Hymenoxys odorata - Unknown
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Internal ID UUID643fce6667c67999582758
Scientific name Hymenoxys odorata
Authority DC.
First published in Icon. Sel. Pl. [Delessert] 4: 18, t. 42. 1840 [1839, publ Feb 1840]

Description Top

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Hymenoxys odorata, also known as bitter rubberweed or western bitterweed, is a flowering plant found in dry regions of the southwestern and south-central United States and northern Mexico. It is an annual herb with branching stems and short, pointed leaves. The plant produces bright yellow flowers and is toxic to livestock, particularly sheep. The toxic compounds, hymenovin and hymenoxon, can cause inflammation of the stomach, renal necrosis, and toxic hepatitis, and can be fatal if ingested in large amounts. While sheep tend to avoid the plant due to its bitter taste, they may still consume it if other forage is not available.

Synonyms Top

Scientific name Authority First published in
Picradenia odorata Britton Ill. Fl. N. U.S. 3: 449 (1898)
Picradenia multiflora Greene Pittonia 3(18): 273 (1898)
Ptilepida odorata (DC.) Britton Mem. Torrey Bot. Club 5: 340 (1894)
Hymenoxys multiflora Rydb. Bull. Torrey Bot. Club 33: 157 (1906)
Actinella odorata A.Gray Mem. Amer. Acad. 4(Pl. Fendl.): 101. 1849
Actinea odorata Kuntze Revis. Gen. Pl. 1: 303 (1891)
Cephalophora anthemoides Less. Linnaea 6: 518 (1831)
Phileozera multiflora Buckley Proc. Acad. Nat. Sci. Philadelphia 1861: (1862)

Common names Top

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Language Common/alternative name
English bitter rubberweed

Subspecies (abbr. subsp./ssp.) Top

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No subspecies added yet.

Varieties (abbr. var.) Top

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Subvarieties (abbr. subvar.) Top

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Forms (abbr. f.) Top

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Germination/Propagation Top

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No germination or propagation data was added yet.

Distribution (via POWO/KEW) Top

Legend for the distribution data:
- Doubtful data
- Extinct
- Introduced
- Native
  • Northern America
    • Mexico
      • Mexico Northeast
      • Mexico Northwest
    • North-central U.S.A.
      • Kansas
      • Oklahoma
    • Northwestern U.S.A.
      • Colorado
    • South-central U.S.A.
      • New Mexico
      • Texas
    • Southwestern U.S.A.
      • Arizona
      • California

Links to other databases Top

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Database ID/link to page
World Flora Online wfo-0000081063
Flora of Alabama 823
USDA Plants HYOD
Tropicos 2702710
KEW urn:lsid:ipni.org:names:225320-1
The Plant List gcc-3762
Open Tree Of Life 3900050
NCBI Taxonomy 2741199
Nature Serve 2.157308
IPNI 225320-1
iNaturalist 77478
GBIF 3150162
Freebase /m/041636r
EPPO HYXOD
EOL 468043
Calflora (Californian flora) 4305
USDA GRIN 104355
Wikipedia Hymenoxys_odorata

Genomes (via NCBI) Top

No reference genome is available on NCBI yet. We are constantly monitoring for new data.

Scientific Literature Top

Below are displayed the latest 15 articles published in PMC (PubMed Central®) and other sources (DOI number only)!
If you wish to see all the related articles click here.
Title Authors Publication Released IDs
H N/A Saunders Comprehensive Veterinary Dictionary 16-Oct-2020
PMCID:PMC9771681
doi:10.1016/B978-0-7020-7463-9.50016-1
Cytotoxicity of the Sesquiterpene Lactones, Ivalin and Parthenolide in Murine Muscle Cell Lines and Their Effect on Desmin, a Cytoskeletal Intermediate Filament Botha CJ, Mathe YZ, Ferreira GC, Venter EA Toxins (Basel) 18-Jul-2020
PMCID:PMC7404988
doi:10.3390/toxins12070459
PMID:32708381
The use of biochar in animal feeding Schmidt HP, Hagemann N, Draper K, Kammann C PeerJ 31-Jul-2019
PMCID:PMC6679646
doi:10.7717/peerj.7373
PMID:31396445
Repeated-dose toxicity of common ragweed on rats Kiss T, Szabó A, Oszlánczi G, Lukács A, Tímár Z, Tiszlavicz L, Csupor D PLoS One 04-May-2017
PMCID:PMC5417505
doi:10.1371/journal.pone.0176818
PMID:28472131
Quantitation of hymenoxon and related sesquiterpene lactones Hyeong L. Kim, Stephen H. Safe, Millard C. Calhoun American Chemical Society (ACS) 10-Mar-2005
doi:10.1021/JF00078A010
Sesquiterpene lactones and a C20 aliphatic lactone from texas bitterweed, Hymenoxys odorata Feng Gao, Huiping Wang, Tom J. Mabry, William H. Watson, Ram P. Kashyap Elsevier BV 25-Jul-2002
doi:10.1016/0031-9422(90)85116-W
Alkylation of deoxyguanosine by the sesquiterpene lactone hymenoxon. Sylvia VL, Joe CO, Stipanovic RD, Kim HL, Busbee DL Toxicol Lett 01-Dec-1985
doi:10.1016/0378-4274(85)90026-8
PMID:4089888
Inactivation of catalase with 3-amino-1,2,4-triazole: an indirect irreversible mechanism. Williams RN, Delamere NA, Paterson CA Biochem Pharmacol 15-Sep-1985
doi:10.1016/0006-2952(85)90364-8
PMID:4038347
Hymenovin. major toxic constituent of Western bitterweed (Hymenoxys odorata DC.). Ivie GW, Witzel DA, Herz W, Kannan R, Norman JO, Rushing DD, Johnson JH, Rowe LD, Veech JA J Agric Food Chem 01-Sep-1975
doi:10.1021/JF60201A051
PMID:1159179

Phytochemical Profile Top

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Below are displayed the proven (via scientific papers) natural compounds!
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Name PubChem ID Canonical SMILES MW Found in Proof
> Lipids and lipid-like molecules / Fatty Acyls / Fatty acid esters
(11-Hydroxy-1,9-dimethyl-4-methylidene-5-oxo-6,13-dioxatricyclo[8.4.0.03,7]tetradecan-14-yl) 2-methylbutanoate 14488516 Click to see CCC(C)C(=O)OC1C2(CC3C(CC(C2C(CO1)O)C)OC(=O)C3=C)C 366.40 unknown https://doi.org/10.1016/0031-9422(90)85116-W
[(1S,3R,7S,9R,10S,11R,14S)-11-hydroxy-1,9-dimethyl-4-methylidene-5-oxo-6,13-dioxatricyclo[8.4.0.03,7]tetradecan-14-yl] (2R)-2-methylbutanoate 163028669 Click to see CCC(C)C(=O)OC1C2(CC3C(CC(C2C(CO1)O)C)OC(=O)C3=C)C 366.40 unknown https://doi.org/10.1016/0031-9422(90)85116-W
CID 14488518 14488518 Click to see CCC(C)C(=O)OC1C2(CC3C(CC(C2C(CO1)O)C)OC(=O)C3=C)C 366.40 unknown https://doi.org/10.1016/0031-9422(90)85116-W
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones / Sesquiterpene lactones / Ambrosanolides and secoambrosanolides
(3aR,5R,5aS,7R,8R,8aS,9aR)-7,8-dihydroxy-5,8a-dimethyl-1-methylidene-4,5,5a,6,7,8,9,9a-octahydro-3aH-azuleno[6,5-b]furan-2-one 12304241 Click to see CC1CC2C(CC3(C1CC(C3O)O)C)C(=C)C(=O)O2 266.33 unknown https://doi.org/10.1016/0031-9422(90)85116-W
(3aR,7aalpha,9aalpha)-Dodecahydro-5beta,6beta-dihydroxy-4abeta,8beta-dimethyl-3-methyleneazuleno[6,5-b]furan-2-one 4617986 Click to see CC1CC2C(CC3(C1CC(C3O)O)C)C(=C)C(=O)O2 266.33 unknown https://doi.org/10.1016/0031-9422(90)85116-W
[(1R,3aR,5R,5aS,6R,7R,8R,8aS,9aR)-7,8-diacetyloxy-1,5,8a-trimethyl-2-oxo-1,3a,4,5,5a,6,7,8,9,9a-decahydroazuleno[6,5-b]furan-6-yl] acetate 14488513 Click to see CC1CC2C(CC3(C1C(C(C3OC(=O)C)OC(=O)C)OC(=O)C)C)C(C(=O)O2)C 410.50 unknown https://doi.org/10.1016/0031-9422(90)85116-W
Hymenograndin 171019 Click to see CC1CC2C(CC3(C1C(C(C3O)OC(=O)C)OC(=O)C)C)C(=C)C(=O)O2 366.40 unknown https://doi.org/10.1016/0031-9422(90)85116-W
Hymenolane 173848 Click to see CC1CC2C(CC3(C1C(C(C3OC(=O)C)OC(=O)C)OC(=O)C)C)C(C(=O)O2)C 410.50 unknown https://doi.org/10.1016/0031-9422(90)85116-W
Hymenolane, from hymenoxys odorata DC 319941 Click to see CC1CC2C(CC3(C1C(C(C3OC(=O)C)OC(=O)C)OC(=O)C)C)C(C(=O)O2)C 410.50 unknown https://doi.org/10.1016/0031-9422(90)85116-W
> Lipids and lipid-like molecules / Prenol lipids / Terpene lactones / Sesquiterpene lactones / Guaianolides and derivatives
(4,9,13-Trimethyl-5-oxo-6,14-dioxatetracyclo[8.4.0.01,13.03,7]tetradecan-11-yl) 2-methylbut-2-enoate 162983921 Click to see CC=C(C)C(=O)OC1CC2(C3(C1C(CC4C(C3)C(C(=O)O4)C)C)O2)C 348.40 unknown https://doi.org/10.1016/0031-9422(90)85116-W
[(1S,3R,4R,7R,9R,10R,11S,13R)-4,9,13-trimethyl-5-oxo-6,14-dioxatetracyclo[8.4.0.01,13.03,7]tetradecan-11-yl] (Z)-2-methylbut-2-enoate 14488524 Click to see CC=C(C)C(=O)OC1CC2(C3(C1C(CC4C(C3)C(C(=O)O4)C)C)O2)C 348.40 unknown https://doi.org/10.1016/0031-9422(90)85116-W
[(1S,3R,4S,7R,9R,10R,11S,13R)-4,9,13-trimethyl-5-oxo-6,14-dioxatetracyclo[8.4.0.01,13.03,7]tetradecan-11-yl] (Z)-2-methylbut-2-enoate 14488523 Click to see CC=C(C)C(=O)OC1CC2(C3(C1C(CC4C(C3)C(C(=O)O4)C)C)O2)C 348.40 unknown https://doi.org/10.1016/0031-9422(90)85116-W
Florilenalin 442243 Click to see CC1(CC(C2C1CC3C(CC2=C)OC(=O)C3=C)O)O 264.32 unknown https://doi.org/10.1016/0031-9422(90)85116-W
> Organoheterocyclic compounds / Furofurans
(2-Hydroxy-2,6,11-trimethyl-10-oxo-9,14-dioxatetracyclo[9.2.1.01,5.08,12]tetradecan-4-yl) 2-methylbut-2-enoate 163017722 Click to see CC=C(C)C(=O)OC1CC(C23C1C(CC4C(C2)C(O3)(C(=O)O4)C)C)(C)O 364.40 unknown https://doi.org/10.1016/0031-9422(90)85116-W
[(1R,2R,4S,5R,6R,8R,11S,12S)-2-hydroxy-2,6,11-trimethyl-10-oxo-9,14-dioxatetracyclo[9.2.1.01,5.08,12]tetradecan-4-yl] (Z)-2-methylbut-2-enoate 101526593 Click to see CC=C(C)C(=O)OC1CC(C23C1C(CC4C(C2)C(O3)(C(=O)O4)C)C)(C)O 364.40 unknown https://doi.org/10.1016/0031-9422(90)85116-W
> Organoheterocyclic compounds / Lactones / Delta valerolactones
(4S,6S)-4-hydroxy-6-pentadecyloxan-2-one 14488531 Click to see CCCCCCCCCCCCCCCC1CC(CC(=O)O1)O 326.50 unknown https://doi.org/10.1016/0031-9422(90)85116-W
> Organoheterocyclic compounds / Lactones / Gamma butyrolactones
(1S,3aR,5R,5aS,6S,8R,9aR)-6,8-dihydroxy-1,5,8-trimethyl-1,3a,4,5,5a,6,7,9a-octahydroazuleno[6,5-b]furan-2-one 101526592 Click to see CC1CC2C(C=C3C1C(CC3(C)O)O)C(C(=O)O2)C 266.33 unknown https://doi.org/10.1016/0031-9422(90)85116-W
(1S,3R,7R,9R,10R,14R)-14-hydroxy-1,9-dimethyl-4-methylidene-6,13-dioxatricyclo[8.4.0.03,7]tetradec-11-en-5-one 14488520 Click to see CC1CC2C(CC3(C1C=COC3O)C)C(=C)C(=O)O2 264.32 unknown https://doi.org/10.1016/0031-9422(90)85116-W
(1S,3R,7S,9R,10R,14R)-14-hydroxy-1,9-dimethyl-4-methylidene-6,13-dioxatricyclo[8.4.0.03,7]tetradec-11-en-5-one 101526589 Click to see CC1CC2C(CC3(C1C=COC3O)C)C(=C)C(=O)O2 264.32 unknown https://doi.org/10.1016/0031-9422(90)85116-W
14-Hydroxy-1,9-dimethyl-4-methylidene-6,13-dioxatricyclo[8.4.0.03,7]tetradec-11-en-5-one 14488519 Click to see CC1CC2C(CC3(C1C=COC3O)C)C(=C)C(=O)O2 264.32 unknown https://doi.org/10.1016/0031-9422(90)85116-W
6,8-Dihydroxy-1,5,8-trimethyl-1,3a,4,5,5a,6,7,9a-octahydroazuleno[6,5-b]furan-2-one 14488528 Click to see CC1CC2C(C=C3C1C(CC3(C)O)O)C(C(=O)O2)C 266.33 unknown https://doi.org/10.1016/0031-9422(90)85116-W
> Organoheterocyclic compounds / Oxanes
(1S,3R,7R,9R,10S,12R,14S)-12,14-dihydroxy-1,9-dimethyl-4-methylidene-6,13-dioxatricyclo[8.4.0.03,7]tetradecan-5-one 14488511 Click to see CC1CC2C(CC3(C1CC(OC3O)O)C)C(=C)C(=O)O2 282.33 unknown https://doi.org/10.1016/0031-9422(90)85116-W
(1S,3R,7R,9R,10S,12S,14S)-12,14-dihydroxy-1,9-dimethyl-4-methylidene-6,13-dioxatricyclo[8.4.0.03,7]tetradecan-5-one 14488512 Click to see CC1CC2C(CC3(C1CC(OC3O)O)C)C(=C)C(=O)O2 282.33 unknown https://doi.org/10.1016/0031-9422(90)85116-W
(1S,3R,7R,9S,10S,12R,14S)-12,14-dihydroxy-1,9-dimethyl-4-methylidene-6,13-dioxatricyclo[8.4.0.03,7]tetradecan-5-one 162889809 Click to see CC1CC2C(CC3(C1CC(OC3O)O)C)C(=C)C(=O)O2 282.33 unknown https://doi.org/10.1016/0031-9422(90)85116-W
(1S,3R,7R,9S,10S,12S,14S)-12,14-dihydroxy-1,9-dimethyl-4-methylidene-6,13-dioxatricyclo[8.4.0.03,7]tetradecan-5-one 163189112 Click to see CC1CC2C(CC3(C1CC(OC3O)O)C)C(=C)C(=O)O2 282.33 unknown https://doi.org/10.1016/0031-9422(90)85116-W
5,7-Dihydroxy-4a,9-dimethyl-3-methylidenedecahydrofuro[2',3':5,6]cyclohepta[1,2-c]pyran-2(3h)-one 107943 Click to see CC1CC2C(CC3(C1CC(OC3O)O)C)C(=C)C(=O)O2 282.33 unknown https://doi.org/10.1016/0031-9422(90)85116-W
Hymenoxon 42295 Click to see CC1CC2C(CC3(C1CC(OC3O)O)C)C(=C)C(=O)O2 282.33 unknown https://doi.org/10.1021/JF60201A051
https://doi.org/10.1016/0006-2952(85)90364-8
https://doi.org/10.1021/JF00078A010
> Phenylpropanoids and polyketides / Flavonoids / Flavones / 2-prenylated flavones
3,5,7-Trihydroxy-2-[8-hydroxy-2,2-dimethyl-5-(3-methylbut-2-enyl)-3,4-dihydrochromen-6-yl]-8-(2-methylbut-3-en-2-yl)chromen-4-one 14542431 Click to see CC(=CCC1=C2CCC(OC2=C(C=C1C3=C(C(=O)C4=C(O3)C(=C(C=C4O)O)C(C)(C)C=C)O)O)(C)C)C 506.60 unknown https://doi.org/10.1016/0031-9422(90)85116-W
> Phenylpropanoids and polyketides / Flavonoids / O-methylated flavonoids / 8-O-methylated flavonoids
Hymenoxin 171488 Click to see COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C(=C(C(=C3O2)OC)O)OC)O)OC 374.30 unknown https://doi.org/10.1016/0378-4274(85)90026-8

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