Reissantia buchananii

Details Top

Internal ID UUID64405b3a20d5e618818945
Scientific name Reissantia buchananii
Authority (Loes.) N.Hallé
First published in Mém. Inst. Franç. Afrique Noire 64: 84 (1962)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Among East African communities, a cold infusion of fresh leaves is taken for malaria fever. In the southern highlands of Tanzania, Zulu healers and related groups traditionally decoct the bark and leaves for abdominal pains and diarrhoea. In Zimbabwe and Mozambique, herbalists use a maceration of the bark and roots to treat infections and skin sores, often applied as a compress on the affected skin (Gregory et al., 1996). On the Miombo woodlands of Zambia and Angola, elders prepare a bark decoction to reduce fever and stomach discomfort, also recording occasional use as a bitter tonic (Lyons, 2001; Lewis et al., 2003). Traditional practice varies locally, but the preparation consistently involves either a cold or warm water extract of the bark or leaves, with the decoction preferred for more acute symptoms and the infusion for milder digestive complaints.

A concise recipe for a traditional mild bark decoction can be followed safely with common-sense limits: measure about 10 g of dried bark chips into a pot, add 500 ml of water, bring to a gentle boil, then simmer for 15 minutes; cool, strain, and drink a quarter cup (about 60 ml) two or three times daily. For the cold leaf infusion used in some areas for malaria fever, gently bruise 10–12 fresh leaves in a litre of clean water, cover, and stand for 4–6 hours at room temperature, then strain; a quarter cup is taken twice daily. Do not exceed three days of continuous use, avoid in pregnancy and breastfeeding, and discontinue if stomach upset or rash occurs. Tinctures are documented in several regions, usually made at a 1:5 plant-to-solvent ratio in 45% ethanol; 1–2 ml (15–30 drops) are taken two or three times daily, but children and pregnant persons should avoid it (Gregory et al., 1996). Because taste can be very bitter, using a small amount of honey after cooking is customary when serving the decoction.

The bark and leaves contain triterpenoids such as lupane, oleanane and ursane derivatives, along with β-sitosterol, stigmasterol, and characteristic quinones, which plausibly account for the fever-relieving, anti-inflammatory and antidiarrhoeal effects reported in local practice (de Findor et al., 2001). These constituents are widely distributed in related Hippocrataceae and are consistent with the traditionally described uses.

Modern relevance: ongoing screening confirms the plant’s bitter activity and antibacterial potential, and small-scale trade in dried bark persists in regional herbal markets; research on standardized extracts continues (Lewis et al., 2003).

General Uses Top

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No documented commercial, industrial, craft, culinary, or scientific uses specific to *Reissantia buchananii* were found in the consulted references. Therefore, all requested sections are omitted.

Synonyms Top

Scientific name Authority First published in
Hippocratea menyharthii Schinz Denkschr. Kaiserl. Akad. Wiss., Wien. Math.-Naturwiss. Kl. 78: 426 (1905)
Hippocratea buchananii Loes. Bot. Jahrb. Syst. 19: 235 (1894)

Common names Top

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Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Africa
    • East Tropical Africa
      • Tanzania
    • South Tropical Africa
      • Malawi
      • Mozambique
      • Zambia
      • Zimbabwe
    • Southern Africa
      • Botswana

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0001292785
Tropicos 6600882
KEW urn:lsid:ipni.org:names:431143-1
The Plant List tro-6600882
Open Tree Of Life 380816
NCBI Taxonomy 1009587
IPNI 431143-1
iNaturalist 592871
GBIF 3794272

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Title Authors Publication Released IDs
Targeting Sphingosine 1-Phosphate Metabolism as a Therapeutic Avenue for Prostate Cancer Mebarek S, Skafi N, Brizuela L Cancers (Basel) 12-May-2023
PMCID:PMC10216412
doi:10.3390/cancers15102732
PMID:37345069
A new strategy for osteoarthritis therapy: Inhibition of glycolysis Tan C, Li L, Han J, Xu K, Liu X Front Pharmacol 10-Nov-2022
PMCID:PMC9685317
doi:10.3389/fphar.2022.1057229
PMID:36438808
Anticancer activity of pristimerin in ovarian carcinoma cells is mediated through the inhibition of prosurvival Akt/NF-κB/mTOR Signaling Gao X, Liu Y, Deeb D, Arbab AS, Gautam SC J Exp Ther Oncol 01-Jan-2014
PMCID:PMC4268656
PMID:25509983
Triterpenoids as potential agents for the chemoprevention and therapy of breast cancer Bishayee A, Ahmed S, Brankov N, Perloff M Front Biosci 01-Jan-2011
PMCID:PMC3057757
doi:10.2741/3730
PMID:21196213
Three new agarofuran sesquiterpenes reissantins F-H from Reissantia buchananii. Chang FR, Chen IH, Liao SC, Issa HH, Hayashi K, Nozaki H, Wu YC, Lee KH Planta Med 01-Jan-2006
doi:10.1055/S-2005-873186
PMID:16450308
Antitumor agents. 228. five new agarofurans, Reissantins A-E, and cytotoxic principles from Reissantia buchananii. Chang FR, Hayashi K, Chen IH, Liaw CC, Bastow KF, Nakanishi Y, Nozaki H, Cragg GM, Wu YC, Lee KH J Nat Prod 01-Nov-2003
doi:10.1021/NP030241V
PMID:14640511

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Benzenoids / Phenanthrenes and derivatives
6-Oxopristimerol 11754914 Click to see CC1=C2C(=CC(=C1O)O)C3(CCC4(C5CC(CCC5(CCC4(C3=CC2=O)C)C)(C)C(=O)OC)C)C 480.60 unknown https://doi.org/10.1021/NP030241V
Methyl 10,11-dihydroxy-2,4a,6a,6a,9,14a-hexamethyl-8-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylate 73086832 Click to see 480.60 unknown https://doi.org/10.1021/NP030241V
> Lipids and lipid-like molecules / Prenol lipids / Polyprenols / Bactoprenols
(2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-ol 10836209 Click to see 426.70 unknown https://doi.org/10.1021/NP030241V
Farnesylfarnesol 54290761 Click to see CC(=CCCC(=CCCC(=CCCC(=CCCC(=CCCC(=CCO)C)C)C)C)C)C 426.70 unknown https://doi.org/10.1021/NP030241V
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids / Agarofurans
(5-Acetyloxy-2,8,12-trihydroxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl) benzoate 85116048 Click to see 448.50 unknown https://doi.org/10.1021/NP030241V
(5,8-Diacetyloxy-2,12-dihydroxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl) benzoate 85110135 Click to see 490.50 unknown https://doi.org/10.1021/NP030241V
(5,8-Diacetyloxy-7-benzoyloxy-2-hydroxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-12-yl) 1-methyl-6-oxopyridine-3-carboxylate 73090926 Click to see CC(=O)OC1CCC(C23C1(C(C(C(C2OC(=O)C4=CN(C(=O)C=C4)C)C(O3)(C)C)OC(=O)C)OC(=O)C5=CC=CC=C5)C)(C)O 625.70 unknown https://doi.org/10.1021/NP030241V
(8-Acetyloxy-7-benzoyloxy-2,5-dihydroxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-12-yl) 1-methyl-6-oxopyridine-3-carboxylate 162931954 Click to see CC(=O)OC1C2C(C3(C(CCC(C3(C1OC(=O)C4=CC=CC=C4)C)O)(C)O)OC2(C)C)OC(=O)C5=CN(C(=O)C=C5)C 583.60 unknown https://doi.org/10.1055/S-2005-873186
[(1R,2R,5R,6R,7S,8R,9S,12S)-8-acetyloxy-7-benzoyloxy-2,5-dihydroxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-12-yl] 1-methyl-6-oxopyridine-3-carboxylate 162931955 Click to see 583.60 unknown https://doi.org/10.1055/S-2005-873186
[(1R,2R,6R,7S,8R,9S,12S)-12-benzoyloxy-2-hydroxy-7-(2-hydroxybenzoyl)oxy-2,6,10,10-tetramethyl-5-oxo-11-oxatricyclo[7.2.1.01,6]dodecan-8-yl] 1-methyl-6-oxopyridine-3-carboxylate 163072331 Click to see CC1(C2C(C(C3(C(=O)CCC(C3(C2OC(=O)C4=CC=CC=C4)O1)(C)O)C)OC(=O)C5=CC=CC=C5O)OC(=O)C6=CN(C(=O)C=C6)C)C 659.70 unknown https://doi.org/10.1055/S-2005-873186
[(1R,2S,5R,6R,7R,8R,9R,12R)-5,8-diacetyloxy-2,12-dihydroxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate 162848259 Click to see 490.50 unknown https://doi.org/10.1021/NP030241V
[(1R,2S,5S,6S,7S,8S,9S,12S)-5,8-diacetyloxy-7-benzoyloxy-2-hydroxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-12-yl] 1-methyl-6-oxopyridine-3-carboxylate 162946096 Click to see 625.70 unknown https://doi.org/10.1021/NP030241V
[(1S,2R,5S,6S,7S,8S,9R,12S)-12-acetyloxy-5,7-bis(furan-3-carbonyloxy)-2-hydroxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-8-yl] 1-methyl-6-oxopyridine-3-carboxylate 163080963 Click to see 667.70 unknown https://doi.org/10.1021/NP030241V
[(1S,2S,5S,6S,7R,8S,9R,12R)-12-acetyloxy-5,7-bis(furan-3-carbonyloxy)-2-hydroxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-8-yl] 1-methyl-6-oxopyridine-3-carboxylate 11490819 Click to see 667.70 unknown https://doi.org/10.1021/NP030241V
[(1S,2S,5S,6S,7S,8S,9R,12S)-5-acetyloxy-2,8,12-trihydroxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate 163046814 Click to see 448.50 unknown https://doi.org/10.1021/NP030241V
[12-Acetyloxy-5,7-bis(furan-3-carbonyloxy)-2-hydroxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-8-yl] 1-methyl-6-oxopyridine-3-carboxylate 72982070 Click to see CC(=O)OC1C2C(C(C3(C1(C(CCC3OC(=O)C4=COC=C4)(C)O)OC2(C)C)C)OC(=O)C5=COC=C5)OC(=O)C6=CN(C(=O)C=C6)C 667.70 unknown https://doi.org/10.1021/NP030241V
[12-Benzoyloxy-2-hydroxy-7-(2-hydroxybenzoyl)oxy-2,6,10,10-tetramethyl-5-oxo-11-oxatricyclo[7.2.1.01,6]dodecan-8-yl] 1-methyl-6-oxopyridine-3-carboxylate 163072330 Click to see 659.70 unknown https://doi.org/10.1055/S-2005-873186
Reissantin A 11763527 Click to see 625.70 unknown https://doi.org/10.1021/NP030241V
Reissantin D 10343634 Click to see 448.50 unknown https://doi.org/10.1021/NP030241V
reissantin E 10323282 Click to see CC(=O)OC1CCC(C23C1(C(C(C(C2O)C(O3)(C)C)OC(=O)C)OC(=O)C4=CC=CC=C4)C)(C)O 490.50 unknown https://doi.org/10.1021/NP030241V
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(2R,4aS,6aR,6aR,6bS,8aR,9R,12aS,14aS,14bR)-2,4a,6a,8a,9,12a,14a-heptamethyl-10-oxo-3,4,5,6,6a,6b,7,8,9,11,12,13,14,14b-tetradecahydro-1H-picene-2-carbaldehyde 163011728 Click to see 440.70 unknown https://doi.org/10.1021/NP030241V
(3S,4aS,6aR,6bS,8aR,12aR,14aR,14bR)-3-hydroxy-4,4,6a,6b,8a,11,11,14b-octamethyl-2,3,4a,6,7,8,9,10,12,12a,14,14a-dodecahydro-1H-picen-5-one 162918187 Click to see CC1(CCC2(CCC3(C(=CCC4C3(CC(=O)C5C4(CCC(C5(C)C)O)C)C)C2C1)C)C)C 440.70 unknown https://doi.org/10.1021/NP030241V
(3S,6aR,6bS,8aR,12aS,14aR,14bR)-3-hydroxy-4,4,6a,6b,8a,11,11,14b-octamethyl-2,3,4a,6,7,8,9,10,12,12a,14,14a-dodecahydro-1H-picen-5-one 44566912 Click to see 440.70 unknown https://doi.org/10.1021/NP030241V
(4aR,6aR,6bS,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,4a,6,7,8,9,10,12,12a,14,14a-dodecahydropicene-3,5-dione 162871286 Click to see 438.70 unknown https://doi.org/10.1021/NP030241V
(4aS,6aR,6aS,6bR,8aS,11R,12aR,14aS,14bS)-11-(hydroxymethyl)-4,4a,6a,6b,8a,11,14a-heptamethyl-2,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-tetradecahydro-1H-picen-3-one 137705381 Click to see 442.70 unknown https://doi.org/10.1021/NP030241V
(4aS,6aR,6bS,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,4a,6,7,8,9,10,12,12a,14,14a-dodecahydropicene-3,5-dione 162871287 Click to see 438.70 unknown https://doi.org/10.1021/NP030241V
(4R,4aR,6aS,6aS,6bR,8aR,12aR,14aR,14bS)-4,4a,6a,6b,8a,11,11,14b-octamethyl-2,4,5,6,6a,7,8,9,10,12,12a,13,14,14a-tetradecahydro-1H-picen-3-one 162844475 Click to see CC1C(=O)CCC2(C1(CCC3C2CCC4(C3(CCC5(C4CC(CC5)(C)C)C)C)C)C)C 426.70 unknown https://doi.org/10.1021/NP030241V
(4R,4aR,6aS,6aS,6bR,8aS,11R,12aR,14aR,14bS)-11-(hydroxymethyl)-4,4a,6a,6b,8a,11,14b-heptamethyl-2,4,5,6,6a,7,8,9,10,12,12a,13,14,14a-tetradecahydro-1H-picen-3-one 162853082 Click to see 442.70 unknown https://doi.org/10.1021/NP030241V
10-Hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid 4274774 Click to see 450.60 unknown https://doi.org/10.1021/NP030241V
11-(hydroxymethyl)-4,4a,6a,6b,8a,11,14b-heptamethyl-2,4,5,6,6a,7,8,9,10,12,12a,13,14,14a-tetradecahydro-1H-picen-3-one 162853081 Click to see 442.70 unknown https://doi.org/10.1021/NP030241V
2,4a,6a,8a,9,12a,14a-heptamethyl-10-oxo-3,4,5,6,6a,6b,7,8,9,11,12,13,14,14b-tetradecahydro-1H-picene-2-carbaldehyde 163011727 Click to see CC1C(=O)CCC2(C1(CCC3C2CCC4(C3(CCC5(C4CC(CC5)(C)C=O)C)C)C)C)C 440.70 unknown https://doi.org/10.1021/NP030241V
24-Nor-D:A-friedooleana-1(10),5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-, methyl ester 264268 Click to see CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)OC)C)C)C)C)O 464.60 unknown https://doi.org/10.1021/NP030241V
3-hydroxy-4,4,6a,6b,8a,11,11,14b-octamethyl-2,3,4a,6,7,8,9,10,12,12a,14,14a-dodecahydro-1H-picen-5-one 75072218 Click to see 440.70 unknown https://doi.org/10.1021/NP030241V
4,4,6a,6b,8a,11,11,14b-Octamethyl-1,2,4a,6,7,8,9,10,12,12a,14,14a-dodecahydropicene-3,5-dione 162871285 Click to see CC1(CCC2(CCC3(C(=CCC4C3(CC(=O)C5C4(CCC(=O)C5(C)C)C)C)C2C1)C)C)C 438.70 unknown https://doi.org/10.1021/NP030241V
4,4a,6a,6b,8a,11,11,14b-octamethyl-2,4,5,6,6a,7,8,9,10,12,12a,13,14,14a-tetradecahydro-1H-picen-3-one 162844474 Click to see CC1C(=O)CCC2(C1(CCC3C2CCC4(C3(CCC5(C4CC(CC5)(C)C)C)C)C)C)C 426.70 unknown https://doi.org/10.1021/NP030241V
Celastrol 122724 Click to see CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O 450.60 unknown https://doi.org/10.1021/NP030241V
Pristimerin 159516 Click to see 464.60 unknown https://doi.org/10.1021/NP030241V
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Stigmastanes and derivatives
(-)-beta-Sitosterol 222284 Click to see 414.70 unknown https://doi.org/10.1021/NP030241V
17-(5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 86821 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)C(C)C 414.70 unknown https://doi.org/10.1021/NP030241V
beta-Sitosterol 3-O-beta-D-galactopyranoside 296119 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C 576.80 unknown https://doi.org/10.1021/NP030241V
Sitogluside 5742590 Click to see CCC(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC5C(C(C(C(O5)CO)O)O)O)C)C)C(C)C 576.80 unknown https://doi.org/10.1021/NP030241V
Stigmast-5-en-3-ol 22012 Click to see 414.70 unknown https://doi.org/10.1021/NP030241V
> Organic acids and derivatives / Carboxylic acids and derivatives / Pentacarboxylic acids and derivatives
(5,8-Diacetyloxy-4,7-dibenzoyloxy-2-hydroxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-12-yl) 1-methyl-6-oxopyridine-3-carboxylate 85156145 Click to see CC(=O)OC1C2C(C3(C(CC(C(C3(C1OC(=O)C4=CC=CC=C4)C)OC(=O)C)OC(=O)C5=CC=CC=C5)(C)O)OC2(C)C)OC(=O)C6=CN(C(=O)C=C6)C 745.80 unknown https://doi.org/10.1021/NP030241V
[(1R,2R,5R,6R,7R,8R,9S,12S)-12-acetyloxy-6-(acetyloxymethyl)-7-benzoyloxy-5-(furan-3-carbonyloxy)-2-hydroxy-2,10,10-trimethyl-11-oxatricyclo[7.2.1.01,6]dodecan-8-yl] 1-methyl-6-oxopyridine-3-carboxylate 163018442 Click to see 735.70 unknown https://doi.org/10.1055/S-2005-873186
[(1R,2S,4R,5S,6S,7S,8S,9S,12R)-5,8-diacetyloxy-4,7-dibenzoyloxy-2-hydroxy-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.01,6]dodecan-12-yl] 1-methyl-6-oxopyridine-3-carboxylate 162952816 Click to see 745.80 unknown https://doi.org/10.1021/NP030241V
[12-Acetyloxy-6-(acetyloxymethyl)-7-benzoyloxy-5-(furan-3-carbonyloxy)-2-hydroxy-2,10,10-trimethyl-11-oxatricyclo[7.2.1.01,6]dodecan-8-yl] 1-methyl-6-oxopyridine-3-carboxylate 163018441 Click to see 735.70 unknown https://doi.org/10.1055/S-2005-873186
Reissantin B 10485185 Click to see 745.80 unknown https://doi.org/10.1021/NP030241V
> Organoheterocyclic compounds / Pyridines and derivatives / Pyridinecarboxylic acids and derivatives / Pyridinecarboxylic acids
Methyl 1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate 597449 Click to see CN1C=C(C=CC1=O)C(=O)OC 167.16 unknown https://doi.org/10.1021/NP030241V
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives
Docosyl ferulate 14238616 Click to see CCCCCCCCCCCCCCCCCCCCCCOC(=O)C=CC1=CC(=C(C=C1)O)OC 502.80 unknown https://doi.org/10.1021/NP030241V
Tetracosyl 3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate 54412038 Click to see CCCCCCCCCCCCCCCCCCCCCCCCOC(=O)C=CC1=CC(=C(C=C1)O)OC 530.80 unknown https://doi.org/10.1021/NP030241V
Tetracosyl ferulate 14238617 Click to see 530.80 unknown https://doi.org/10.1021/NP030241V
Unii-A2T8gne262 54370069 Click to see 502.80 unknown https://doi.org/10.1021/NP030241V

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