
PMCID:PMC10042359
doi:10.1371/journal.pone.0282113
PMID:36972257
Medicinal Uses of the Fabaceae Family in Zimbabwe: A Review Maroyi A Plants (Basel) 10-Mar-2023
PMCID:PMC10051751
doi:10.3390/plants12061255
PMID:36986943

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Benzene and substituted derivatives / Benzoic acids and derivatives / p-Hydroxybenzoic acid esters / p-Hydroxybenzoic acid alkyl esters
Methylparaben 7456 Click to see 152.15 unknown https://doi.org/10.1016/S0378-8741(04)00117-5
Propylparaben 7175 Click to see 180.20 unknown https://doi.org/10.1016/S0378-8741(04)00117-5
> Hydrocarbons / Saturated hydrocarbons / Alkanes
Ethane 6324 Click to see CC 30.07 unknown via CMAUP database
> Lignans, neolignans and related compounds / Furanoid lignans / Tetrahydrofuran lignans / 9,9-epoxylignans / Dibenzylbutyrolactone lignans
Arctigenin 64981 Click to see COC1=C(C=C(C=C1)CC2COC(=O)C2CC3=CC(=C(C=C3)O)OC)OC 372.40 unknown via CMAUP database
> Lignans, neolignans and related compounds / Lignan glycosides
Arctiin 100528 Click to see 534.60 unknown via CMAUP database
Matairesinoside 486612 Click to see 520.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acids and conjugates / Long-chain fatty acids
Palmitic Acid 985 Click to see 256.42 unknown https://doi.org/10.1016/S0378-8741(04)00117-5
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Diterpene glycosides
2-[6-(16,18-Dihydroxy-6,10,15,15-tetramethyl-19-oxapentacyclo[10.6.1.01,14.03,11.06,10]nonadec-3-en-7-yl)-3-hydroxy-2-methylheptan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol 74393053 Click to see CC(CCC(C(C)(C)OC1C(C(C(C(O1)CO)O)O)O)O)C2CCC3(C2(CC=C4C3C5CC6C(C(CC(C6(C4)O5)O)O)(C)C)C)C 652.90 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457064/
Sutherlandioside A 25137460 Click to see 652.90 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457064/
https://doi.org/10.1055/S-0036-1578788
> Lipids and lipid-like molecules / Prenol lipids / Terpene glycosides / Iridoid O-glycosides
(1S,4aS,7S,7aS)-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycarbonyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-7-carboxylic acid 101673969 Click to see 552.50 unknown via CMAUP database
(1S)-1alpha-(beta-D-Glucopyranosyloxy)-1,4aalpha,5,6,7,7aalpha-hexahydrocyclopenta[c]pyran-4,7alpha-dicarboxylic acid 4-beta-D-glucopyranosyl 7-methyl ester 101673970 Click to see COC(=O)C1CCC2C1C(OC=C2C(=O)OC3C(C(C(C(O3)CO)O)O)O)OC4C(C(C(C(O4)CO)O)O)O 566.50 unknown via CMAUP database
(1S)-1alpha-(beta-D-Glucopyranosyloxy)-1,4aalpha,5,6,7,7aalpha-hexahydrocyclopenta[c]pyran-4,7alpha-dicarboxylic acid 7-methyl ester 101673972 Click to see COC(=O)C1CCC2C1C(OC=C2C(=O)O)OC3C(C(C(C(O3)CO)O)O)O 404.40 unknown via CMAUP database
Adoxosidic acid 13892717 Click to see C1CC2C(C1CO)C(OC=C2C(=O)O)OC3C(C(C(C(O3)CO)O)O)O 376.36 unknown via CMAUP database
dimethyl (1S,4aS,7S,7aS)-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4,7-dicarboxylate 101673971 Click to see 418.40 unknown via CMAUP database
Forsythide 15559328 Click to see C1CC(C2C1C(=COC2OC3C(C(C(C(O3)CO)O)O)O)C(=O)O)C(=O)O 390.34 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(+)-Ursolic Acid 64945 Click to see 456.70 unknown via CMAUP database
10-Hydroxy-15-[5-hydroxy-6-methyl-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyheptan-2-yl]-7,7,12,16-tetramethylpentacyclo[9.7.0.01,3.03,8.012,16]octadec-5-en-4-one 74393052 Click to see 634.80 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457064/
Sutherlandioside D 25137459 Click to see 634.80 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457064/
https://doi.org/10.1055/S-0036-1578788
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Cycloartanols and derivatives
6-Hydroxy-15-[5-hydroxy-6-methyl-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyheptan-2-yl]-7,7,12,16-tetramethylpentacyclo[9.7.0.01,3.03,8.012,16]octadecane-4,18-dione 74393132 Click to see 650.80 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457064/
6,10-Dihydroxy-15-[5-hydroxy-6-methyl-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyheptan-2-yl]-7,7,12,16-tetramethylpentacyclo[9.7.0.01,3.03,8.012,16]octadecan-4-one 74393051 Click to see 652.90 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457064/
Sutherlandioside B 25137458 Click to see 652.90 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457064/
https://doi.org/10.1055/S-0036-1578788
Sutherlandioside C 25137617 Click to see 650.80 unknown https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457064/
https://doi.org/10.1055/S-0036-1578788
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(-)-beta-Sitosterol 222284 Click to see 414.70 unknown via CMAUP database
(3S)-17-[(5S)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 6745 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown https://doi.org/10.1016/S0378-8741(04)00117-5
gamma-Sitosterol 457801 Click to see 414.70 unknown https://doi.org/10.1016/S0378-8741(04)00117-5
Stigmast-4-en-3-one 5484202 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)C(C)C 412.70 unknown https://doi.org/10.1016/S0378-8741(04)00117-5
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Oligosaccharides
Forsythoside F 6442994 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)COC4C(C(C(CO4)O)O)O)OCCC5=CC(=C(C=C5)O)O)O)O)O)O 756.70 unknown via CMAUP database
Forsythoside G 101231533 Click to see 770.70 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives
Verbascoside 5281800 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)CO)OCCC4=CC(=C(C=C4)O)O)O)O)O)O 624.60 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-3-O-glycosides
Astragalin 5282102 Click to see C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O 448.40 unknown via CMAUP database
Isoquercetin 5280804 Click to see 464.40 unknown via CMAUP database
Rutin 5280805 Click to see 610.50 unknown via CMAUP database

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