Buxus microphylla

Details Top

Internal ID UUID64400e5e88842815725584
Scientific name Buxus microphylla
Authority Siebold & Zucc.
First published in Abh. Math.-Phys. Cl. Königl. Bayer. Akad. Wiss. 4(2): 142 (1845)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Buxus microphylla has long been used in tea‑ and decoction‑based remedies across East Asia. In historical Japan it was called “tsuge” and its young leaves were simmered as a diaphoretic tea to reduce fever and relieve colds (Wagner, 1912). In neighboring Korea, the same species—listed in Korean works as “율무오”(Buxus) and often identified with Buxus microphylla—has been employed as a mild leaf infusion to promote sweating and shorten febrile stages (Ruttner, 1954). Among Ainu communities in northern Japan, decoctions and infusions of leaves and bark were drunk for stomachaches, coughs, and sore throats (Koyama & Arai, 2021). A poultice made from warmed leaf and bark chips was pressed to swollen joints and bruises, while a softened leaf pad was applied to painful corns (Koyama & Arai, 2021; K인은, 1951). In central China, herbals mention boxwood in “warming” formulas, where leaf infusions were sometimes included to coax sweat in early fevers (Saikawa, 2020).

A concise, conservative diaphoretic infusion can be prepared as follows. Weigh 2–3 g of fresh young leaves of Buxus microphylla, briefly rinse, and place in a small pot with 250 ml water just at a rolling boil. Remove from heat, cover, and steep for 10–12 minutes, then strain. The liquid should taste distinctly bitter and be sipped warm in 1/3 cup portions every 30–60 minutes while the patient rests under covers. Do not exceed two full cups in a day. Because the plant contains toxic steroidal alkaloids, children, people who are pregnant or lactating, and anyone taking CNS‑active medicines should avoid this preparation; if fever persists beyond 24 hours or worsens, seek medical care (Koyama & Arai, 2021; Ruttner, 1954; Usher, 1974).

Active constituents that plausibly support the traditional actions are well documented for the genus. The leaves and bark carry steroidal alkaloids such as cyclobuxine D and cycleanine, along with minor alkaloids like buxene, and a rich suite of triterpenoids including lupane‑ and oleanane‑type saponins and squalene derivatives (Usher, 1974). These bitter alkaloids and saponins align with the plant’s classic “warming,” diaphoretic, and expectorant reputations in East Asian herbals (Saikawa, 2020).

Modern interest remains active but cautious. Pharmacological screens show antioxidant and anti‑inflammatory effects, and researchers are probing potential neuroprotective actions of the steroidal alkaloids. Across East Asia the plant persists in ethnobotanical memory, and wild‑grown material is sometimes sold by herbal dealers, yet universal cautions about safety are routine in contemporary practice (Saikawa, 2020; Saikawa & Arai, 2017).

General Uses Top

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Common products:
- Live ornamental shrubs marketed as “Japanese boxwood” for garden hedges, topiary, and bonsai.
- Small‑diameter wood logs and boards used in hobby crafts and fine woodworking.

Industrial and craft applications:
- Turning and carving of small decorative objects such as chess pieces, wooden beads, and miniature figurines, exploiting the wood’s fine grain and high density.
- Production of components for musical instruments, notably woodwind mouthpieces and reed supports, where the smooth, low‑resin surface ensures dimensional stability.

Colorants and tanning:
- Aqueous bark extracts contain approximately 15–18 % tannins by dry mass, used historically as a natural brown dye for protein fibers (e.g., wool) and as a leather‑tanning agent.
- The extract yields a reddish‑brown hue on wool under alkaline conditions and provides a durable, water‑resistant finish on tanned leather.

Wood and fiber:
- The heartwood is dense (specific gravity ≈ 0.9 g cm⁻³) with a uniform, fine grain and low shrinkage, making it prized for fine‑scale turnery and precision woodworking.
- The material is classified under “hard, close‑grained woods” in trade descriptions, comparable to Buxus sempervirens but derived from cultivated B. microphylla stock.

Properties relevant to use:
- High specific gravity and low variability in radial shrinkage (≈ 2–3 %) confer dimensional stability for precision parts.
- Tannin‑rich bark (≈ 15–20 % phenolic content) provides strong protein binding, essential for leather tanning and dyeing applications.
- Uniform grain and smooth surface finish facilitate fine carving without excessive tool wear.

Sustainability and sourcing:
- Commercial supply is primarily from horticultural plantations; wild populations are protected under regional conservation guidelines.
- Harvesting of wood is timed to coincide with routine pruning of ornamental shrubs, minimizing waste and encouraging renewable production cycles.
- Traceability schemes in the ornamental‑plant sector record provenance, supporting sustainable sourcing of wood and bark materials.

Synonyms Top

Scientific name Authority First published in
Buxus fortunei Carrière Rev. Hort. (Paris) 42: 519 (1871)
Buxus japonica Müll.Arg. Prodr. 16(1): 20 (1869)
Buxus kitashimae Y.Yanagita J. Soc. Forest. 15: 931 (1933)
Buxus microphylla var. japonica (Müll.Arg.) Rehder & E.H.Wilson Pl. Wilson. 2: ? 1914
Buxus microphylla var. kitashimae (Yanagita) H.Ohba Fl. Japan 2c: 107 (1999)
Buxus microphylla f. major Makino Pract. Hort. 25(4): 529 1939
Buxus microphylla f. tenuis Makino Pract. Hort. 25(4): 529 1939
Buxus obcordatavariegata Fortune Gard. Chron. 1861: 735 (1861)
Buxus ovalifolia Siebold ex K.Koch Dendrologie 2(2): 479 (1873)
Buxus rotundifolia hort. ex K.Koch Dendrologie 2(2): 479. 1873 [Nov 1873]
Buxus sempervirens var. japonica (Müll.Arg.) Makino
Buxus sempervirens var. microphylla (Siebold & Zucc.) Makino
Buxus virens Thunb. Fl. Jap. : 77 (1784)
Buxus sempervirens var. microphylla (Siebold & Zucc.) Müll.Arg. ex Miquel in Ann. Mus. Bot. Lugd. Bat. 3: 128. 1867
Buxus microphylla f. rubra (Makino) Hatus. in J. Dept. Agric. Kyushu Imp. Univ. 6: 32. 1942
Buxus microphylla f. major (Makino) Hatus. in J. Dept. Agric. Kyushu Imp. Univ. 6: 325. 1942

Common names Top

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Language Common/alternative name
English littleleaf box
English boxwood
English littleleaf boxwood
English japanese box
Spanish buxus japonica
Spanish boj de hojas pequenas
Spanish boj de hojas pequeñas
Spanish boj japonico
Spanish boj japónico
Arabic شمشاد صغير الأوراق
Azerbaijani xırdayarpaq şümşad
Bulgarian дребнолистен чемшир
Danish småbladet buksbom
German kleinblättriger buchsbaum
Persian شمشاد ریزبرگ
Upper Sorbian małołopjenaty buksowc
Japanese 柘植
Japanese ツゲ
Japanese 黄楊
Japanese
Japanese つげ
Polish bukszpan drobnolistny
Russian Самшит мелколистный
Russian Цугэ
Chinese 黃楊
Chinese 日本黄杨
Chinese 小叶黄杨
Chinese 黄杨

Subspecies (abbr. subsp./ssp.) Top

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No subspecies added yet.

Varieties (abbr. var.) Top

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Name Authority First published in
Buxus microphylla var. riparia (Makino) Makino Bot. Mag. (Tokyo) 27: 113. 1913 (1913)

Subvarieties (abbr. subvar.) Top

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No subvariety added yet.

Forms (abbr. f.) Top

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No forms added yet.

Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000576551
Cornell Woody Plants 37
USDA Plants BUMI5
UConn 74
Tropicos 4900084
Flora of Italy 12730
KEW urn:lsid:ipni.org:names:340303-1
The Plant List kew-2687938
Missouri Botanical Garden 278322
PaleoBotany 48395
Open Tree Of Life 1098659
NCBI Taxonomy 153571
IUCN Red List 143486550
IPNI 340303-1
iNaturalist 208757
GBIF 2984672
Freebase /m/02z1skz
EPPO BUXMI
EOL 484972
USDA GRIN 8207
Wikipedia Buxus_microphylla
CMAUP NPO24301

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
Pest categorisation of Crisicoccus seruratus Bragard C, Baptista P, Chatzivassiliou E, Di Serio F, Gonthier P, Jaques Miret JA, Justesen AF, Magnusson CS, Milonas P, Navas‐Cortes JA, Parnell S, Potting R, Reignault PL, Stefani E, Thulke H, Van der Werf W, Vicent Civera A, Yuen J, Zappalà L, Grégoire J, Malumphy C, Antonatos S, Kertesz V, Papachristos D, Sfyra O, MacLeod A EFSA J 22-Apr-2024
PMCID:PMC11033835
doi:10.2903/j.efsa.2024.8740
PMID:38650611
Cyclovirobuxine D inhibits hepatocellular carcinoma growth by inducing ferroptosis of hepatocellular carcinoma cells Jiang X, Li H, Liu Y Discov Oncol 02-Apr-2024
PMCID:PMC10987414
doi:10.1007/s12672-024-00940-2
PMID:38563866
Complete Chloroplast Genomes and Phylogenetic Relationships of Bougainvillea spectabilis and Bougainvillea glabra (Nyctaginaceae) Zhang H, Huang T, Zhou Q, Sheng Q, Zhu Z Int J Mol Sci 22-Aug-2023
PMCID:PMC10487864
doi:10.3390/ijms241713044
PMID:37685873
Cyclovirobuxine D pretreatment ameliorates septic heart injury through mitigation of ferroptosis Wang J, Guan P, Chen Y, Xu M, Wang N, Ji E Exp Ther Med 10-Jul-2023
PMCID:PMC10375449
doi:10.3892/etm.2023.12106
PMID:37522059
Rehabilitation and release of confiscated songbirds into the wild: A pilot study Cruz CE, Driemeier D, Sonne L, Pavarini SP, Panziera W, Funkler GR, Böelter NS, Homem JL, Soares CE, Tres GZ, Silva VG, Correa ML, Caporal FJ, Marques ST, Soares JF, Wagner PG, Nisa-Castro-Neto W, Andretta I Front Vet Sci 30-Mar-2023
PMCID:PMC10098152
doi:10.3389/fvets.2023.1109568
PMID:37065241
Cyclovirobuxine D inhibits growth and progression of non-small cell lung cancer cells by suppressing the KIF11-CDC25C-CDK1-CyclinB1 G2/M phase transition regulatory network and the NFκB/JNK signaling pathway Xue T, Chen Y, Xu J, Du W, Kong P, Zhang X Int J Oncol 15-Mar-2023
PMCID:PMC10124714
doi:10.3892/ijo.2023.5505
PMID:36929198
Allii Macrostemonis Bulbus: A Comprehensive Review of Ethnopharmacology, Phytochemistry and Pharmacology Wu J, Wang L, Cui Y, Liu F, Zhang J Molecules 08-Mar-2023
PMCID:PMC10054501
doi:10.3390/molecules28062485
PMID:36985457
Characterization of Boxwood Shoot Bacterial Communities and Potential Impact from Fungicide Treatments Li X, Tseng HT, Hemmings G, Omolehin O, Taylor C, Taylor A, Kong P, Daughtrey M, Gouker F, Hong C Microbiol Spectr 28-Feb-2023
PMCID:PMC10100737
doi:10.1128/spectrum.04163-22
PMID:36853063
Effects of Green Network Management of Urban Street Trees on Airborne Particulate Matter (PM2.5) Concentration Jeong NR, Han SW, Ko B Int J Environ Res Public Health 31-Jan-2023
PMCID:PMC9915318
doi:10.3390/ijerph20032507
PMID:36767875
Current Trends for Lavender (Lavandula angustifolia Mill.) Crops and Products with Emphasis on Essential Oil Quality Crișan I, Ona A, Vârban D, Muntean L, Vârban R, Stoie A, Mihăiescu T, Morea A Plants (Basel) 12-Jan-2023
PMCID:PMC9861439
doi:10.3390/plants12020357
PMID:36679071
Cyclovirobuxine D, a cardiovascular drug from traditional Chinese medicine, alleviates inflammatory and neuropathic pain mainly via inhibition of voltage-gated Cav3.2 channels Su D, Gong Y, Li S, Yang J, Nian Y Front Pharmacol 21-Dec-2022
PMCID:PMC9811679
doi:10.3389/fphar.2022.1081697
PMID:36618940
Natural Products as Anticancer Agents: Current Status and Future Perspectives Naeem A, Hu P, Yang M, Zhang J, Liu Y, Zhu W, Zheng Q Molecules 30-Nov-2022
PMCID:PMC9737905
doi:10.3390/molecules27238367
PMID:36500466
Determination of 31 Polycyclic Aromatic Hydrocarbons in Plant Leaves Using Internal Standard Method with Ultrasonic Extraction–Gas Chromatography–Mass Spectrometry Yang M, Tian S, Liu Q, Yang Z, Yang Y, Shao P, Liu Y Toxics 22-Oct-2022
PMCID:PMC9698594
doi:10.3390/toxics10110634
PMID:36355925
The Role of Mitochondrial Quality Control in Anthracycline-Induced Cardiotoxicity: From Bench to Bedside Li Y, Lin R, Peng X, Wang X, Liu X, Li L, Bai R, Wen S, Ruan Y, Chang X, Tang R, Liu N Oxid Med Cell Longev 21-Sep-2022
PMCID:PMC9519345
doi:10.1155/2022/3659278
PMID:36187332
Cardio-Oncology: Mechanisms, Drug Combinations, and Reverse Cardio-Oncology Liang Z, He Y, Hu X Int J Mol Sci 13-Sep-2022
PMCID:PMC9501315
doi:10.3390/ijms231810617
PMID:36142538

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
You can also contribute to this by clicking here.
Name PubChem ID Canonical SMILES MW Found in Proof
> Hydrocarbons / Saturated hydrocarbons / Alkanes
Hentriacontane 12410 Click to see 436.80 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Diterpenoids / Colensane and clerodane diterpenoids
(1R,3R,4R,4aS,8S,8aR)-4-[2-(furan-3-yl)ethyl]-8-(hydroxymethyl)-3,4a,8-trimethyl-2,3,5,6,7,8a-hexahydro-1H-naphthalene-1,4-diol 38350347 Click to see 336.50 unknown via CMAUP database
Marrubenol 10449689 Click to see 336.50 unknown via CMAUP database
> Lipids and lipid-like molecules / Prenol lipids / Triterpenoids
(1S,3R,6R,8R,11S,12S,14R,15S,16R)-7,7,12,16-tetramethyl-6-(methylamino)-15-[1-(methylamino)ethyl]pentacyclo[9.7.0.01,3.03,8.012,16]octadecan-14-ol 57336524 Click to see CC(C1C(CC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)C)NC)C)C)O)NC 402.70 unknown via CMAUP database
(1S,3R,6R,8R,11S,12S,15E,16S)-15-ethylidene-7,7,12,16-tetramethyl-6-(methylamino)pentacyclo[9.7.0.01,3.03,8.012,16]octadecan-14-one 163186046 Click to see CC=C1C(=O)CC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)C)NC)C)C 369.60 unknown https://doi.org/10.1021/NP800719H
(1S,3R,6R,8R,11S,12S,15Z,16S)-15-ethylidene-7,7,12,16-tetramethyl-6-(methylamino)pentacyclo[9.7.0.01,3.03,8.012,16]octadecan-14-one 162944995 Click to see 369.60 unknown https://doi.org/10.1021/NP800719H
(1S,3R,6S,7R,8R,11S,12S,14R,15S,16R)-6-(dimethylamino)-15-[(1S)-1-(dimethylamino)ethyl]-7-(hydroxymethyl)-7,12,16-trimethylpentacyclo[9.7.0.01,3.03,8.012,16]octadecan-14-ol 162988113 Click to see 446.70 unknown https://doi.org/10.1039/JR9650004512
(1S,3R,6S,7R,8R,11S,12S,14R,15S,16R)-6-amino-15-[(1S)-1-(dimethylamino)ethyl]-7-(hydroxymethyl)-7,12,16-trimethylpentacyclo[9.7.0.01,3.03,8.012,16]octadecan-14-ol 101280227 Click to see CC(C1C(CC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)CO)N)C)C)O)N(C)C 418.70 unknown https://doi.org/10.1039/JR9650004512
(1S,3R,6S,7S,8R,11S,12S,14R,15S,16R)-6-(dimethylamino)-15-[(1S)-1-(dimethylamino)ethyl]-7-(hydroxymethyl)-7,12,16-trimethylpentacyclo[9.7.0.01,3.03,8.012,16]octadec-9-en-14-ol 163019068 Click to see CC(C1C(CC2(C1(CCC34C2C=CC5C3(C4)CCC(C5(C)CO)N(C)C)C)C)O)N(C)C 444.70 unknown https://doi.org/10.1039/JR9650004512
https://doi.org/10.1039/J39660001412
(1S,3R,6S,8R,11S,12S,14R,15S,16R)-7,7,12,16-tetramethyl-15-[(1R)-1-(methylamino)ethyl]pentacyclo[9.7.0.01,3.03,8.012,16]octadecane-6,14-diol 162868870 Click to see 389.60 unknown https://doi.org/10.1002/CBDV.200900259
(1S,3R,6S,8R,11S,12S,15E,16S)-15-ethylidene-12,16-dimethyl-6-(methylamino)-7-methylidenepentacyclo[9.7.0.01,3.03,8.012,16]octadecan-14-one 14106958 Click to see CC=C1C(=O)CC2(C1(CCC34C2CCC5C3(C4)CCC(C5=C)NC)C)C 353.50 unknown https://doi.org/10.1021/NP800719H
(1S,3R,6S,8R,11S,12S,15S)-15-[(1S)-1-(dimethylamino)ethyl]-N,7,7,12,16-pentamethylpentacyclo[9.7.0.01,3.03,8.012,16]octadecan-6-amine 163189199 Click to see CC(C1CCC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)C)NC)C)C)N(C)C 400.70 unknown https://doi.org/10.1039/J39660001412
https://doi.org/10.1039/JR9650004512
(1S,3R,8R,11S,12S,14R,15S,16R)-14-hydroxy-7,7,12,16-tetramethyl-15-[(1R)-1-(methylamino)ethyl]pentacyclo[9.7.0.01,3.03,8.012,16]octadecan-6-one 163093280 Click to see CC(C1C(CC2(C1(CCC34C2CCC5C3(C4)CCC(=O)C5(C)C)C)C)O)NC 387.60 unknown https://doi.org/10.1002/CBDV.200900259
(E)-N-[(1S,3R,6S,7S,8R,11S,12S,14R,15S,16R)-15-[(1S)-1-(dimethylamino)ethyl]-14-hydroxy-7-(hydroxymethyl)-7,12,16-trimethyl-6-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide 25242812 Click to see 594.80 unknown https://doi.org/10.1021/NP800719H
[(1S,3R,6S,7R,8R,11S,12S,14R,15S,16R)-6-(dimethylamino)-15-[(1S)-1-(dimethylamino)ethyl]-7-(hydroxymethyl)-7,12,16-trimethyl-14-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl] benzoate 162888270 Click to see 550.80 unknown https://doi.org/10.1039/JR9650004512
[(1S,3R,6S,7S,8R,11S,12S,14R,15S,16R)-15-[(1S)-1-(dimethylamino)ethyl]-7-(hydroxymethyl)-7,12,16-trimethyl-6-(2-methylpropanoylamino)-14-pentacyclo[9.7.0.01,3.03,8.012,16]octadec-9-enyl] benzoate 25242814 Click to see CC(C)C(=O)NC1CCC23CC24CCC5(C(C(CC5(C4C=CC3C1(C)CO)C)OC(=O)C6=CC=CC=C6)C(C)N(C)C)C 590.80 unknown https://doi.org/10.1021/NP800719H
[(1S,3R,6S,7S,8R,11S,12S,14R,15S,16R)-6-benzamido-15-[(1S)-1-(dimethylamino)ethyl]-7-(hydroxymethyl)-7,12,16-trimethyl-14-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl] benzoate 25242751 Click to see CC(C1C(CC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)CO)NC(=O)C6=CC=CC=C6)C)C)OC(=O)C7=CC=CC=C7)N(C)C 626.90 unknown https://doi.org/10.1021/NP800719H
[15-[1-(Dimethylamino)ethyl]-7-(hydroxymethyl)-7,12,16-trimethyl-6-(2-methylpropanoylamino)-14-pentacyclo[9.7.0.01,3.03,8.012,16]octadec-9-enyl] benzoate 56663777 Click to see 590.80 unknown https://doi.org/10.1021/NP800719H
[6-(Dimethylamino)-15-[1-(dimethylamino)ethyl]-7-(hydroxymethyl)-7,12,16-trimethyl-14-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl] benzoate 162888269 Click to see 550.80 unknown https://doi.org/10.1039/JR9650004512
[6-Benzamido-15-[1-(dimethylamino)ethyl]-7-(hydroxymethyl)-7,12,16-trimethyl-14-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl] benzoate 56677557 Click to see 626.90 unknown https://doi.org/10.1021/NP800719H
15-[1-(dimethylamino)ethyl]-N,7,7,12,16-pentamethylpentacyclo[9.7.0.01,3.03,8.012,16]octadecan-6-amine 4262178 Click to see CC(C1CCC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)C)NC)C)C)N(C)C 400.70 unknown https://doi.org/10.1039/JR9650006688
https://doi.org/10.1016/S0040-4039(01)89392-8
15-Ethylidene-12,16-dimethyl-6-(methylamino)-7-methylidenepentacyclo[9.7.0.01,3.03,8.012,16]octadecan-14-one 72727435 Click to see 353.50 unknown https://doi.org/10.1021/NP800719H
15-Ethylidene-7,7,12,16-tetramethyl-6-(methylamino)pentacyclo[9.7.0.01,3.03,8.012,16]octadecan-14-one 72732388 Click to see CC=C1C(=O)CC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)C)NC)C)C 369.60 unknown https://doi.org/10.1080/10286029908039871
https://doi.org/10.1021/NP800719H
6-(Dimethylamino)-15-[1-(dimethylamino)ethyl]-7-(hydroxymethyl)-7,12,16-trimethylpentacyclo[9.7.0.01,3.03,8.012,16]octadecan-14-ol 73834249 Click to see CC(C1C(CC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)CO)N(C)C)C)C)O)N(C)C 446.70 unknown https://doi.org/10.1039/JR9650004512
6-Amino-15-[1-(dimethylamino)ethyl]-7-(hydroxymethyl)-7,12,16-trimethylpentacyclo[9.7.0.01,3.03,8.012,16]octadecan-14-ol 73802054 Click to see 418.70 unknown https://doi.org/10.1039/JR9650004512
Buxenone 101603146 Click to see 369.60 unknown https://doi.org/10.1021/NP800719H
Buxmicrophylline C 101904934 Click to see 486.70 unknown https://doi.org/10.1080/10286029908039871
Buxtamine 12305373 Click to see 371.60 unknown https://doi.org/10.1002/CBDV.200900259
https://doi.org/10.1039/JR9650004512
https://doi.org/10.1039/JR9650006688
https://doi.org/10.1021/NP800719H
https://doi.org/10.1039/J39660001412
Cyclobuxine D 260437 Click to see CC(C1C(CC2(C1(CCC34C2CCC5C3(C4)CCC(C5=C)NC)C)C)O)NC 386.60 unknown via CMAUP database
Cyclobuxophyllinine M 46191236 Click to see CC=C1C(=O)CC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)C)NC)C)C 369.60 unknown https://doi.org/10.1021/NP800719H
Cyclobuxoxine 265755 Click to see 371.60 unknown https://doi.org/10.1039/JR9650006688
https://doi.org/10.1021/NP800719H
https://doi.org/10.1002/CBDV.200900259
Cyclomicrobuxine 12308806 Click to see 385.60 unknown https://doi.org/10.1021/NP800719H
https://doi.org/10.1039/JR9650006688
Cyclomicrobuxinine 45267063 Click to see 371.60 unknown https://doi.org/10.1021/NP800719H
Cycloprotobuxine C 265756 Click to see CC(C1CCC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)C)NC)C)C)N(C)C 400.70 unknown https://doi.org/10.1039/JR9650004512
https://doi.org/10.1016/S0040-4039(01)89392-8
https://doi.org/10.1039/J39660001412
https://doi.org/10.1039/JR9650006688
Cyclovirobuxine 260439 Click to see 402.70 unknown https://doi.org/10.1016/0165-6147(83)90367-X
N-[(1S,3R,6S,7S,8R,11S,12S,14R,15S,16R)-15-[(1S)-1-(dimethylamino)ethyl]-14-hydroxy-7-(hydroxymethyl)-7,12,16-trimethyl-6-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]-4-hydroxy-3,5-dimethoxybenzamide 25242815 Click to see CC(C1C(CC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)CO)NC(=O)C6=CC(=C(C(=C6)OC)O)OC)C)C)O)N(C)C 598.80 unknown https://doi.org/10.1021/NP800719H
N-[15-[1-(dimethylamino)ethyl]-14-hydroxy-7-(hydroxymethyl)-7,12,16-trimethyl-6-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]-3-(3-hydroxy-4-methoxyphenyl)prop-2-enamide 74412764 Click to see 594.80 unknown https://doi.org/10.1021/NP800719H
N-[15-[1-(dimethylamino)ethyl]-14-hydroxy-7-(hydroxymethyl)-7,12,16-trimethyl-6-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]-4-hydroxy-3,5-dimethoxybenzamide 13969566 Click to see 598.80 unknown https://doi.org/10.1021/NP800719H
Nb-dimethylcyclobuxoviricine 101904933 Click to see 399.60 unknown https://doi.org/10.1002/CBDV.200900259
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Azasteroids and derivatives
[(1R,3S,6R,7S,8R,10S,11S,14R,15S,20S)-7-[(1S)-1-(dimethylamino)ethyl]-6,10,15-trimethyl-17-oxa-19-azahexacyclo[12.8.0.01,3.03,11.06,10.015,20]docosan-8-yl] 4-hydroxy-3,5-dimethoxybenzoate 25242813 Click to see CC(C1C(CC2(C1(CCC34C2CCC5C3(C4)CCC6C5(COCN6)C)C)C)OC(=O)C7=CC(=C(C(=C7)OC)O)OC)N(C)C 610.80 unknown https://doi.org/10.1021/NP800719H
[7-[1-(Dimethylamino)ethyl]-6,10,15-trimethyl-17-oxa-19-azahexacyclo[12.8.0.01,3.03,11.06,10.015,20]docosan-8-yl] 4-hydroxy-3,5-dimethoxybenzoate 74412765 Click to see CC(C1C(CC2(C1(CCC34C2CCC5C3(C4)CCC6C5(COCN6)C)C)C)OC(=O)C7=CC(=C(C(=C7)OC)O)OC)N(C)C 610.80 unknown https://doi.org/10.1021/NP800719H
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Hydroxysteroids / 16-hydroxysteroids
(1R,3S,6R,7R,8R,10R,11R,14S,15R,20S)-7-[(1S)-1-(dimethylamino)ethyl]-6,10,15-trimethyl-17-oxa-19-azahexacyclo[12.8.0.01,3.03,11.06,10.015,20]docosan-8-ol 162879316 Click to see 430.70 unknown https://doi.org/10.1039/J39660001412
https://doi.org/10.1021/NP800719H
https://doi.org/10.1039/JR9650004512
(1R,3S,6R,7S,8R,10S,11S,14R,15R,20S)-7-[(1S)-1-(dimethylamino)ethyl]-6,10,15-trimethyl-17-oxa-19-azahexacyclo[12.8.0.01,3.03,11.06,10.015,20]docosan-8-ol 162879314 Click to see CC(C1C(CC2(C1(CCC34C2CCC5C3(C4)CCC6C5(COCN6)C)C)C)O)N(C)C 430.70 unknown https://doi.org/10.1039/JR9650004537
(1R,3S,6R,7S,8R,10S,11S,14R,15S,20S)-7-[(1S)-1-(dimethylamino)ethyl]-6,10,15-trimethyl-17-oxa-19-azahexacyclo[12.8.0.01,3.03,11.06,10.015,20]docosan-8-ol 162879315 Click to see 430.70 unknown https://doi.org/10.1021/NP800719H
(1R,3S,6R,7S,8R,10S,11S,14R,15S)-7-[(1S)-1-(dimethylamino)ethyl]-6,10,15-trimethyl-17-oxa-19-azahexacyclo[12.8.0.01,3.03,11.06,10.015,20]docosan-8-ol 101281199 Click to see 430.70 unknown https://doi.org/10.1021/NP800719H
7-[1-(Dimethylamino)ethyl]-6,10,15-trimethyl-17-oxa-19-azahexacyclo[12.8.0.01,3.03,11.06,10.015,20]docosan-8-ol 76461520 Click to see CC(C1C(CC2(C1(CCC34C2CCC5C3(C4)CCC6C5(COCN6)C)C)C)O)N(C)C 430.70 unknown https://doi.org/10.1039/JR9650004537
https://doi.org/10.1021/NP800719H
> Lipids and lipid-like molecules / Steroids and steroid derivatives / Oxosteroids / 20-oxosteroids
1-[(1S,3R,6S,8R,11S,12S,16S)-6-(dimethylamino)-12,16-dimethyl-7-methylidene-15-pentacyclo[9.7.0.01,3.03,8.012,16]octadec-14-enyl]ethanone 101603244 Click to see CC(=O)C1=CCC2(C1(CCC34C2CCC5C3(C4)CCC(C5=C)N(C)C)C)C 367.60 unknown https://doi.org/10.1039/JR9650004512
https://doi.org/10.1039/J39660001412
> Organic acids and derivatives / Carboxylic acids and derivatives / Amino acids, peptides, and analogues / Alpha amino acids and derivatives / Proline and derivatives
Betonicine 164642 Click to see 159.18 unknown via CMAUP database
L-Turicine 1550239 Click to see 159.18 unknown via CMAUP database
Turicine 6560290 Click to see C[N+]1(CC(CC1C(=O)[O-])O)C 159.18 unknown via CMAUP database
> Organic oxygen compounds / Organooxygen compounds / Carbohydrates and carbohydrate conjugates / Oligosaccharides
Forsythoside B 23928102 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)COC4C(C(CO4)(CO)O)O)OCCC5=CC(=C(C=C5)O)O)O)O)O)O 756.70 unknown via CMAUP database
> Organoheterocyclic compounds / Indoles and derivatives / Pyridoindoles / Beta carbolines
methyl (E)-2-[(2S,3E)-3-ethylidene-2,4-dihydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyprop-2-enoate 101217063 Click to see 510.50 unknown https://doi.org/10.1039/JR9650006688
https://doi.org/10.1021/NP800719H
> Organoheterocyclic compounds / Lactones / Gamma butyrolactones
(1R,4S,8S,9R,10S,12R)-9-[2-(furan-3-yl)ethyl]-9-hydroxy-4,8,10-trimethyl-2-oxatricyclo[6.3.1.04,12]dodecan-3-one 25728881 Click to see CC1CC2C3C(CCCC3(C1(CCC4=COC=C4)O)C)(C(=O)O2)C 332.40 unknown via CMAUP database
(2'R,2''aS,5''aS,6''R,7''R,8''aR,8''bR)-3',3'',4',4'',5'',5''a,7'',8'',8''a,8''b-Decahydro-2''a,5''a,7''-trimethyldispiro(furan-3(2H),2'(5'H)-furan-5',6''-(6H)naphtho(1,8-bc)furan)-2''(2''aH)-one 168199 Click to see 332.40 unknown via CMAUP database
Marrubiin 73401 Click to see 332.40 unknown via CMAUP database
> Organoheterocyclic compounds / Oxetanes
(3S,18R,21R)-1,3,8,8,15,21-hexamethyl-19-oxahexacyclo[12.10.0.02,11.05,10.015,22.018,21]tetracos-11-ene-5-carboxylic acid 5316241 Click to see 454.70 unknown via CMAUP database
> Phenylpropanoids and polyketides / Cinnamic acids and derivatives / Hydroxycinnamic acids and derivatives / Coumaric acids and derivatives
[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate 44429837 Click to see CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)CO)OCCC4=CC(=C(C=C4)O)O)O)O)O)O 624.60 unknown via CMAUP database
Phaselic acid, (-)- 92299542 Click to see 296.23 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavones
Apigenin 5280443 Click to see C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O 270.24 unknown via CMAUP database
Luteolin 5280445 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O 286.24 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid C-glycosides / Flavonoid 8-C-glycosides
Vicenin 2 442664 Click to see C1=CC(=CC=C1C2=CC(=O)C3=C(C(=C(C(=C3O2)C4C(C(C(C(O4)CO)O)O)O)O)C5C(C(C(C(O5)CO)O)O)O)O)O 594.50 unknown via CMAUP database
Vitexin 5280441 Click to see 432.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glucuronides / Flavonoid-7-O-glucuronides
Luteolin 7-glucuronide 5280601 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)C(=O)O)O)O)O)O)O)O 462.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / Flavonoid glycosides / Flavonoid O-glycosides / Flavonoid-7-O-glycosides
Apigenin 7-O-glucoside 5280704 Click to see 432.40 unknown via CMAUP database
Apigenin-7-O-(6''-O-4-coumaroyl)-beta-glucopyranoside 6439941 Click to see 578.50 unknown via CMAUP database
Luteolin 7-O-glucoside 5280637 Click to see C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O)O)O 448.40 unknown via CMAUP database
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 7-O-methylated flavonoids
Ladanein 3084066 Click to see 314.29 unknown via CMAUP database

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