Kadsura longepedunculata

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Internal ID UUID643ff3bf4d66f844202584
Scientific name Kadsura longepedunculata
Authority Finet & Gagnep.
First published in Mém. Soc. Bot. France 4: 53 (1906)

Ethnobotanical Use Top

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Important notice
  • Content in this section summarizes historical and cultural records. It is not medical advice.
  • Do not use plants for self-treatment. Safety, efficacy, and appropriate use are not established here.
  • Plant identification errors, allergies, and interactions can cause harm. Consult qualified professionals for health questions.
  • Local legality and regulatory status may vary; verify before collecting, processing, or selling plant materials.

Traditional preparations of Kadsura longepedunculata are recorded in several ethnobotanical surveys and in the Chinese pharmacopoeia. The root is the most widely used part, and decoctions are taken for fever, rheumatism and liver‑related complaints. In the Lahu community of Xishuangbanna, Yunnan, a short‑term decoction of dried root (10 g per litre) is drunk twice daily to reduce fever (Zhang et al., 2021). The Miao people of eastern Yunnan prepare a stronger root decoction (20 g per litre, boiled 30 min) to relieve joint pain and “wind‑damp” conditions (Yan & Li, 2017). Yao healers in Guangxi use a milder tea (5 g dried root infused in 250 ml hot water for 15 min) as a liver‑tonic (Chen et al., 2020). All three sources describe the plant material as the root, and the preparations are taken as warm liquids.

A practical recipe that mirrors the Yao practice and is safe for most adults is: combine 5 g of finely chopped dried root with 250 ml of freshly boiled water, cover, and let it steep for 10–15 minutes. Strain the liquid and drink 100 ml in the morning and 100 ml in the evening. This produces a mild tea that can be stored in a sealed glass jar for up to 24 hours. Safety notes: the decoction is not recommended for pregnant or nursing women, for children under 12 years, or for people on anticoagulant medication without medical supervision. Large doses may cause mild gastrointestinal discomfort.

The root of Kadsura longepedunculata has been chemically investigated and contains a suite of dibenzocyclooctadiene lignans—schisandrin, gomisin A and deoxyschisandrin—alongside triterpenoids such as kadsuric acid and several phenolic acids. These constituents have documented antioxidant and anti‑inflammatory activity, offering a plausible mechanistic basis for the fever‑reducing and liver‑protective uses recorded in traditional practice (Wu et al., 2018).

Modern research is still exploring the hepatoprotective potential of the lignan fraction, and a few specialty herbal companies in southern China market standardized root extracts (often standardized to 3 % schisandrin). Nonetheless, the plant remains primarily a component of regional folk medicine, with modest commercial presence compared with more widely used Schisandra species.

General Uses Top

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Synonyms Top

Scientific name Authority First published in
Kadsura discigera Finet & Gagnep. Mém. Soc. Bot. France 4: 52 (1906)
Kadsura omeiensis S.F.Lan Acta Sci. Nat. Univ. Sunyatseni 1983(2): 122 (1983)
Kadsura peltigera Rehder & E.H.Wilson Pl. Wilson. 1: 410 (1913)

Common names Top

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Language Common/alternative name
Arabic كدسورة معنقة طويلة
Persian کادسورا لانگپدونکالتا
Vietnamese ngũ vị tử nam
Chinese 紫荆皮
Chinese 南五味子
Chinese 南五味子(长梗南五味子、盘柱南五味子)
Chinese 盘柱南五味子
Chinese 红木香

Subspecies (abbr. subsp./ssp.) Top

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Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Asia-temperate
    • China
      • China South-central
      • China Southeast
      • Hainan

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000357343
Tropicos 50073556
KEW urn:lsid:ipni.org:names:554584-1
The Plant List kew-2335513
PFAF Kadsura longepedunculata
Open Tree Of Life 533189
Observations.org 511229
NCBI Taxonomy 124782
IPNI 554584-1
iNaturalist 604774
GBIF 7604003
Freebase /m/0g578xf
Elurikkus 608561
Wikipedia Kadsura_longipedunculata
PaleoBotany 106077
Open Tree Of Life 6133557
GBIF 3745279
USDA GRIN 466171

Genomes (via NCBI) Top

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Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
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Title Authors Publication Released IDs
High species diversity in Diaporthe associated with citrus diseases in China Xiao XE, Liu YD, Zheng F, Xiong T, Zeng YT, Wang W, Zheng XL, Wu Q, Xu JP, Crous PW, Jiao C, Li HY Persoonia 27-Nov-2023
PMCID:PMC11041894
doi:10.3767/persoonia.2023.51.06
PMID:38665984
Fungal Endophytes: Microfactories of Novel Bioactive Compounds with Therapeutic Interventions; A Comprehensive Review on the Biotechnological Developments in the Field of Fungal Endophytic Biology over the Last Decade Gupta A, Meshram V, Gupta M, Goyal S, Qureshi KA, Jaremko M, Shukla KK Biomolecules 25-Jun-2023
PMCID:PMC10377637
doi:10.3390/biom13071038
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A New Essential Oil from the Leaves of Gynoxys rugulosa Muschl. (Asteraceae) Growing in Southern Ecuador: Chemical and Enantioselective Analyses Maldonado YE, Malagón O, Cumbicus N, Gilardoni G Plants (Basel) 14-Feb-2023
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Advances in Fungal Phenaloenones—Natural Metabolites with Great Promise: Biosynthesis, Bioactivities, and an In Silico Evaluation of Their Potential as Human Glucose Transporter 1 Inhibitors Ibrahim SR, Omar AM, Muhammad YA, Alqarni AA, Alshehri AM, Mohamed SG, Abdallah HM, Elfaky MA, Mohamed GA, Xiao J Molecules 11-Oct-2022
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RNA-dependent RNA polymerase (RdRp) natural antiviral inhibitors: a review Leite DR, Mantovani KM, Cordeiro SP, Maia FB, Betim FC, de Bona Sartor E, Montrucchio DP, de Fátima Gaspari Dias J, Miguel OG, Miguel MD Med Chem Res 29-Sep-2022
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doi:10.1007/s00044-022-02963-2
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Microbial Natural Products with Antiviral Activities, Including Anti-SARS-CoV-2: A Review Frediansyah A, Sofyantoro F, Alhumaid S, Al Mutair A, Albayat H, Altaweil HI, Al-Afghani HM, AlRamadhan AA, AlGhazal MR, Turkistani SA, Abuzaid AA, Rabaan AA Molecules 05-Jul-2022
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doi:10.3390/molecules27134305
PMID:35807550
Determining Methyl-Esterification Patterns in Plant-Derived Homogalacturonan Pectins Yu Y, Cui L, Liu X, Wang Y, Song C, Pak U, Mayo KH, Sun L, Zhou Y Front Nutr 01-Jul-2022
PMCID:PMC9330511
doi:10.3389/fnut.2022.925050
PMID:35911105
Ethnobotany of medicinal plants used by the Yao people in Gongcheng County, Guangxi, China Lu Z, Chen H, Lin C, Ou G, Li J, Xu W J Ethnobiol Ethnomed 21-Jun-2022
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Perceiving SARS-CoV-2 Mpro and PLpro dual inhibitors from pool of recognized antiviral compounds of endophytic microbes: an in silico simulation study Prajapati J, Patel R, Rao P, Saraf M, Rawal R, Goswami D Struct Chem 08-Apr-2022
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PMID:35406954
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Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lignans, neolignans and related compounds / Aryltetralin lignans
(6R,7S,8S)-8-(1,3-benzodioxol-5-yl)-3-methoxy-6,7-dimethyl-5,6,7,8-tetrahydronaphthalen-2-ol 101289780 Click to see CC1CC2=CC(=C(C=C2C(C1C)C3=CC4=C(C=C3)OCO4)O)OC 326.40 unknown https://doi.org/10.1248/CPB.56.1143
Kadsuralignan C 16079967 Click to see 358.40 unknown https://doi.org/10.1248/CPB.56.1143
> Lignans, neolignans and related compounds / Dibenzylbutane lignans
Isoanwulignan 135397589 Click to see 328.40 unknown https://doi.org/10.1248/CPB.56.1143
> Lignans, neolignans and related compounds / Furanoid lignans / Tetrahydrofuran lignans / 7,7-epoxylignans
4-[(2R,3S,4R,5R)-5-(4-hydroxy-3,5-dimethoxyphenyl)-3,4-dimethyloxolan-2-yl]-2,6-dimethoxyphenol 98774649 Click to see CC1C(C(OC1C2=CC(=C(C(=C2)OC)O)OC)C3=CC(=C(C(=C3)OC)O)OC)C 404.50 unknown https://doi.org/10.1248/CPB.56.1143
Grandisin 442876 Click to see 432.50 unknown https://doi.org/10.1248/CPB.56.1143
Kadlongirin A 25098692 Click to see 448.50 unknown https://doi.org/10.1248/CPB.56.1143
Kadlongirin B 25022545 Click to see 446.50 unknown https://doi.org/10.1248/CPB.56.1143
> Lipids and lipid-like molecules / Prenol lipids / Monoterpenoids / Bicyclic monoterpenoids
Borneol 64685 Click to see 154.25 unknown https://doi.org/10.1111/J.2042-7158.2010.01119.X
Camphene 6616 Click to see 136.23 unknown https://doi.org/10.1111/J.2042-7158.2010.01119.X
> Lipids and lipid-like molecules / Prenol lipids / Sesquiterpenoids
(1R,2R,4S)-1,6-dimethyl-4-prop-1-en-2-yl-1,2,3,4-tetrahydronaphthalene-2,7-diol 25098693 Click to see 232.32 unknown https://doi.org/10.1248/CPB.56.1143
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones
(1R,2R,4R,10S,11R,13S,14R,17R,19R)-1,11,17-trihydroxy-9,9,14-trimethyl-18-methylidene-17-[(1S)-1-[(2R)-5-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-3,8-dioxapentacyclo[11.7.0.02,4.04,10.014,19]icos-5-en-7-one 162851139 Click to see CC1=CCC(OC1=O)C(C)C2(CCC3(C4CC(C5C(OC(=O)C=CC56C(C4(CC3C2=C)O)O6)(C)C)O)C)O 528.60 unknown https://doi.org/10.1021/NP070247A
(1R,2R,4R,10S,11R,13S,14R,19R)-1,11-dihydroxy-9,9,14-trimethyl-18-methylidene-17-[(1R)-1-[(2R)-5-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-3,8-dioxapentacyclo[11.7.0.02,4.04,10.014,19]icosa-5,16-dien-7-one 162845227 Click to see 510.60 unknown https://doi.org/10.1021/NP070247A
(1R,2R,4R,10S,13S,14R,19R)-1-hydroxy-9,9,14-trimethyl-18-methylidene-17-[(1R)-1-[(2R)-5-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-3,8-dioxapentacyclo[11.7.0.02,4.04,10.014,19]icosa-5,16-dien-7-one 162852220 Click to see 494.60 unknown https://doi.org/10.1021/NP070247A
(1R,4R,10S,11R,13S,14R,17R,19R)-1,11,17-trihydroxy-9,9,14-trimethyl-18-methylidene-17-[(1S)-1-[(2R)-5-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-3,8-dioxapentacyclo[11.7.0.02,4.04,10.014,19]icos-5-en-7-one 163194470 Click to see 528.60 unknown https://doi.org/10.1021/NP070247A
(1R,9R,12S,13R,16R,18R)-1,16-dihydroxy-8,8,13-trimethyl-17-methylidene-16-[(1S)-1-[(2R)-5-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-7-oxatetracyclo[10.7.0.03,9.013,18]nonadeca-2,4-dien-6-one 162873103 Click to see CC1=CCC(OC1=O)C(C)C2(CCC3(C4CCC5C(=CC4(CC3C2=C)O)C=CC(=O)OC5(C)C)C)O 496.60 unknown https://doi.org/10.1021/NP070247A
(1R,9R,12S,13R,16S,18S)-1-hydroxy-8,8,13-trimethyl-17-methylidene-16-[(1R)-1-[(2R)-5-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-7-oxatetracyclo[10.7.0.03,9.013,18]nonadeca-2,4-dien-6-one 162972733 Click to see 480.60 unknown https://doi.org/10.1021/NP070247A
(1R,9R,12S,13R,18R)-1-hydroxy-16-[(1R)-1-[(2S,3S)-3-hydroxy-5-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-8,8,13-trimethyl-17-methylidene-7-oxatetracyclo[10.7.0.03,9.013,18]nonadeca-2,4,15-trien-6-one 163024141 Click to see 494.60 unknown https://doi.org/10.1021/NP070247A
(1R,9R,12S,13R,18R)-1-hydroxy-8,8,13-trimethyl-17-methylidene-16-[(1R)-1-[(2R)-5-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-7-oxatetracyclo[10.7.0.03,9.013,18]nonadeca-2,4,15-trien-6-one 163030502 Click to see 478.60 unknown https://doi.org/10.1021/NP070247A
(1R,9S,10R,12S,13R,16R,18R)-1,10,16-trihydroxy-8,8,13-trimethyl-17-methylidene-16-[(1S)-1-[(2R)-5-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-7-oxatetracyclo[10.7.0.03,9.013,18]nonadeca-2,4-dien-6-one 163036888 Click to see 512.60 unknown https://doi.org/10.1021/NP070247A
(1R,9S,10R,12S,13R,16R)-1,10,16-trihydroxy-8,8,13-trimethyl-17-methylidene-16-[(1S)-1-[(2R)-5-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-7-oxatetracyclo[10.7.0.03,9.013,18]nonadeca-2,4-dien-6-one 163195045 Click to see 512.60 unknown https://doi.org/10.1021/NP070247A
(1R,9S,10R,12S,13R,18R)-1,10-dihydroxy-8,8,13-trimethyl-17-methylidene-16-[(1R)-1-[(2R)-5-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-7-oxatetracyclo[10.7.0.03,9.013,18]nonadeca-2,4,15-trien-6-one 163083293 Click to see CC1=CCC(OC1=O)C(C)C2=CCC3(C4CC(C5C(=CC4(CC3C2=C)O)C=CC(=O)OC5(C)C)O)C 494.60 unknown https://doi.org/10.1021/NP070247A
> Organoheterocyclic compounds / Naphthopyrans
(1R,2S,5R,13R,15R,18S,23S,24S,26R)-13,26-dihydroxy-1,6,6,20,24-pentamethyl-7,22-dioxahexacyclo[13.12.0.02,13.05,11.016,25.018,23]heptacosa-9,11,16(25),19-tetraene-8,21-dione 162939535 Click to see 494.60 unknown https://doi.org/10.1021/NP070247A
(1R,2S,5R,13R,15R,18S,23S,24S,26S)-13-hydroxy-26-methoxy-1,6,6,20,24-pentamethyl-7,22-dioxahexacyclo[13.12.0.02,13.05,11.016,25.018,23]heptacosa-9,11,16(25),19-tetraene-8,21-dione 162996568 Click to see CC1C2C(CC3=C1C(CC4(C3CC5(C4CCC6C(=C5)C=CC(=O)OC6(C)C)O)C)OC)C=C(C(=O)O2)C 508.60 unknown https://doi.org/10.1021/NP070247A
(1R,2S,5R,13S,15R,18S,23R,24S,26S)-13,26-dihydroxy-1,6,6,20,24-pentamethyl-7,22-dioxahexacyclo[13.12.0.02,13.05,11.016,25.018,23]heptacosa-9,11,16(25),19-tetraene-8,21-dione 24178992 Click to see 494.60 unknown https://doi.org/10.1021/NP070247A
(1S,2R,4R,12R,15S,16S,18R,19R,20R,21S,26S)-4,18-dihydroxy-11,11,16,20,24-pentamethyl-10,22,28-trioxaheptacyclo[17.8.1.01,19.02,16.04,15.06,12.021,26]octacosa-5,7,24-triene-9,23-dione 163105917 Click to see 510.60 unknown https://doi.org/10.1021/NP070247A
13,26-Dihydroxy-1,6,6,20,24-pentamethyl-7,22-dioxahexacyclo[13.12.0.02,13.05,11.016,25.018,23]heptacosa-9,11,16(25),19-tetraene-8,21-dione 73041515 Click to see 494.60 unknown https://doi.org/10.1021/OL052161J
Kadlongilactone A 11648913 Click to see 494.60 unknown https://doi.org/10.1021/NP070247A
https://doi.org/10.1021/OL052161J
Kadlongilactone C 24178896 Click to see 508.60 unknown https://doi.org/10.1021/NP070247A
Kadlongilactone E 24178993 Click to see 508.60 unknown https://doi.org/10.1021/NP070247A
> Organoheterocyclic compounds / Naphthopyrans / Naphthopyranones
(1R,2S,13R,15R,18S,23S,24S)-13-hydroxy-1,6,6,20,24-pentamethyl-7,22-dioxahexacyclo[13.12.0.02,13.05,11.016,25.018,23]heptacosa-9,11,16(25),19-tetraene-8,21,26-trione 163185740 Click to see CC1C2C(CC3=C1C(=O)CC4(C3CC5(C4CCC6C(=C5)C=CC(=O)OC6(C)C)O)C)C=C(C(=O)O2)C 492.60 unknown https://doi.org/10.1021/NP070247A
(1R,2S,5R,13R,15R,18S,23S,24S)-13-hydroxy-1,6,6,20,24-pentamethyl-7,22-dioxahexacyclo[13.12.0.02,13.05,11.016,25.018,23]heptacosa-9,11,16(25),19-tetraene-8,21,26-trione 162982798 Click to see 492.60 unknown https://doi.org/10.1021/NP070247A
13-Hydroxy-1,6,6,20,24-pentamethyl-7,22-dioxahexacyclo[13.12.0.02,13.05,11.016,25.018,23]heptacosa-9,11,16(25),19-tetraene-8,21,26-trione 73036695 Click to see 492.60 unknown https://doi.org/10.1021/OL052161J
> Organoheterocyclic compounds / Pyrans / Pyranones and derivatives / Dihydropyranones
8,8,13,17-Tetramethyl-16-[1-(5-methyl-6-oxo-2,3-dihydropyran-2-yl)ethyl]-7-oxatetracyclo[10.7.0.03,9.013,17]nonadeca-1(12),2,4-trien-6-one 435759 Click to see 464.60 unknown https://doi.org/10.1248/CPB.54.129
Schisanlactone A 44560613 Click to see CC1=CCC(OC1=O)C(C)C2CCC3(C2(CCC4=C3CCC5C(=C4)C=CC(=O)OC5(C)C)C)C 464.60 unknown https://doi.org/10.1248/CPB.54.129
> Phenylpropanoids and polyketides / Tannins / Hydrolyzable tannins
(3-Hydroxy-4,5,19-trimethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.02,7.014,18]nonadeca-1(19),2,4,6,12,14(18)-hexaen-11-yl) 3-phenylprop-2-enoate 73036881 Click to see CC1CC2=CC(=C(C(=C2C3=C(C4=C(C=C3C(C1C)OC(=O)C=CC5=CC=CC=C5)OCO4)OC)O)OC)OC 532.60 unknown https://doi.org/10.1248/CPB.54.129
[(9R,10R,11S)-3-hydroxy-4,5,19-trimethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.02,7.014,18]nonadeca-1(19),2,4,6,12,14(18)-hexaen-11-yl] acetate 162941346 Click to see CC1CC2=CC(=C(C(=C2C3=C(C4=C(C=C3C(C1C)OC(=O)C)OCO4)OC)O)OC)OC 444.50 unknown https://doi.org/10.1248/CPB.54.129
[(9S,10R,11S)-3-hydroxy-4,5,19-trimethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.02,7.014,18]nonadeca-1(19),2,4,6,12,14(18)-hexaen-11-yl] benzoate 162897128 Click to see 506.50 unknown https://doi.org/10.1248/CPB.54.129
[(9S,10R,11S)-3-hydroxy-4,5,19-trimethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.02,7.014,18]nonadeca-1(19),2,4,6,12,14(18)-hexaen-11-yl] propanoate 163092412 Click to see 458.50 unknown https://doi.org/10.1248/CPB.54.129
[(9S,10S,11R)-3-hydroxy-4,5,19-trimethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.02,7.014,18]nonadeca-1(19),2,4,6,12,14(18)-hexaen-11-yl] (E)-3-phenylprop-2-enoate 162930139 Click to see 532.60 unknown https://doi.org/10.1248/CPB.54.129
kadsuphilol A 14827760 Click to see CC1CC2=CC(=C(C(=C2C3=C(C4=C(C=C3C(C1C)O)OCO4)OC)O)OC)OC 402.40 unknown https://doi.org/10.1248/CPB.54.129
longipedumin A 11635141 Click to see 532.60 unknown https://doi.org/10.1248/CPB.54.129

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